Works by Gmyr, Valery

Results: 33

The role of the glucagon‐FGF21 axis in improving beta cell function during glucose intolerance and SGLT2 inhibition.

Published in:

Diabetes, Obesity & Metabolism, 2025, v. 27, n. 2, p. 885, doi. 10.1111/dom.16089

By:

Moreno‐Lopez, Maria;
Louvet, Isaline;
Delalleau, Nathalie;
Acosta‐Montalvo, Ana;
Thevenet, Julien;
Pasquetti, Gianni;
Gmyr, Valery;
Kerr‐Conte, Julie;
Pattou, Francois;
Bonner, Caroline;
Saponaro, Chiara

Publication type:

Article

Pharmacological approach to understanding the control of insulin secretion in human islets.

Published in:

Diabetes, Obesity & Metabolism, 2017, v. 19, n. 8, p. 1061, doi. 10.1111/dom.12887

By:

Henquin, Jean‐Claude;
Dufrane, Denis;
Gmyr, Valery;
Kerr‐Conte, Julie;
Nenquin, Myriam

Publication type:

Article

Sodium lactate improves renal microvascular thrombosis compared to sodium bicarbonate and 0.9% NaCl in a porcine model of endotoxic shock: an experimental randomized open label controlled study.

Published in:

Annals of Intensive Care, 2018, v. 8, n. 1, p. 0, doi. 10.1186/s13613-018-0367-9

By:

Duburcq, Thibault;
Durand, Arthur;
Tournoys, Antoine;
Gnemmi, Viviane;
Gmyr, Valery;
Pattou, François;
Jourdain, Mercedes;
Tamion, Fabienne;
Besnier, Emmanuel;
Préau, Sebastien;
Parmentier-Decrucq, Erika;
Mathieu, Daniel;
Poissy, Julien;
Favory, Raphaël

Publication type:

Article

Coxsackievirus-B4 Infection of Human Primary Pancreatic Ductal Cell Cultures Results in Impairment of Differentiation into Insulin-Producing Cells.

Published in:

Viruses (1999-4915), 2019, v. 11, n. 7, p. 597, doi. 10.3390/v11070597

By:

Bertin, Antoine;
Sane, Famara;
Gmyr, Valery;
Lobert, Delphine;
Dechaumes, Arthur;
Kerr-Conte, Julie;
Pattou, François;
Hober, Didier

Publication type:

Article

Comparison of fluid balance and hemodynamic and metabolic effects of sodium lactate versus sodium bicarbonate versus 0.9% NaCl in porcine endotoxic shock: a randomized, open-label, controlled study.

Published in:

2017

By:

Duburcq, Thibault;
Durand, Arthur;
Dessein, Anne-Frédérique;
Vamecq, Joseph;
Vienne, Jean-Claude;
Dobbelaere, Dries;
Mention, Karine;
Douillard, Claire;
Maboudou, Patrice;
Gmyr, Valery;
Pattou, François;
Jourdain, Mercé;
Tamion, Fabienne;
Poissy, Julien;
Mathieu, Daniel;
Favory, Raphaël

Publication type:

journal article

Evidence for a membrane carbonic anhydrase IV anchored by its C-terminal peptide in normal human pancreatic ductal cells.

Published in:

Histochemistry & Cell Biology, 2004, v. 121, n. 2, p. 91, doi. 10.1007/s00418-003-0616-2

By:

Fanjul, Marjorie;
Alvarez, Laetitia;
Salvador, Christel;
Gmyr, Valéry;
Kerr-Conte, Julie;
Pattou, François;
Carter, Nicholas;
Hollande, Etienne

Publication type:

Article

The Class I Histone Deacetylase Inhibitor MS-275 Prevents Pancreatic Beta Cell Death Induced by Palmitate.

Published in:

Journal of Diabetes Research, 2014, p. 1, doi. 10.1155/2014/195739

By:

Plaisance, Valérie;
Rolland, Laure;
Gmyr, Valéry;
Annicotte, Jean-Sébastien;
Kerr-Conte, Julie;
Pattou, François;
Abderrahmani, Amar

Publication type:

Article

JNK3 Is Required for the Cytoprotective Effect of Exendin 4.

Published in:

Journal of Diabetes Research, 2014, p. 1, doi. 10.1155/2014/814854

By:

Ezanno, Hélène;
Pawlowski, Valérie;
Abdelli, Saida;
Boutry, Raphael;
Gmyr, Valery;
Kerr-Conte, Julie;
Bonny, Christophe;
Pattou, François;
Abderrahmani, Amar

Publication type:

Article

Hypertonic sodium lactate improves fluid balance and hemodynamics in porcine endotoxic shock.

Published in:

Critical Care, 2014, v. 18, n. 4, p. 2, doi. 10.1186/s13054-014-0467-3

By:

Duburcq, Thibault;
Favory, Raphaël;
Mathieu, Daniel;
Hubert, Thomas;
Mangalaboyi, Jacques;
Gmyr, Valery;
Quintane, Laurence;
Maboudou, Patrice;
Pattou, François;
Jourdain, Mercé

Publication type:

Article

Hypertonic sodium lactate improves fluid balance and hemodynamics in porcine endotoxic shock.

Published in:

2014

By:

Duburcq, Thibault;
Favory, Raphaël;
Mathieu, Daniel;
Hubert, Thomas;
Mangalaboyi, Jacques;
Gmyr, Valery;
Quintane, Laurence;
Maboudou, Patrice;
Pattou, François;
Jourdain, Mercé

Publication type:

journal article

Erratum. Ten-Year Outcome of Islet Alone or Islet After Kidney Transplantation in Type 1 Diabetes: A Prospective Parallel-Arm Cohort Study. Diabetes Care 2019;42:2042-2049.

Published in:

2020

By:

Vantyghem, Marie-Christine;
Chetboun, Mikael;
Gmyr, Valéry;
Jannin, Arnaud;
Espiard, Stéphanie;
Le Mapihan, Kristell;
Raverdy, Violeta;
Delalleau, Nathalie;
Machuron, François;
Hubert, Thomas;
Frimat, Marie;
Van Belle, Eric;
Hazzan, Marc;
Pigny, Pascal;
Noel, Christian;
Caiazzo, Robert;
Kerr-Conte, Julie;
Pattou, François

Publication type:

journal article

Ten-Year Outcome of Islet Alone or Islet After Kidney Transplantation in Type 1 Diabetes: A Prospective Parallel-Arm Cohort Study.

Published in:

2019

By:

Vantyghem, Marie-Christine;
Chetboun, Mikael;
Gmyr, Valéry;
Jannin, Arnaud;
Espiard, Stéphanie;
Le Mapihan, Kristell;
Raverdy, Violeta;
Delalleau, Nathalie;
Machuron, François;
Hubert, Thomas;
Frimat, Marie;
Van Belle, Eric;
Hazzan, Marc;
Pigny, Pascal;
Noel, Christian;
Caiazzo, Robert;
Kerr-Conte, Julie;
Pattou, François;
Members of the Spanish Back Pain Research Network Task Force for the Improvement of Inter-Disciplinary Management of Spinal Metastasis

Publication type:

journal article

The challenge of HLA donor specific antibodies in the management of pancreatic islet transplantation: an illustrative case-series.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-16782-3

By:

Maanaoui, Mehdi;
Chetboun, Mikael;
Top, Isabelle;
Elsermans, Vincent;
Kerr-Conte, Julie;
Le Mapihan, Kristell;
Defrance, Frederique;
Gmyr, Valéry;
Hubert, Thomas;
Labalette, Myriam;
Hazzan, Marc;
Vantyghem, Marie-Christine;
Pattou, François

Publication type:

Article

Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL.

Published in:

PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0163046

By:

Plaisance, Valérie;
Brajkovic, Saška;
Tenenbaum, Mathie;
Favre, Dimitri;
Ezanno, Hélène;
Bonnefond, Amélie;
Bonner, Caroline;
Gmyr, Valéry;
Kerr-Conte, Julie;
Gauthier, Benoit R.;
Widmann, Christian;
Waeber, Gérard;
Pattou, François;
Froguel, Philippe;
Abderrahmani, Amar

Publication type:

Article

Improvement of Electrophysiological Neuropathy After Islet Transplantation for Type 1 Diabetes: A 5-Year Prospective Study.

Published in:

Diabetes Care, 2014, v. 37, n. 6, p. e141, doi. 10.2337/dc14-0320

By:

Vantyghem, Marie-Christine;
Quintin, Delphine;
Caiazzo, Robert;
Leroy, Clara;
Raverdy, Violeta;
Cassim, François;
Glowacki, François;
Hubert, Thomas;
Gmyr, Valery;
Noel, Christian;
Kerr-Conte, Julie;
Pattou, François

Publication type:

Article

Primary Graft Function, Metabolic Control, and Graft Survival After Islet Transplantation.

Published in:

Diabetes Care, 2009, v. 32, n. 8, p. 1473, doi. 10.2337/dc08-1685

By:

Vantyghem, Marie-Christine;
Kerr-Conte, Julie;
Arnalsteen, Laurent;
Sergent, Geraldine;
Defrance, Frederique;
Gmyr, Valery;
Declerck, Nicole;
Raverdy, Violeta;
Vandewalle, Brigitte;
Pigny, Pascal;
Noel, Christian;
Pattou, Francois

Publication type:

Article

The NERP-4–SNAT2 axis regulates pancreatic β-cell maintenance and function.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43976-8

By:

Zhang, Weidong;
Miura, Ayako;
Abu Saleh, Md Moin;
Shimizu, Koichiro;
Mita, Yuichiro;
Tanida, Ryota;
Hirako, Satoshi;
Shioda, Seiji;
Gmyr, Valery;
Kerr-Conte, Julie;
Pattou, Francois;
Jin, Chunhuan;
Kanai, Yoshikatsu;
Sasaki, Kazuki;
Minamino, Naoto;
Sakoda, Hideyuki;
Nakazato, Masamitsu

Publication type:

Article

Pancreatic islet transplantation under the kidney capsule of mice: model of refinement for molecular and ex-vivo graft analysis.

Published in:

Laboratory Animals, 2021, v. 55, n. 5, p. 408, doi. 10.1177/00236772211004051

By:

Thévenet, Julien;
Gmyr, Valery;
Delalleau, Nathalie;
Pattou, François;
Kerr-Conte, Julie

Publication type:

Article

Continuous glucose monitoring after islet transplantation in type 1 diabetes: an excellent graft function (β-score greater than 7) Is required to abrogate hyperglycemia, whereas a minimal function is necessary to suppress severe hypoglycemia (β-score greater than 3).

Published in:

2012

By:

Vantyghem MC;
Raverdy V;
Balavoine AS;
Defrance F;
Caiazzo R;
Arnalsteen L;
Gmyr V;
Hazzan M;
Noël C;
Kerr-Conte J;
Pattou F;
Vantyghem, Marie-Christine;
Raverdy, Violeta;
Balavoine, Anne-Sophie;
Defrance, Frédérique;
Caiazzo, Robert;
Arnalsteen, Laurent;
Gmyr, Valéry;
Hazzan, Marc;
Noël, Christian

Publication type:

journal article

Correction: Pharmaceutical targeting of the cannabinoid type 1 receptor impacts the crosstalk between immune cells and islets to reduce insulitis in humans.

Published in:

2025

By:

Wreven, Elise;
de Adana, María Soledad Ruiz;
Hardivillé, Stéphan;
Gmyr, Valery;
Kerr-Conte, Julie;
Chetboun, Mikael;
Pasquetti, Gianni;
Delalleau, Nathalie;
Thévenet, Julien;
Coddeville, Anaïs;
Herrera, María José Vallejo;
Hinden, Liad;
Espínola, Inmaculada Concepción Benavides;
Duro, Mireia Gómez;
Salido, Lourdes Sanchez;
Linares, Francisca;
Bermúdez-Silva, Francisco-Javier;
Tam, Joseph;
Bonner, Caroline;
Egan, Josephine M.

Publication type:

Correction Notice

Pharmaceutical targeting of the cannabinoid type 1 receptor impacts the crosstalk between immune cells and islets to reduce insulitis in humans.

Published in:

Diabetologia, 2024, v. 67, n. 9, p. 1877, doi. 10.1007/s00125-024-06193-6

By:

Wreven, Elise;
Ruiz de Adana, María Soledad;
Hardivillé, Stéphan;
Gmyr, Valery;
Kerr-Conte, Julie;
Chetboun, Mikael;
Pasquetti, Gianni;
Delalleau, Nathalie;
Thévenet, Julien;
Coddeville, Anaïs;
Vallejo Herrera, María José;
Hinden, Liad;
Benavides Espínola, Inmaculada Concepción;
Gómez Duro, Mireia;
Sanchez Salido, Lourdes;
Linares, Francisca;
Bermúdez-Silva, Francisco-Javier;
Tam, Joseph;
Bonner, Caroline;
Egan, Josephine M.

Publication type:

Article

Primary Graft Function and 5Year Insulin Independence After Pancreas and Islet Transplantation for Type 1 Diabetes: A Retrospective Parallel Cohort Study.

Published in:

Transplant International, 2024, p. 1, doi. 10.3389/ti.2023.11950

By:

Chetboun, Mikael;
Masset, Christophe;
Maanaoui, Mehdi;
Defrance, Frédérique;
Gmyr, Valéry;
Raverdy, Violeta;
Hubert, Thomas;
Bonner, Caroline;
Supiot, Lisa;
Kerleau, Clarisse;
Blancho, Gilles;
Branchereau, Julien;
Karam, Georges;
Chelghaf, Ismaël;
Houzet, Aurélie;
Giral, Magali;
Garandeau, Claire;
Dantal, Jacques;
Mapihan, Kristell Le;
Jannin, Arnaud

Publication type:

Article

Effects of subtotal pancreatectomy and long‐term glucose and lipid overload on insulin secretion and glucose homeostasis in minipigs.

Published in:

Endocrinology, Diabetes & Metabolism, 2023, v. 6, n. 4, p. 1, doi. 10.1002/edm2.425

By:

Goutchtat, Rébecca;
Quenon, Audrey;
Clarisse, Manon;
Delalleau, Nathalie;
Coddeville, Anaïs;
Gobert, Mathilde;
Gmyr, Valéry;
Kerr‐Conte, Julie;
Pattou, François;
Hubert, Thomas

Publication type:

Article

Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion.

Published in:

Nature Medicine, 2015, v. 21, n. 5, p. 512, doi. 10.1038/nm.3828

By:

Bonner, Caroline;
Kerr-Conte, Julie;
Gmyr, Valéry;
Queniat, Gurvan;
Moerman, Ericka;
Thévenet, Julien;
Beaucamps, Cédric;
Delalleau, Nathalie;
Popescu, Iuliana;
Malaisse, Willy J;
Sener, Abdullah;
Deprez, Benoit;
Abderrahmani, Amar;
Staels, Bart;
Pattou, François

Publication type:

Article

Adult human cytokeratin 19-positive cells reexpress insulin promoter factor 1 in vitro: further evidence for pluripotent pancreatic stem cells in humans.

Published in:

2000

By:

Gmyr, Valery;
Kerr-Conte, Julie;
Belaich, Sandrine;
Vandewalle, Brigitte;
Leteurtre, Emmanuelle;
Vantyghem, Marie Christine;
Lecomte-Houcke, Martine;
Proye, Charles;
Lefebvre, Jean;
Pattou, Francois;
Gmyr, V;
Kerr-Conte, J;
Belaich, S;
Vandewalle, B;
Leteurtre, E;
Vantyghem, M C;
Lecomte-Houcke, M;
Proye, C;
Lefebvre, J;
Pattou, F

Publication type:

journal article

Coxsackievirus B4 can infect human pancreas ductal cells and persist in ductal-like cell cultures which results in inhibition of Pdx1 expression and disturbed formation of islet-like cell aggregates.

Published in:

Cellular & Molecular Life Sciences, 2013, v. 70, n. 21, p. 4169, doi. 10.1007/s00018-013-1383-4

By:

Sane, Famara;
Caloone, Delphine;
Gmyr, Valéry;
Engelmann, Ilka;
Belaich, Sandrine;
Kerr-Conte, Julie;
Pattou, François;
Desailloud, Rachel;
Hober, Didier

Publication type:

Article

2056-P: In Vivo Human Islet Compensation and Dysfunction to Diet-Induced Obesity: A Phase 0 Preclinical Model.

Published in:

Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2056-P

By:

KERR-CONTE, JULIE A.;
THEVENET, JULIEN;
PASQUETTI, GIANNI;
PETIT, PAULINE;
CLABAUT, CLARA;
GMYR, VALERY;
BONNER, CAROLINE;
GARGANI, SOFIA;
PATTOU, FRANCOIS

Publication type:

Article

1900-P: HNF1A Deficiency Leads to Perturbed Glucagon Secretion in Humans.

Published in:

Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1900-P

By:

SAPONARO, CHIARA;
ACOSTA-MONTALVO, ANA;
ANGUELOVA, LIA;
THEVENET, JULIEN;
CHIRAL, MAGALI;
PASQUETTI, GIANNI;
PIRON, ANTHONY;
CNOP, MIRIAM;
GMYR, VALERY;
PREHN, JOCHEN;
KERR-CONTE, JULIE A.;
PATTOU, FRANCOIS;
PONTOGLIO, MARCO;
OWEN, KATHARINE R.;
SPILIOTIS, IOANNIS;
BONNER, CAROLINE

Publication type:

Article

Interindividual Heterogeneity of SGLT2 Expression and Function in Human Pancreatic Islets.

Published in:

Diabetes, 2020, v. 69, n. 5, p. 902, doi. 10.2337/db19-0888

By:

Saponaro, Chiara;
Mühlemann, Markus;
Acosta-Montalvo, Ana;
Piron, Anthony;
Gmyr, Valery;
Delalleau, Nathalie;
Moerman, Ericka;
Thévenet, Julien;
Pasquetti, Gianni;
Coddeville, Anais;
Cnop, Miriam;
Kerr-Conte, Julie;
Staels, Bart;
Pattou, François;
Bonner, Caroline

Publication type:

Article

Islets for Research: Nothing Is Perfect, but We Can Do Better.

Published in:

2019

By:

Nano, Rita;
Kerr-Conte, Julie A.;
Bosco, Domenico;
Karlsson, Marie;
Lavallard, Vanessa;
Melzi, Raffaella;
Gmyr, Valery;
Mercalli, Alessia;
Berney, Thierry;
Pattou, François;
Korsgren, Olle;
Piemonti, Lorenzo

Publication type:

journal article

Coxsackievirus-B4 Infection Can Induce the Expression of Human Endogenous Retrovirus W in Primary Cells.

Published in:

Microorganisms, 2020, v. 8, n. 9, p. 1335, doi. 10.3390/microorganisms8091335

By:

Dechaumes, Arthur;
Bertin, Antoine;
Sane, Famara;
Levet, Sandrine;
Varghese, Jennifer;
Charvet, Benjamin;
Gmyr, Valéry;
Kerr-Conte, Julie;
Pierquin, Justine;
Arunkumar, Govindakarnavar;
Pattou, François;
Perron, Hervé;
Hober, Didier

Publication type:

Article

The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development.

Published in:

Cellular & Molecular Life Sciences, 2021, v. 78, n. 1, p. 287, doi. 10.1007/s00018-020-03499-7

By:

Tenenbaum, Mathie;
Plaisance, Valérie;
Boutry, Raphael;
Pawlowski, Valérie;
Jacovetti, Cécile;
Sanchez-Parra, Clara;
Ezanno, Hélène;
Bourry, Julien;
Beeler, Nicole;
Pasquetti, Gianni;
Gmyr, Valery;
Dalle, Stéphane;
Kerr-Conte, Julie;
Pattou, François;
Hirai, Syu-ichi;
Regazzi, Romano;
Bonnefond, Amélie;
Froguel, Philippe;
Abderrahmani, Amar

Publication type:

Article

Efficient gene delivery and silencing of mouseand human pancreatic islets.

Published in:

BMC Biotechnology, 2010, v. 10, p. 28, doi. 10.1186/1472-6750-10-28

By:

Lefebvre, Bruno;
Vandewalle, Brigitte;
Longue, Justine;
Moerman, Ericka;
Lukowiak, Bruno;
Gmyr, Valery;
Maedler, Kathrin;
Kerr-conte, Julie;
Pattou, François

Publication type:

Article