Works by Gleim, Scott

Results: 16

DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-023-44237-4

By:

Schröder, Martin;
Renatus, Martin;
Liang, Xiaoyou;
Meili, Fabian;
Zoller, Thomas;
Ferrand, Sandrine;
Gauter, Francois;
Li, Xiaoyan;
Sigoillot, Frederic;
Gleim, Scott;
Stachyra, Therese-Marie;
Thomas, Jason R.;
Begue, Damien;
Khoshouei, Maryam;
Lefeuvre, Peggy;
Andraos-Rey, Rita;
Chung, BoYee;
Ma, Renate;
Pinch, Benika;
Hofmann, Andreas

Publication type:

Article

Author Correction: DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance.

Published in:

2024

By:

Schröder, Martin;
Renatus, Martin;
Liang, Xiaoyou;
Meili, Fabian;
Zoller, Thomas;
Ferrand, Sandrine;
Gauter, Francois;
Li, Xiaoyan;
Sigoillot, Frederic;
Gleim, Scott;
Stachyra, Therese-Marie;
Thomas, Jason R.;
Begue, Damien;
Khoshouei, Maryam;
Lefeuvre, Peggy;
Andraos-Rey, Rita;
Chung, BoYee;
Ma, Renate;
Pinch, Benika;
Hofmann, Andreas

Publication type:

Correction Notice

DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-023-44237-4

By:

Schröder, Martin;
Renatus, Martin;
Liang, Xiaoyou;
Meili, Fabian;
Zoller, Thomas;
Ferrand, Sandrine;
Gauter, Francois;
Li, Xiaoyan;
Sigoillot, Frederic;
Gleim, Scott;
Stachyra, Therese-Marie;
Thomas, Jason R.;
Begue, Damien;
Khoshouei, Maryam;
Lefeuvre, Peggy;
Andraos-Rey, Rita;
Chung, BoYee;
Ma, Renate;
Pinch, Benika;
Hofmann, Andreas

Publication type:

Article

BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma.

Published in:

Blood Cancer Journal, 2022, v. 12, n. 7, p. 1, doi. 10.1038/s41408-022-00704-7

By:

Weisberg, Ellen;
Chowdhury, Basudev;
Meng, Chengcheng;
Case, Abigail E.;
Ni, Wei;
Garg, Swati;
Sattler, Martin;
Azab, Abdel Kareem;
Sun, Jennifer;
Muz, Barbara;
Sanchez, Dana;
Toure, Anthia;
Stone, Richard M.;
Galinsky, Ilene;
Winer, Eric;
Gleim, Scott;
Gkountela, Sofia;
Kedves, Alexia;
Harrington, Edmund;
Abrams, Tinya

Publication type:

Article

Recurrent ubiquitin B silencing in gynecological cancers establishes dependence on ubiquitin C.

Published in:

2017

By:

Kedves, Alexia T.;
Gleim, Scott;
Xiaoyou Liang;
Sigoillot, Frederic;
Harbinski, Fred;
Benander, Christina;
George, Elizabeth;
Jenkins, Jeremy;
Forrester, William C.;
Bonal, Dennis M.;
Gokhale, Prafulla C.;
Nguyen, Quang-De;
Kirschmeier, Paul T.;
Distel, Robert J.;
Goldberg, Michael S.;
Sanghavi, Sneha;
Liang, Xiaoyou

Publication type:

journal article

Glucose and collagen regulate human platelet activity through aldose reductase induction of thromboxane.

Published in:

2011

By:

Wai Ho Tang;
Stitham, Jeremiah;
Gleim, Scott;
Di Febbo, Concetta;
Porreca, Ettore;
Fava, Cristiano;
Tacconelli, Stefania;
Capone, Marta;
Evangelista, Virgilio;
Levantesi, Giacomo;
Li Wen;
Martin, Kathleen;
Minuz, Pietro;
Rade, Jeffrey;
Patrignani, Paola;
Hwa, John;
Tang, Wai Ho;
Wen, Li

Publication type:

journal article

DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-023-44237-4

By:

Schröder, Martin;
Renatus, Martin;
Liang, Xiaoyou;
Meili, Fabian;
Zoller, Thomas;
Ferrand, Sandrine;
Gauter, Francois;
Li, Xiaoyan;
Sigoillot, Frederic;
Gleim, Scott;
Stachyra, Therese-Marie;
Thomas, Jason R.;
Begue, Damien;
Khoshouei, Maryam;
Lefeuvre, Peggy;
Andraos-Rey, Rita;
Chung, BoYee;
Ma, Renate;
Pinch, Benika;
Hofmann, Andreas

Publication type:

Article

Multifactor dimensionality reduction analysis identifies specific nucleotide patterns promoting genetic polymorphisms.

Published in:

BioData Mining, 2009, v. 2, p. 1, doi. 10.1186/1756-0381-2-2

By:

Arehart, Eric;
Gleim, Scott;
White, Bill;
Hwa, John;
Moore, Jason H.

Publication type:

Article

Prostacyclin receptor/thromboxane receptor interactions and cellular responses in human atherothrombotic disease.

Published in:

Current Atherosclerosis Reports, 2009, v. 11, n. 3, p. 227, doi. 10.1007/s11883-009-0035-5

By:

Gleim, Scott;
Kasza, Zsolt;
Martin, Kathleen;
Hwa, John

Publication type:

Article

New Insights into Structural Determinants for Prostanoid Thromboxane A2 Receptor- and Prostacyclin Receptor-G Protein Coupling.

Published in:

Molecular & Cellular Biology, 2013, v. 33, n. 2, p. 184, doi. 10.1128/MCB.00725-12

By:

Chakraborty, Raja;
Pydi, Sai Prasad;
Gleim, Scott;
Bhullar, Rajinder Pal;
Hwa, John;
Dakshinamurti, Shyamala;
Chelikani, Prashen

Publication type:

Article

Identification of the HECT E3 ligase UBR5 as a regulator of MYC degradation using a CRISPR/Cas9 screen.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-76960-z

By:

Schukur, Lina;
Zimmermann, Tamara;
Niewoehner, Ole;
Kerr, Grainne;
Gleim, Scott;
Bauer-Probst, Beatrice;
Knapp, Britta;
Galli, Giorgio G.;
Liang, Xiaoyou;
Mendiola, Angelica;
Reece-Hoyes, John;
Rapti, Melivoia;
Barbosa, Ines;
Reschke, Markus;
Radimerski, Thomas;
Thoma, Claudio R.

Publication type:

Article

Human Thromboxane A2 Receptor Genetic Variants: In Silico, In Vitro and “In Platelet” Analysis.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067314

By:

Gleim, Scott;
Stitham, Jeremiah;
Tang, Wai Ho;
Li, Hong;
Douville, Karen;
Chelikani, Prashen;
J.Rade, Jeffrey;
Martin, Kathleen A.;
Hwa, John

Publication type:

Article

Site-Directed Mutations and the Polymorphic Variant Ala160Thr in the Human Thromboxane Receptor Uncover a Structural Role for Transmembrane Helix 4.

Published in:

PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0029996

By:

Chakraborty, Raja;
Pydi, Sai Prasad;
Gleim, Scott;
Dakshinamurti, Shyamala;
Hwa, John;
Chelikani, Prashen

Publication type:

Article

An eicosanoid-centric view of atherothrombotic risk factors.

Published in:

Cellular & Molecular Life Sciences, 2012, v. 69, n. 20, p. 3361, doi. 10.1007/s00018-012-0982-9

By:

Gleim, Scott;
Stitham, Jeremiah;
Tang, Wai;
Martin, Kathleen;
Hwa, John

Publication type:

Article

Benchmarking network algorithms for contextualizing genes of interest.

Published in:

PLoS Computational Biology, 2019, v. 15, n. 12, p. N.PAG, doi. 10.1371/journal.pcbi.1007403

By:

Hill, Abby;
Gleim, Scott;
Kiefer, Florian;
Sigoillot, Frederic;
Loureiro, Joseph;
Jenkins, Jeremy;
Morris, Melody K.

Publication type:

Article

Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition.

Published in:

Science Signaling, 2015, v. 8, n. 376, p. 1, doi. 10.1126/scisignal.2005482

By:

Yi Xie;
Yu Jin;
Gleim, Scott;
Luciano, Amelia K.;
Sessa, William C.;
Jun Yu;
Hwa, John;
Min Ding;
Martin, Kathleen A.;
Merenick, Bethany L.;
Fetalvero, Kristina M.;
Wagner, Robert J.;
Mai, Alice;
Rzucidlo, Eva M.;
Powell, Richard J.;
Tucker, David F.;
Birnbaum, Morris J.;
Ballif, Bryan A.;
Lin Hou;
Hongyu Zhao

Publication type:

Article