Works matching AU Gladyshev, Vadim N.

Results: 152

Methionine restriction and life-span control.

Published in:

Annals of the New York Academy of Sciences, 2016, v. 1363, n. 1, p. 116, doi. 10.1111/nyas.12973

By:

Lee, Byung Cheon;
Kaya, Alaattin;
Gladyshev , Vadim N.

Publication type:

Article

Biosynthesis of Selenocysteine on Its tRNA in Eukaryotes.

Published in:

PLoS Biology, 2007, v. 5, n. 1, p. 96, doi. 10.1371/journal.pbio.0050004

By:

Xue-Ming Xu;
Carlson, Bradley A.;
Mix, Heiko;
Yan Zhang;
Saira, Kazima;
Glass, Richard S.;
Berry, Marla J.;
Gladyshev, Vadim N.;
Hatfield, Dolph L.

Publication type:

Article

Different Catalytic Mechanisms in Mammalian Selenocysteine- and Cysteine-Containing Methionine-R-Sulfoxide Reductases.

Published in:

PLoS Biology, 2005, v. 3, n. 12, p. e375, doi. 10.1371/journal.pbio.0030375

By:

Kim8, Hwa-Young;
Gladyshev, Vadim N.

Publication type:

Article

Different Catalytic Mechanisms in Mammalian Selenocysteine- and Cysteine-Containing Methionine-R-Sulfoxide Reductases.

Published in:

PLoS Biology, 2005, v. 3, n. 11, p. 1, doi. 10.1371/journal.pbio.0030375

By:

Kim, Hwa-Young;
Gladyshev, Vadim N

Publication type:

Article

Development and Optimization of a Redox Enzyme-Based Fluorescence Biosensor for the Identification of MsrB1 Inhibitors.

Published in:

Antioxidants, 2024, v. 13, n. 11, p. 1348, doi. 10.3390/antiox13111348

By:

Shim, Hyun Bo;
Lee, Hyunjeong;
Cho, Hwa Yeon;
Jo, Young Ho;
Tarrago, Lionel;
Kim, Hyunggee;
Gladyshev, Vadim N.;
Lee, Byung Cheon

Publication type:

Article

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.90579

By:

Mitchell, Wayne;
Goeminne, Ludger J. E.;
Tyshkovskiy, Alexander;
Sirui Zhang;
Chen, Julie Y.;
Paulo, Joao A.;
Pierce, Kerry A.;
Choy, Angelina H.;
Clish, Clary B.;
Gygi, Steven P.;
Gladyshev, Vadim N.

Publication type:

Article

Depletion of loss-of-function germline mutations in centenarians reveals longevity genes.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52967-2

By:

Ying, Kejun;
Castro, José P.;
Shindyapina, Anastasia V.;
Tyshkovskiy, Alexander;
Moqri, Mahdi;
Goeminne, Ludger J. E.;
Milman, Sofiya;
Zhang, Zhengdong D.;
Barzilai, Nir;
Gladyshev, Vadim N.

Publication type:

Article

DNA methylation aging clocks: challenges and recommendations.

Published in:

Genome Biology, 2019, v. 20, n. 1, p. N.PAG, doi. 10.1186/s13059-019-1824-y

By:

Bell, Christopher G.;
Lowe, Robert;
Adams, Peter D.;
Baccarelli, Andrea A.;
Beck, Stephan;
Bell, Jordana T.;
Christensen, Brock C.;
Gladyshev, Vadim N.;
Heijmans, Bastiaan T.;
Horvath, Steve;
Ideker, Trey;
Issa, Jean-Pierre J.;
Kelsey, Karl T.;
Marioni, Riccardo E.;
Reik, Wolf;
Relton, Caroline L.;
Schalkwyk, Leonard C.;
Teschendorff, Andrew E.;
Wagner, Wolfgang;
Zhang, Kang

Publication type:

Article

Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation.

Published in:

PLoS Genetics, 2019, v. 15, n. 2, p. 1, doi. 10.1371/journal.pgen.1007917

By:

O’Connell, Amy E.;
Gerashchenko, Maxim V.;
O’Donohue, Marie-Francoise;
Rosen, Samantha M.;
Huntzinger, Eric;
Gleeson, Diane;
Galli, Antonella;
Ryder, Edward;
Cao, Siqi;
Murphy, Quinn;
Kazerounian, Shideh;
Morton, Sarah U.;
Schmitz-Abe, Klaus;
Gladyshev, Vadim N.;
Gleizes, Pierre-Emmanuel;
Séraphin, Bertrand;
Agrawal, Pankaj B.

Publication type:

Article

AgeMeta: Quantitative Gene Expression Database of Mammalian Aging.

Published in:

Biochemistry (00062979), 2024, v. 89, n. 2, p. 313, doi. 10.1134/S000629792402010X

By:

Tikhonov, Stanislav;
Batin, Mikhail;
Gladyshev, Vadim N.;
Dmitriev, Sergey E.;
Tyshkovskiy, Alexander

Publication type:

Article

Insights into the Chemical Biology of Selenium.

Published in:

Phosphorus, Sulfur & Silicon & the Related Elements, 2008, v. 183, n. 4, p. 924, doi. 10.1080/10426500801898366

By:

Glass, Richard S.;
Berry, Marla J.;
Block, Eric;
Boakye, Harriet T.;
Carlson, Bradley A.;
Gailer, Jüurgen;
George, Graham N.;
Gladyshev, Vadim N.;
Hatfield, Dolph L.;
Jacobsen, Neil E.;
Johnson, Sherida;
Kahakachchi, Chethaka;
Kamiński, Rafal;
Manley, Shawn A.;
Mix, Heiko;
Pickering, Ingrid J.;
Prenner, Elmar J.;
Saira, Kazima;
Skowrońska, Aleksandra;
Tyson, Julian F.

Publication type:

Article

Recode-2: new design, new search tools, and many more genes.

Published in:

Nucleic Acids Research, 2010, v. 38, p. D69, doi. 10.1093/nar/gkp788

By:

Bekaert, Michaël;
Firth, Andrew E.;
Yan Zhang;
Gladyshev, Vadim N.;
Atkins, John F.;
Baranov, Pavel V.

Publication type:

Article

Functional characterization of alternatively spliced human SECISBP2 transcript variants.

Published in:

Nucleic Acids Research, 2008, v. 36, n. 22, p. 7192, doi. 10.1093/nar/gkn829

By:

Papp, Laura V.;
Wang, Junning;
Kennedy, Derek;
Boucher, Didier;
Zhang, Yan;
Gladyshev, Vadim N.;
Singh, Ravindra N.;
Khanna, Kum Kum

Publication type:

Article

SelenoDB 1.0 : a database of selenoprotein genes, proteins and SECIS elements.

Published in:

Nucleic Acids Research, 2008, v. 36, p. D332, doi. 10.1093/nar/gkm731

By:

Castellano, Sergi;
Gladyshev, Vadim N.;
Guigó, Roderic;
Berry, Marla J.

Publication type:

Article

High content of proteins containing 21st and 22nd amino acids, selenocysteine and pyrrolysine, in a symbiotic deltaproteobacterium of gutless worm Olavius algarvensis.

Published in:

Nucleic Acids Research, 2007, v. 35, n. 15, p. 4952, doi. 10.1093/nar/gkm514

By:

Zhang, Yan;
Gladyshev, Vadim N.

Publication type:

Article

SECIS elements in the coding regions of selenoprotein transcripts are functional in higher eukaryotes.

Published in:

Nucleic Acids Research, 2007, v. 35, n. 2, p. 414, doi. 10.1093/nar/gkl1060

By:

Mix, Heiko;
Lobanov, Alexey V.;
Gladyshev, Vadim N.

Publication type:

Article

Selenium metabolism in Trypanosoma: characterization of selenoproteomes and identification of a Kinetoplastida-specific selenoprotein.

Published in:

Nucleic Acids Research, 2006, v. 34, n. 14, p. 4012, doi. 10.1093/nar/gkl541

By:

Lobanov, Alexey V.;
Gromer, Stephan;
Salinas, Gustavo;
Gladyshev, Vadim N.

Publication type:

Article

The Plasmodium selenoproteome.

Published in:

Nucleic Acids Research, 2006, v. 34, n. 2, p. 496, doi. 10.1093/nar/gkj450

By:

Lobanov, Alexey V.;
Delgado, Cesar;
Rahlfs, Stefan;
Novoselov, Sergey V.;
Kryukov, Gregory V.;
Gromer, Stephan;
Hatfield, Dolph L.;
Becker, Katja;
Gladyshev, Vadim N.

Publication type:

Article

Selenocysteine insertion directed by the 3′-UTR SECIS element in Escherichia coli.

Published in:

Nucleic Acids Research, 2005, v. 33, n. 8, p. 2486

By:

Su, Dan;
Li, Yehua;
Gladyshev, Vadim N.

Publication type:

Article

Nematode selenoproteome: the use of the selenocysteine insertion system to decode one codon in an animal genome?

Published in:

Nucleic Acids Research, 2005, v. 33, n. 7, p. 2227, doi. 10.1093/nar/gki507

By:

Taskov, Kalin;
Chapple, Charles;
Kryukov, Gregory V.;
Castellano, Sergi;
Lobanov, Alexey V.;
Korotkov, Konstantin V.;
Guigó, Roderic;
Gladyshev, Vadim N.

Publication type:

Article

Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28385-7

By:

Kang, Donghyun;
Lee, Jeeyeon;
Jung, Jisu;
Carlson, Bradley A.;
Chang, Moon Jong;
Chang, Chong Bum;
Kang, Seung-Baik;
Lee, Byung Cheon;
Gladyshev, Vadim N.;
Hatfield, Dolph L.;
Lee, Byeong Jae;
Kim, Jin-Hong

Publication type:

Article

Epigenetic aging of the demographically non-aging naked mole-rat.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-27959-9

By:

Kerepesi, Csaba;
Meer, Margarita V.;
Ablaeva, Julia;
Amoroso, Vince G.;
Lee, Sang-Goo;
Zhang, Bohan;
Gerashchenko, Maxim V.;
Trapp, Alexandre;
Yim, Sun Hee;
Lu, Ake T.;
Levine, Morgan E.;
Seluanov, Andrei;
Horvath, Steve;
Park, Thomas J.;
Gorbunova, Vera;
Gladyshev, Vadim N.

Publication type:

Article

Evolution of selenocysteine-containing proteins: Significance of identification and functional characterization of selenoproteins.

Published in:

Biofactors, 2001, v. 14, n. 1-4, p. 87, doi. 10.1002/biof.5520140112

By:

Gladyshev, Vadim N.;
Kryukov, Gregory V.

Publication type:

Article

Thioredoxin and peptide methionine sulfoxide reductase: Convergence of similar structure and function in distinct structural folds.

Published in:

Proteins, 2002, v. 46, n. 2, p. 149, doi. 10.1002/prot.10003

By:

Gladyshev, Vadim N.

Publication type:

Article

Lifespan Extension Conferred by Endoplasmic Reticulum Secretory Pathway Deficiency Requires Induction of the Unfolded Protein Response.

Published in:

PLoS Genetics, 2014, v. 10, n. 1, p. 1, doi. 10.1371/journal.pgen.1004019

By:

Labunskyy, Vyacheslav M.;
Gerashchenko, Maxim V.;
Delaney, Joe R.;
Kaya, Alaattin;
Kennedy, Brian K.;
Kaeberlein, Matt;
Gladyshev, Vadim N.

Publication type:

Article

Trends in Selenium Utilization in Marine Microbial World Revealed through the Analysis of the Global Ocean Sampling (GOS) Project.

Published in:

PLoS Genetics, 2008, v. 4, n. 6, p. 1, doi. 10.1371/journal.pgen.1000095

By:

Yan Zhang;
Gladyshev, Vadim N.

Publication type:

Article

MICAL1 constrains cardiac stress responses and protects against disease by oxidizing CaMKII.

Published in:

2020

By:

Konstantinidis, Klitos;
Bezzerides, Vassilios J.;
Lo Lai;
Isbell, Holly M.;
An-Chi Wei;
Yuejin Wu;
Viswanathan, Meera C.;
Blum, Ian D.;
Granger, Jonathan M.;
Heims-Waldron, Danielle;
Donghui Zhang;
Luczak, Elizabeth D.;
Murphy, Kevin R.;
Fujian Lu;
Gratz, Daniel H.;
Manta, Bruno;
Qiang Wang;
Qinchuan Wang;
Kolodkin, Alex L.;
Gladyshev, Vadim N.

Publication type:

journal article

Comparative time-series multi-omics analyses suggest H1.2 involvement in anoxic adaptation and cancer resistance.

Published in:

PLoS Biology, 2024, v. 22, n. 8, p. 1, doi. 10.1371/journal.pbio.3002778

By:

Du, Juan;
Liu, Weiqiang;
Li, Meng;
Li, Zihao;
Li, Xuanjing;
Dai, Yichen;
Liu, Gaoming;
Wang, Xiao;
Zhu, Pingfen;
Gladyshev, Vadim N.;
Zhou, Xuming

Publication type:

Article

An algorithm for identification of bacterial selenocysteine insertion sequence elements and selenoprotein genes.

Published in:

Bioinformatics, 2005, v. 21, n. 11, p. 2580

By:

Vadim N. Gladyshev

Publication type:

Article

A single cell atlas of the mouse seminal vesicle Open Access.

Published in:

G3: Genes | Genomes | Genetics, 2025, v. 15, n. 5, p. 1, doi. 10.1093/g3journal/jkaf045

By:

Sun, Fengyun;
Desevin, Kathleen;
Fu, Yu;
Parameswaran, Shanmathi;
Mayall, Jemma;
Rinaldi, Vera;
Krietenstein, Nils;
Manukyan, Artür;
Yin, Qiangzong;
Galan, Carolina;
Yang, Chih-Hsiang;
Shindyapina, Anastasia V;
Gladyshev, Vadim N;
Garber, Manuel;
Schjenken, John E;
Rando, Oliver J

Publication type:

Article

A Chromosome-Level Genome of the Agile Gracile Mouse Opossum (Gracilinanus agilis).

Published in:

Genome Biology & Evolution, 2021, v. 13, n. 8, p. 1, doi. 10.1093/gbe/evab162

By:

Tian, Ran;
Han, Kai;
Geng, Yuepan;
Yang, Chen;
Guo, Han;
Shi, Chengcheng;
Xu, Shixia;
Yang, Guang;
Zhou, Xuming;
Gladyshev, Vadim N;
Liu, Xin;
Chopin, Lisa K;
Fisher, Diana O;
Baker, Andrew M;
Leiner, Natália O;
Fan, Guangyi;
Seim, Inge

Publication type:

Article

Molecular Footprints of Aquatic Adaptation Including Bone Mass Changes in Cetaceans.

Published in:

Genome Biology & Evolution, 2018, v. 10, n. 3, p. 967, doi. 10.1093/gbe/evy062

By:

Xuming Zhou;
Di Sun;
Xuanmin Guang;
Siming Ma;
Xiaodong Fang;
Mariotti, Marco;
Nielsen, Rasmus;
Gladyshev, Vadim N.;
Guang Yang

Publication type:

Article

Historical Roles of Selenium and Selenoproteins in Health and Development: The Good, the Bad and the Ugly.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 5, doi. 10.3390/ijms23010005

By:

Tsuji, Petra A.;
Santesmasses, Didac;
Lee, Byeong J.;
Gladyshev, Vadim N.;
Hatfield, Dolph L.

Publication type:

Article

Identification of Signaling Pathways for Early Embryonic Lethality and Developmental Retardation in Sephs1 −/− Mice.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 11647, doi. 10.3390/ijms222111647

By:

Bang, Jeyoung;
Han, Minguk;
Yoo, Tack-Jin;
Qiao, Lu;
Jung, Jisu;
Na, Jiwoon;
Carlson, Bradley A.;
Gladyshev, Vadim N.;
Hatfield, Dolph L.;
Kim, Jin-Hong;
Kim, Lark Kyun;
Lee, Byeong Jae

Publication type:

Article

Pathogenic Variants in Selenoproteins and Selenocysteine Biosynthesis Machinery.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 11593, doi. 10.3390/ijms222111593

By:

Santesmasses, Didac;
Gladyshev, Vadim N.

Publication type:

Article

Selenium and the 15kDa Selenoprotein Impact Colorectal Tumorigenesis by Modulating Intestinal Barrier Integrity.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10651, doi. 10.3390/ijms221910651

By:

Canter, Jessica A.;
Ernst, Sarah E.;
Peters, Kristin M.;
Carlson, Bradley A.;
Thielman, Noelle R. J.;
Grysczyk, Lara;
Udofe, Precious;
Yu, Yunkai;
Cao, Liang;
Davis, Cindy D.;
Gladyshev, Vadim N.;
Hatfield, Dolph L.;
Tsuji, Petra A.

Publication type:

Article

svist4get: a simple visualization tool for genomic tracks from sequencing experiments.

Published in:

BMC Bioinformatics, 2019, v. 20, n. 1, p. 1, doi. 10.1186/s12859-019-2706-8

By:

Egorov, Artyom A.;
Sakharova, Ekaterina A.;
Anisimova, Aleksandra S.;
Dmitriev, Sergey E.;
Gladyshev, Vadim N.;
Kulakovskiy, Ivan V.

Publication type:

Article

Thioredoxin reductase 1 deficiency enhances selenite toxicity in cancer cells via a thioredoxin-independent mechanism.

Published in:

Biochemical Journal, 2012, v. 446, n. 1, p. 423, doi. 10.1042/BJ20120618

By:

TOBE, Ryuta;
Min-Hyuk YOO;
FRADEJAS, Noelia;
CARLSON, Bradley A.;
CALVO, Soledad;
GLADYSHEV, Vadim N.;
HATFIELD, Dolph L.

Publication type:

Article

Thioredoxin reductase 1 deficiency enhances selenite toxicity in cancer cells via a thioredoxin-independent mechanism.

Published in:

Biochemical Journal, 2012, v. 445, n. 3, p. 423, doi. 10.1042/BJ20120618

By:

TOBE, Ryuta;
YOO, Min-Hyuk;
FRADEJAS, Noelia;
CARLSON, Bradley A.;
CALVO, Soledad;
GLADYSHEV, Vadim N.;
HATFIELD, Dolph L.

Publication type:

Article

The prokaryotic selenoproteome.

Published in:

EMBO Reports, 2004, v. 5, n. 5, p. 538, doi. 10.1038/sj.embor.7400126

By:

Kryukov, Gregory V.;
Gladyshev, Vadim N.

Publication type:

Article

Reconsidering the evolution of eukaryotic selenoproteins: a novel nonmammalian family with scattered phylogenetic distribution.

Published in:

EMBO Reports, 2004, v. 5, n. 1, p. 71, doi. 10.1038/sj.embor.7400036

By:

Castellano, Sergi;
Novoselov, Seigey V.;
Kryukov, Gregory V.;
Lescure, Alain;
Blanco, Enrique;
Krol, Alain;
Gladyshev, Vadim N.;
Guigó, Roderic

Publication type:

Article

How can aging be reversed? Exploring rejuvenation from a damage‐based perspective.

Published in:

Advanced Genetics, 2020, v. 1, n. 1, p. 1, doi. 10.1002/ggn2.10025

By:

Zhang, Bohan;
Gladyshev, Vadim N.

Publication type:

Article

Comparative genetics of longevity and cancer: insights from long-lived rodents.

Published in:

Nature Reviews Genetics, 2014, v. 15, n. 8, p. 531, doi. 10.1038/nrg3728

By:

Gorbunova, Vera;
Seluanov, Andrei;
Zhang, Zhengdong;
Gladyshev, Vadim N.;
Vijg, Jan

Publication type:

Article

Evolution of natural lifespan variation and molecular strategies of extended lifespan in yeast.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.64860

By:

Kaya, Alaattin;
Zi Jin Phua, Cheryl;
Lee, Mitchell;
Lu Wang;
Tyshkovskiy, Alexander;
Siming Ma;
Barre, Benjamin;
Weiqiang Liu;
Harrison, Benjamin R.;
Xiaqing Zhao;
Xuming Zhou;
Wasko, Brian M.;
Bammler, Theo K.;
EL Promislow, Daniel;
Kaeberlein, Matt;
Gladyshev, Vadim N.

Publication type:

Article

High‐throughput profiling reveals perturbation of endoplasmic reticulum stress‐related genes in atherosclerosis induced by high‐cholesterol diet and the protective role of vitamin E.

Published in:

Biofactors, 2020, v. 46, n. 4, p. 653, doi. 10.1002/biof.1635

By:

Bozaykut, Perinur;
Ekren, Ruchan;
Sezerman, Osman Ugur;
Gladyshev, Vadim N.;
Ozer, Nesrin Kartal

Publication type:

Article

Selenoproteinless animals: Selenophosphate synthetase SPS1 functions in a pathway unrelated to selenocysteine biosynthesis.

Published in:

Protein Science: A Publication of the Protein Society, 2008, v. 17, n. 1, p. 176, doi. 10.1110/ps.073261508

By:

Lobanov, Alexey V.;
Hatfield, Dolph L.;
Gladyshev, Vadim N.

Publication type:

Article

Non-animal origin of animal thioredoxin reductases: Implications for selenocysteine evolution and evolution of protein function through carboxy-terminal extensions.

Published in:

Protein Science: A Publication of the Protein Society, 2003, v. 12, n. 2, p. 372, doi. 10.1110/ps.0226503

By:

Novoselov, Sergey V.;
Gladyshev, Vadim N.

Publication type:

Article

CxxS: Fold-independent redox motif revealed by genome-wide searches for thiol/disulfide oxidoreductase function.

Published in:

Protein Science: A Publication of the Protein Society, 2002, v. 11, n. 10, p. 2285, doi. 10.1110/ps.0218302

By:

Fomenko, Dmitri E.;
Gladyshev, Vadim N.

Publication type:

Article

Large‐scale across species transcriptomic analysis identifies genetic selection signatures associated with longevity in mammals.

Published in:

EMBO Journal, 2023, v. 42, n. 17, p. 1, doi. 10.15252/embj.2022112740

By:

Liu, Weiqiang;
Zhu, Pingfen;
Li, Meng;
Li, Zihao;
Yu, Yang;
Liu, Gaoming;
Du, Juan;
Wang, Xiao;
Yang, Jing;
Tian, Ran;
Seim, Inge;
Kaya, Alaattin;
Li, Mingzhou;
Li, Ming;
Gladyshev, Vadim N;
Zhou, Xuming

Publication type:

Article

Characterization of naked mole‐rat hematopoiesis reveals unique stem and progenitor cell patterns and neotenic traits.

Published in:

EMBO Journal, 2022, v. 41, n. 15, p. 1, doi. 10.15252/embj.2021109694

By:

Emmrich, Stephan;
Trapp, Alexandre;
Tolibzoda Zakusilo, Frances;
Straight, Maggie E;
Ying, Albert K;
Tyshkovskiy, Alexander;
Mariotti, Marco;
Gray, Spencer;
Zhang, Zhihui;
Drage, Michael G;
Takasugi, Masaki;
Klusmann, Jan‐Henning;
Gladyshev, Vadim N;
Seluanov, Andrei;
Gorbunova, Vera

Publication type:

Article