Works by Giorgis, Marta

Results: 15

Dihydroorotate dehydrogenase inhibition reveals metabolic vulnerability in chronic myeloid leukemia.

Published in:

Cell Death & Disease, 2022, v. 13, n. 6, p. 1, doi. 10.1038/s41419-022-05028-9

By:

Houshmand, Mohammad;
Vitale, Nicoletta;
Orso, Francesca;
Cignetti, Alessandro;
Molineris, Ivan;
Gaidano, Valentina;
Sainas, Stefano;
Giorgis, Marta;
Boschi, Donatella;
Fava, Carmen;
Passoni, Alice;
Gai, Marta;
Geuna, Massimo;
Sora, Federica;
Iurlo, Alessandra;
Abruzzese, Elisabetta;
Breccia, Massimo;
Mulas, Olga;
Caocci, Giovanni;
Castagnetti, Fausto

Publication type:

Article

α-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasis.

Published in:

Cell Death & Disease, 2018, v. 9, n. 7, p. 1, doi. 10.1038/s41419-018-0802-8

By:

Atlante, Sandra;
Visintin, Alessia;
Marini, Elisabetta;
Savoia, Matteo;
Dianzani, Chiara;
Giorgis, Marta;
Sürün, Duran;
Maione, Federica;
Schnütgen, Frank;
Farsetti, Antonella;
Zeiher, Andreas M.;
Bertinaria, Massimo;
Giraudo, Enrico;
Spallotta, Francesco;
Cencioni, Chiara;
Gaetano, Carlo

Publication type:

Article

Design and synthesis of N-benzoyl amino acid derivatives as DNA methylation inhibitors.

Published in:

Chemical Biology & Drug Design, 2016, v. 88, n. 5, p. 664, doi. 10.1111/cbdd.12794

By:

Garella, Davide;
Atlante, Sandra;
Borretto, Emily;
Cocco, Mattia;
Giorgis, Marta;
Costale, Annalisa;
Stevanato, Livio;
Miglio, Gianluca;
Cencioni, Chiara;
Fernández ‐ de Gortari, Eli;
Medina ‐ Franco, José L.;
Spallotta, Francesco;
Gaetano, Carlo;
Bertinaria, Massimo

Publication type:

Article

The role of fluorine in stabilizing the bioactive conformation of dihydroorotate dehydrogenase inhibitors.

Published in:

Journal of Molecular Modeling, 2013, v. 19, n. 3, p. 1099, doi. 10.1007/s00894-012-1643-5

By:

Bonomo, Silvia;
Tosco, Paolo;
Giorgis, Marta;
Lolli, Marco;
Fruttero, Roberta

Publication type:

Article

The Synergism between DHODH Inhibitors and Dipyridamole Leads to Metabolic Lethality in Acute Myeloid Leukemia.

Published in:

Cancers, 2021, v. 13, n. 5, p. 1003, doi. 10.3390/cancers13051003

By:

Gaidano, Valentina;
Houshmand, Mohammad;
Vitale, Nicoletta;
Carrà, Giovanna;
Morotti, Alessandro;
Tenace, Valerio;
Rapelli, Stefania;
Sainas, Stefano;
Pippione, Agnese Chiara;
Giorgis, Marta;
Boschi, Donatella;
Lolli, Marco Lucio;
Cilloni, Daniela;
Cignetti, Alessandro;
Saglio, Giuseppe;
Circosta, Paola;
Wong, David

Publication type:

Article

Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAF V600E Protein.

Published in:

Molecules, 2022, v. 27, n. 23, p. 8513, doi. 10.3390/molecules27238513

By:

Marini, Elisabetta;
Marino, Marco;
Gionfriddo, Giulia;
Maione, Federica;
Pandini, Marta;
Oddo, Daniele;
Giorgis, Marta;
Rolando, Barbara;
Blua, Federica;
Gastaldi, Simone;
Marchiò, Serena;
Kovachka, Sandra;
Spyrakis, Francesca;
Gianquinto, Eleonora;
Di Nicolantonio, Federica;
Bertinaria, Massimo

Publication type:

Article

Identification of Human Dihydroorotate Dehydrogenase Inhibitor by a Pharmacophore-Based Virtual Screening Study.

Published in:

Molecules, 2022, v. 27, n. 12, p. 3660, doi. 10.3390/molecules27123660

By:

Galati, Salvatore;
Sainas, Stefano;
Giorgis, Marta;
Boschi, Donatella;
Lolli, Marco L.;
Ortore, Gabriella;
Poli, Giulio;
Tuccinardi, Tiziano

Publication type:

Article

Chemical Modulation of the 1-(Piperidin-4-yl)-1,3-dihydro-2 H -benzo[d]imidazole-2-one Scaffold as a Novel NLRP3 Inhibitor.

Published in:

Molecules, 2021, v. 26, n. 13, p. 3975, doi. 10.3390/molecules26133975

By:

Gastaldi, Simone;
Boscaro, Valentina;
Gianquinto, Eleonora;
Sandall, Christina F.;
Giorgis, Marta;
Marini, Elisabetta;
Blua, Federica;
Gallicchio, Margherita;
Spyrakis, Francesca;
MacDonald, Justin A.;
Bertinaria, Massimo

Publication type:

Article

An evaluation of the antioxidant properties of Arthrospira maxima extracts obtained using non-conventional techniques.

Published in:

European Food Research & Technology, 2017, v. 243, n. 2, p. 227, doi. 10.1007/s00217-016-2738-5

By:

Giorgis, Marta;
Garella, Davide;
Cena, Clara;
Boffa, Luisa;
Cravotto, Giancarlo;
Marini, Elisabetta

Publication type:

Article

Chemical modifications of Tonda Gentile Trilobata hazelnut and derived processing products under different infrared and hot‐air roasting conditions: a combined analytical study.

Published in:

Journal of the Science of Food & Agriculture, 2018, v. 98, n. 12, p. 4561, doi. 10.1002/jsfa.8984

By:

Binello, Arianna;
Giorgis, Marta;
Cena, Clara;
Cravotto, Giancarlo;
Rotolo, Laura;
Oliveri, Paolo;
Malegori, Cristina;
Casale, Monica;
Cavallero, Maria Chiara;
Buso, Stefania

Publication type:

Article

The effect of hazelnut roasted skin from different cultivars on the quality attributes, polyphenol content and texture of fresh egg pasta.

Published in:

Journal of the Science of Food & Agriculture, 2015, v. 95, n. 8, p. 1678, doi. 10.1002/jsfa.6871

By:

Zeppa, Giuseppe;
Belviso, Simona;
Bertolino, Marta;
Cavallero, Maria Chiara;
Dal Bello, Barbara;
Ghirardello, Daniela;
Giordano, Manuela;
Giorgis, Marta;
Grosso, Arianna;
Rolle, Luca;
Gerbi, Vincenzo

Publication type:

Article

The effect of hazelnut roasted skin from different cultivars on the quality attributes, polyphenol content and texture of fresh egg pasta.

Published in:

Journal of the Science of Food & Agriculture, 2015, v. 95, n. 8, p. 1678, doi. 10.1002/jsfa.6871

By:

Zeppa, Giuseppe;
Belviso, Simona;
Bertolino, Marta;
Cavallero, Maria Chiara;
Dal Bello, Barbara;
Ghirardello, Daniela;
Giordano, Manuela;
Giorgis, Marta;
Grosso, Arianna;
Rolle, Luca;
Gerbi, Vincenzo

Publication type:

Article

Methotrexate-Loaded Solid Lipid Nanoparticles: Protein Functionalization to Improve Brain Biodistribution.

Published in:

Pharmaceutics, 2019, v. 11, n. 2, p. 65, doi. 10.3390/pharmaceutics11020065

By:

Muntoni, Elisabetta;
Martina, Katia;
Marini, Elisabetta;
Giorgis, Marta;
Lazzarato, Loretta;
Salaroglio, Iris Chiara;
Riganti, Chiara;
Lanotte, Michele;
Battaglia, Luigi

Publication type:

Article

Design, Synthesis, and Evaluation of Acrylamide Derivatives as Direct NLRP3 Inflammasome Inhibitors.

Published in:

ChemMedChem, 2016, v. 11, n. 16, p. 1790, doi. 10.1002/cmdc.201600055

By:

Cocco, Mattia;
Miglio, Gianluca;
Giorgis, Marta;
Garella, Davide;
Marini, Elisabetta;
Costale, Annalisa;
Regazzoni, Luca;
Vistoli, Giulio;
Orioli, Marica;
Massulaha‐Ahmed, Raïhane;
Détraz‐Durieux, Isabelle;
Groslambert, Marine;
Py, Bénédicte F.;
Bertinaria, Massimo

Publication type:

Article

Multitarget Drugs: Synthesis and Preliminary Pharmacological Characterization of Zileuton Analogues Endowed with Dual 5-LO Inhibitor and NO-Dependent Activities.

Published in:

ChemMedChem, 2010, v. 5, n. 9, p. 1444, doi. 10.1002/cmdc.201000198

By:

Boschi, Donatella;
Giorgis, Marta;
Cena, Clara;
Talniya, Naveen Chandra;
Di Stilo, Antonella;
Morini, Giuseppina;
Coruzzi, Gabriella;
Guaita, Elena;
Fruttero, Roberta;
Gasco, Alberto

Publication type:

Article