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Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease.
- Published in:
- eLife, 2024, p. 1, doi. 10.7554/eLife.89889
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- Publication type:
- Article
Synthesis and Characterization of Click Chemical Probes for Single-Cell Resolution Detection of Epichaperomes in Neurodegenerative Disorders.
- Published in:
- Biomedicines, 2024, v. 12, n. 6, p. 1252, doi. 10.3390/biomedicines12061252
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- Publication type:
- Article
Overexpression of pathogenic tau in astrocytes causes a reduction in AQP4 and GLT1, an immunosuppressed phenotype and unique transcriptional responses to repetitive mild TBI without appreciable changes in tauopathy.
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- Journal of Neuroinflammation, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12974-024-03117-4
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- Article
Apolipoprotein E2 Expression Alters Endosomal Pathways in a Mouse Model With Increased Brain Exosome Levels During Aging.
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- Traffic, 2024, v. 25, n. 5, p. 1, doi. 10.1111/tra.12937
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- Publication type:
- Article
Down Syndrome Biobank Consortium: A perspective.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 3, p. 2262, doi. 10.1002/alz.13692
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- Publication type:
- Article
Micro-RNA profiles of pathology and resilience in posterior cingulate cortex of cognitively intact elders.
- Published in:
- Brain Communications, 2024, v. 6, n. 2, p. 1, doi. 10.1093/braincomms/fcae082
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- Article
Dentate Gyrus Granule Cells Show Stability of BDNF Protein Expression in Mossy Fiber Axons with Age, and Resistance to Alzheimer's Disease Neuropathology in a Mouse Model.
- Published in:
- eNeuro, 2024, v. 11, n. 3, p. 1, doi. 10.1523/ENEURO.0192-23.2023
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- Article
Application of robust regression in translational neuroscience studies with non-Gaussian outcome data.
- Published in:
- Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2023.1299451
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- Article
Posterior cingulate cortex microRNA alterations in cognitive resilience, mild cognitive impairment, and Alzheimer's disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079260
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- Article
Posterior cingulate cortex microRNA alterations in cognitive resilience, mild cognitive impairment, and Alzheimer's disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079260
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- Article
Basal forebrain cholinergic neurons are vulnerable in a mouse model of Down syndrome and their molecular fingerprint is rescued by maternal choline supplementation.
- Published in:
- FASEB Journal, 2023, v. 37, n. 6, p. 1, doi. 10.1096/fj.202202111RR
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- Article
Editorial: Hippocampal mechanisms in aging and clinical memory decline.
- Published in:
- Frontiers in Aging Neuroscience, 2023, p. 01, doi. 10.3389/fnagi.2023.1204954
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- Publication type:
- Article
Microisolation of Spatially Characterized Single Populations of Neurons for RNA Sequencing from Mouse and Postmortem Human Brain Tissues.
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- Journal of Clinical Medicine, 2023, v. 12, n. 9, p. 3304, doi. 10.3390/jcm12093304
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- Publication type:
- Article
Co-expression network analysis of frontal cortex during the progression of Alzheimer's disease.
- Published in:
- Cerebral Cortex, 2022, v. 32, n. 22, p. 5108, doi. 10.1093/cercor/bhac001
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- Article
Posterior cingulate cortex reveals an expression profile of resilience in cognitively intact elders.
- Published in:
- Brain Communications, 2022, v. 4, n. 4, p. 1, doi. 10.1093/braincomms/fcac162
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- Article
Comparative analysis of transcriptome remodeling in plaque-associated and plaque-distant microglia during amyloid-β pathology progression in mice.
- Published in:
- 2022
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- Publication type:
- journal article
Associations Between DNA Methylation Age Acceleration, Depressive Symptoms, and Cardiometabolic Traits in African American Mothers From the InterGEN Study.
- Published in:
- Epigenetics Insights, 2022, p. 1, doi. 10.1177/25168657221109781
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- Publication type:
- Article
Loss of glucocorticoid receptor phosphorylation contributes to cognitive and neurocentric damages of the amyloid-β pathway.
- Published in:
- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01396-7
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- Article
Disease‐specific interactome alterations via epichaperomics: the case for Alzheimer's disease.
- Published in:
- FEBS Journal, 2022, v. 289, n. 8, p. 2047, doi. 10.1111/febs.16031
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- Article
Correction to: Profiling Basal Forebrain Cholinergic Neurons Reveals a Molecular Basis for Vulnerability Within the Ts65Dn Model of Down Syndrome and Alzheimer's Disease.
- Published in:
- 2022
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- Publication type:
- Correction Notice
Associations Between DNA Methylation Age Acceleration, Depressive Symptoms, and Cardiometabolic Traits in African American Mothers From the InterGEN Study.
- Published in:
- Epigenetics Insights, 2022, v. 15, p. 1, doi. 10.1177/25168657221109781
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- Publication type:
- Article
The penalty of stress ‐ Epichaperomes negatively reshaping the brain in neurodegenerative disorders.
- Published in:
- Journal of Neurochemistry, 2021, v. 159, n. 6, p. 958, doi. 10.1111/jnc.15525
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- Article
Editorial: Down Syndrome, Neurodegeneration and Dementia.
- Published in:
- Frontiers in Aging Neuroscience, 2021, p. 1, doi. 10.3389/fnagi.2021.791044
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- Article
Maternal Choline Supplementation as a Potential Therapy for Down Syndrome: Assessment of Effects Throughout the Lifespan.
- Published in:
- Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.723046
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- Publication type:
- Article
Profiling Basal Forebrain Cholinergic Neurons Reveals a Molecular Basis for Vulnerability Within the Ts65Dn Model of Down Syndrome and Alzheimer's Disease.
- Published in:
- Molecular Neurobiology, 2021, v. 58, n. 10, p. 5141, doi. 10.1007/s12035-021-02453-3
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- Article
Oxidative Phosphorylation Is Dysregulated Within the Basocortical Circuit in a 6-month old Mouse Model of Down Syndrome and Alzheimer's Disease.
- Published in:
- Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.707950
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- Publication type:
- Article
Adiponectin Modulation by Genotype and Maternal Choline Supplementation in a Mouse Model of Down Syndrome and Alzheimer's Disease.
- Published in:
- Journal of Clinical Medicine, 2021, v. 10, n. 13, p. 2994, doi. 10.3390/jcm10132994
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- Publication type:
- Article
Expression profiling of precuneus layer III cathepsin D‐immunopositive pyramidal neurons in mild cognitive impairment and Alzheimer's disease: Evidence for neuronal signaling vulnerability.
- Published in:
- Journal of Comparative Neurology, 2020, v. 528, n. 16, p. 2748, doi. 10.1002/cne.24929
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- Article
Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease.
- Published in:
- 2020
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- Publication type:
- journal article
Calorie restriction slows age-related microbiota changes in an Alzheimer's disease model in female mice.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-54187-x
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- Publication type:
- Article
Long-term effects of maternal choline supplementation on CA1 pyramidal neuron gene expression in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.
- Published in:
- FASEB Journal, 2019, v. 33, n. 9, p. 9871, doi. 10.1096/fj.201802669RR
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- Publication type:
- Article
P3‐173: MICROARRAY ANALYSES REVEAL SENESCENCE‐ASSOCIATED GENE EXPRESSION IN ALZHEIMER'S DISEASE AND TRANSGENIC MOUSE MODELS WITH AMYLOID DEPOSITION OR TAUOPATHY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P996, doi. 10.1016/j.jalz.2019.06.3202
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- Publication type:
- Article
Maternal Choline Supplementation Alters Basal Forebrain Cholinergic Neuron Gene Expression in the Ts65Dn Mouse Model of Down Syndrome.
- Published in:
- Developmental Neurobiology (19328451), 2019, v. 79, n. 7, p. 664, doi. 10.1002/dneu.22700
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- Article
Nerve Growth Factor Pathobiology During the Progression of Alzheimer's Disease.
- Published in:
- Frontiers in Neuroscience, 2019, p. 1, doi. 10.3389/fnins.2019.00533
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- Publication type:
- Article
Selective decline of neurotrophin and neurotrophin receptor genes within CA1 pyramidal neurons and hippocampus proper: Correlation with cognitive performance and neuropathology in mild cognitive impairment and Alzheimer's disease.
- Published in:
- Hippocampus, 2019, v. 29, n. 5, p. 422, doi. 10.1002/hipo.22802
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- Article
Frontal cortex and striatal cellular and molecular pathobiology in individuals with Down syndrome with and without dementia.
- Published in:
- Acta Neuropathologica, 2019, v. 137, n. 3, p. 413, doi. 10.1007/s00401-019-01965-6
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- Publication type:
- Article
Apolipoprotein E4 genotype compromises brain exosome production.
- Published in:
- 2019
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- Publication type:
- journal article
CA1 pyramidal neuron gene expression mosaics in the Ts65Dn murine model of Down syndrome and Alzheimer's disease following maternal choline supplementation.
- Published in:
- Hippocampus, 2018, v. 28, n. 4, p. 251, doi. 10.1002/hipo.22832
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- Publication type:
- Article
The Stress-Induced Transcription Factor NR4A1 Adjusts Mitochondrial Function and Synapse Number in Prefrontal Cortex.
- Published in:
- Journal of Neuroscience, 2018, v. 38, n. 6, p. 1335, doi. 10.1523/JNEUROSCI.2793-17.2017
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- Article
Expression profiling suggests microglial impairment in human immunodeficiency virus neuropathogenesis.
- Published in:
- 2018
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- Publication type:
- journal article
Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease.
- Published in:
- Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0411-2
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- Publication type:
- Article
Deletion of Neurotrophin Signaling through the Glucocorticoid Receptor Pathway Causes Tau Neuropathology.
- Published in:
- Scientific Reports, 2016, p. 37231, doi. 10.1038/srep37231
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- Publication type:
- Article
TAU MODULATES BDNF EXPRESSION AND MEDIATES Aβ-INDUCED BDNF DOWN-REGULATION IN ANIMAL AND CELLULAR MODELS OF ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1045, doi. 10.1016/j.jalz.2016.06.2175
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- Publication type:
- Article
Brain-Wide Insulin Resistance, Tau Phosphorylation Changes, and Hippocampal Neprilysin and Amyloid-β Alterations in a Monkey Model of Type 1 Diabetes.
- Published in:
- Journal of Neuroscience, 2016, v. 36, n. 15, p. 4248, doi. 10.1523/JNEUROSCI.4640-14.2016
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- Publication type:
- Article
Calorie Restriction Suppresses Age-Dependent Hippocampal Transcriptional Signatures.
- Published in:
- PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0133923
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- Publication type:
- Article
Withdrawal of BDNF from hippocampal cultures leads to changes in genes involved in synaptic function.
- Published in:
- Developmental Neurobiology (19328451), 2015, v. 75, n. 2, p. 173, doi. 10.1002/dneu.22216
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- Publication type:
- Article
Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice.
- Published in:
- Journal of Comparative Neurology, 2015, v. 523, n. 1, p. 61, doi. 10.1002/cne.23663
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- Publication type:
- Article
Maternal choline supplementation programs greater activity of the phosphatidylethanolamine N-methyltransferase (PEMT) pathway in adult Ts65Dn trisomic mice.
- Published in:
- FASEB Journal, 2014, v. 28, n. 10, p. 4312, doi. 10.1096/fj.14-251736
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- Publication type:
- Article
Maternal choline supplementation differentially alters the basal forebrain cholinergic system of young-adult Ts65Dn and disomic mice.
- Published in:
- Journal of Comparative Neurology, 2014, v. 522, n. 6, p. 1390, doi. 10.1002/cne.23492
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- Publication type:
- Article
Glutamatergic Transmission Aberration: A Major Cause of Behavioral Deficits in a Murine Model of Down's Syndrome.
- Published in:
- Journal of Neuroscience, 2014, v. 34, n. 15, p. 5099, doi. 10.1523/JNEUROSCI.5338-13.2014
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- Publication type:
- Article