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Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain.
Published in:
EMBO Journal, 2002, v. 21, n. 23, p. 6494, doi. 10.1093/emboj/cdf641
By:
- Hill, Justine M.;
- Vaidyanathan, Hema;
- Ramos, Joe W.;
- Ginsberg, Mark H.;
- Werner, Milton H.
Publication type:
Article
The antithrombotic potential of selective blockade of talin-dependent integrin alpha IIb beta 3 (platelet GPIIb-IIIa) activation.
Published in:
2007
By:
- Petrich, Brian G.;
- Fogelstrand, Per;
- Partridge, Anthony W.;
- Yousefi, Nima;
- Ablooglu, Ararat J.;
- Shattil, Sanford J.;
- Ginsberg, Mark H.
Publication type:
journal article
Blocking the α4 integrin-paxillin interaction selectively impairs mononuclear leukocyte recruitment to an inflammatory site.
Published in:
Journal of Clinical Investigation, 2006, v. 116, n. 3, p. 715, doi. 10.1172/JCI26091
By:
- Féral, Chloé C.;
- Rose, David M.;
- Jaewon Han;
- Fox, Norma;
- Silverman, Gregg J.;
- Kaushansky, Kenneth;
- Ginsberg, Mark H.
Publication type:
Article
Genetic Interaction Between Integrins and moleskin, a Gene Encoding a Drosophila Homolog of Importin-7.
Published in:
Genetics, 2002, v. 162, n. 1, p. 285, doi. 10.1093/genetics/162.1.285
By:
- Baker, Scott E.;
- Lorenzen, James A.;
- Miller, Steven W.;
- Bunch, Thomas A.;
- Jannuzi, Alison L.;
- Ginsberg, Mark H.;
- Perkins, Lizabeth A.;
- Brower, Danny L.
Publication type:
Article
Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations.
Published in:
eLife, 2021, p. 1, doi. 10.7554/eLife.62155
By:
- Wenqing Li;
- Tran, Virginia;
- Shaked, Iftach;
- Xue, Belinda;
- Moore, Thomas;
- Lightle, Rhonda;
- Kleinfeld, David;
- Awad, Issam A.;
- Ginsberg, Mark H.
Publication type:
Article
Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations.
Published in:
eLife, 2021, p. 1, doi. 10.7554/eLife.62155
By:
- Wenqing Li;
- Tran, Virginia;
- Shaked, Iftach;
- Xue, Belinda;
- Moore, Thomas;
- Lightle, Rhonda;
- Kleinfeld, David;
- Awad, Issam A.;
- Ginsberg, Mark H.
Publication type:
Article
Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity.
Published in:
eLife, 2016, p. 1, doi. 10.7554/eLife.11394
By:
- de Kreuk, Bart-Jan;
- Gingras, Alexandre R.;
- Knight, James D. R.;
- Liu, Jian J.;
- Gingras, Anne-Claude;
- Ginsberg, Mark H.
Publication type:
Article
Serum factors releasing serotonin from normal platelets: relation to the manifestations of systemic lupus erythematosus.
Published in:
1977
By:
- Ginsberg, Mark H.;
- O'Malley, Michael;
- Ginsberg, M H;
- O'Malley, M
Publication type:
journal article
Corrigendum: Regulation of cardiovascular development and integrity by the heart of glass– cerebral cavernous malformation protein pathway.
Published in:
2009
By:
- Kleaveland, Benjamin;
- Zheng, Xiangjian;
- Liu, Jian J;
- Blum, Yannick;
- Tung, Jennifer J;
- Zou, Zhiying;
- Sweeney, Shawn M;
- Chen, Mei;
- Guo, Lili;
- Lu, Min-min;
- Zhou, Diane;
- Kitajewski, Jan;
- Affolter, Markus;
- Ginsberg, Mark H;
- Kahn, Mark L
Publication type:
Correction Notice
Regulation of cardiovascular development and integrity by the heart of glass–cerebral cavernous malformation protein pathway.
Published in:
Nature Medicine, 2009, v. 15, n. 2, p. 169, doi. 10.1038/nm.1918
By:
- Kleaveland, Benjamin;
- Zheng, Xiangjian;
- Liu, Jian J;
- Blum, Yannick;
- Tung, Jennifer J;
- Zou, Zhiying;
- Chen, Mei;
- Guo, Lili;
- Lu, Min-min;
- Zhou, Diane;
- Kitajewski, Jan;
- Affolter, Markus;
- Ginsberg, Mark H;
- Kahn, Mark L
Publication type:
Article
Corrigendum: Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.
Published in:
2008
By:
- Jones, Christopher A.;
- London, Nyall R.;
- Haoyu Chen;
- Kye Won Park;
- Sauvaget, Dominique;
- Stockton, Rebecca A.;
- Wythe, Joshua D.;
- Wonhee Suh;
- Larrieu-Lahargue, Frederic;
- Mukouyama, Yoh-suke;
- Lindblom, Per;
- Seth, Pankaj;
- Frias, Antonio;
- Nishiya, Naoyuki;
- Ginsberg, Mark H.;
- Gerhardt, Holger;
- Kang Zhang;
- Li, Dean Y.
Publication type:
Correction Notice
Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.
Published in:
Nature Medicine, 2008, v. 14, n. 4, p. 448, doi. 10.1038/nm1742
By:
- Jones, Christopher A.;
- London, Nyall R.;
- Haoyu Chen;
- Kye Won Park;
- Sauvaget, Dominique;
- Stockton, Rebecca A.;
- Wythe, Joshua D.;
- Wonhee Suh;
- Larrieu-Lahargue, Frederic;
- Mukouyama, Yoh-suke;
- Lindblom, Per;
- Seth, Pankaj;
- Frias, Antonio;
- Nishiya, Naoyuki;
- Ginsberg, Mark H;
- Gerhardt, Holger;
- Kang Zhang;
- Li, Dean Y
Publication type:
Article
The final steps of integrin activation: the end game.
Published in:
Nature Reviews Molecular Cell Biology, 2010, v. 11, n. 4, p. 288, doi. 10.1038/nrm2871
By:
- Shattil, Sanford J.;
- Kim, Chungho;
- Ginsberg, Mark H.
Publication type:
Article
RAS GTPases: INTEGRINS' FRIENDS OR FOES?
Published in:
Nature Reviews Molecular Cell Biology, 2003, v. 4, n. 10, p. 767, doi. 10.1038/nrm1229
By:
- Kinbara, Kayoko;
- Goldfinger, Lawrence E.;
- Hansen, Malene;
- Fan-Li Chou;
- Ginsberg, Mark H.
Publication type:
Article
α4β1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with α4-cytoplasmic domain.
Published in:
Journal of Cell Biology, 2005, v. 171, n. 6, p. 1073, doi. 10.1083/jcb.200503155
By:
- Alon, Ronen;
- Feigelson, Sara W.;
- Manevich, Eugenia;
- Rose, David M.;
- Schmitz, Julia;
- Overby, Darryl R.;
- Winter, Eitan;
- Grabovsky, Valentin;
- Shinder, Vera;
- Matthews, Benjamin D.;
- Sokolovsky-Eisenberg, Maya;
- Ingber, Donald E.;
- Benoit, Martin;
- Ginsberg, Mark H.
Publication type:
Article
Spatial restriction of α4 integrin phosphorylation regulates lamellipodial stability and α4β1-dependent cell migration.
Published in:
Journal of Cell Biology, 2003, v. 162, n. 4, p. 731, doi. 10.1083/jcb.200304031
By:
- Goldfinger, Lawrence E.;
- Jaewon Han;
- Kiosses, William B.;
- Howe, Alan K.;
- Ginsberg, Mark H.
Publication type:
Article
Platelet activation by a relapsing fever spirochaete results in enhanced bacterium–platelet interaction via integrin αIIbβ3 activation.
Published in:
Molecular Microbiology, 2001, v. 39, n. 2, p. 330, doi. 10.1046/j.1365-2958.2001.02201.x
By:
- Alugupalli, Kishore R.;
- Michelson, Alan D.;
- Barnard, Marc R.;
- Robbins, Douglas;
- Coburn, Jenifer;
- Baker, Elizabeth K.;
- Ginsberg, Mark H.;
- Schwan, Tom G.;
- Leong, John M.
Publication type:
Article
Kindlins, Integrin Activation and the Regulation of Talin Recruitment to αIIbβ3.
Published in:
PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0034056
By:
- Kahner, Bryan N.;
- Kato, Hisashi;
- Banno, Asoka;
- Ginsberg, Mark H.;
- Shattil, Sanford J.;
- Ye, Feng
Publication type:
Article
High Refractive Index Silicone Gels for Simultaneous Total Internal Reflection Fluorescence and Traction Force Microscopy of Adherent Cells.
Published in:
PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0023807
By:
- Gutierrez, Edgar;
- Tkachenko, Eugene;
- Besser, Achim;
- Sundd, Prithu;
- Ley, Klaus;
- Danuser, Gaudenz;
- Ginsberg, Mark H.;
- Groisman, Alex
Publication type:
Article
Transcriptomic signatures of individual cell types in cerebral cavernous malformation.
Published in:
Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-023-01301-2
By:
- Li, Ying;
- Girard, Romuald;
- Srinath, Abhinav;
- Cruz, Diana Vera;
- Ciszewski, Cezary;
- Chen, Chang;
- Lightle, Rhonda;
- Romanos, Sharbel;
- Sone, Je Yeong;
- Moore, Thomas;
- DeBiasse, Dorothy;
- Stadnik, Agnieszka;
- Lee, Justine J.;
- Shenkar, Robert;
- Koskimäki, Janne;
- Lopez-Ramirez, Miguel A.;
- Marchuk, Douglas A.;
- Ginsberg, Mark H.;
- Kahn, Mark L.;
- Shi, Changbin
Publication type:
Article
R-Ras C-terminal sequences are sufficient to confer R-Ras specificity to H-Ras.
Published in:
Oncogene, 2002, v. 21, n. 28, p. 4448, doi. 10.1038/sj.onc.1205538
By:
- Hansen, Malene;
- Rusyn, Elena V.;
- Hughes, Paul E.;
- Ginsberg, Mark H.;
- Cox, Adrienne D.;
- Willumsen, Berthe M.
Publication type:
Article
The structure of an integrin/talin complex reveals the basis of inside-out signal transduction.
Published in:
EMBO Journal, 2009, v. 28, n. 22, p. 3623, doi. 10.1038/emboj.2009.287
By:
- Anthis, Nicholas J.;
- Wegener, Kate L.;
- Feng Ye;
- Chungho Kim;
- Goult, Benjamin T.;
- Lowe, Edward D.;
- Vakonakis, Ioannis;
- Bate, Neil;
- Critchley, David R.;
- Ginsberg, Mark H.;
- Campbell, Iain D.
Publication type:
Article
The structure of the integrin αIIbβ3 transmembrane complex explains integrin transmembrane signalling.
Published in:
EMBO Journal, 2009, v. 28, n. 9, p. 1351, doi. 10.1038/emboj.2009.63
By:
- Tong-Lay Lau;
- Chungho Kim;
- Ginsberg, Mark H.;
- Ulmer, Tobias S.
Publication type:
Article
Neurite outgrowth on a fibronectin isoform expressed during peripheral nerve regeneration is mediated by the interaction of paxillin with α4β1 integrins.
Published in:
BMC Neuroscience, 2007, v. 8, p. 1, doi. 10.1186/1471-2202-8-44
By:
- Vogelezang, Mariette;
- Forster, Ulrike B.;
- Jaewon Han;
- Ginsberg, Mark H.;
- ffrench-Constant, Charles
Publication type:
Article
Direct evidence for the interaction of platelet surface membrane proteins GPIIb and III with cytoskeletal components: Protein crosslinking studies.
Published in:
Journal of Cellular Biochemistry, 1985, v. 27, n. 3, p. 277, doi. 10.1002/jcb.240270309
By:
- Painter, Richard G.;
- Gaarde, William;
- Ginsberg, Mark H.
Publication type:
Article
Integrin-associated proteins as potential therapeutic targets.
Published in:
Immunological Reviews, 2008, v. 223, n. 1, p. 236, doi. 10.1111/j.1600-065X.2008.00640.x
By:
- Cantor, Joseph M.;
- Ginsberg, Mark H.;
- Rose, David M.
Publication type:
Article
Integrin modulation and signaling in leukocyte adhesion and migration.
Published in:
Immunological Reviews, 2007, v. 218, n. 1, p. 126, doi. 10.1111/j.1600-065X.2007.00536.x
By:
- Rose, David M.;
- Alon, Ronen;
- Ginsberg, Mark H.
Publication type:
Article
α4 integrins and the immune response.
Published in:
Immunological Reviews, 2002, v. 186, n. 1, p. 118, doi. 10.1034/j.1600-065X.2002.18611.x
By:
- Rose, David M.;
- Han, Jaewon;
- Ginsberg, Mark H.
Publication type:
Article
Protein kinase A governs a RhoA-RhoGDI protrusion-retraction pacemaker in migrating cells.
Published in:
Nature Cell Biology, 2011, v. 13, n. 6, p. 661, doi. 10.1038/ncb2231
By:
- Tkachenko, Eugene;
- Sabouri-Ghomi, Mohsen;
- Pertz, Olivier;
- Kim, Chungho;
- Gutierrez, Edgar;
- Machacek, Matthias;
- Groisman, Alex;
- Danuser, Gaudenz;
- Ginsberg, Mark H.
Publication type:
Article
Slit2–Robo4 signalling promotes vascular stability by blocking Arf6 activity.
Published in:
Nature Cell Biology, 2009, v. 11, n. 11, p. 1325, doi. 10.1038/ncb1976
By:
- Jones, Christopher A.;
- Nishiya, Naoyuki;
- London, Nyall R.;
- Zhu, Weiquan;
- Sorensen, Lise K.;
- Chan, Aubrey C.;
- Lim, Chinten J.;
- Chen, Haoyu;
- Zhang, Qisheng;
- Schultz, Peter G.;
- Hayallah, Alaa M.;
- Thomas, Kirk R.;
- Famulok, Michael;
- Zhang, Kang;
- Ginsberg, Mark H.;
- Li, Dean Y.
Publication type:
Article
Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration.
Published in:
Nature Cell Biology, 2009, v. 11, n. 5, p. 624, doi. 10.1038/ncb1868
By:
- Cai Huang;
- Zenon Rajfur;
- Nima Yousefi;
- Zaozao Chen;
- Jacobson, Ken;
- Ginsberg, Mark H.
Publication type:
Article
α4 Integrins are Type I cAMP-dependent protein kinase-anchoring proteins.
Published in:
Nature Cell Biology, 2007, v. 9, n. 4, p. 415, doi. 10.1038/ncb1561
By:
- Lim, Chinten James;
- Jaewon Han;
- Yousefi, Nima;
- Yuliang Ma;
- Amieux, Paul S.;
- McKnight, G. Stanley;
- Taylor, Susan S.;
- Ginsberg, Mark H.
Publication type:
Article
Ana4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells.
Published in:
Nature Cell Biology, 2005, v. 7, n. 4, p. 343, doi. 10.1038/ncb1234
By:
- Nishiya, Naoyuki;
- Kiosses, William B.;
- Han, Jaewon;
- Ginsberg, Mark H.
Publication type:
Article
Talin forges the links between integrins and actin.
Published in:
Nature Cell Biology, 2003, v. 5, n. 8, p. 694, doi. 10.1038/ncb0803-694
By:
- Calderwood, David A.;
- Ginsberg, Mark H.
Publication type:
Article
Networks and crosstalk: integrin signalling spreads.
Published in:
Nature Cell Biology, 2002, v. 4, n. 4, p. E65, doi. 10.1038/ncb0402-e65
By:
- Schwartz, Martin A.;
- Ginsberg, Mark H.
Publication type:
Article
Increased filamin binding to β-integrin cytoplasmic domains inhibits cell migration.
Published in:
Nature Cell Biology, 2001, v. 3, n. 12, p. 1060, doi. 10.1038/ncb1201-1060
By:
- Calderwood, David A.;
- Huttenlocher, Anna;
- Kiosses, William B.;
- Rose, David M.;
- Woodside, Darren G.;
- Schwartz, Martin A.;
- Ginsberg, Mark H.
Publication type:
Article
β1 integrin monoclonal antibody treatment ameliorates cerebral cavernous malformations.
Published in:
FASEB Journal, 2022, v. 36, n. 12, p. 1, doi. 10.1096/fj.202200907RR
By:
- McCurdy, Sara;
- Lin, Jenny;
- Shenkar, Robert;
- Moore, Thomas;
- Lightle, Rhonda;
- Faurobert, Eva;
- Lopez‐Ramirez, Miguel‐Alejandro;
- Awad, Issam;
- Ginsberg, Mark H.
Publication type:
Article
Propranolol inhibits cavernous vascular malformations by β1 adrenergic receptor antagonism in animal models.
Published in:
2021
By:
- Wenqing Li;
- Shenkar, Robert;
- Detter, Mathew R.;
- Moore, Thomas;
- Benavides, Christian;
- Lightle, Rhonda;
- Girard, Romuald;
- Hobson, Nicholas;
- Ying Cao;
- Yan Li;
- Griffin, Erin;
- Gallione, Carol;
- Zabramski, Joseph M.;
- Ginsberg, Mark H.;
- Marchuk, Douglas A.;
- Awad, Issam A.;
- Li, Wenqing;
- Cao, Ying;
- Li, Yan
Publication type:
journal article
Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 4, p. 1471, doi. 10.1172/JCI79329
By:
- Rothmeier, Andrea S.;
- Marchese, Patrizia;
- Petrich, Brian G.;
- Furlan-Freguia, Christian;
- Ginsberg, Mark H.;
- Ruggeri, Zaverio M.;
- Ruf, Wolfram
Publication type:
Article
CD98hc facilitates B cell proliferation and adaptive humoral immunity.
Published in:
Nature Immunology, 2009, v. 10, n. 4, p. 412, doi. 10.1038/ni.1712
By:
- Cantor, Joseph;
- Browne, Cecille D;
- Ruppert, Raphael;
- Féral, Chloé C;
- Fässler, Reinhard;
- Rickert, Robert C;
- Ginsberg, Mark H
Publication type:
Article
The T Cell Receptor SLAPs Integrins Together.
Published in:
Nature Immunology, 2001, v. 2, n. 10, p. 904, doi. 10.1038/ni1001-904
By:
- Woodside, Darren G.;
- Shattil, Sanford J.;
- Ginsberg, Mark H.
Publication type:
Article
A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration.
Published in:
Nature Communications, 2015, v. 6, n. 9, p. 8492, doi. 10.1038/ncomms9492
By:
- Lagarrigue, Frederic;
- Vikas Anekal, Praju;
- Lee, Ho-Sup;
- Bachir, Alexia I.;
- Ablack, Jailal N.;
- Horwitz, Alan F.;
- Ginsberg, Mark H.
Publication type:
Article
The Cerebral Cavernous Malformation1 (CCM1) Gene Product, KRIT-1, is a Rapl Effector that Regulates Endothelial Cell-Cell Junctions.
Published in:
FASEB Journal, 2007, v. 21, n. 5, p. A187
By:
- Glading, Angela;
- Jaewon Han;
- Stockton, Rebecca;
- Ginsberg, Mark H.
Publication type:
Article
Recreation of the terminal events in physiological integrin activation.
Published in:
Journal of Cell Biology, 2010, v. 188, n. 1, p. 157, doi. 10.1083/jcb.200908045
By:
- Ye, Feng;
- Hu, Guiqing;
- Taylor, Dianne;
- Ratnikov, Boris;
- Bobkov, Andrey A.;
- McLean, Mark A.;
- Sligar, Stephen G.;
- Taylor, Kenneth A.;
- Ginsberg, Mark H.
Publication type:
Article
Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin αllbβ3.
Published in:
Journal of Cell Biology, 2008, v. 181, n. 7, p. 1211, doi. 10.1083/jcb.200803094
By:
- Watanabe, Naohide;
- Bodin, Laurent;
- Pandey, Manjula;
- Krause, Matthias;
- Coughlin, Shaun;
- Boussiotis, Vassiliki A.;
- Ginsberg, Mark H.;
- Shattil, Sanford J.
Publication type:
Article
KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell--cell junctions.
Published in:
Journal of Cell Biology, 2007, v. 179, n. 2, p. 247, doi. 10.1083/jcb.200705175
By:
- Glading, Angela;
- Han, Jaewon;
- Stockton, Rebecca A.;
- Ginsberg, Mark H.
Publication type:
Article
CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling.
Published in:
Journal of Cell Biology, 2007, v. 178, n. 4, p. 701
By:
- Féral, Chloé C.;
- Zijlstra, Andries;
- Tkachenko, Eugene;
- Prager, Gerald;
- Gardel, Margaret L.;
- Slepak, Marina;
- Ginsberg, Mark H.
Publication type:
Article
Syk, c-Src, the αvβ3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption.
Published in:
Journal of Cell Biology, 2007, v. 176, n. 6, p. 877, doi. 10.1083/jcb.200611083
By:
- Wei Zou;
- Kitaura, Hideki;
- Reeve, Jennifer;
- Long, Fanxin;
- Tybulewicz, Victor L. J.;
- Shattil, Sanford J.;
- Ginsberg, Mark H.;
- Ross, F. Patrick;
- Teitelbaum, Steven L.
Publication type:
Article
RLIP76 (RalBP1) is an R-Ras effector that mediates adhesion-dependent Rac activation and cell migration.
Published in:
Journal of Cell Biology, 2006, v. 174, n. 6, p. 877, doi. 10.1083/jcb.200603111
By:
- Goldfinger, Lawrence E.;
- Ptak, Celeste;
- Jeffery, Erin D.;
- Shabanowitz, Jeffrey;
- Hunt, Donald F.;
- Ginsberg, Mark H.
Publication type:
Article
Antitumor activity of an anti- CD98 antibody.
Published in:
International Journal of Cancer, 2015, v. 137, n. 3, p. 710, doi. 10.1002/ijc.29415
By:
- Hayes, Gregory M.;
- Chinn, Lawrence;
- Cantor, Joseph M.;
- Cairns, Belinda;
- Levashova, Zoia;
- Tran, Hoang;
- Velilla, Timothy;
- Duey, Dana;
- Lippincott, John;
- Zachwieja, Joseph;
- Ginsberg, Mark H.;
- H. van der Horst, Edward
Publication type:
Article

Found: 61