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Intranasal HD-Ad-FS vaccine induces systemic and airway mucosal immunities against SARS-CoV-2 and systemic immunity against SARS-CoV-2 variants in mice and hamsters.
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- Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1430928
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FAM72A degrades UNG2 through the GID/CTLH complex to promote mutagenic repair during antibody maturation.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52009-x
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- Article
ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis.
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- Life Science Alliance, 2024, v. 7, n. 1, p. 1, doi. 10.26508/lsa.202302335
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- Article
Kindlin2 enables EphB/ephrinB bi-directional signaling to support vascular development.
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- Life Science Alliance, 2023, v. 6, n. 3, p. 1, doi. 10.26508/lsa.202201800
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CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7.
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- Life Science Alliance, 2022, v. 5, n. 11, p. 1, doi. 10.26508/lsa.202201527
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- Article
Gastrin induces phosphorylation of eIF4E binding protein 1 and translation initiation of ornithine decarboxylase mRNA.
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- Oncogene, 1998, v. 16, n. 17, p. 2219, doi. 10.1038/sj.onc.1201748
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Omicron variant neutralizing antibodies following BNT162b2 BA.4/5 versus mRNA-1273 BA.1 bivalent vaccination in patients with end-stage kidney disease.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41678-9
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- Article
The induction of SHP-1 degradation by TAOK3 ensures the responsiveness of T cells to TCR stimulation.
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- Science Signaling, 2024, v. 17, n. 817, p. 1, doi. 10.1126/scisignal.adg4422
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- Article
Omicron BA.4/5 Neutralization and T-Cell Responses in Organ Transplant Recipients After Booster Messenger RNA Vaccine: A Multicenter Cohort Study.
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- Clinical Infectious Diseases, 2023, v. 77, n. 2, p. 229, doi. 10.1093/cid/ciad175
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Beyond hairballs: The use of quantitative mass spectrometry data to understand protein–protein interactions
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- FEBS Letters, 2012, v. 586, n. 17, p. 2723, doi. 10.1016/j.febslet.2012.03.065
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Palmitoylation Targets the Calcineurin Phosphatase to the Phosphatidylinositol 4‐kinase Complex at the Plasma Membrane.
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- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R6277
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- Article
Proximity‐dependent sensors for signaling.
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- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.0I112
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SLC3A2 N‐glycosylation and alternate evolutionary trajectories for amino acid metabolism.
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- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.0I108
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Proximity‐Dependent Sensors Reveal New Mechanisms of mTORC1 Activation by Amino Acids.
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- FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.04507
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- Article
Enhancing detection of SARS-CoV-2 re-infections using longitudinal sero-monitoring: demonstration of a methodology in a cohort of people experiencing homelessness in Toronto, Canada.
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- BMC Infectious Diseases, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12879-024-09013-9
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Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fungal pathogen.
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- PLoS Biology, 2019, v. 17, n. 7, p. 1, doi. 10.1371/journal.pbio.3000358
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Proteomic Analysis of Histones H2A/H2B and Variant Hv1 in Tetrahymena thermophila Reveals an Ancient Network of Chaperones.
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- Molecular Biology & Evolution, 2019, v. 36, n. 5, p. 1037, doi. 10.1093/molbev/msz039
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- Article
Declining Levels of Neutralizing Antibodies to SARS-CoV-2 Omicron Variants Are Enhanced by Hybrid Immunity and Original/Omicron Bivalent Vaccination.
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- Vaccines, 2024, v. 12, n. 6, p. 564, doi. 10.3390/vaccines12060564
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Predictors of Breakthrough SARS-CoV-2 Infection after Vaccination.
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- Vaccines, 2024, v. 12, n. 1, p. 36, doi. 10.3390/vaccines12010036
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ESRP1 controls biogenesis and function of a large abundant multiexon circRNA.
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- Nucleic Acids Research, 2024, v. 52, n. 3, p. 1387, doi. 10.1093/nar/gkad1138
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The function of BCL11B in base excision repair contributes to its dual role as an oncogene and a haplo-insufficient tumor suppressor gene.
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- Nucleic Acids Research, 2024, v. 52, n. 1, p. 223, doi. 10.1093/nar/gkad1037
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Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.
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- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01326-5
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Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry.
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- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00249-5
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- Article
CCM-3/STRIPAK promotes seamless tube extension through endocytic recycling.
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- Nature Communications, 2015, v. 6, n. 3, p. 6449, doi. 10.1038/ncomms7449
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Mechanistic insight into GPCR-mediated activation of the microtubule-associated RhoA exchange factor GEF-H1.
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- Nature Communications, 2014, v. 5, n. 9, p. 4857, doi. 10.1038/ncomms5857
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- Article
MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.
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- Science Signaling, 2017, v. 10, n. 503, p. 1, doi. 10.1126/scisignal.aan3286
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Dried blood spot specimens for SARS-CoV-2 antibody testing: A multi-site, multi-assay comparison.
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- PLoS ONE, 2021, v. 16, n. 12, p. 1, doi. 10.1371/journal.pone.0261003
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence: Navigating the absence of a gold standard.
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- PLoS ONE, 2021, v. 16, n. 9, p. 1, doi. 10.1371/journal.pone.0257743
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Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI.
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- EMBO Journal, 2000, v. 19, n. 3, p. 434, doi. 10.1093/emboj/19.3.434
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- Article
Proteomic Profiling of the TRAF3 Interactome Network Reveals a New Role for the ER-to-Golgi Transport Compartments in Innate Immunity.
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- PLoS Pathogens, 2012, v. 8, n. 7, p. 1, doi. 10.1371/journal.ppat.1002747
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Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1.
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- Nature, 2010, v. 466, n. 7309, p. 941, doi. 10.1038/nature09297
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Adapting Serosurveys for the SARS-CoV-2 Vaccine Era.
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- Open Forum Infectious Diseases, 2022, v. 9, n. 2, p. 1, doi. 10.1093/ofid/ofab632
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TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.62857
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A Comprehensive, Flexible Collection of SARS-CoV-2 Coding Regions.
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- G3: Genes | Genomes | Genetics, 2020, v. 10, n. 9, p. 1, doi. 10.1534/g3.120.401554
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SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome.
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- EMBO Molecular Medicine, 2016, v. 8, n. 9, p. 1019, doi. 10.15252/emmm.201506159
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Retention of hemostatic and immunological properties of frozen plasma and COVID‐19 convalescent apheresis fresh‐frozen plasma produced and freeze‐dried in Canada.
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- Transfusion, 2022, v. 62, n. 2, p. 418, doi. 10.1111/trf.16772
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Resistance of SARS‐CoV‐2 beta and gamma variants to plasma collected from Canadian blood donors during the spring of 2020.
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- Transfusion, 2022, v. 62, n. 1, p. 37, doi. 10.1111/trf.16713
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Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.
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- Molecular Systems Biology, 2024, v. 20, n. 6, p. 719, doi. 10.1038/s44320-024-00032-x
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- Article
Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity.
- Published in:
- eLife, 2016, p. 1, doi. 10.7554/eLife.11394
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- Article
A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09829-z
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- Article
A feed forward loop enforces YAP/TAZ signaling during tumorigenesis.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05939-2
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- Article
ProHits: integrated software for mass spectrometry-based interaction proteomics.
- Published in:
- Nature Biotechnology, 2010, v. 28, n. 10, p. 1015, doi. 10.1038/nbt1010-1015
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Two‐phase Bayesian latent class analysis to assess diagnostic test performance in the absence of a gold standard: COVID‐19 serological assays as a proof of concept.
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- Vox Sanguinis, 2023, v. 118, n. 12, p. 1069, doi. 10.1111/vox.13545
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TRK-Fused Gene (TFG), a protein involved in protein secretion pathways, is an essential component of the antiviral innate immune response.
- Published in:
- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009111
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35 years later, mRNA caps still matter.
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- Nature Reviews Molecular Cell Biology, 2009, v. 10, n. 11, p. 735, doi. 10.1038/nrm2789
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Analysis of protein complexes using mass spectrometry.
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- Nature Reviews Molecular Cell Biology, 2007, v. 8, n. 8, p. 645, doi. 10.1038/nrm2208
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- Article
Humoral Response Following 3 Doses of mRNA COVID-19 Vaccines in Patients With Non-Dialysis-Dependent CKD: An Observational Study.
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- Canadian Journal of Kidney Health & Disease, 2024, p. 1, doi. 10.1177/20543581231224127
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Advances in protein complex analysis using mass spectrometry.
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- Journal of Physiology, 2005, v. 563, n. 1, p. 11, doi. 10.1113/jphysiol.2004.080440
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- Article
The endosomal sorting adaptor HD-PTP is required for ephrin-B:EphB signalling in cellular collapse and spinal motor axon guidance.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-48421-9
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- Article
Palmitoylation targets the calcineurin phosphatase to the phosphatidylinositol 4-kinase complex at the plasma membrane.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26326-4
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- Article