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Innovative Tools for DNA Topology Probing in Human Cells Reveal a Build-Up of Positive Supercoils Following Replication Stress at Telomeres and at the FRA3B Fragile Site.
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- Cells (2073-4409), 2024, v. 13, n. 16, p. 1361, doi. 10.3390/cells13161361
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- Article
mTert induction in p21-positive cells counteracts capillary rarefaction and pulmonary emphysema.
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- EMBO Reports, 2024, v. 25, n. 3, p. 1650, doi. 10.1038/s44319-023-00041-1
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- Article
Non-canonical telomere protection role of FOXO3a of human skeletal muscle cells regulated by the TRF2-redox axis.
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- Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-04903-1
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- Article
Senescence‐associated transcriptional derepression in subtelomeres is determined in a chromosome‐end‐specific manner.
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- Aging Cell, 2023, v. 22, n. 5, p. 1, doi. 10.1111/acel.13804
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- Publication type:
- Article
Protein phosphatase 2A activators reverse age‐related behavioral changes by targeting neural cell senescence.
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- Aging Cell, 2023, v. 22, n. 3, p. 1, doi. 10.1111/acel.13780
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- Article
Telomeres are shorter in wild Saccharomyces cerevisiae isolates than in domesticated ones.
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- Genetics, 2023, v. 223, n. 3, p. 1, doi. 10.1093/genetics/iyac186
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- Article
Telomere dysfunction is associated with dark‐induced bleaching in the reef coral Stylophora pistillata.
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- Molecular Ecology, 2022, v. 31, n. 23, p. 6087, doi. 10.1111/mec.16199
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- Article
non-telomeric evolutionary trajectory of TRF2 in zebrafish reveals its specific roles in neurodevelopment and aging.
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- Nucleic Acids Research, 2022, v. 50, n. 4, p. 2081, doi. 10.1093/nar/gkac065
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- Article
Telomerase is required for glomerular renewal in kidneys of adult mice.
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- NPJ Regenerative Medicine, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41536-022-00212-z
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- Article
Loss of atm in Zebrafish as a Model of Ataxia–Telangiectasia Syndrome.
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- Biomedicines, 2022, v. 10, n. 2, p. 392, doi. 10.3390/biomedicines10020392
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- Article
Multifunctionality of the Telomere-Capping Shelterin Complex Explained by Variations in Its Protein Composition.
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- Cells (2073-4409), 2021, v. 10, n. 7, p. 1753, doi. 10.3390/cells10071753
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- Article
A Novel Screen for Expression Regulators of the Telomeric Protein TRF2 Identified Small Molecules That Impair TRF2 Dependent Immunosuppression and Tumor Growth.
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- Cancers, 2021, v. 13, n. 12, p. 2998, doi. 10.3390/cancers13122998
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- Article
Neutrophils: mediating TelOxidation and senescence.
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- EMBO Journal, 2021, v. 40, n. 9, p. 1, doi. 10.15252/embj.2021108164
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- Article
The Power of Stress: The Telo-Hormesis Hypothesis.
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- Cells (2073-4409), 2021, v. 10, n. 5, p. 1156, doi. 10.3390/cells10051156
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- Article
The Telomeric Protein TRF2 Regulates Replication Origin Activity within Pericentromeric Heterochromatin.
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- Life (2075-1729), 2021, v. 11, n. 4, p. 267, doi. 10.3390/life11040267
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- Article
Les horloges de la longévité: Le rôle promoteur des télomères ?
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- Médecine Sciences, 2020, v. 36, n. 12, p. 1113, doi. 10.1051/medsci/2020242
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- Article
Longevity strategies in response to light in the reef coral Stylophora pistillata.
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- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-76925-2
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- Article
Human RAP1 specifically protects telomeres of senescent cells from DNA damage.
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- EMBO Reports, 2020, v. 21, n. 4, p. 1, doi. 10.15252/embr.201949076
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- Article
Mitochondrial function in skeletal myofibers is controlled by a TRF2‐SIRT3 axis over lifetime.
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- Aging Cell, 2020, v. 19, n. 3, p. 1, doi. 10.1111/acel.13097
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- Article
Un objectif de santé publique : le vieillissement durable.
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- 2020
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- Publication type:
- Editorial
The Tara Pacific expedition—A pan-ecosystemic approach of the “-omics” complexity of coral reef holobionts across the Pacific Ocean.
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- PLoS Biology, 2019, v. 17, n. 9, p. 1, doi. 10.1371/journal.pbio.3000483
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- Article
Inhibiting TRF1 upstream signaling pathways to target telomeres in cancer cells.
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- EMBO Molecular Medicine, 2019, v. 11, n. 7, p. N.PAG, doi. 10.15252/emmm.201910845
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- Publication type:
- Article
Cancer cells induce immune escape via glycocalyx changes controlled by the telomeric protein TRF2.
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- EMBO Journal, 2019, v. 38, n. 11, p. N.PAG, doi. 10.15252/embj.2018100012
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- Publication type:
- Article
TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment.
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- Nucleic Acids Research, 2019, v. 47, n. 7, p. 3365, doi. 10.1093/nar/gkz041
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- Publication type:
- Article
The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again.
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- Cancers, 2019, v. 11, n. 2, p. 250, doi. 10.3390/cancers11020250
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- Article
SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.
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- Nucleic Acids Research, 2017, v. 45, n. 4, p. 1820, doi. 10.1093/nar/gkw1202
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- Publication type:
- Article
Nitric Oxide Synthase 2 Improves Proliferation and Glycolysis of Peripheral γδ T Cells.
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- PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0165639
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- Article
Understanding why we age and how: Evolutionary biology meets different model organisms and multi-level omics.
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- BioEssays, 2016, v. 38, n. 6, p. 494, doi. 10.1002/bies.201600049
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- Publication type:
- Article
High expression of TRF2, SOX10, and CD10 in circulating tumor microemboli detected in metastatic melanoma patients. A potential impact for the assessment of disease aggressiveness.
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- Cancer Medicine, 2016, v. 5, n. 6, p. 1022, doi. 10.1002/cam4.661
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- Article
Differential senescence capacities in meibomian gland carcinoma and basal cell carcinoma.
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- International Journal of Cancer, 2016, v. 138, n. 6, p. 1442, doi. 10.1002/ijc.29882
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- Publication type:
- Article
Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance.
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- Nucleic Acids Research, 2016, v. 44, n. 4, p. 1579, doi. 10.1093/nar/gkv1122
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- Publication type:
- Article
A higher-order entity formed by the flexible assembly of RAP1 with TRF2.
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- Nucleic Acids Research, 2016, v. 44, n. 4, p. 1962, doi. 10.1093/nar/gkv1531
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- Publication type:
- Article
Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells.
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- Nature Communications, 2016, v. 7, n. 1, p. 10399, doi. 10.1038/ncomms10399
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- Article
TRF1 and TRF2 binding to telomeres is modulated by nucleosomal organization.
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- Nucleic Acids Research, 2015, v. 43, n. 12, p. 5824, doi. 10.1093/nar/gkv507
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- Article
A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.
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- Nucleic Acids Research, 2015, v. 43, n. 3, p. 1759, doi. 10.1093/nar/gkv006
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- Publication type:
- Article
The Wilms' tumour suppressor Wt1 is a major regulator of tumour angiogenesis and progression.
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- Nature Communications, 2014, v. 5, n. 12, p. 5852, doi. 10.1038/ncomms6852
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- Publication type:
- Article
The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells.
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- Nature Immunology, 2014, v. 15, n. 8, p. 749, doi. 10.1038/ni.2936
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- Article
Transcriptional outcome of telomere signalling.
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- Nature Reviews Genetics, 2014, v. 15, n. 7, p. 491, doi. 10.1038/nrg3743
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- Article
Length-dependent processing of telomeres in the absence of telomerase.
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- Nucleic Acids Research, 2014, v. 42, n. 6, p. 3648, doi. 10.1093/nar/gkt1328
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- Publication type:
- Article
Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis.
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- Nucleic Acids Research, 2014, v. 42, n. 5, p. 2945, doi. 10.1093/nar/gkt1289
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- Article
Telomeric impact of conventional chemotherapy.
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- Frontiers of Medicine, 2013, v. 7, n. 4, p. 411, doi. 10.1007/s11684-013-0293-z
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- Publication type:
- Article
Telomere protection and TRF2 expression are enhanced by the canonical Wnt signalling pathway.
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- EMBO Reports, 2013, v. 14, n. 4, p. 356, doi. 10.1038/embor.2013.16
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- Publication type:
- Article
One identity or more for telomeres?
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- Frontiers in Oncology, 2013, v. 3, p. 1, doi. 10.3389/fonc.2013.00048
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- Publication type:
- Article
A Snapshot of Histone Modifications within Transposable Elements in Drosophila Wild Type Strains.
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- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044253
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- Publication type:
- Article
HTLV-1 positive and negative T cells cloned from infected individuals display telomerase and telomere genes deregulation that predominate in activated but untransformed CD4+ T cells.
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- International Journal of Cancer, 2012, v. 131, n. 4, p. 821, doi. 10.1002/ijc.26270
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- Publication type:
- Article
RPA facilitates telomerase activity at chromosome ends in budding and fission yeasts.
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- EMBO Journal, 2012, v. 31, n. 8, p. 2034, doi. 10.1038/emboj.2012.40
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- Publication type:
- Article
TRF2 Controls Telomeric Nucleosome Organization in a Cell Cycle Phase-Dependent Manner.
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- PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034386
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- Publication type:
- Article
The N-terminal domains of TRF1 and TRF2 regulate their ability to condense telomeric DNA.
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- Nucleic Acids Research, 2012, v. 40, n. 6, p. 2566, doi. 10.1093/nar/gkr1116
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- Publication type:
- Article
The human TTAGGG repeat factors 1 and 2 bind to a subset of interstitial telomeric sequences and satellite repeats.
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- Cell Research, 2011, v. 21, n. 7, p. 1028, doi. 10.1038/cr.2011.40
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- Article
Structural identity of telomeric complexes
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- FEBS Letters, 2010, v. 584, n. 17, p. 3785, doi. 10.1016/j.febslet.2010.08.004
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- Article