Works by Gilsbach, Bernd K

Results: 10

Heterozygous RAB3A variants cause cerebellar ataxia by a partial loss-of-function mechanism.

Published in:

Brain: A Journal of Neurology, 2025, v. 148, n. 8, p. 2812, doi. 10.1093/brain/awaf111

By:

Hengel, Holger;
Hannan, Shabab B;
Reich, Selina;
Beijer, Danique;
Roller, Johanna;
Gilsbach, Bernd K;
Gloeckner, Christian Johannes;
Greene, Daniel;
Timmann, Dagmar;
Depienne, Christel;
Mumford, Andrew;
O'Driscoll, Mary;
Nemeth, Andrea H;
Lundberg, Julie;
Rodan, Lance H;
Bruel, Ange-Line;
Delanne, Julian;
Deconinck, Tine;
Baets, Jonathan;
Gan-Or, Ziv

Publication type:

Article

Structural biology of the LRRK2 GTPase and kinase domains: implications for regulation.

Published in:

Frontiers in Molecular Neuroscience, 2014, v. 7, p. 1, doi. 10.3389/fnmol.2014.00032

By:

Gilsbach, Bernd K.;
Kortholt, Arjan

Publication type:

Article

Structural biology of the LRRK2 GTPase and Kinase domains: Implications for regulation.

Published in:

Frontiers in Molecular Neuroscience, 2014, v. 7, p. 1, doi. 10.3389/fnmol.2014.00032

By:

Gilsbach, Bernd K.;
Kortholt, Arjan

Publication type:

Article

Revisiting the Roco G-protein cycle.

Published in:

Biochemical Journal, 2015, v. 465, n. 1, p. 139, doi. 10.1042/BJ20141095

By:

Terheyden, Susanne;
Hot, Franz Y.;
Gilsbach, Bernd K.;
Wittinghofer, Alfred;
Kortholt, Arjan

Publication type:

Article

C2GAP2 is a common regulator of Ras signaling for chemotaxis, phagocytosis, and macropinocytosis.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 01, doi. 10.3389/fimmu.2022.1075386

By:

Xuehua Xu;
Pots, Henderikus;
Gilsbach, Bernd K.;
Parsons, Dustin;
Veltman, Douwe M.;
Ramachandra, Sharmila G.;
Li, Haoran;
Kortholt, Arjan;
Tian Jin

Publication type:

Article

Conformational heterogeneity of the Roc domains in C. tepidum Roc–COR and implications for human LRRK2 Parkinson mutations.

Published in:

Bioscience Reports, 2015, v. 35, n. 5, p. 1, doi. 10.1042/BSR20150128

By:

Rudi, Katharina;
Ho, Franz Y.;
Gilsbach, Bernd K.;
Pots, Henderikus;
Wittinghofer, Alfred;
Kortholt, Arjan;
Klare, Johann P.

Publication type:

Article

Intramolecular feedback regulation of the LRRK2 Roc G domain by a LRRK2 kinase-dependent mechanism.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.91083

By:

Gilsbach, Bernd K.;
Ho, Franz Y.;
Riebenbauer, Benjamin;
Xiaojuan Zhang;
Guaitoli, Giambattista;
Kortholt, Arjan;
Gloeckner, Christian Johannes

Publication type:

Article

First model of dimeric LRRK2: the challenge of unrevealing the structure of a multidomain Parkinson's-associated protein.

Published in:

Biochemical Society Transactions, 2016, v. 44, n. 6, p. 1635, doi. 10.1042/BST20160226

By:

Guaitoli, Giambattista;
Gilsbach, Bernd K.;
Raimondi, Francesco;
Gloeckner, Christian Johannes

Publication type:

Article

Biochemical and kinetic properties of the complex Roco G-protein cycle.

Published in:

Biological Chemistry, 2018, v. 399, n. 12, p. 1447, doi. 10.1515/hsz-2018-0227

By:

Wauters, Lina;
Terheyden, Susanne;
Gilsbach, Bernd K.;
Leemans, Margaux;
Athanasopoulos, Panagiotis S.;
Guaitoli, Giambattista;
Wittinghofer, Alfred;
Gloeckner, Christian Johannes;
Versées, Wim;
Kortholt, Arjan

Publication type:

Article

Regulation of LRRK2: insights from structural and biochemical analysis.

Published in:

Biological Chemistry, 2018, v. 399, n. 7, p. 637, doi. 10.1515/hsz-2018-0132

By:

Gilsbach, Bernd K.;
Eckert, Marita;
Gloeckner, Christian Johannes

Publication type:

Article