Works by Gill, Dipender

Results: 138

Optimizing treatment of cardiovascular risk factors in cerebral small vessel disease using genetics.

Published in:

Brain: A Journal of Neurology, 2025, v. 148, n. 6, p. 1936, doi. 10.1093/brain/awae399

By:

Koohi, Fatemeh;
Harshfield, Eric L;
Gill, Dipender;
Ge, Wenjing;
Burgess, Stephen;
Markus, Hugh S

Publication type:

Article

Genetics of height and risk of atrial fibrillation: A Mendelian randomization study.

Published in:

2020

By:

Levin, Michael G.;
Judy, Renae;
Gill, Dipender;
Vujkovic, Marijana;
Verma, Shefali S.;
Bradford, Yuki;
Ritchie, Marylyn D.;
Hyman, Matthew C.;
Nazarian, Saman;
Rader, Daniel J.;
Voight, Benjamin F.;
Damrauer, Scott M.;
Regeneron Genetics Center

Publication type:

journal article

Robust use of phenotypic heterogeneity at drug target genes for mechanistic insights: Application of cis‐multivariable Mendelian randomization to GLP1R gene region.

Published in:

Genetic Epidemiology, 2024, v. 48, n. 4, p. 151, doi. 10.1002/gepi.22551

By:

Patel, Ashish;
Gill, Dipender;
Shungin, Dmitry;
Mantzoros, Christos S.;
Knudsen, Lotte Bjerre;
Bowden, Jack;
Burgess, Stephen

Publication type:

Article

Disentangling the effects of traits with shared clustered genetic predictors using multivariable Mendelian randomization.

Published in:

Genetic Epidemiology, 2022, v. 46, n. 7, p. 415, doi. 10.1002/gepi.22462

By:

Batool, Fatima;
Patel, Ashish;
Gill, Dipender;
Burgess, Stephen

Publication type:

Article

Novel loci and biomedical consequences of iron homoeostasis variation.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07115-3

By:

Allara, Elias;
Bell, Steven;
Smith, Rebecca;
Keene, Spencer J.;
Gill, Dipender;
Gaziano, Liam;
Morselli Gysi, Deisy;
Wang, Feiyi;
Tragante, Vinicius;
Mason, Amy;
Karthikeyan, Savita;
Lumbers, R. Thomas;
Bonglack, Emmanuela;
Ouwehand, Willem;
Roberts, David J.;
Dowsett, Joseph;
Ostrowski, Sisse Rye;
Larsen, Margit Hørup;
Ullum, Henrik;
Pedersen, Ole Birger

Publication type:

Article

Sparse dimensionality reduction approaches in Mendelian randomisation with highly correlated exposures.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.80063

By:

Karageorgiou, Vasileios;
Gill, Dipender;
Bowden, Jack;
Zuber, Verena

Publication type:

Article

Mendelian randomization study highlights the role of hematological traits on Type-2 diabetes mellitus in African ancestry individuals.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1436972

By:

Soremekun, Chisom;
Jjingo, Daudi;
Kateete, David;
Nash, Oyekanmi;
Nitsch, Dorothea;
Nyirenda, Moffat;
Gill, Dipender;
Zeggini, Eleftheria;
Grallert, Harald;
Peters, Annette;
Chikowore, Tinashe;
Batini, Chiara;
Soremekun, Opeyemi;
Fatumo, Segun

Publication type:

Article

Relative effects of genetically proxied glucagon‐like peptide‐1 receptor agonism on muscle and fat mass: A Mendelian randomization study.

Published in:

Diabetes, Obesity & Metabolism, 2025, v. 27, n. 4, p. 2280, doi. 10.1111/dom.16171

By:

Liang, Yiwen;
Luo, Shan;
Wan, Eric Yuk Fai;
Cheung, Ching Lung;
Gill, Dipender;
Au Yeung, Shiu Lun

Publication type:

Article

Network Mendelian randomisation analysis deciphers protein pathways linking type 2 diabetes and gastrointestinal disease.

Published in:

Diabetes, Obesity & Metabolism, 2025, v. 27, n. 2, p. 866, doi. 10.1111/dom.16087

By:

Geng, Jiawei;
Ruan, Xixian;
Wu, Xing;
Chen, Xuejie;
Fu, Tian;
Gill, Dipender;
Burgess, Stephen;
Chen, Jie;
Ludvigsson, Jonas F.;
Larsson, Susanna C.;
Li, Xue;
Du, Zhongyan;
Yuan, Shuai

Publication type:

Article

Effect of genetically predicted sclerostin on cardiovascular biomarkers, risk factors, and disease outcomes.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53623-5

By:

Alcalde-Herraiz, Marta;
Xie, JunQing;
Newby, Danielle;
Prats, Clara;
Gill, Dipender;
Gordillo-Marañón, María;
Prieto-Alhambra, Daniel;
Català, Martí;
Prats-Uribe, Albert

Publication type:

Article

Addressing the credibility crisis in Mendelian randomization.

Published in:

BMC Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12916-024-03607-5

By:

Burgess, Stephen;
Woolf, Benjamin;
Mason, Amy M.;
Ala-Korpela, Mika;
Gill, Dipender

Publication type:

Article

Genetic investigation into the broad health implications of caffeine: evidence from phenome-wide, proteome-wide and metabolome-wide Mendelian randomization.

Published in:

BMC Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12916-024-03298-y

By:

Zagkos, Loukas;
Cronjé, Héléne T.;
Woolf, Benjamin;
de La Harpe, Roxane;
Burgess, Stephen;
Mantzoros, Christos S.;
Elliott, Paul;
Yuan, Shuai;
Larsson, Susanna C.;
Tzoulaki, Ioanna;
Gill, Dipender

Publication type:

Article

The citrate transporter SLC13A5 as a therapeutic target for kidney disease: evidence from Mendelian randomization to inform drug development.

Published in:

BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-03227-5

By:

Gill, Dipender;
Zagkos, Loukas;
Gill, Rubinder;
Benzing, Thomas;
Jordan, Jens;
Birkenfeld, Andreas L.;
Burgess, Stephen;
Zahn, Grit

Publication type:

Article

Proteomic insights into the associations between obesity, lifestyle factors, and coronary artery disease.

Published in:

BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-03197-8

By:

Yang, Fangkun;
Xu, Fengzhe;
Zhang, Han;
Gill, Dipender;
Larsson, Susanna C.;
Li, Xue;
Cui, Hanbin;
Yuan, Shuai

Publication type:

Article

Appraising the causal relationship between plasma caffeine levels and neuropsychiatric disorders through Mendelian randomization.

Published in:

BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-03008-0

By:

Woolf, Benjamin;
Cronjé, Héléne T.;
Zagkos, Loukas;
Burgess, Stephen;
Gill, Dipender;
Larsson, Susanna C.

Publication type:

Article

Standardizing the reporting of Mendelian randomization studies.

Published in:

BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-02894-8

By:

Au Yeung, Shiu Lun;
Gill, Dipender

Publication type:

Article

Genetic evidence implicating natriuretic peptide receptor-3 in cardiovascular disease risk: a Mendelian randomization study.

Published in:

BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-02867-x

By:

Cronjé, Héléne T.;
Karhunen, Ville;
Hovingh, G. Kees;
Coppieters, Ken;
Lagerstedt, Jens O.;
Nyberg, Michael;
Gill, Dipender

Publication type:

Article

Cerebrospinal and Brain Proteins Implicated in Neuropsychiatric and Risk Factor Traits: Evidence from Mendelian Randomization.

Published in:

Biomedicines, 2024, v. 12, n. 2, p. 327, doi. 10.3390/biomedicines12020327

By:

de La Harpe, Roxane;
Zagkos, Loukas;
Gill, Dipender;
Cronjé, Héléne T.;
Karhunen, Ville

Publication type:

Article

Non‐genetic biomarkers and colorectal cancer risk: Umbrella review and evidence triangulation.

Published in:

Cancer Medicine, 2020, v. 9, n. 13, p. 4823, doi. 10.1002/cam4.3051

By:

Zhang, Xiaomeng;
Gill, Dipender;
He, Yazhou;
Yang, Tian;
Li, Xue;
Monori, Grace;
Campbell, Harry;
Dunlop, Malcolm;
Tsilidis, Konstantinos K.;
Timofeeva, Maria;
Theodoratou, Evropi

Publication type:

Article

A Mendelian randomization study of genetic liability to post-traumatic stress disorder and risk of ischemic stroke.

Published in:

Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02542-y

By:

Soremekun, Opeyemi;
Musanabaganwa, Clarisse;
Uwineza, Annette;
Ardissino, Maddalena;
Rajasundaram, Skanda;
Wani, Agaz H.;
Jansen, Stefan;
Mutabaruka, Jean;
Rutembesa, Eugene;
Soremekun, Chisom;
Cheickna, Cisse;
Wele, Mamadou;
Mugisha, Joseph;
Nash, Oyekanmi;
Kinyanda, Eugene;
Nitsch, Dorothea;
Fornage, Myriam;
Chikowore, Tinashe;
Gill, Dipender;
Wildman, Derek E.

Publication type:

Article

The mediating role of atrial fibrillation in causal associations between risk factors and stroke: a Mendelian randomization study.

Published in:

Epidemiology & Health, 2024, v. 46, p. 1, doi. 10.4178/epih.e2024005

By:

Shanmei Qin;
Mengmeng Wang;
Gill, Dipender;
Zhizhong Zhang;
Xinfeng Liu

Publication type:

Article

Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22338-2

By:

Pazoki, Raha;
Vujkovic, Marijana;
Elliott, Joshua;
Evangelou, Evangelos;
Gill, Dipender;
Ghanbari, Mohsen;
van der Most, Peter J.;
Pinto, Rui Climaco;
Wielscher, Matthias;
Farlik, Matthias;
Zuber, Verena;
de Knegt, Robert J.;
Snieder, Harold;
Uitterlinden, André G.;
Lifelines Cohort Study;
Boezen, H. Marike;
Franke, Lude;
van der Harst, Pim;
Navis, Gerjan;
Rots, Marianne

Publication type:

Article

Gastrointestinal Consequences of Type 2 Diabetes Mellitus and Impaired Glycemic Homeostasis: A Mendelian Randomization Study.

Published in:

Diabetes Care, 2023, v. 46, n. 4, p. 828, doi. 10.2337/dc22-1385

By:

Chen, Jie;
Yuan, Shuai;
Fu, Tian;
Ruan, Xixian;
Qiao, Jie;
Wang, Xiaoyan;
Li, Xue;
Gill, Dipender;
Burgess, Stephen;
Giovannucci, Edward L.;
Larsson, Susanna C.

Publication type:

Article

Polygenic Prediction of Type 2 Diabetes in Africa.

Published in:

2022

By:

Chikowore, Tinashe;
Ekoru, Kenneth;
Vujkovi, Marijana;
Gill, Dipender;
Pirie, Fraser;
Young, Elizabeth;
Sandhu, Manjinder S.;
McCarthy, Mark;
Rotimi, Charles;
Adeyemo, Adebowale;
Motala, Ayesha;
Fatumo, Segun

Publication type:

journal article

TIE1 and TEK signalling, intraocular pressure, and primary open-angle glaucoma: a Mendelian randomization study.

Published in:

Journal of Translational Medicine, 2023, p. 1, doi. 10.1186/s12967-023-04737-9

By:

Rajasundaram, Skanda;
Zebardast, Nazlee;
Mehta, Puja;
Khawaja, Anthony P.;
Warwick, Alasdair;
Duchinski, Katherine;
Burgess, Stephen;
Gill, Dipender;
Segrè, Ayellet V.;
Wiggs, Janey

Publication type:

Article

Genetically Predicted Midlife Blood Pressure and Coronary Artery Disease Risk: Mendelian Randomization Analysis.

Published in:

2020

By:

Gill, Dipender;
Georgakis, Marios K.;
Zuber, Verena;
Karhunen, Ville;
Burgess, Stephen;
Malik, Rainer;
Dichgans, Martin

Publication type:

journal article

Genetically Determined Uric Acid and the Risk of Cardiovascular and Neurovascular Diseases: A Mendelian Randomization Study of Outcomes Investigated in Randomized Trials.

Published in:

2019

By:

Efstathiadou, Anthoula;
Gill, Dipender;
McGrane, Frances;
Quinn, Terence;
Dawson, Jesse

Publication type:

journal article

Effects of Genetically Determined Iron Status on Risk of Venous Thromboembolism and Carotid Atherosclerotic Disease: A Mendelian Randomization Study.

Published in:

2019

By:

Gill, Dipender;
Brewer, Christopher F.;
Monori, Grace;
Trégouët, David-Alexandre;
Franceschini, Nora;
Giambartolomei, Claudia;
Tzoulaki, Ioanna;
Dehghan, Abbas;
INVENT Consortium

Publication type:

journal article

Association of Thyroid Function with Blood Pressure and Cardiovascular Disease: A Mendelian Randomization.

Published in:

Journal of Personalized Medicine, 2021, v. 11, n. 12, p. 1306, doi. 10.3390/jpm11121306

By:

Giontella, Alice;
Lotta, Luca A.;
Overton, John D.;
Baras, Aris;
Sartorio, Andrea;
Minuz, Pietro;
Gill, Dipender;
Melander, Olle;
Fava, Cristiano

Publication type:

Article

Laboratory sample turnaround times: do they cause delays in the ED?

Published in:

Journal of Evaluation in Clinical Practice, 2012, v. 18, n. 1, p. 121, doi. 10.1111/j.1365-2753.2010.01545.x

By:

Gill, Dipender;
Galvin, Sean;
Ponsford, Mark;
Bruce, David;
Reicher, John;
Preston, Laura;
Bernard, Stephani;
Lafferty, Jessica;
Robertson, Andrew;
Rose‐Morris, Anna;
Stoneham, Simon;
Rieu, Romelie;
Pooley, Sophie;
Weetch, Alison;
McCann, Lloyd

Publication type:

Article

Resting right ventricular function is associated with exercise performance in PAH, but not in CTEPH.

Published in:

European Heart Journal - Cardiovascular Imaging, 2018, v. 19, n. 2, p. 185, doi. 10.1093/ehjci/jex002

By:

Rehman, Michaela Beatrice;
Howard, Luke S.;
Christiaens, Luc P.;
Gill, Dipender;
Gibbs, J. Simon R.;
Nihoyannopoulos, Petros

Publication type:

Article

TwoStepCisMR: A Novel Method and R Package for Attenuating Bias in cis -Mendelian Randomization Analyses.

Published in:

Genes, 2022, v. 13, n. 9, p. 1541, doi. 10.3390/genes13091541

By:

Woolf, Benjamin;
Zagkos, Loukas;
Gill, Dipender

Publication type:

Article

Unravelling the Distinct Effects of Systolic and Diastolic Blood Pressure Using Mendelian Randomisation.

Published in:

Genes, 2022, v. 13, n. 7, p. 1226, doi. 10.3390/genes13071226

By:

Le, Nhu Ngoc;
Tran, Tran Q. B.;
Lip, Stefanie;
McCallum, Linsay;
McClure, John;
Dominiczak, Anna F.;
Gill, Dipender;
Padmanabhan, Sandosh

Publication type:

Article

Morning Cortisol and Circulating Inflammatory Cytokine Levels: A Mendelian Randomisation Study.

Published in:

Genes, 2022, v. 13, n. 1, p. 116, doi. 10.3390/genes13010116

By:

Rajasundaram, Skanda;
Rahman, Rezbieara P.;
Woolf, Benjamin;
Zhao, Sizheng Steven;
Gill, Dipender

Publication type:

Article

Sleep Disordered Breathing, Obesity and Atrial Fibrillation: A Mendelian Randomisation Study.

Published in:

Genes, 2022, v. 13, n. 1, p. 104, doi. 10.3390/genes13010104

By:

Ardissino, Maddalena;
Reddy, Rohin K.;
Slob, Eric A. W.;
Patel, Kiran H. K.;
Ryan, David K.;
Gill, Dipender;
Ng, Fu Siong

Publication type:

Article

Genetically Predicted Type 2 Diabetes Mellitus Liability, Glycated Hemoglobin and Cardiovascular Diseases: A Wide-Angled Mendelian Randomization Study.

Published in:

Genes, 2021, v. 12, n. 10, p. 1644, doi. 10.3390/genes12101644

By:

Liu, Bowen;
Mason, Amy M.;
Sun, Luanluan;
Di Angelantonio, Emanuele;
Gill, Dipender;
Burgess, Stephen

Publication type:

Article

Comparison of caffeine consumption behavior with plasma caffeine levels as exposure measures in drug-target mendelian randomization.

Published in:

American Journal of Epidemiology, 2024, v. 193, n. 12, p. 1776, doi. 10.1093/aje/kwae143

By:

Woolf, Benjamin;
Cronjé, Héléne T;
Zagkos, Loukas;
Larsson, Susanna C;
Gill, Dipender;
Burgess, Stephen

Publication type:

Article

Inconsistency in UK Biobank Event Definitions From Different Data Sources and Its Impact on Bias and Generalizability: A Case Study of Venous Thromboembolism.

Published in:

American Journal of Epidemiology, 2024, v. 193, n. 5, p. 787, doi. 10.1093/aje/kwad232

By:

Bassett, Emily;
Broadbent, James;
Gill, Dipender;
Burgess, Stephen;
Mason, Amy M

Publication type:

Article

Safety of beta-blocker and calcium channel blocker antihypertensive drugs in pregnancy: a Mendelian randomization study.

Published in:

2022

By:

Ardissino, Maddalena;
Slob, Eric A. W.;
Rajasundaram, Skanda;
Reddy, Rohin K.;
Woolf, Benjamin;
Girling, Joanna;
Johnson, Mark R.;
Ng, Fu Siong;
Gill, Dipender

Publication type:

journal article

Associations of genetically predicted IL-6 signaling with cardiovascular disease risk across population subgroups.

Published in:

2022

By:

Georgakis, Marios K.;
Malik, Rainer;
Richardson, Tom G.;
Howson, Joanna M. M.;
Anderson, Christopher D.;
Burgess, Stephen;
Hovingh, G. Kees;
Dichgans, Martin;
Gill, Dipender

Publication type:

journal article

Systematic review of Mendelian randomization studies on risk of cancer.

Published in:

2022

By:

Markozannes, Georgios;
Kanellopoulou, Afroditi;
Dimopoulou, Olympia;
Kosmidis, Dimitrios;
Zhang, Xiaomeng;
Wang, Lijuan;
Theodoratou, Evropi;
Gill, Dipender;
Burgess, Stephen;
Tsilidis, Konstantinos K.

Publication type:

journal article

Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis.

Published in:

2022

By:

Bouras, Emmanouil;
Karhunen, Ville;
Gill, Dipender;
Huang, Jian;
Haycock, Philip C;
Gunter, Marc J;
Johansson, Mattias;
Brennan, Paul;
Key, Tim;
Lewis, Sarah J;
Martin, Richard M;
Murphy, Neil;
Platz, Elizabeth A;
Travis, Ruth;
Yarmolinsky, James;
Zuber, Verena;
Martin, Paul;
Katsoulis, Michail;
Freisling, Heinz;
Nøst, Therese Haugdahl

Publication type:

journal article

The diagnostic conundrum of primary angiitis of the central nervous system: a case report.

Published in:

2011

By:

Gill, Dipender;
Hinze, Stephan;
Palace, Jacqueline

Publication type:

Letter

The effect of statins on severity of psoriasis: A systematic review.

Published in:

2017

By:

Ramessur, Ravi;
Gill, Dipender

Publication type:

journal article

Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03529-z

By:

Moksnes, Marta R.;
Graham, Sarah E.;
Wu, Kuan-Han;
Hansen, Ailin Falkmo;
Gagliano Taliun, Sarah A.;
Zhou, Wei;
Thorstensen, Ketil;
Fritsche, Lars G.;
Gill, Dipender;
Mason, Amy;
Cucca, Francesco;
Schlessinger, David;
Abecasis, Gonçalo R.;
Burgess, Stephen;
Åsvold, Bjørn Olav;
Nielsen, Jonas B.;
Hveem, Kristian;
Willer, Cristen J.;
Brumpton, Ben M.

Publication type:

Article

Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03529-z

By:

Moksnes, Marta R.;
Graham, Sarah E.;
Wu, Kuan-Han;
Hansen, Ailin Falkmo;
Gagliano Taliun, Sarah A.;
Zhou, Wei;
Thorstensen, Ketil;
Fritsche, Lars G.;
Gill, Dipender;
Mason, Amy;
Cucca, Francesco;
Schlessinger, David;
Abecasis, Gonçalo R.;
Burgess, Stephen;
Åsvold, Bjørn Olav;
Nielsen, Jonas B.;
Hveem, Kristian;
Willer, Cristen J.;
Brumpton, Ben M.

Publication type:

Article

A case series of vaccine‐induced thrombotic thrombocytopenia in a London teaching hospital.

Published in:

British Journal of Clinical Pharmacology, 2022, v. 88, n. 4, p. 1935, doi. 10.1111/bcp.15116

By:

Watts, Isabella;
Smith, David;
Mounter, Sarah;
Baker, Emma H.;
Hitchings, Andrew W.;
Gill, Dipender

Publication type:

Article

Leveraging genetic data to investigate the effects of interleukin‐6 receptor signalling on levels of 40 circulating cytokines.

Published in:

British Journal of Clinical Pharmacology, 2022, v. 88, n. 3, p. 1373, doi. 10.1111/bcp.15079

By:

Rahman, Rezbieara P.;
McEwan, Lauren;
Ryan, David K.;
Gill, Dipender

Publication type:

Article

Low‐density lipoprotein cholesterol and lifespan: A Mendelian randomization study.

Published in:

British Journal of Clinical Pharmacology, 2021, v. 87, n. 10, p. 3916, doi. 10.1111/bcp.14811

By:

Daghlas, Iyas;
Gill, Dipender

Publication type:

Article

Genetically proxied growth‐differentiation factor 15 levels and body mass index.

Published in:

British Journal of Clinical Pharmacology, 2021, v. 87, n. 10, p. 4036, doi. 10.1111/bcp.14808

By:

Karhunen, Ville;
Larsson, Susanna C.;
Gill, Dipender

Publication type:

Article