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Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30875-7
By:
- Cadby, Gemma;
- Giles, Corey;
- Melton, Phillip E.;
- Huynh, Kevin;
- Mellett, Natalie A.;
- Duong, Thy;
- Nguyen, Anh;
- Cinel, Michelle;
- Smith, Alex;
- Olshansky, Gavriel;
- Wang, Tingting;
- Brozynska, Marta;
- Inouye, Mike;
- McCarthy, Nina S.;
- Ariff, Amir;
- Hung, Joseph;
- Hui, Jennie;
- Beilby, John;
- Dubé, Marie-Pierre;
- Watts, Gerald F.
Publication type:
Article
APOE ε2 resilience for Alzheimer's disease is mediated by plasma lipid species: Analysis of three independent cohort studies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 11, p. 2151, doi. 10.1002/alz.12538
By:
- Wang, Tingting;
- Huynh, Kevin;
- Giles, Corey;
- Mellett, Natalie A;
- Duong, Thy;
- Nguyen, Anh;
- Lim, Wei Ling Florence;
- Smith, Alex AT;
- Olshansky, Gavriel;
- Cadby, Gemma;
- Hung, Joseph;
- Hui, Jennie;
- Beilby, John;
- Watts, Gerald F;
- Chatterjee, Pratishtha;
- Martins, Ian;
- Laws, Simon M;
- Bush, Ashley I;
- Rowe, Christopher C;
- Villemagne, Victor L
Publication type:
Article
Lipidomic signatures for APOE genotypes provides new insights about mechanisms of resilience in Alzheimer’s disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056703
By:
- Wang, Tingting;
- Huynh, Kevin;
- Giles, Corey;
- Lim, Wei Ling Florence;
- Duong, Thy;
- Mellett, Natalie A.;
- Smith, Alexander;
- Olshansky, Gavriel;
- Drew, Brian G.;
- Cadby, Gemma;
- Melton, Phillip E.;
- Hung, Joseph;
- Beilby, John;
- Watts, Gerald F.;
- Chatterjee, Pratishtha;
- Martins, Ian;
- Laws, Simon M.;
- Bush, Ashley I.;
- Rowe, Christopher C.;
- Villemagne, Victor L.
Publication type:
Article
Genome‐wide study of the human lipidome and links to Alzheimer's disease risk: Genome‐metabolome‐phenome: Towards an integrated molecular atlas for Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045600
By:
- Meikle, Peter J.;
- Giles, Corey;
- Cadby, Gemma;
- Huynh, Kevin;
- Mellett, Natalie A.;
- Olshansky, Gavriel;
- Smith, Alexander;
- Nguyen, Anh;
- Chatterjee, Pratishtha;
- Martins, Ian;
- Laws, Simon M.;
- Bush, Ashley I.;
- Rowe, Christopher C.;
- Villemagne, Victor L.L.;
- Ames, David;
- Masters, Colin L.;
- Arnold, Matthias;
- Kastenmüller, Gabi;
- Nho, Kwangsik;
- Saykin, Andrew J.
Publication type:
Article
Identification of concordant plasma lipid signatures in Alzheimer's disease: Validation between two independent studies of Alzheimer's disease: Biomarkers (non‐neuroimaging): Novel biomarkers.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042275
By:
- Huynh, Kevin;
- Lim, Wei Ling Florence;
- Giles, Corey;
- Jayawardana, Kaushala S;
- Salim, Agus;
- Mellett, Natalie A;
- Smith, Alexander;
- Olshansky, Gavriel;
- Drew, Brian G;
- Chatterjee, Pratishtha;
- Martins, Ian;
- Laws, Simon M;
- Bush, Ashley I;
- Rowe, Christopher C;
- Villemagne, Victor LL;
- Ames, David;
- Masters, Colin L;
- Arnold, Matthias;
- Nho, Kwangsik;
- Saykin, Andrew J.
Publication type:
Article
Mapping the Associations of the Plasma Lipidome With Insulin Resistance and Response to an Oral Glucose Tolerance Test.
Published in:
2020
By:
- Beyene, Habtamu B;
- Hamley, Steven;
- Giles, Corey;
- Huynh, Kevin;
- Smith, Alexander;
- Cinel, Michelle;
- Mellet, Natalie A;
- Morales-Scholz, Maria G;
- Kloosterman, Danielle;
- Howlett, Kirsten F;
- Kowalski, Greg M;
- Shaw, Christopher S;
- Magliano, Dianna J;
- Bruce, Clinton R;
- Meikle, Peter J
Publication type:
journal article
High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two large population cohort studies.
Published in:
PLoS Biology, 2020, v. 18, n. 9, p. 1, doi. 10.1371/journal.pbio.3000870
By:
- Beyene, Habtamu B.;
- Olshansky, Gavriel;
- T. Smith, Adam Alexander;
- Giles, Corey;
- Huynh, Kevin;
- Cinel, Michelle;
- Mellett, Natalie A.;
- Cadby, Gemma;
- Hung, Joseph;
- Hui, Jennie;
- Beilby, John;
- Watts, Gerald F.;
- Shaw, Jonathan S.;
- Moses, Eric K.;
- Magliano, Dianna J.;
- Meikle, Peter J.
Publication type:
Article
Lipidomic Signatures of Changes in Adiposity: A Large Prospective Study of 5849 Adults from the Australian Diabetes, Obesity and Lifestyle Study.
Published in:
Metabolites (2218-1989), 2021, v. 11, n. 9, p. 646, doi. 10.3390/metabo11090646
By:
- Beyene, Habtamu B.;
- Olshansky, Gavriel;
- Giles, Corey;
- Huynh, Kevin;
- Cinel, Michelle;
- Mellett, Natalie A.;
- Smith, Adam Alexander T.;
- Shaw, Jonathan E.;
- Magliano, Dianna J.;
- Meikle, Peter J.
Publication type:
Article
The Impact of Simvastatin on Lipidomic Markers of Cardiovascular Risk in Human Liver Cells Is Secondary to the Modulation of Intracellular Cholesterol.
Published in:
Metabolites (2218-1989), 2021, v. 11, n. 6, p. 340, doi. 10.3390/metabo11060340
By:
- Schooneveldt, Yvette L.;
- Giles, Corey;
- Keating, Michael F.;
- Mellett, Natalie A.;
- Jurrjens, Aaron W.;
- Paul, Sudip;
- Calkin, Anna C.;
- Meikle, Peter J.
Publication type:
Article
Plasma Docosahexaenoic Acid and Eicosapentaenoic Acid Concentrations Are Positively Associated with Brown Adipose Tissue Activity in Humans.
Published in:
Metabolites (2218-1989), 2020, v. 10, n. 10, p. 388, doi. 10.3390/metabo10100388
By:
- Xiang, Angie S.;
- Giles, Corey;
- Loh, Rebecca K.C.;
- Formosa, Melissa F.;
- Eikelis, Nina;
- Lambert, Gavin W.;
- Meikle, Peter J.;
- Kingwell, Bronwyn A.;
- Carey, Andrew L.
Publication type:
Article
The serum concentration of the calcium binding protein S100B is positively associated with cognitive performance in older adults.
Published in:
Frontiers in Aging Neuroscience, 2013, v. 5, p. 1, doi. 10.3389/fnagi.2013.00061
By:
- Lam, Virginie;
- Albrecht, Matthew A.;
- Takechi, Ryusuke;
- Giles, Corey;
- James, Anthony P.;
- Foster, Jonathan K.;
- Mamo, John C. L.
Publication type:
Article
Imputation of plasma lipid species to facilitate integration of lipidomic datasets.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45838-3
By:
- Dakic, Aleksandar;
- Wu, Jingqin;
- Wang, Tingting;
- Huynh, Kevin;
- Mellett, Natalie;
- Duong, Thy;
- Beyene, Habtamu B.;
- Magliano, Dianna J.;
- Shaw, Jonathan E.;
- Carrington, Melinda J.;
- Inouye, Michael;
- Yang, Jean Y.;
- Figtree, Gemma A.;
- Curran, Joanne E.;
- Blangero, John;
- Simes, John;
- LIPID Study Investigators;
- Giles, Corey;
- Meikle, Peter J.
Publication type:
Article
Metabolic phenotyping of BMI to characterize cardiometabolic risk: evidence from large population-based cohorts.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41963-7
By:
- Beyene, Habtamu B.;
- Giles, Corey;
- Huynh, Kevin;
- Wang, Tingting;
- Cinel, Michelle;
- Mellett, Natalie A.;
- Olshansky, Gavriel;
- Meikle, Thomas G.;
- Watts, Gerald F.;
- Hung, Joseph;
- Hui, Jennie;
- Cadby, Gemma;
- Beilby, John;
- Blangero, John;
- Moses, Eric K.;
- Shaw, Jonathan E.;
- Magliano, Dianna J.;
- Meikle, Peter J.
Publication type:
Article
Metabolic phenotyping of BMI to characterize cardiometabolic risk: evidence from large population-based cohorts.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41963-7
By:
- Beyene, Habtamu B.;
- Giles, Corey;
- Huynh, Kevin;
- Wang, Tingting;
- Cinel, Michelle;
- Mellett, Natalie A.;
- Olshansky, Gavriel;
- Meikle, Thomas G.;
- Watts, Gerald F.;
- Hung, Joseph;
- Hui, Jennie;
- Cadby, Gemma;
- Beilby, John;
- Blangero, John;
- Moses, Eric K.;
- Shaw, Jonathan E.;
- Magliano, Dianna J.;
- Meikle, Peter J.
Publication type:
Article
The Vitamin D, Ionised Calcium and Parathyroid Hormone Axis of Cerebral Capillary Function: Therapeutic Considerations for Vascular-Based Neurodegenerative Disorders.
Published in:
PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0125504
By:
- Lam, Virginie;
- Takechi, Ryusuke;
- Pallabage-Gamarallage, Menuka;
- Giles, Corey;
- Mamo, John C. L.
Publication type:
Article
Ontogeny of circulating lipid metabolism in pregnancy and early childhood -- a longitudinal population study.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.72779
By:
- Burugupalli, Satvika;
- Smith, Adam Alexander T.;
- Oshlensky, Gavriel;
- Huynh, Kevin;
- Giles, Corey;
- Wang, Tingting;
- George, Alexandra;
- Paul, Sudip;
- Anh Nguyen;
- Thy Duong;
- Mellett, Natalie;
- Cinel, Michelle;
- Mir, Sartaj Ahmad;
- Li Chen;
- Wenk, Markus R.;
- Karnani, Neerja;
- Collier, Fiona;
- Saffery, Richard;
- Vuillermin, Peter;
- Ponsonby, Anne- Louise
Publication type:
Article
Lipidomics Profiling and Risk of Coronary Artery Disease in the BioHEART-CT Discovery Cohort.
Published in:
Biomolecules (2218-273X), 2023, v. 13, n. 6, p. 917, doi. 10.3390/biom13060917
By:
- Zhu, Dantong;
- Vernon, Stephen T.;
- D'Agostino, Zac;
- Wu, Jingqin;
- Giles, Corey;
- Chan, Adam S.;
- Kott, Katharine A.;
- Gray, Michael P.;
- Gholipour, Alireza;
- Tang, Owen;
- Beyene, Habtamu B.;
- Patrick, Ellis;
- Grieve, Stuart M.;
- Meikle, Peter J.;
- Figtree, Gemma A.;
- Yang, Jean Y. H.
Publication type:
Article
Population-based plasma lipidomics reveals developmental changes in metabolism and signatures of obesity risk: a mother-offspring cohort study.
Published in:
2022
By:
- Mir, Sartaj Ahmad;
- Chen, Li;
- Burugupalli, Satvika;
- Burla, Bo;
- Ji, Shanshan;
- Smith, Adam Alexander T.;
- Narasimhan, Kothandaraman;
- Ramasamy, Adaikalavan;
- Tan, Karen Mei-Ling;
- Huynh, Kevin;
- Giles, Corey;
- Mei, Ding;
- Wong, Gerard;
- Yap, Fabian;
- Tan, Kok Hian;
- Collier, Fiona;
- Saffery, Richard;
- Vuillermin, Peter;
- Bendt, Anne K.;
- Burgner, David
Publication type:
journal article
Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment.
Published in:
Immunity & Ageing, 2015, v. 12, n. 1, p. 1, doi. 10.1186/s12979-015-0029-9
By:
- Elahy, Mina;
- Jackaman, Connie;
- Mamo, John C. L.;
- Lam, Virginie;
- Dhaliwal, Satvinder S.;
- Giles, Corey;
- Nelson, Delia;
- Takechi, Ryusuke
Publication type:
Article
Correction: High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two large population cohort studies.
Published in:
2020
By:
- Beyene, Habtamu B.;
- Olshansky, Gavriel;
- T. Smith, Adam Alexander;
- Giles, Corey;
- Huynh, Kevin;
- Cinel, Michelle;
- Mellett, Natalie A.;
- Cadby, Gemma;
- Hung, Joseph;
- Hui, Jennie;
- Beilby, John;
- Watts, Gerald F.;
- Shaw, Jonathan E.;
- Moses, Eric K.;
- Magliano, Dianna J.;
- Meikle, Peter J.
Publication type:
Correction Notice
Differential regulation of sphingolipid metabolism in plasma, hippocampus, and cerebral cortex of mice administered sphingolipid modulating agents.
Published in:
Journal of Neurochemistry, 2017, v. 141, n. 3, p. 413, doi. 10.1111/jnc.13964
By:
- Giles, Corey;
- Takechi, Ryusuke;
- Mellett, Natalie A.;
- Meikle, Peter J.;
- Dhaliwal, Satvinder;
- Mamo, John C.
Publication type:
Article
Long-term probucol therapy continues to suppress markers of neurovascular inflammation in a dietary induced model of cerebral capillary dysfunction.
Published in:
Lipids in Health & Disease, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1476-511X-13-91
By:
- Takechi, Ryusuke;
- Pallebage-Gamarallage, Menuka M.;
- Lam, Virginie;
- Giles, Corey;
- Mamo, John C. L.
Publication type:
Article
The effect of diesel exhaust exposure on blood-brain barrier integrity and function in a murine model.
Published in:
Journal of Applied Toxicology, 2015, v. 35, n. 1, p. 41, doi. 10.1002/jat.2985
By:
- Heidari Nejad, Sayeh;
- Takechi, Ryusuke;
- Mullins, Benjamin J.;
- Giles, Corey;
- Larcombe, Alexander N.;
- Bertolatti, Dean;
- Rumchev, Krassi;
- Dhaliwal, Satvinder;
- Mamo, John
Publication type:
Article
The potential of integrating human and mouse discovery platforms to advance our understanding of cardiometabolic diseases.
Published in:
eLife, 2023, p. 1, doi. 10.7554/eLife.86139
By:
- Jurrjens, Aaron W.;
- Seldin, Marcus M.;
- Giles, Corey;
- Meikle, Peter J.;
- Drew, Brian G.;
- Calkin, Anna C.
Publication type:
Article
HDL Phospholipids, but Not Cholesterol Distinguish Acute Coronary Syndrome From Stable Coronary Artery Disease.
Published in:
2019
By:
- Meikle, Peter J.;
- Formosa, Melissa F.;
- Mellett, Natalie A.;
- Jayawardana, Kaushala S.;
- Giles, Corey;
- Bertovic, David A.;
- Jennings, Garry L.;
- Childs, Wayne;
- Reddy, Medini;
- Carey, Andrew L.;
- Baradi, Arul;
- Nanayakkara, Shane;
- Wilson, Andrew M.;
- Duffy, Stephen J.;
- Kingwell, Bronwyn A.
Publication type:
journal article
The Effects of Long-Term Saturated Fat Enriched Diets on the Brain Lipidome.
Published in:
PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0166964
By:
- Giles, Corey;
- Takechi, Ryusuke;
- Mellett, Natalie A.;
- Meikle, Peter J.;
- Dhaliwal, Satvinder;
- Mamo, John C.
Publication type:
Article
Nutraceutical agents with anti-inflammatory properties prevent dietary saturated-fat induced disturbances in blood–brain barrier function in wild-type mice.
Published in:
Journal of Neuroinflammation, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-2094-10-73
By:
- Takechi, Ryusuke;
- Pallebage-Gamarallage, Menuka M.;
- Lam, Virginie;
- Giles, Corey;
- Mamo, John C.
Publication type:
Article
Nutraceutical agents with anti-inflammatory properties prevent dietary saturated-fat induced disturbances in blood-brain barrier function in wild-type mice.
Published in:
2013
By:
- Takechi, Ryusuke;
- Pallebage-Gamarallage, Menuka M;
- Lam, Virginie;
- Giles, Corey;
- Mamo, John C
Publication type:
journal article
Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer's disease.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19473-7
By:
- Huynh, Kevin;
- Lim, Wei Ling Florence;
- Giles, Corey;
- Jayawardana, Kaushala S.;
- Salim, Agus;
- Mellett, Natalie A.;
- Smith, Adam Alexander T.;
- Olshansky, Gavriel;
- Drew, Brian G.;
- Chatterjee, Pratishtha;
- Martins, Ian;
- Laws, Simon M.;
- Bush, Ashley I.;
- Rowe, Christopher C.;
- Villemagne, Victor L.;
- Ames, David;
- Masters, Colin L.;
- Arnold, Matthias;
- Nho, Kwangsik;
- Saykin, Andrew J.
Publication type:
Article
Nicotine Attenuates Disruption of Blood-Brain Barrier Induced by Saturated-Fat Feeding in Wild-Type Mice.
Published in:
2015
By:
- Elahy, Mina;
- Lam, Virginie;
- Pallebage-Gamarallage, Menuka M.;
- Giles, Corey;
- Mamo, John C. L.;
- Takechi, Ryusuke
Publication type:
journal article
Novel Lipid Species for Detecting and Predicting Atrial Fibrillation in Patients With Type 2 Diabetes.
Published in:
2021
By:
- Tham, Yow Keat;
- Jayawardana, Kaushala S.;
- Alshehry, Zahir H.;
- Giles, Corey;
- Huynh, Kevin;
- Smith, Adam Alexander T.;
- Ooi, Jenny Y.Y.;
- Zoungas, Sophia;
- Hillis, Graham S.;
- Chalmers, John;
- Meikle, Peter J.;
- McMullen, Julie R.
Publication type:
journal article

Found: 31