Works by Gilep, Andrei A.

Results: 20

Human Lanosterol 14-Alpha Demethylase (CYP51A1) Is a Putative Target for Natural Flavonoid Luteolin 7,3′-Disulfate.

Published in:

Molecules, 2021, v. 26, n. 8, p. 2237, doi. 10.3390/molecules26082237

By:

Kaluzhskiy, Leonid;
Ershov, Pavel;
Yablokov, Evgeniy;
Shkel, Tatsiana;
Grabovec, Irina;
Mezentsev, Yuri;
Gnedenko, Oksana;
Usanov, Sergey;
Shabunya, Polina;
Fatykhava, Sviatlana;
Popov, Alexander;
Artyukov, Aleksandr;
Styshova, Olga;
Gilep, Andrei;
Strushkevich, Natallia;
Ivanov, Alexis

Publication type:

Article

Bielectrode Strategy for Determination of CYP2E1 Catalytic Activity: Electrodes with Bactosomes and Voltammetric Determination of 6-Hydroxychlorzoxazone.

Published in:

Biomedicines, 2024, v. 12, n. 1, p. 152, doi. 10.3390/biomedicines12010152

By:

Kuzikov, Alexey V.;
Masamrekh, Rami A.;
Filippova, Tatiana A.;
Tumilovich, Anastasiya M.;
Strushkevich, Natallia V.;
Gilep, Andrei A.;
Khudoklinova, Yulia Yu.;
Shumyantseva, Victoria V.

Publication type:

Article

Molecular Cloning, Heterologous Expression, Purification, and Evaluation of Protein–Ligand Interactions of CYP51 of Candida krusei Azole-Resistant Fungal Strain.

Published in:

Biomedicines, 2023, v. 11, n. 11, p. 2873, doi. 10.3390/biomedicines11112873

By:

Tsybruk, Tatsiana V.;
Kaluzhskiy, Leonid A.;
Mezentsev, Yuri V.;
Makarieva, Tatyana N.;
Tabakmaher, Kseniya M.;
Ivanchina, Natalia V.;
Dmitrenok, Pavel S.;
Baranovsky, Alexander V.;
Gilep, Andrei A.;
Ivanov, Alexis S.

Publication type:

Article

Human steroid and oxysterol 7α-hydroxylase CYP7B1: substrate specificity, azole binding and misfolding of clinically relevant mutants.

Published in:

FEBS Journal, 2014, v. 281, n. 6, p. 1700, doi. 10.1111/febs.12733

By:

Yantsevich, Aleksei V.;
Dichenko, Yaroslav V.;
MacKenzie, Farrell;
Mukha, Dmitry V.;
Baranovsky, Alexander V.;
Gilep, Andrei A.;
Usanov, Sergey A.;
Strushkevich, Natallia V.

Publication type:

Article

Combining of synthetic VHH and immune scFv libraries for pregnancy-associated glycoproteins ELISA development.

Published in:

Applied Microbiology & Biotechnology, 2022, v. 106, n. 13-16, p. 5093, doi. 10.1007/s00253-022-12022-w

By:

Dormeshkin, Dmitri;
Shapira, Michail;
Karputs, Alena;
Kavaleuski, Anton;
Kuzminski, Ivan;
Stepanova, Elena;
Gilep, Andrei

Publication type:

Article

A new insight into subinteractomes of functional antagonists: Thromboxane (CYP5A1) and prostacyclin (CYP8A1) synthases.

Published in:

Cell Biology International, 2021, v. 45, n. 6, p. 1175, doi. 10.1002/cbin.11564

By:

Ershov, Pavel V.;
Yablokov, Evgeniy;
Zgoda, Victor;
Mezentsev, Yuri;
Gnedenko, Oksana;
Kaluzhskiy, Leonid;
Svirid, Andrey;
Gilep, Andrei;
Usanov, Sergey A.;
Ivanov, Alexis

Publication type:

Article

Human Cytochrome P450 2C9 and Its Polymorphic Modifications: Electroanalysis, Catalytic Properties, and Approaches to the Regulation of Enzymatic Activity.

Published in:

Processes, 2022, v. 10, n. 2, p. 383, doi. 10.3390/pr10020383

By:

Shumyantseva, Victoria V.;
Bulko, Tatiana V.;
Koroleva, Polina I.;
Shikh, Evgeniya V.;
Makhova, Anna A.;
Kisel, Maryia S.;
Haidukevich, Irina V.;
Gilep, Andrei A.

Publication type:

Article

Affinity Isolation and Mass Spectrometry Identification of Prostacyclin Synthase (PTGIS) Subinteractome.

Published in:

Biology (2079-7737), 2019, v. 8, n. 2, p. 49, doi. 10.3390/biology8020049

By:

Ershov, Pavel V.;
Mezentsev, Yuri V.;
Kopylov, Arthur T.;
Yablokov, Evgeniy O.;
Svirid, Andrey V.;
Lushchyk, Aliaksandr Ya.;
Kaluzhskiy, Leonid A.;
Gilep, Andrei A.;
Usanov, Sergey A.;
Medvedev, Alexey E.;
Ivanov, Alexis S.

Publication type:

Article

Improving the Efficiency of Electrocatalysis of Cytochrome P450 3A4 by Modifying the Electrode with Membrane Protein Streptolysin O for Studying the Metabolic Transformations of Drugs.

Published in:

Biosensors (2079-6374), 2023, v. 13, n. 4, p. 457, doi. 10.3390/bios13040457

By:

Koroleva, Polina I.;
Gilep, Andrei A.;
Kraevsky, Sergey V.;
Tsybruk, Tatiana V.;
Shumyantseva, Victoria V.

Publication type:

Article

PharmVar GeneFocus: CYP3A5.

Published in:

Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1159, doi. 10.1002/cpt.2563

By:

Rodriguez‐Antona, Cristina;
Savieo, Jessica L.;
Lauschke, Volker M.;
Sangkuhl, Katrin;
Drögemöller, Britt I.;
Wang, Danxin;
van Schaik, Ron H. N.;
Gilep, Andrei A.;
Peter, Arul P.;
Boone, Erin C.;
Ramey, Bronwyn E.;
Klein, Teri E.;
Whirl‐Carrillo, Michelle;
Pratt, Victoria M.;
Gaedigk, Andrea

Publication type:

Article

Role Assessment of Water-Soluble Pharmaceutical Form of Phosphatidylcholine on the Catalytic Activity of Cytochrome P450 2C9 and 2D6.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 1, p. 4, doi. 10.3390/ijms26010004

By:

Koroleva, Polina I.;
Bulko, Tatiana V.;
Kuzikov, Alexey V.;
Gilep, Andrei A.;
Romashova, Yulia A.;
Tichonova, Elena G.;
Kostrukova, Lyubov V.;
Archakov, Alexander I.;
Shumyantseva, Victoria V.

Publication type:

Article

The Multienzyme Complex Nature of Dehydroepiandrosterone Sulfate Biosynthesis.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 4, p. 2072, doi. 10.3390/ijms25042072

By:

Tumilovich, Anastasiya;
Yablokov, Evgeniy;
Mezentsev, Yuri;
Ershov, Pavel;
Basina, Viktoriia;
Gnedenko, Oksana;
Kaluzhskiy, Leonid;
Tsybruk, Tatsiana;
Grabovec, Irina;
Kisel, Maryia;
Shabunya, Polina;
Soloveva, Natalia;
Vavilov, Nikita;
Gilep, Andrei;
Ivanov, Alexis

Publication type:

Article

Hydroxylation of Antitubercular Drug Candidate, SQ109, by Mycobacterial Cytochrome P450.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 20, p. 7683, doi. 10.3390/ijms21207683

By:

Bukhdruker, Sergey;
Varaksa, Tatsiana;
Grabovec, Irina;
Marin, Egor;
Shabunya, Polina;
Kadukova, Maria;
Grudinin, Sergei;
Kavaleuski, Anton;
Gusach, Anastasiia;
Gilep, Andrei;
Borshchevskiy, Valentin;
Strushkevich, Natallia

Publication type:

Article

Mechanism of the Affinity-Enhancing Effect of Isatin on Human Ferrochelatase and Adrenodoxin Reductase Complex Formation: Implication for Protein Interactome Regulation.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 20, p. 7605, doi. 10.3390/ijms21207605

By:

Ershov, Pavel V.;
Veselovsky, Alexander V.;
Mezentsev, Yuri V.;
Yablokov, Evgeniy O.;
Kaluzhskiy, Leonid A.;
Tumilovich, Anastasiya M.;
Kavaleuski, Anton A.;
Gilep, Andrei A.;
Moskovkina, Taisiya V.;
Medvedev, Alexei E.;
Ivanov, Alexis S.

Publication type:

Article

No effect of lipoic acid on catalytic activity of cytochrome P450 3A4.

Published in:

Drug Metabolism & Personalized Therapy, 2020, v. 35, n. 3, p. 1, doi. 10.1515/dmpt-2020-0105

By:

Makhova, Anna A.;
Shikh, Evgeniya V.;
Bulko, Tatiana V.;
Gilep, Andrei A.;
Usanov, Sergei A.;
Shumyantseva, Victoria V.

Publication type:

Article

Structural insights into the effects of glycerol on ligand binding to cytochrome P450.

Published in:

Acta Crystallographica: Section D, Structural Biology, 2023, v. 79, n. 1, p. 66, doi. 10.1107/S2059798322011019

By:

Bukhdruker, Sergey;
Varaksa, Tatsiana;
Orekhov, Philipp;
Grabovec, Irina;
Marin, Egor;
Kapranov, Ivan;
Kovalev, Kirill;
Astashkin, Roman;
Kaluzhskiy, Leonid;
Ivanov, Alexis;
Mishin, Alexey;
Rogachev, Andrey;
Gordeliy, Valentin;
Gilep, Andrei;
Strushkevich, Natallia;
Borshchevskiy, Valentin

Publication type:

Article

In vitro interactions of abiraterone, erythromycin, and CYP3A4: implications for drug–drug interactions.

Published in:

Fundamental & Clinical Pharmacology, 2020, v. 34, n. 1, p. 120, doi. 10.1111/fcp.12497

By:

Masamrekh, Rami A.;
Kuzikov, Alexey V.;
Haurychenka, Yaraslau I.;
Shcherbakov, Kirill A.;
Veselovsky, Alexander V.;
Filimonov, Dmitrii A.;
Dmitriev, Alexander V.;
Zavialova, Maria G.;
Gilep, Andrei A.;
Shkel, Tatsiana V.;
Strushkevich, Natallia V.;
Usanov, Sergey A.;
Archakov, Alexander I.;
Shumyantseva, Victoria V.

Publication type:

Article

Molecular identification of adrenal inner zone antigen as a heme-binding protein.

Published in:

FEBS Journal, 2005, v. 272, n. 22, p. 5832, doi. 10.1111/j.1742-4658.2005.04977.x

By:

Li Min;
Strushkevich, Natallia V.;
Harnastai, Ivan N.;
Iwamoto, Hiroko;
Gilep, Andrei A.;
Takemori, Hiroshi;
Usanov, Sergey A.;
Nonaka, Yasuki;
Hori, Hiroshi;
Vinson, Gavin P.;
Okamoto, Mitsuhiro

Publication type:

Article

The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450-mediated biotransformation (a corrigendum report on Duarte et al. (2005) Mutagenesis 20, 93–100)

Published in:

Mutagenesis, 2007, v. 22, n. 1, p. 75

By:

Maria Paula Duarte;
Bernardo Brito Palma;
Andrei A. Gilep;
António Laires;
José Santos Oliveira;
Sergey A. Usanov;
José Rueff;
Michel Kranendonk

Publication type:

Article

The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450 mediated biotransformation.

Published in:

Mutagenesis, 2005, v. 20, n. 2, p. 93, doi. 10.1093/mutage/gei012

By:

Maria Paula Duarte;
Bernardo Brito Palma;
Andrei A. Gilep;
Antnio Laires;
Jos Santos Oliveira;
Sergey A. Usanov;
Jos Rueff;
Michel Kranendonk

Publication type:

Article