Works by Gilardi, Gianfranco

Results: 54

Human Cytochrome P450 3A4 as a Biocatalyst: Effects of the Engineered Linker in Modulation of Coupling Efficiency in 3A4-BMR Chimeras.

Published in:

Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00121

By:

Degregorio, Danilo;
D'Avino, Serena;
Castrignanò, Silvia;
Di Nardo, Giovanna;
Sadeghi, Sheila J.;
Catucci, Gianluca;
Gilardi, Gianfranco

Publication type:

Article

Assessment of Five Pesticides as Endocrine-Disrupting Chemicals: Effects on Estrogen Receptors and Aromatase.

Published in:

International Journal of Environmental Research & Public Health, 2022, v. 19, n. 4, p. 1959, doi. 10.3390/ijerph19041959

By:

Gea, Marta;
Zhang, Chao;
Tota, Roberta;
Gilardi, Gianfranco;
Di Nardo, Giovanna;
Schilirò, Tiziana

Publication type:

Article

Molecular Basis for Endocrine Disruption by Pesticides Targeting Aromatase and Estrogen Receptor.

Published in:

International Journal of Environmental Research & Public Health, 2020, v. 17, n. 16, p. 5664, doi. 10.3390/ijerph17165664

By:

Zhang, Chao;
Schilirò, Tiziana;
Gea, Marta;
Bianchi, Silvia;
Spinello, Angelo;
Magistrato, Alessandra;
Gilardi, Gianfranco;
Di Nardo, Giovanna

Publication type:

Article

Editorial: Special Issue on "Flavin Monooxygenases".

Published in:

2021

By:

Gilardi, Gianfranco;
Sadeghi, Sheila J.

Publication type:

Editorial

Enzymatically Produced Trimethylamine N-Oxide: Conserving It or Eliminating It.

Published in:

Catalysts (2073-4344), 2019, v. 9, n. 12, p. 1028, doi. 10.3390/catal9121028

By:

Catucci, Gianluca;
Querio, Giulia;
Sadeghi, Sheila J.;
Gilardi, Gianfranco;
Levi, Renzo

Publication type:

Article

Basic and applied science at the time of COVID‐19.

Published in:

FEBS Letters, 2020, v. 594, n. 18, p. 2933, doi. 10.1002/1873-3468.13927

By:

Bolognesi, Martino;
Magnani, Mauro;
Cutruzzolà, Francesca;
Monti, Eugenio;
Capitanio, Nazzareno;
Condorelli, Daniele;
Della Ragione, Fulvio;
Federici, Luca;
Gilardi, Gianfranco;
Hrelia, Silvana;
Lucacchini, Antonio;
Santucci, Annalisa;
Ammendola, Rosario;
Bellotti, Vittorio;
Bettuzzi, Saverio;
Caruso, Donatella;
Maccarrone, Mauro;
Passi, Alberto;
Palmieri, Luigi;
Ruoppolo, Margherita

Publication type:

Article

Multi‐Enzymatic Cascade Reactions for the Synthesis of cis,cis‐Muconic Acid.

Published in:

Advanced Synthesis & Catalysis, 2022, v. 364, n. 1, p. 114, doi. 10.1002/adsc.202100849

By:

Vignali, Elisa;
Pollegioni, Loredano;
Di Nardo, Giovanna;
Valetti, Francesca;
Gazzola, Silvia;
Gilardi, Gianfranco;
Rosini, Elena

Publication type:

Article

Identification of a novel Baeyer- Villiger monooxygenase from Acinetobacter radioresistens: close relationship to the Mycobacterium tuberculosis prodrug activator EtaA.

Published in:

Microbial Biotechnology, 2012, v. 5, n. 6, p. 700, doi. 10.1111/j.1751-7915.2012.00356.x

By:

Minerdi, Daniela;
Zgrablic, Ivan;
Sadeghi, Sheila J.;
Gilardi, Gianfranco

Publication type:

Article

EXTRACTION OF BIOCHEMICALS FROM THE WINE INDUSTRY BY-PRODUCTS AND THEIR VALORIZATION.

Published in:

Environmental Engineering & Management Journal (EEMJ), 2016, v. 15, n. 9, p. 2049, doi. 10.30638/eemj.2016.221

By:

Zitella, Paola;
La Licata, Barbara;
Boulanger, Alexia;
Cuzzola, Vincenzo;
Morra, Simone;
Valetti, Francesca;
Gilardi, Gianfranco

Publication type:

Article

Albumin/Mitotane Interaction Affects Drug Activity in Adrenocortical Carcinoma Cells: Smoke and Mirrors on Mitotane Effect with Possible Implications for Patients' Management.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 23, p. 16701, doi. 10.3390/ijms242316701

By:

Schiavon, Aurora;
Saba, Laura;
Catucci, Gianluca;
Petiti, Jessica;
Puglisi, Soraya;
Borin, Chiara;
Reimondo, Giuseppe;
Gilardi, Gianfranco;
Giachino, Claudia;
Terzolo, Massimo;
Lo Iacono, Marco

Publication type:

Article

Posttranslational Modification of Human Cytochrome CYP4F11 by 4-Hydroxynonenal Impairs ω-Hydroxylation in Malaria Pigment Hemozoin-Fed Monocytes: The Role in Malaria Immunosuppression.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 12, p. 10232, doi. 10.3390/ijms241210232

By:

Skorokhod, Oleksii;
Triglione, Vincenzo;
Barrera, Valentina;
Di Nardo, Giovanna;
Valente, Elena;
Ulliers, Daniela;
Schwarzer, Evelin;
Gilardi, Gianfranco

Publication type:

Article

Molecular Lego of Human Cytochrome P450: The Key Role of Heme Domain Flexibility for the Activity of the Chimeric Proteins.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 7, p. 3618, doi. 10.3390/ijms23073618

By:

Catucci, Gianluca;
Ciaramella, Alberto;
Di Nardo, Giovanna;
Zhang, Chao;
Castrignanò, Silvia;
Gilardi, Gianfranco

Publication type:

Article

Biocatalytic C-C Bond Formation for One Carbon Resource Utilization.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1890, doi. 10.3390/ijms22041890

By:

Yang, Qiaoyu;
Guo, Xiaoxian;
Liu, Yuwan;
Jiang, Huifeng;
Gilardi, Gianfranco

Publication type:

Article

Molecular and Structural Evolution of Cytochrome P450 Aromatase.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 2, p. 631, doi. 10.3390/ijms22020631

By:

Di Nardo, Giovanna;
Zhang, Chao;
Marcelli, Anna Giulia;
Gilardi, Gianfranco

Publication type:

Article

Effect of Human Flavin-Containing Monooxygenase 3 Polymorphism on the Metabolism of Aurora Kinase Inhibitors.

Published in:

International Journal of Molecular Sciences, 2013, v. 14, n. 2, p. 2707, doi. 10.3390/ijms14022707

By:

Catucci, Gianluca;
Occhipinti, Andrea;
Maffei, Massimo;
Gilardi, Gianfranco;
Sadeghi, Sheila J.

Publication type:

Article

Optimization of the Bacterial Cytochrome P450 BM3 System for the Production of Human Drug Metabolites.

Published in:

International Journal of Molecular Sciences, 2012, v. 13, n. 12, p. 15901, doi. 10.3390/ijms131215901

By:

Di Nardo, Giovanna;
Gilardi, Gianfranco

Publication type:

Article

Biochemical features of dye‐decolorizing peroxidases: Current impact on lignin degradation.

Published in:

Biotechnology & Applied Biochemistry, 2020, v. 67, n. 5, p. 751, doi. 10.1002/bab.2015

By:

Catucci, Gianluca;
Valetti, Francesca;
Sadeghi, Sheila J.;
Gilardi, Gianfranco

Publication type:

Article

Chimeric cytochrome P450 3A4 used for in vitro prediction of food–drug interactions.

Published in:

Biotechnology & Applied Biochemistry, 2020, v. 67, n. 4, p. 541, doi. 10.1002/bab.1993

By:

Sadeghi, Sheila J.;
Di Nardo, Giovanna;
Gilardi, Gianfranco

Publication type:

Article

Editorial to the Special Issue: “Biochemistry of Protein–Protein and Protein–Lipid Interactions: Applications to Biotechnology”.

Published in:

Biotechnology & Applied Biochemistry, 2018, v. 65, n. 1, p. 7, doi. 10.1002/bab.1643

By:

Dainese, Enrico;
Gilardi, Gianfranco;
Maccarrone, Mauro

Publication type:

Article

Working at the membrane interface: Ligand‐induced changes in dynamic conformation and oligomeric structure in human aromatase.

Published in:

Biotechnology & Applied Biochemistry, 2018, v. 65, n. 1, p. 46, doi. 10.1002/bab.1613

By:

Di Nardo, Giovanna;
Cimicata, Giuseppe;
Baravalle, Roberta;
Dell'Angelo, Valentina;
Ciaramella, Alberto;
Catucci, Gianluca;
Ugliengo, Piero;
Gilardi, Gianfranco

Publication type:

Article

Isolation and characterization of a new [FeFe]-hydrogenase from Clostridium perfringens.

Published in:

Biotechnology & Applied Biochemistry, 2016, v. 63, n. 3, p. 305, doi. 10.1002/bab.1382

By:

Morra, Simone;
Mongili, Beatrice;
Maurelli, Sara;
Gilardi, Gianfranco;
Valetti, Francesca

Publication type:

Article

Graphene oxide-mediated electrochemistry of glucose oxidase on glassy carbon electrodes.

Published in:

Biotechnology & Applied Biochemistry, 2016, v. 63, n. 2, p. 157, doi. 10.1002/bab.1392

By:

Castrignanò, Silvia;
Valetti, Francesca;
Gilardi, Gianfranco;
Sadeghi, Sheila J.

Publication type:

Article

Human aromatase: Perspectives in biochemistry and biotechnology.

Published in:

Biotechnology & Applied Biochemistry, 2013, v. 60, n. 1, p. 92, doi. 10.1002/bab.1088

By:

Di Nardo, Giovanna;
Gilardi, Gianfranco

Publication type:

Article

Cytochrome P450 biotechnology.

Published in:

Biotechnology & Applied Biochemistry, 2013, v. 60, n. 1, p. 1, doi. 10.1002/bab.1098

By:

Gilardi, Gianfranco

Publication type:

Article

Chimeric P450 enzymes: Activity of artificial redox fusions driven by different reductases for biotechnological applications.

Published in:

Biotechnology & Applied Biochemistry, 2013, v. 60, n. 1, p. 102, doi. 10.1002/bab.1086

By:

Sadeghi, Sheila J.;
Gilardi, Gianfranco

Publication type:

Article

Toward reduction in animal sacrifice for drugs: Molecular modeling of Macaca fascicularis P450 2C20 for virtual screening of Homo sapiens P450 2C8 substrates.

Published in:

Biotechnology & Applied Biochemistry, 2012, v. 59, n. 6, p. 479, doi. 10.1002/bab.1051

By:

Rua, Francesco;
Di Nardo, Giovanna;
Sadeghi, Sheila J.;
Gilardi, Gianfranco

Publication type:

Article

Editorial.

Published in:

Biotechnology & Applied Biochemistry, 2012, v. 59, n. 4, p. 269, doi. 10.1002/bab.1028

By:

Gilardi, Gianfranco;
Zhong, Jian-Jiang

Publication type:

Article

The role of P450 enzymes in malaria and other vector‐borne infectious diseases.

Published in:

Biofactors, 2024, v. 50, n. 1, p. 16, doi. 10.1002/biof.1996

By:

Skorokhod, Oleksii;
Vostokova, Ekaterina;
Gilardi, Gianfranco

Publication type:

Article

Design of a H2O2‐generating P450SPα fusion protein for high yield fatty acid conversion.

Published in:

Protein Science: A Publication of the Protein Society, 2022, v. 31, n. 12, p. 1, doi. 10.1002/pro.4501

By:

Giuriato, Daniele;
Correddu, Danilo;
Catucci, Gianluca;
Di Nardo, Giovanna;
Bolchi, Cristiano;
Pallavicini, Marco;
Gilardi, Gianfranco

Publication type:

Article

Depicting the proton relay network in human aromatase: New insights into the role of the alcohol‐acid pair.

Published in:

Protein Science: A Publication of the Protein Society, 2022, v. 31, n. 9, p. 1, doi. 10.1002/pro.4389

By:

Zhang, Chao;
Gilardi, Gianfranco;
Di Nardo, Giovanna

Publication type:

Article

Atypical effect of temperature tuning on the insertion of the catalytic iron-sulfur center in a recombinant [FeFe]-hydrogenase.

Published in:

Protein Science: A Publication of the Protein Society, 2015, v. 24, n. 12, p. 2090, doi. 10.1002/pro.2805

By:

Morra, Simone;
Cordara, Alessandro;
Gilardi, Gianfranco;
Valetti, Francesca

Publication type:

Article

Electro-catalysis by immobilised human flavin-containing monooxygenase isoform 3 (hFMO3).

Published in:

Analytical & Bioanalytical Chemistry, 2010, v. 398, n. 3, p. 1403, doi. 10.1007/s00216-010-4014-z

By:

Castrignanò, Silvia;
Sadeghi, Sheila J.;
Gilardi, Gianfranco

Publication type:

Article

Turin special issue: Biochemistry for tomorrow’s medicine

Published in:

2011

By:

Papa, Sergio;
Gilardi, Gianfranco;
Just, Wilhelm

Publication type:

Editorial

Improvement of Biocatalysts for Industrial and Environmental Purposes by Saturation Mutagenesis.

Published in:

Biomolecules (2218-273X), 2013, v. 3, n. 4, p. 778, doi. 10.3390/biom3040778

By:

Valetti, Francesca;
Gilardi, Gianfranco

Publication type:

Article

CYP116B5: a new class VII catalytically self-sufficient cytochrome P450 from A cinetobacter radioresistens that enables growth on alkanes.

Published in:

Molecular Microbiology, 2015, v. 95, n. 3, p. 539, doi. 10.1111/mmi.12883

By:

Minerdi, Daniela;
Sadeghi, Sheila J.;
Di Nardo, Giovanna;
Rua, Francesco;
Castrignanò, Silvia;
Allegra, Paola;
Gilardi, Gianfranco

Publication type:

Article

CYP116B5‐SOX: An artificial peroxygenase for drug metabolites production and bioremediation.

Published in:

Biotechnology Journal, 2024, v. 19, n. 5, p. 1, doi. 10.1002/biot.202300664

By:

Giuriato, Daniele;
Catucci, Gianluca;
Correddu, Danilo;
Nardo, Giovanna Di;
Gilardi, Gianfranco

Publication type:

Article

Cascade reactions with two non‐physiological partners for NAD(P)H regeneration via renewable hydrogen.

Published in:

Biotechnology Journal, 2024, v. 19, n. 4, p. 1, doi. 10.1002/biot.202300567

By:

Gasteazoro, Francisco;
Catucci, Gianluca;
Barbieri, Lisa;
De Angelis, Melissa;
Dalla Costa, Alessandro;
Sadeghi, Sheila J.;
Gilardi, Gianfranco;
Valetti, Francesca

Publication type:

Article

Catalytically self‐sufficient CYP116B5: Domain switch for improved peroxygenase activity.

Published in:

Biotechnology Journal, 2023, v. 18, n. 5, p. 1, doi. 10.1002/biot.202200622

By:

Correddu, Danilo;
Catucci, Gianluca;
Giuriato, Daniele;
Di Nardo, Giovanna;
Ciaramella, Alberto;
Gilardi, Gianfranco

Publication type:

Article

Identification of Mutant Asp251Gly/Gln307His of Cytochrome P450 BM3 for the Generation of Metabolites of Diclofenac, Ibuprofen and Tolbutamide.

Published in:

Chemistry - A European Journal, 2012, v. 18, n. 12, p. 3582, doi. 10.1002/chem.201102470

By:

Tsotsou, Georgia E.;
Sideri, Anastasia;
Goyal, Abhineet;
Di Nardo, Giovanna;
Gilardi, Gianfranco

Publication type:

Article

The potential of native and engineered Clostridia for biomass biorefining.

Published in:

Frontiers in Bioengineering & Biotechnology, 2024, p. 1, doi. 10.3389/fbioe.2024.1423935

By:

Ponsetto, Paola;
Sasal, Emilia Malgorzata;
Mazzoli, Roberto;
Valetti, Francesca;
Gilardi, Gianfranco

Publication type:

Article

The Cranberry Extract Oximacro® Exerts in vitro Virucidal Activity Against Influenza Virus by Interfering With Hemagglutinin.

Published in:

Frontiers in Microbiology, 2018, p. N.PAG, doi. 10.3389/fmicb.2018.01826

By:

Luganini, Anna;
Terlizzi, Maria E.;
Gribaudo, Giorgio;
Catucci, Gianluca;
Gilardi, Gianfranco;
Maffei, Massimo E.

Publication type:

Article

Ultrasound–Driven Deposition of Au and Ag Nanoparticles on Citrus Pectin: Preparation and Characterisation of Antimicrobial Composites.

Published in:

ChemPlusChem, 2024, v. 89, n. 7, p. 1, doi. 10.1002/cplu.202300774

By:

Bucciol, Fabio;
Manzoli, Maela;
Zhang, Chao;
Di Nardo, Giovanna;
Gilardi, Gianfranco;
Calcio Gaudino, Emanuela;
Cravotto, Giancarlo

Publication type:

Article

A safety cap protects hydrogenase from oxygen attack.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20861-2

By:

Winkler, Martin;
Duan, Jifu;
Rutz, Andreas;
Felbek, Christina;
Scholtysek, Lisa;
Lampret, Oliver;
Jaenecke, Jan;
Apfel, Ulf-Peter;
Gilardi, Gianfranco;
Valetti, Francesca;
Fourmond, Vincent;
Hofmann, Eckhard;
Léger, Christophe;
Happe, Thomas

Publication type:

Article

Dynamics and Flexibility of Human Aromatase Probed by FTIR and Time Resolved Fluorescence Spectroscopy.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0082118

By:

Di Nardo, Giovanna;
Breitner, Maximilian;
Sadeghi, Sheila J.;
Castrignanò, Silvia;
Mei, Giampiero;
Di Venere, Almerinda;
Nicolai, Eleonora;
Allegra, Paola;
Gilardi, Gianfranco

Publication type:

Article

Site Saturation Mutagenesis Demonstrates a Central Role for Cysteine 298 as Proton Donor to the Catalytic Site in CaHydA [FeFe]-Hydrogenase.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0048400

By:

Morra, Simone;
Giraudo, Alberto;
Di Nardo, Giovanna;
King, Paul W.;
Gilardi, Gianfranco;
Valetti, Francesca;
Marr, Andrew C.

Publication type:

Article

Polymorphism on human aromatase affects protein dynamics and substrate binding: spectroscopic evidence.

Published in:

Biology Direct, 2021, v. 16, n. 1, p. 1, doi. 10.1186/s13062-021-00292-9

By:

Di Nardo, Giovanna;
Di Venere, Almerinda;
Zhang, Chao;
Nicolai, Eleonora;
Castrignanò, Silvia;
Di Paola, Luisa;
Gilardi, Gianfranco;
Mei, Giampiero

Publication type:

Article

Production of drug metabolites by human FMO3 in Escherichia coli.

Published in:

Microbial Cell Factories, 2020, v. 19, n. 1, p. 1, doi. 10.1186/s12934-020-01332-1

By:

Catucci, Gianluca;
Gilardi, Gianfranco;
Sadeghi, Sheila J.

Publication type:

Article

Understanding uncoupling in the multiredox centre P450 3A4-BMR model system.

Published in:

Journal of Biological Inorganic Chemistry (JBIC), 2011, v. 16, n. 1, p. 109, doi. 10.1007/s00775-010-0708-0

By:

Degregorio, Danilo;
Sadeghi, Sheila;
Nardo, Giovanna;
Gilardi, Gianfranco;
Solinas, Sandro

Publication type:

Article

Engineering heme binding sites in monomeric rop.

Published in:

Journal of Biological Inorganic Chemistry (JBIC), 2009, v. 14, n. 4, p. 497, doi. 10.1007/s00775-009-0465-0

By:

Di Nardo, Giovanna;
Di Venere, Almerinda;
Giampiero Mei;
Sadeghi, Sheila J.;
Wilson, Jon R.;
Gilardi, Gianfranco

Publication type:

Article

Wild-type CYP102A1 as a biocatalyst: turnover of drugs usually metabolised by human liver enzymes.

Published in:

Journal of Biological Inorganic Chemistry (JBIC), 2007, v. 12, n. 3, p. 313, doi. 10.1007/s00775-006-0188-4

By:

Di Nardo, Giovanna;
Fantuzzi, Andrea;
Sideri, Anastasia;
Panicco, Paola;
Sassone, Carlo;
Giunta, Carlo;
Gilardi, Gianfranco

Publication type:

Article