Works by Gigant, Benoît

Results: 16

Structural basis for the regulation of tubulin by vinblastine.

Published in:

Nature, 2005, v. 435, n. 7041, p. 519, doi. 10.1038/nature03566

By:

Gigant, Benoît;
Wang, Chunguang;
Ravelli, Raimond B. G.;
Roussi, Fanny;
Steinmetz, Michel O.;
Curmi, Patrick A.;
Sobel, André;
Knossow, Marcel

Publication type:

Article

Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain.

Published in:

Nature, 2004, v. 428, n. 6979, p. 198, doi. 10.1038/nature02393

By:

Ravelli, Raimond B.G.;
Gigant, Benoît;
Curmi, Patrick A.;
Jourdain, Isabelle;
Lachkar, Sylvie;
Sobel, André;
Knossow, Marcel

Publication type:

Article

Crystallization and preliminary X-ray diffraction studies of complexes between an influenza hemagglutinin and fab fragments of two different monoclonal antibodies.

Published in:

Proteins, 1995, v. 23, n. 1, p. 115, doi. 10.1002/prot.340230113

By:

Gigant, Benoît;
Fleury, Damien;
Bizebard, Thierry;
Skehel, John J.;
Knossow, Marcel

Publication type:

Article

Structural insight into the inhibition of tubulin by vinca domain peptide ligands.

Published in:

EMBO Reports, 2008, v. 9, n. 11, p. 1101, doi. 10.1038/embor.2008.171

By:

Cormier, Anthony;
Marchand, Matthieu;
Ravelli, Raimond B G;
Knossow, Marcel;
Gigant, Benoît

Publication type:

Article

Kinesin, 30 years later: Recent insights from structural studies.

Published in:

Protein Science: A Publication of the Protein Society, 2015, v. 24, n. 7, p. 1047, doi. 10.1002/pro.2697

By:

Wang, Weiyi;
Cao, Luyan;
Wang, Chunguang;
Gigant, Benoît;
Knossow, Marcel

Publication type:

Article

Centriolar cap proteins CP110 and CPAP control slow elongation of microtubule plus ends.

Published in:

Journal of Cell Biology, 2025, v. 224, n. 3, p. 1, doi. 10.1083/jcb.202406061

By:

Iyer, Saishree S.;
Fangrui Chen;
Ogunmolu, Funso E.;
Moradi, Shoeib;
Volkov, Vladimir A.;
van Grinsven, Emma J.;
van Hoorn, Chris;
Jingchao Wu;
Andrea, Nemo;
Hua, Shasha;
Jiang, Kai;
Vakonakis, Ioannis;
Potočnjak, Mia;
Herzog, Franz;
Gigant, Benoît;
Gudimchuk, Nikita;
Stecker, Kelly E.;
Dogterom, Marileen;
Steinmetz, Michel O.;
Akhmanova, Anna

Publication type:

Article

NMR Meets Tau: Insights into Its Function and Pathology.

Published in:

Biomolecules (2218-273X), 2016, v. 6, n. 2, p. 28, doi. 10.3390/biom6020028

By:

Lippens, Guy;
Landrieu, Isabelle;
Smet, Caroline;
Huvent, Isabelle;
Gandhi, Neha S.;
Gigant, Benoît;
Despres, Clément;
Haoling Qi;
Lopez, Juan

Publication type:

Article

Insight into microtubule disassembly by kinesin-13s from the structure of Kif2C bound to tubulin.

Published in:

Nature Communications, 2017, v. 8, n. 7, p. 1, doi. 10.1038/s41467-017-00091-9

By:

Weiyi Wang;
Cantos-Fernandes, Soraya;
Yuncong Lv;
Hureshitanmu Kuerban;
Ahmad, Shoeb;
Chunguang Wang;
Gigant, Benoît

Publication type:

Article

Mechanism of microtubule stabilization by taccalonolide AJ.

Published in:

Nature Communications, 2017, v. 8, n. 6, p. 15787, doi. 10.1038/ncomms15787

By:

Wang, Yuxi;
Yu, Yamei;
Li, Guo-Bo;
Li, Shu-Ang;
Wu, Chengyong;
Gigant, Benoît;
Qin, Wenming;
Chen, Hao;
Wu, Yangping;
Chen, Qiang;
Yang, Jinliang

Publication type:

Article

The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movement.

Published in:

Nature Communications, 2014, v. 5, n. 11, p. 5364, doi. 10.1038/ncomms6364

By:

Cao, Luyan;
Wang, Weiyi;
Jiang, Qiyang;
Wang, Chunguang;
Knossow, Marcel;
Gigant, Benoît

Publication type:

Article

Structural snapshots of the kinesin‐2 OSM‐3 along its nucleotide cycle: implications for the ATP hydrolysis mechanism.

Published in:

FEBS Open Bio, 2021, v. 11, n. 3, p. 564, doi. 10.1002/2211-5463.13101

By:

Varela, Paloma F.;
Chenon, Mélanie;
Velours, Christophe;
Verhey, Kristen J.;
Ménétrey, Julie;
Gigant, Benoît;
Wlodawer, Alex

Publication type:

Article

Structure of a kinesin-tubulin complex and implications for kinesin motility.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 8, p. 1001, doi. 10.1038/nsmb.2624

By:

Gigant, Benoît;
Wang, Weiyi;
Dreier, Birgit;
Jiang, Qiyang;
Pecqueur, Ludovic;
Plückthun, Andreas;
Wang, Chunguang;
Knossow, Marcel

Publication type:

Article

Microtubule‐targeting agents for cancer treatment: Seven binding sites and three strategies.

Published in:

Medcomm: Oncology, 2023, v. 2, n. 3, p. 1, doi. 10.1002/mog2.46

By:

Wang, Xingyu;
Gigant, Benoît;
Zheng, Xi;
Chen, Qiang

Publication type:

Article

The structural switch of nucleotide-free kinesin.

Published in:

Scientific Reports, 2017, p. 42558, doi. 10.1038/srep42558

By:

Cao, Luyan;
Cantos-Fernandes, Soraya;
Gigant, Benoît

Publication type:

Article

Destabilizing an interacting motif strengthens the association of a designed ankyrin repeat protein with tubulin.

Published in:

Scientific Reports, 2016, p. 28922, doi. 10.1038/srep28922

By:

Ahmad, Shoeb;
Pecqueur, Ludovic;
Dreier, Birgit;
Hamdane, Djemel;
Aumont-Nicaise, Magali;
Plückthun, Andreas;
Knossow, Marcel;
Gigant, Benoît

Publication type:

Article

Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.

Published in:

FEBS Journal, 2016, v. 283, n. 1, p. 102, doi. 10.1111/febs.13555

By:

Wang, Yuxi;
Zhang, Hang;
Gigant, Benoît;
Yu, Yamei;
Wu, Yangping;
Chen, Xiangzheng;
Lai, Qinhuai;
Yang, Zhaoya;
Chen, Qiang;
Yang, Jinliang

Publication type:

Article