Works by Giera, Martin

Results: 89
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    Totum-070, a Polyphenol-Rich Plant Extract, Prevents Hypercholesterolemia in High-Fat Diet-Fed Hamsters by Inhibiting Intestinal Cholesterol Absorption.

    Published in:
    Nutrients, 2023, v. 15, n. 24, p. 5056, doi. 10.3390/nu15245056
    By:
    • Langhi, Cédric;
    • Vallier, Marie;
    • Otero, Yolanda F.;
    • Maura, Maheva;
    • Le Joubioux, Florian;
    • Groult, Hugo;
    • Achour, Oussama;
    • Pebriana, Ratna Budhi;
    • Giera, Martin;
    • Guigas, Bruno;
    • Maugard, Thierry;
    • Chassaing, Benoit;
    • Peltier, Sébastien;
    • Bard, Jean-Marie;
    • Sirvent, Pascal
    Publication type:
    Article
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    Microbiota-derived short chain fatty acids modulate microglia and promote Ab plaque deposition.

    Published in:
    eLife, 2021, p. 1, doi. 10.7554/eLife.59826
    By:
    • Colombo, Alessio Vittorio;
    • Sadler, Rebecca Katie;
    • Llovera, Gemma;
    • Singh, Vikramjeet;
    • Roth, Stefan;
    • Heindl, Steffanie;
    • Monasor, Laura Sebastian;
    • Verhoeven, Aswin;
    • Peters, Finn;
    • Parhizkar, Samira;
    • Kamp, Frits;
    • Gomez de Aguero, Mercedes;
    • MacPherson, Andrew J.;
    • Winkler, Edith;
    • Herms, Jochen;
    • Benakis, Corinne;
    • Dichgans, Martin;
    • Steiner, Harald;
    • Giera, Martin;
    • Haass, Christian
    Publication type:
    Article
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    Bone marrow transplantation induces changes in the gut microbiota that chronically increase the cytokine response pattern of splenocytes.

    Published in:
    Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-10637-7
    By:
    • Katiraei, Saeed;
    • van Diepen, Janna A.;
    • Tavares, Luciana P.;
    • Hoving, Lisa R.;
    • Pronk, Amanda;
    • Verschueren, Ineke;
    • Rensen, Patrick C. N.;
    • Zwaginga, Jaap Jan;
    • Kostidis, Sarantos;
    • Giera, Martin;
    • Teixera, Mauro;
    • van Dijk, Ko Willems;
    • Netea, Mihai G.;
    • Berbée, Jimmy F. P.;
    • van Harmelen, Vanessa
    Publication type:
    Article
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    Altered high‐density lipoprotein composition is associated with risk for complications in type 2 diabetes mellitus in South Asian descendants: A cross‐sectional, case‐control study on lipoprotein subclass profiling.

    Published in:
    Diabetes, Obesity & Metabolism, 2023, v. 25, n. 8, p. 2374, doi. 10.1111/dom.15118
    By:
    • Yuan, Lushun;
    • Li‐Gao, Ruifang;
    • Verhoeven, Aswin;
    • van Eyk, Huub J.;
    • Bizino, Maurice B.;
    • Rensen, Patrick C. N.;
    • Giera, Martin;
    • Jazet, Ingrid M.;
    • Lamb, Hildo J.;
    • Rabelink, Ton J.;
    • van den Berg, Bernard M.
    Publication type:
    Article
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    Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24353-9
    By:
    • Traube, Franziska R.;
    • Özdemir, Dilara;
    • Sahin, Hanife;
    • Scheel, Constanze;
    • Glück, Andrea F.;
    • Geserich, Anna S.;
    • Oganesian, Sabine;
    • Kostidis, Sarantos;
    • Iwan, Katharina;
    • Rahimoff, René;
    • Giorgio, Grazia;
    • Müller, Markus;
    • Spada, Fabio;
    • Biel, Martin;
    • Cox, Jürgen;
    • Giera, Martin;
    • Michalakis, Stylianos;
    • Carell, Thomas
    Publication type:
    Article
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    Lowering the increased intracellular pH of human‐induced pluripotent stem cell‐derived endothelial cells induces formation of mature Weibel‐Palade bodies.

    Published in:
    Stem Cells Translational Medicine, 2020, v. 9, n. 7, p. 758, doi. 10.1002/sctm.19-0392
    By:
    • Tiemeier, Gesa L.;
    • Koning, Rozemarijn;
    • Wang, Gangqi;
    • Kostidis, Sarantos;
    • Rietjens, Rosalie G. J.;
    • Sol, Wendy M. P. J.;
    • Dumas, Sébastien J.;
    • Giera, Martin;
    • Berg, Cathelijne W.;
    • Eikenboom, Jeroen C. J.;
    • Berg, Bernard M.;
    • Carmeliet, Peter;
    • Rabelink, Ton J.
    Publication type:
    Article
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    Oleic acid enhances proliferation and calcium mobilization of CD3/CD28 activated CD4<sup>+</sup> T cells through incorporation into membrane lipids.

    Published in:
    European Journal of Immunology, 2024, v. 54, n. 9, p. 1, doi. 10.1002/eji.202350685
    By:
    • von Hegedus, Johannes Hendrick;
    • de Jong, Anja J.;
    • Hoekstra, Anna T.;
    • Spronsen, Eric;
    • Zhu, Wahwah;
    • Cabukusta, Birol;
    • Kwekkeboom, Joanneke C.;
    • Heijink, Marieke;
    • Bos, Erik;
    • Berkers, Celia R.;
    • Giera, Martin A.;
    • Toes, Rene E. M.;
    • Ioan‐Facsinay, Andreea
    Publication type:
    Article
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    Adipocyte-derived lipids modulate CD4<sup>+</sup> T-cell function.

    Published in:
    European Journal of Immunology, 2013, v. 43, n. 6, p. 1578, doi. 10.1002/eji.201243096
    By:
    • Ioan ‐ Facsinay, Andreea;
    • Kwekkeboom, Joanneke C.;
    • Westhoff, Sanne;
    • Giera, Martin;
    • Rombouts, Yoann;
    • Harmelen, Vanessa;
    • Huizinga, Tom W. J.;
    • Deelder, André;
    • Kloppenburg, Margreet;
    • Toes, René E. M.
    Publication type:
    Article
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    Fatty acid metabolism in aggressive B-cell lymphoma is inhibited by tetraspanin CD37.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33138-7
    By:
    • Peeters, Rens;
    • Cuenca-Escalona, Jorge;
    • Zaal, Esther A.;
    • Hoekstra, Anna T.;
    • Balvert, Anouk C. G.;
    • Vidal-Manrique, Marcos;
    • Blomberg, Niek;
    • van Deventer, Sjoerd J.;
    • Stienstra, Rinke;
    • Jellusova, Julia;
    • Giera, Martin;
    • Hannibal, Luciana;
    • Spiekerkoetter, Ute;
    • ter Beest, Martin;
    • Berkers, Celia R.;
    • van Spriel, Annemiek B.
    Publication type:
    Article
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    Schistosoma haematobium infection is associated with lower serum cholesterol levels and improved lipid profile in overweight/obese individuals.

    Published in:
    PLoS Neglected Tropical Diseases, 2020, v. 14, n. 7, p. 1, doi. 10.1371/journal.pntd.0008464
    By:
    • Zinsou, Jeannot F.;
    • Janse, Jacqueline J.;
    • Honpkehedji, Josiane Y.;
    • Dejon-Agobé, Jean Claude;
    • García-Tardón, Noemí;
    • Hoekstra, Pytsje T.;
    • Massinga-Loembe, Marguerite;
    • Corstjens, Paul L. A. M.;
    • van Dam, Govert J.;
    • Giera, Martin;
    • Kremsner, Peter G.;
    • Yazdanbakhsh, Maria;
    • Adegnika, Ayola A.;
    • Guigas, Bruno
    Publication type:
    Article
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    Phenomics‐Based Discovery of Novel Orthosteric Choline Kinase Inhibitors.

    Published in:
    Angewandte Chemie International Edition, 2025, v. 64, n. 7, p. 1, doi. 10.1002/anie.202420149
    By:
    • Bauer, Ludwig G.;
    • Ward, Jennifer A.;
    • Díaz‐Sáez, Laura;
    • Sundström, Yvonne;
    • Tolvanen, Tuomas;
    • Alarcón Barrera, Juan Carlos;
    • Kostidis, Sarantos;
    • Rogers, Catherine M.;
    • Panagakou, Ioanna;
    • Singh, Usha;
    • Rothweiler, Elisabeth M.;
    • Gonzalez Orta, Alejandro;
    • Kaniskan, H. Ümit;
    • Hu, Jianping;
    • Jin, Jian;
    • Sievers, Sonja;
    • Waldmann, Herbert;
    • Giera, Martin;
    • Sundström, Michael;
    • Berg, Louise
    Publication type:
    Article
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    Multiomics of iPSC‐derived ApoE3‐ and ApoE4 astrocytes and microglia uncovers cell type specific dysregulation of immunometabolism.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080797
    By:
    • van der Kant, Rik;
    • Blomberg, Niek;
    • Erlebach, Lena;
    • Feringa, Femke M;
    • Heijneman, Jorin;
    • Koppes, Sascha;
    • Kruijff, Iris Daphne;
    • McQuade, Amanda;
    • Miramontes, Ricardo;
    • Olivier‐Jimenez, Damien;
    • Robert, Aiko;
    • Thompson, Leslie M.;
    • Ori, Alessandro;
    • Kronenberg‐Versteeg, Deborah;
    • Mohammed, Yassene;
    • Kampmann, Martin;
    • Giera, Martin
    Publication type:
    Article
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    Multi‐omic profiling of isogenic ApoE3/3 and ApoE4/4 iPSC‐derived astrocytes uncovers altered lipid metabolism and mitochondrial function of ApoE4 astrocytes.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078264
    By:
    • Koppes, Sascha;
    • Feringa, Femke M;
    • Robert, Aiko;
    • Kruijff, Iris Daphne;
    • Olivier‐Jimenez, Damien;
    • Erlebach, Lena;
    • Thompson, Leslie M.;
    • Kronenberg‐Versteeg, Deborah;
    • Ori, Alessandro;
    • Mohammed, Yassene;
    • Giera, Martin;
    • van der Kant, Rik
    Publication type:
    Article
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    Phänomik‐basierte Entdeckung neuer orthosterischer Cholinkinase Inhibitoren.

    Published in:
    Angewandte Chemie, 2025, v. 137, n. 7, p. 1, doi. 10.1002/ange.202420149
    By:
    • Bauer, Ludwig G.;
    • Ward, Jennifer A.;
    • Díaz‐Sáez, Laura;
    • Sundström, Yvonne;
    • Tolvanen, Tuomas;
    • Alarcón Barrera, Juan Carlos;
    • Kostidis, Sarantos;
    • Rogers, Catherine M.;
    • Panagakou, Ioanna;
    • Singh, Usha;
    • Rothweiler, Elisabeth M.;
    • Gonzalez Orta, Alejandro;
    • Kaniskan, H. Ümit;
    • Hu, Jianping;
    • Jin, Jian;
    • Sievers, Sonja;
    • Waldmann, Herbert;
    • Giera, Martin;
    • Sundström, Michael;
    • Berg, Louise
    Publication type:
    Article
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    Disturbed brain ether lipid metabolism and histology in Sjögren‐Larsson syndrome.

    Published in:
    Journal of Inherited Metabolic Disease, 2020, v. 43, n. 6, p. 1265, doi. 10.1002/jimd.12275
    By:
    • Staps, Pippa;
    • Rizzo, William B.;
    • Vaz, Frédéric M.;
    • Bugiani, Marianna;
    • Giera, Martin;
    • Heijs, Bram;
    • Kampen, Antoine H. C.;
    • Pras‐Raves, Mia L.;
    • Breur, Marjolein;
    • Groen, Annemieke;
    • Ferdinandusse, Sacha;
    • Graaf, Marinette;
    • Van Goethem, Gert;
    • Lammens, Martin;
    • Wevers, Ron A.;
    • Willemsen, Michèl A. A. P.
    Publication type:
    Article
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    Distinct intestinal microbial signatures linked to accelerated systemic and intestinal biological aging.

    Published in:
    Microbiome, 2024, v. 21, p. 1, doi. 10.1186/s40168-024-01758-4
    By:
    • Singh, Shalini;
    • Giron, Leila B.;
    • Shaikh, Maliha W.;
    • Shankaran, Shivanjali;
    • Engen, Phillip A.;
    • Bogin, Zlata R.;
    • Bambi, Simona A.;
    • Goldman, Aaron R.;
    • Azevedo, Joao L. L. C.;
    • Orgaz, Lorena;
    • de Pedro, Nuria;
    • González, Patricia;
    • Giera, Martin;
    • Verhoeven, Aswin;
    • Sánchez-López, Elena;
    • Pandrea, Ivona;
    • Kannan, Toshitha;
    • Tanes, Ceylan E.;
    • Bittinger, Kyle;
    • Landay, Alan L.
    Publication type:
    Article
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