Works by Gicquel, Thomas

Results: 41

Production of chlorzoxazone glucuronides via cytochrome P4502E1 dependent and independent pathways in human hepatocytes.

Published in:

Archives of Toxicology, 2018, v. 92, n. 10, p. 3077, doi. 10.1007/s00204-018-2300-2

By:

Quesnot, Nicolas;
Bucher, Simon;
Gade, Christina;
Vlach, Manuel;
Vene, Elise;
Valença, Samuel;
Gicquel, Thomas;
Holst, Helle;
Robin, Marie-Anne;
Loyer, Pascal

Publication type:

Article

Amatoxins (α- and β-Amanitin) and Phallotoxin (Phalloidin) Analyses in Urines Using High-Resolution Accurate Mass LC–MS Technology.

Published in:

Journal of Analytical Toxicology, 2014, v. 38, n. 6, p. 335, doi. 10.1093/jat/bku035

By:

Gicquel, Thomas;
Lepage, Sylvie;
Fradin, Manon;
Tribut, Olivier;
Duretz, Bénédicte;
Morel, Isabelle

Publication type:

Article

Quantitative Analysis of Acetaminophen and its Primary Metabolites in Small Plasma Volumes by Liquid Chromatography-Tandem Mass Spectrometry.

Published in:

Journal of Analytical Toxicology, 2013, v. 37, n. 2, p. 110, doi. 10.1093/jat/bks139

By:

Gicquel, Thomas;
Aubert, Jacinthe;
Lepage, Sylvie;
Fromenty, Bernard;
Morel, Isabelle

Publication type:

Article

New insights into quetiapine metabolism using molecular networking.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-77106-x

By:

Le Daré, Brendan;
Ferron, Pierre-Jean;
Allard, Pierre-Marie;
Clément, Bruno;
Morel, Isabelle;
Gicquel, Thomas

Publication type:

Article

Alteration of immunophenotype of human macrophages and monocytes after exposure to cigarette smoke.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-68753-1

By:

da Silva, Camila Oliveira;
Gicquel, Thomas;
Daniel, Yoann;
Bártholo, Thiago;
Vène, Elise;
Loyer, Pascal;
Pôrto, Luís Cristóvão;
Lagente, Vincent;
Victoni, Tatiana

Publication type:

Article

The release of pro-inflammatory cytokines is mediated via mitogen-activated protein kinases rather than by the inflammasome signalling pathway in keratinocytes.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2017, v. 44, n. 7, p. 827, doi. 10.1111/1440-1681.12765

By:

Ondet, Thomas;
Muscatelli‐Groux, Béatrice;
Coulouarn, Cédric;
Robert, Sacha;
Gicquel, Thomas;
Bodin, Aude;
Lagente, Vincent;
Grimaud, Jean‐Alexis

Publication type:

Article

Cas clinique : à propos d'une intoxication à la strychnine par la teinture mère Nux vomica.

Published in:

2012

By:

Gicquel, Thomas;
Lepage, Sylvie;
Baert, Alain;
Morel, Isabelle

Publication type:

Case Study

Metabolite elucidation of 2‐fluoro‐deschloroketamine (2F‐DCK) using molecular networking across three complementary in vitro and in vivo models.

Published in:

Drug Testing & Analysis, 2022, v. 14, n. 1, p. 144, doi. 10.1002/dta.3162

By:

Gicquel, Thomas;
Pelletier, Romain;
Richeval, Camille;
Gish, Alexandr;
Hakim, Florian;
Ferron, Pierre‐Jean;
Mesli, Vadim;
Allorge, Delphine;
Morel, Isabelle;
Gaulier, Jean‐michel

Publication type:

Article

Application of a molecular networking approach for clinical and forensic toxicology exemplified in three cases involving 3‐MeO‐PCP, doxylamine, and chlormequat.

Published in:

Drug Testing & Analysis, 2019, v. 11, n. 5, p. 669, doi. 10.1002/dta.2550

By:

Allard, Sophie;
Allard, Pierre‐Marie;
Morel, Isabelle;
Gicquel, Thomas

Publication type:

Article

Chronic and low exposure to a pharmaceutical cocktail induces mitochondrial dysfunction in liver and hyperglycemia: Differential responses between lean and obese mice.

Published in:

Environmental Toxicology, 2017, v. 32, n. 4, p. 1375, doi. 10.1002/tox.22331

By:

Buron, Nelly;
Porceddu, Mathieu;
Roussel, Célestin;
Begriche, Karima;
Trak‐Smayra, Viviane;
Gicquel, Thomas;
Fromenty, Bernard;
Borgne‐Sanchez, Annie

Publication type:

Article

Involvement of purinergic receptors and NOD-like receptor-family protein 3-inflammasome pathway in the adenosine triphosphate-induced cytokine release from macrophages.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2014, v. 41, n. 4, p. 279, doi. 10.1111/1440-1681.12214

By:

Gicquel, Thomas;
Victoni, Tatiana;
Fautrel, Alain;
Robert, Sacha;
Gleonnec, Florence;
Guezingar, Marie;
Couillin, Isabelle;
Catros, Véronique;
Boichot, Elisabeth;
Lagente, Vincent

Publication type:

Article

Toxic Effects of Amanitins: Repurposing Toxicities toward New Therapeutics.

Published in:

Toxins, 2021, v. 13, n. 6, p. 417, doi. 10.3390/toxins13060417

By:

Le Daré, Brendan;
Ferron, Pierre-Jean;
Gicquel, Thomas

Publication type:

Article

Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1β or TNF-α Release from Human Hepatic Stellate Cells.

Published in:

PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0153118

By:

Robert, Sacha;
Gicquel, Thomas;
Bodin, Aude;
Lagente, Vincent;
Boichot, Elisabeth

Publication type:

Article

Acetaminophen (APAP, Paracetamol) Interferes With the First Trimester Human Fetal Ovary Development in an Ex Vivo Model.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 6, p. 1647, doi. 10.1210/clinem/dgac080

By:

Lecante, Laetitia L.;
Leverrier-Penna, Sabrina;
Gicquel, Thomas;
Giton, Frank;
Costet, Nathalie;
Desdoits-Lethimonier, Christèle;
Lesné, Laurianne;
Fromenty, Bernard;
Lavoué, Vincent;
Rolland, Antoine D.;
Mazaud-Guittot, Séverine

Publication type:

Article

Therapeutic Applications of Ethanol: A Review.

Published in:

2019

By:

Le Daré, Brendan;
Gicquel, Thomas

Publication type:

journal article

In silico and in vitro metabolism studies of the new synthetic opiate AP-237 (bucinnazine) using bioinformatics tools.

Published in:

Archives of Toxicology, 2024, v. 98, n. 1, p. 165, doi. 10.1007/s00204-023-03617-x

By:

Pelletier, Romain;
Bourdais, Alexis;
Fabresse, Nicolas;
Ferron, Pierre-Jean;
Morel, Isabelle;
Gicquel, Thomas;
Le Daré, Brendan

Publication type:

Article

Identification, synthesis and quantification of eutylone consumption markers in a chemsex context.

Published in:

2024

By:

Pelletier, Romain;
Le Daré, Brendan;
Le Bouëdec, Diane;
Bourdais, Alexis;
Ferron, Pierre-Jean;
Morel, Isabelle;
Porée, François-Hugues;
Gicquel, Thomas

Publication type:

Case Study

Use of innovative, cross-disciplinary in vitro, in silico and in vivo approaches to characterize the metabolism of chloro-alpha-pyrrolidinovalerophenone (4-Cl-PVP).

Published in:

Archives of Toxicology, 2023, v. 97, n. 3, p. 671, doi. 10.1007/s00204-022-03427-7

By:

Pelletier, Romain;
Le Daré, Brendan;
Ferron, Pierre-Jean;
Le Bouëdec, Diane;
Kernalléguen, Angéline;
Morel, Isabelle;
Gicquel, Thomas

Publication type:

Article

New psychoactive substance cocktail in an intensive care intoxication case elucidated by molecular networking.

Published in:

Clinical Toxicology (15563650), 2022, v. 60, n. 1, p. 122, doi. 10.1080/15563650.2021.1931693

By:

Pelletier, Romain;
Le Daré, Brendan;
Grandin, Loic;
Couette, Aurélien;
Ferron, Pierre-Jean;
Morel, Isabelle;
Gicquel, Thomas

Publication type:

Article

Magic truffle intoxication: A case report.

Published in:

Emergency Care Journal, 2022, v. 18, n. 2, p. 1, doi. 10.4081/ecj.2022.10347

By:

Le Daré, Brendan;
Pelletier, Romain;
Couette, Aurèlien;
Morel, Isabelle;
Gicquel, Thomas

Publication type:

Article

A predictive score of high tibial osteotomy survivorship to help in surgical decision-making: the SKOOP score.

Published in:

Archives of Orthopaedic & Trauma Surgery, 2023, v. 143, n. 8, p. 4843, doi. 10.1007/s00402-022-04694-w

By:

Batailler, Cécile;
Gicquel, Thomas;
Bouguennec, Nicolas;
Steltzlen, Camille;
Tardy, Nicolas;
Cartier, Jean-Loup;
Mertl, Patrice;
Pailhé, Régis;
Rochcongar, Goulven;
Fayard, Jean Marie

Publication type:

Article

The Conditions and Quality of Postmortem Hair Sampling May Have a Subsequent Impact on the Interpretation of Toxicological Results in Hair.

Published in:

Journal of Analytical Toxicology, 2023, v. 47, n. 1, p. e17, doi. 10.1093/jat/bkac076

By:

Gicquel, Thomas;
Wiart, Jean-François;
Gish, Alexandr;
Hakim, Florian;
Allorge, Delphine;
Gaulier, Jean-Michel

Publication type:

Article

Determination of Orellanine in Human Biological Matrices Using Liquid Chromatography with High-Resolution Mass Spectrometry Detection: A Validated Method Applied to Suspected Poisoning Cases.

Published in:

Journal of Analytical Toxicology, 2023, v. 47, n. 1, p. 26, doi. 10.1093/jat/bkac018

By:

Flament, Estelle;
Guitton, Jérôme;
Gicquel, Thomas;
Paret, Nathalie;
Jarrier, Nathalie;
Creusat, Gaelle;
Tournoud, Christine;
Labadie, Magali;
Gaulier, Jean-Michel;
Gaillard, Yvan

Publication type:

Article

Involvement of matrix metalloproteinases (MMPs) and inflammasome pathway in molecular mechanisms of fibrosis.

Published in:

Bioscience Reports, 2016, v. 36, n. 4, p. 1, doi. 10.1042/BSR20160107

By:

Robert, Sacha;
Gicquel, Thomas;
Victoni, Tatiana;
Valença, Samuel;
Barreto, Emiliano;
Bailly-Maître, Béatrice;
Boichot, Elisabeth;
Lagente, Vincent

Publication type:

Article

Il était une fois l'hépatotoxicité...

Published in:

Médecine Sciences, 2021, v. 37, n. 3, p. 235, doi. 10.1051/medsci/2021009

By:

Le Daré, Brendan;
Ferron, Pierre-Jean;
Gicquel, Thomas

Publication type:

Article

Arylcyclohexylamine Derivatives: Pharmacokinetic, Pharmacodynamic, Clinical and Forensic Aspects.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 15574, doi. 10.3390/ijms232415574

By:

Pelletier, Romain;
Le Daré, Brendan;
Le Bouëdec, Diane;
Kernalléguen, Angéline;
Ferron, Pierre-Jean;
Morel, Isabelle;
Gicquel, Thomas

Publication type:

Article

Molecular Networking for Drug Toxicities Studies: The Case of Hydroxychloroquine in COVID-19 Patients.

Published in:

2022

By:

Ferron, Pierre-Jean;
Le Daré, Brendan;
Bronsard, Julie;
Steichen, Clara;
Babina, Elodie;
Pelletier, Romain;
Hauet, Thierry;
Morel, Isabelle;
Tarte, Karin;
Reizine, Florian;
Clément, Bruno;
Fromenty, Bernard;
Gicquel, Thomas

Publication type:

Abstract

The Purinergic P2X7 Receptor-NLRP3 Inflammasome Pathway: A New Target in Alcoholic Liver Disease?

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 2139, doi. 10.3390/ijms22042139

By:

Le Daré, Brendan;
Ferron, Pierre-Jean;
Gicquel, Thomas;
Teschke, Rolf

Publication type:

Article

Severe 25E-NBOH intoxication associated with MDPHP intake: a case report, metabolism study, and literature review.

Published in:

International Journal of Legal Medicine, 2024, v. 138, n. 3, p. 815, doi. 10.1007/s00414-023-03151-6

By:

Pelletier, Romain;
Gicquel, Thomas;
Carvelli, Julien;
Balaz, Pierre;
Pelissier-Alicot, Anne-Laure;
Morel, Isabelle;
Bottinelli, Charline;
Solas, Caroline;
Le Daré, Brendan;
Fabresse, Nicolas

Publication type:

Article

Carbofuran self-poisoning: forensic and analytic investigations in twins and literature review.

Published in:

International Journal of Legal Medicine, 2022, v. 136, n. 6, p. 1585, doi. 10.1007/s00414-022-02885-z

By:

Kernalléguen, Angéline;
Le Daré, Brendan;
Pelletier, Romain;
Ferron, Pierre-Jean;
Maamar, Adel;
Bouvet, Renaud;
Baert, Alain;
Morel, Isabelle;
Gicquel, Thomas

Publication type:

Article

Comments on "Evaluation and review of ways to differentiate sources of ethanol in post-mortem blood".

Published in:

2021

By:

Hakim, Florian;
Gicquel, Thomas;
Allorge, Delphine;
Gaulier, Jean-michel

Publication type:

Letter

Correction to: A case of fatal acebutolol poisoning: an illustration of the potential of molecular networking.

Published in:

2020

By:

Le Daré, Brendan;
Allard, Sophie;
Bouvet, Renaud;
Baert, Alain;
Allard, Pierre-Marie;
Morel, Isabelle;
Gicquel, Thomas

Publication type:

Correction Notice

A case of fatal acebutolol poisoning: an illustration of the potential of molecular networking.

Published in:

International Journal of Legal Medicine, 2020, v. 134, n. 1, p. 251, doi. 10.1007/s00414-019-02062-9

By:

Le Daré, Brendan;
Allard, Sophie;
Bouvet, Renaud;
Baert, Alain;
Allard, Pierre-Marie;
Morel, Isabelle;
Gicquel, Thomas

Publication type:

Article

Effects of the nerve growth factor and its carrier protein on the inflammatory response from human monocytes.

Published in:

Fundamental & Clinical Pharmacology, 2024, v. 38, n. 5, p. 940, doi. 10.1111/fcp.13006

By:

Verres, Yann;
Bodin, Aude;
Chevret, Sarah;
Victoni, Tatiana;
Gicquel, Thomas;
Barreto, Emiliano;
Freund‐Michel, Véronique;
Lagente, Vincent

Publication type:

Article

Ethanol upregulates the P2X7 purinergic receptor in human macrophages.

Published in:

Fundamental & Clinical Pharmacology, 2019, v. 33, n. 1, p. 63, doi. 10.1111/fcp.12433

By:

Le Daré, Brendan;
Victoni, Tatiana;
Bodin, Aude;
Vlach, Manuel;
Vene, Elise;
Loyer, Pascal;
Lagente, Vincent;
Gicquel, Thomas

Publication type:

Article

Purinergic receptors: new targets for the treatment of gout and fibrosis.

Published in:

Fundamental & Clinical Pharmacology, 2017, v. 31, n. 2, p. 136, doi. 10.1111/fcp.12256

By:

Gicquel, Thomas;
Le Daré, Brendan;
Boichot, Elisabeth;
Lagente, Vincent

Publication type:

Article

A Transversal Approach Combining In Silico, In Vitro and In Vivo Models to Describe the Metabolism of the Receptor Interacting Protein 1 Kinase Inhibitor Sibiriline.

Published in:

Pharmaceutics, 2022, v. 14, n. 12, p. 2665, doi. 10.3390/pharmaceutics14122665

By:

Pelletier, Romain;
Gicquel, Thomas;
Simoes Eugenio, Mélanie;
Ferron, Pierre-Jean;
Morel, Isabelle;
Delehouzé, Claire;
Dimanche-Boitrel, Marie-Thérèse;
Rousselot, Morgane;
Le Daré, Brendan

Publication type:

Article

Is tibial cut navigation alone sufficient in medial unicompartmental knee arthroplasty? Continuous series of fifty nine procedures.

Published in:

2016

By:

Gicquel, Thomas;
Lambotte, Jean;
Polard, Jean;
Ropars, Mickael;
Huten, Denis;
Lambotte, Jean Christophe;
Polard, Jean Louis

Publication type:

journal article

Mise en évidence d'intoxications par ingestion de champignons supérieurs : expérience au CHU de Rennes.

Published in:

Annales de Biologie Clinique, 2022, v. 80, n. 2, p. 141, doi. 10.1684/abc.2022.1710

By:

Le Daré, Brendan;
Couette, Aurélien;
Pelletier, Romain;
Morel, Isabelle;
Gicquel, Thomas

Publication type:

Article

Ethanol and its metabolites: update on toxicity, benefits, and focus on immunomodulatory effects.

Published in:

Drug Metabolism Reviews, 2019, v. 51, n. 4, p. 545, doi. 10.1080/03602532.2019.1679169

By:

Le Daré, Brendan;
Lagente, Vincent;
Gicquel, Thomas

Publication type:

Article

IL-1β production is dependent on the activation of purinergic receptors and NLRP3 pathway in human macrophages.

Published in:

FASEB Journal, 2015, v. 29, n. 10, p. 4162, doi. 10.1096/fj.14-267393

By:

Gicquel, Thomas;
Robert, Sacha;
Loyer, Pascal;
Victoni, Tatiana;
Bodin, Aude;
Ribault, Catherine;
Gleonnec, Florence;
Couillin, Isabelle;
Boichot, Elisabeth;
Lagente, Vincent

Publication type:

Article