Works matching AU Giannoukakis, Nick

Results: 37

Cellular environment and freedom of gene expression.

Published in:

Nature Immunology, 2002, v. 3, n. 4, p. 335, doi. 10.1038/ni0402-335a

By:

Pietropaolo, Massimo;
Giannoukakis, Nick;
Trucco, Massimo

Publication type:

Article

Toward a cure for type 1 diabetes mellitus: diabetes-suppressive dendritic cells and beyond.

Published in:

Pediatric Diabetes, 2008, v. 9, n. 3pt2, p. 4, doi. 10.1111/j.1399-5448.2008.00401.x

By:

Giannoukakis, Nick;
Phillips, Brett;
Trucco, Massimo

Publication type:

Article

Islet/pancreas transplantation: challenges for pediatrics.

Published in:

Pediatric Diabetes, 2002, v. 3, n. 4, p. 210, doi. 10.1034/j.1399-5448.2002.30408.x

By:

Bottino, Rita;
Balamurugan, A.N.;
Giannoukakis, Nick;
Trucco, Massimo

Publication type:

Article

Tolerogenic dendritic cells in type 1 diabetes: no longer a concept.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1212641

By:

Giannoukakis, Nick

Publication type:

Article

Improvement in insulin sensitivity and prevention of high fat diet-induced liver pathology using a CXCR2 antagonist.

Published in:

Cardiovascular Diabetology, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12933-022-01564-y

By:

Phillips, Brett E.;
Lantier, Louise;
Engman, Carl;
Garciafigueroa, Yesica;
Singhi, Aatur;
Trucco, Massimo;
Mantzoros, Christos;
Wasserman, David;
Giannoukakis, Nick

Publication type:

Article

Improvement in insulin sensitivity and prevention of high fat diet-induced liver pathology using a CXCR2 antagonist.

Published in:

Cardiovascular Diabetology, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12933-022-01564-y

By:

Phillips, Brett E.;
Lantier, Louise;
Engman, Carl;
Garciafigueroa, Yesica;
Singhi, Aatur;
Trucco, Massimo;
Mantzoros, Christos;
Wasserman, David;
Giannoukakis, Nick

Publication type:

Article

Editorial: Diabetes and non-alcoholic fatty liver disease: points of physiological and mechanistic intersection and current co-therapeutic approaches.

Published in:

Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1253604

By:

Giannoukakis, Nick;
McCommis, Kyle S.

Publication type:

Article

Uncoupling hepatic insulin resistance - hepatic inflammation to improve insulin sensitivity and to prevent impaired metabolism-associated fatty liver disease in type 2 diabetes.

Published in:

Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1193373

By:

Niranjan, Sitara;
Phillips, Brett E.;
Giannoukakis, Nick

Publication type:

Article

Tolerogenic Dendritic Cells and T-Regulatory Cells at the Clinical Trials Crossroad for the Treatment of Autoimmune Disease; Emphasis on Type 1 Diabetes Therapy.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00148

By:

Phillips, Brett Eugene;
Garciafigueroa, Yesica;
Engman, Carl;
Trucco, Massimo;
Giannoukakis, Nick

Publication type:

Article

Co-Stimulation-Impaired Bone Marrow-Derived Dendritic Cells Prevent Dextran Sodium Sulfate-Induced Colitis in Mice.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00894

By:

Engman, Carl;
Garciafigueroa, Yesica;
Phillips, Brett Eugene;
Trucco, Massimo;
Giannoukakis, Nick

Publication type:

Article

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2017.01844

By:

Fuchs, Anke;
Gliwiński, Mateusz;
Grageda, Nathali;
Spiering, Rachel;
Abbas, Abul K.;
Appel, Silke;
Bacchetta, Rosa;
Battaglia, Manuela;
Berglund, David;
Blazar, Bruce;
Bluestone, Jeffrey A.;
Bornhäuser, Martin;
ten Brinke, Anja;
Brusko, Todd M.;
Cools, Nathalie;
Cuturi, Maria Cristina;
Geissler, Edward;
Giannoukakis, Nick;
Gołab, Karolina;
Hafler, David A.

Publication type:

Article

Phase I (Safety) Study of Autologous Tolerogenic Dendritic Cells in Type 1 Diabetic Patients.

Published in:

Diabetes Care, 2011, v. 34, n. 9, p. 2026, doi. 10.2337/dc11-0472

By:

GIANNOUKAKIS, NICK;
PHILLIPS, BRETT;
FINEGOLD, DAVID;
HARNAHA, JO;
TRUCCO, MASSIMO

Publication type:

Article

Current State of Type 1 Diabetes Immunotherapy: Incremental Advances, Huge Leaps, or More of the Same?

Published in:

Clinical & Developmental Immunology, 2011, p. 1, doi. 10.1155/2011/432016

By:

Phillips, Brett;
Trucco, Massimo;
Giannoukakis, Nick

Publication type:

Article

Neutrophils and their role in the aetiopathogenesis of type 1 and type 2 diabetes.

Published in:

Diabetes/Metabolism Research & Reviews, 2022, v. 38, n. 1, p. 1, doi. 10.1002/dmrr.3483

By:

Giovenzana, Anna;
Carnovale, Debora;
Phillips, Brett;
Petrelli, Alessandra;
Giannoukakis, Nick

Publication type:

Article

Cellular therapies based on stem cells and their insulin-producing surrogates: a 2015 reality check.

Published in:

Pediatric Diabetes, 2015, v. 16, n. 3, p. 151, doi. 10.1111/pedi.12259

By:

Giannoukakis, Nick;
Trucco, Massimo

Publication type:

Article

566. Delaying the Onset of Diabetes in the NOD Mouse Using Exosomes Derived from Dendritic Cells Transfected with Adenoviral Vectors.

Published in:

Molecular Therapy, 2006, v. 13, p. S218, doi. 10.1016/j.ymthe.2006.08.639

By:

Ruffner, Melanie A.;
Seon Hee Kim;
Bianco, Nicole R.;
Shufesky, William J.;
Giannoukakis, Nick;
Morelli, Adrian E.;
Robbins, Paul D.

Publication type:

Article

Neutrophil-Associated Inflammatory Changes in the Pre-Diabetic Pancreas of Early-Age NOD Mice.

Published in:

Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2021.565981

By:

Garciafigueroa, Yesica;
Phillips, Brett E.;
Engman, Carl;
Trucco, Massimo;
Giannoukakis, Nick

Publication type:

Article

Autoimmune Inflammation and Insulin Resistance: Hallmarks So Far and Yet So Close to Explain Diabetes Endotypes.

Published in:

2021

By:

Petrelli, Alessandra;
Giovenzana, Anna;
Insalaco, Vittoria;
Phillips, Brett E.;
Pietropaolo, Massimo;
Giannoukakis, Nick

Publication type:

journal article

Arrest in the Progression of Type 1 Diabetes at the Mid-Stage of Insulitic Autoimmunity Using an Autoantigen-Decorated All- trans Retinoic Acid and Transforming Growth Factor Beta-1 Single Microparticle Formulation.

Published in:

Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.586220

By:

Phillips, Brett E.;
Garciafigueroa, Yesica;
Engman, Carl;
Liu, Wen;
Wang, Yiwei;
Lakomy, Robert J.;
Meng, Wilson S.;
Trucco, Massimo;
Giannoukakis, Nick

Publication type:

Article

It's Time to Bring Dendritic Cell Therapy to Type 1 Diabetes.

Published in:

Diabetes, 2014, v. 63, n. 1, p. 20, doi. 10.2337/db13-0886

By:

Creusot, Rémi J.;
Giannoukakis, Nick;
Trucco, Massimo;
Clare-Salzler, Michael J.;
Fathman, C. Garrison

Publication type:

Article

FoxO6 Integrates Insulin Signaling With Gluconeogenesis in the Liver.

Published in:

Diabetes, 2011, v. 60, n. 11, p. 2763, doi. 10.2337/db11-0548

By:

Kim, Dae Hyun;
Perdomo, German;
Zhang, Ting;
Slusher, Sandra;
Lee, Sojin;
Phillips, Brett E.;
Fan, Yong;
Giannoukakis, Nick;
Gramignoli, Roberto;
Strom, Stephen;
Ringquist, Steven;
Dong, H. Henry

Publication type:

Article

Fox01 Links Insulin Resistance to Proinflammatory Cytokine IL-1β Production in Macrophages.

Published in:

Diabetes, 2009, v. 58, n. 11, p. 2624, doi. 10.2337/db09-0232

By:

Su, Dongming;
Coudriet, Gina M.;
Kim, Dae Hyun;
Yi Lu;
Perdomo, German;
Qu, Shen;
Slusher, Sandra;
Tse, Hubert M.;
Piganelli, Jon;
Giannoukakis, Nick;
Zhang, Jian;
Dong, H. Henry

Publication type:

Article

A Microsphere-Based Vaccine Prevents and Reverses New-Onset Autoimmune Diabetes.

Published in:

Diabetes, 2008, v. 57, n. 6, p. 1544, doi. 10.2337/db07-0507

By:

Phillips, Brett;
Nylander, Karen;
Harnaha, Jo;
Machen, Jennifer;
Lakomy, Robert;
Styche, Alexis;
Gillis, Kimberly;
Brown, Larry;
Lafreniere, Debra;
Gallo, Michael;
Knox, Janet;
Hogeland, Kenneth;
Trucco, Massimo;
Giannoukakis, Nick

Publication type:

Article

Prevention and Reversal of Autoimmune Diabetes by Microsphere-Formulated Oligonucleotides.

Published in:

Diabetes, 2007, v. 56, p. A81

By:

Nylander, Karen;
Harnaha, Jo;
Gillis, Kimberly;
Brown, Larry;
Trucco, Massimo;
Giannoukakis, Nick

Publication type:

Article

Interleukin-7 Is a Survival Factor for CD4<sup>+</sup> CD25<sup>+</sup> T-Cells and Is Expressed by Diabetes-Suppressive Dendritic Cells.

Published in:

Diabetes, 2006, v. 55, n. 1, p. 158, doi. 10.2337/diabetes.55.01.06.db05-0340

By:

Harnaha, Jo;
Machen, Jennifer;
Wright, Marietta;
Lakomy, Robert;
Styche, Alexis;
Trucco, Massimo;
Makaroun, Sami;
Giannoukakis, Nick

Publication type:

Article

Prevention of diabetes in NOD mice by administration of dendritic cells deficient in nuclear transcription factor-kappaB activity.

Published in:

2003

By:

Ma, Linlin;
Linlin Ma;
Qian, Shiguang;
Shiguang Qian;
Xiaoyan Liang;
Liang, Xiaoyan;
Wang, Lianfu;
Lianfu Wang;
Woodward, Jennifer E.;
Giannoukakis, Nick;
Robbins, Paul D.;
Bertera, Suzanne;
Trucco, Massimo;
Fung, John J.;
Lina Lu;
Lu, Lina

Publication type:

journal article

Targeting Autoimmune Diabetes With Gene Therapy.

Published in:

Diabetes, 1999, v. 48, n. 11, p. 2107, doi. 10.2337/diabetes.48.11.2107

By:

Giannoukakis, Nick;
Rudert, William A.;
Robbins, Paul D.;
Trucco, Massimo

Publication type:

Article

Adenoviral gene transfer of the interleukin-1 receptor antagonist protein to human islets prevents IL-1beta-induced beta-cell impairment and activation of islet cell apoptosis in vitro.

Published in:

1999

By:

Giannoukakis, Nick;
Rudert, William A.;
Ghivizzani, Steve C.;
Gambotto, Andrea;
Ricordi, Camillo;
Trucco, Massimo;
Robbins, Paul D.;
Giannoukakis, N;
Rudert, W A;
Ghivizzani, S C;
Gambotto, A;
Ricordi, C;
Trucco, M;
Robbins, P D

Publication type:

journal article

Clinical Tolerogenic Dendritic Cells: Exploring Therapeutic Impact on Human Autoimmune Disease.

Published in:

Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01279

By:

Phillips, Brett Eugene;
Garciafigueroa, Yesica;
Trucco, Massimo;
Giannoukakis, Nick

Publication type:

Article

Involvement of Suppressive B-Lymphocytes in the Mechanism of Tolerogenic Dendritic Cell Reversal of Type 1 Diabetes in NOD Mice.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0083575

By:

Di Caro, Valentina;
Phillips, Brett;
Engman, Carl;
Harnaha, Jo;
Trucco, Massimo;
Giannoukakis, Nick

Publication type:

Article

Identification of a Cardiac Specific Protein Transduction Domain by In Vivo Biopanning Using a M13 Phage Peptide Display Library in Mice.

Published in:

PLoS ONE, 2010, v. 5, n. 8, p. 1, doi. 10.1371/journal.pone.0012252

By:

Zahid, Maliha;
Phillips, Brett E.;
Albers, Sean M.;
Giannoukakis, Nick;
Watkins, Simon C.;
Robbins, Paul D.

Publication type:

Article

Current Status and Prospects for Gene and Cell Therapeutics for Type 1 Diabetes Mellitus.

Published in:

Reviews in Endocrine & Metabolic Disorders, 2003, v. 4, n. 4, p. 369

By:

Nick Giannoukakis;
Massimo Trucco

Publication type:

Article

Dendritic cell-based therapy in Type 1 diabetes mellitus.

Published in:

Expert Review of Clinical Immunology, 2009, v. 5, n. 3, p. 325, doi. 10.1586/eci.09.8

By:

Phillips, Brett;
Giannoukakis, Nick;
Trucco, Massimo

Publication type:

Article

Response to Comment on Pietropaolo et al. Incidence of an Insulin-Requiring Hyperglycemic Syndrome in SARS-CoV-2– Infected Young Individuals: Is It Type 1 Diabetes? Diabetes 2022;71:2656–2663.

Published in:

2022

By:

Pietropaolo, Massimo;
Hotez, Peter;
Giannoukakis, Nick

Publication type:

Letter

Incidence of an Insulin-Requiring Hyperglycemic Syndrome in SARS-CoV-2–Infected Young Individuals: Is It Type 1 Diabetes?

Published in:

Diabetes, 2022, v. 71, n. 12, p. 2656, doi. 10.2337/db21-0831

By:

Pietropaolo, Massimo;
Hotez, Peter;
Giannoukakis, Nick

Publication type:

Article

Modulation of Leukocytes of the Innate Arm of the Immune System as a Potential Approach to Prevent the Onset and Progression of Type 1 Diabetes.

Published in:

2021

By:

Petrelli, Alessandra;
Atkinson, Mark A.;
Pietropaolo, Massimo;
Giannoukakis, Nick

Publication type:

journal article

Phosphatidylinositol-3-kinase activity during in vitro dendritic cell generation determines suppressive or stimulatory capacity.

Published in:

Immunologic Research, 2011, v. 50, n. 2/3, p. 130, doi. 10.1007/s12026-011-8206-1

By:

Di Caro, Valentina;
D'Anneo, Antonella;
Phillips, Brett;
Engman, Carl;
Harnaha, Jo;
Trucco, Massimo;
Giannoukakis, Nick

Publication type:

Article