Found: 27

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  • Desmoplastic Reaction, Immune Cell Response, and Prognosis in Colorectal Cancer.

    Published in:
    Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.840198
    By:
    • Akimoto, Naohiko;
    • Väyrynen, Juha P.;
    • Zhao, Melissa;
    • Ugai, Tomotaka;
    • Fujiyoshi, Kenji;
    • Borowsky, Jennifer;
    • Zhong, Rong;
    • Haruki, Koichiro;
    • Arima, Kota;
    • Lau, Mai Chan;
    • Kishikawa, Junko;
    • Twombly, Tyler S.;
    • Takashima, Yasutoshi;
    • Song, Mingyang;
    • Zhang, Xuehong;
    • Wu, Kana;
    • Chan, Andrew T.;
    • Meyerhardt, Jeffrey A.;
    • Giannakis, Marios;
    • Nowak, Jonathan A.
    Publication type:
    Article

  • Histopathology images predict multi-omics aberrations and prognoses in colorectal cancer patients.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37179-4
    By:
    • Tsai, Pei-Chen;
    • Lee, Tsung-Hua;
    • Kuo, Kun-Chi;
    • Su, Fang-Yi;
    • Lee, Tsung-Lu Michael;
    • Marostica, Eliana;
    • Ugai, Tomotaka;
    • Zhao, Melissa;
    • Lau, Mai Chan;
    • Väyrynen, Juha P.;
    • Giannakis, Marios;
    • Takashima, Yasutoshi;
    • Kahaki, Seyed Mousavi;
    • Wu, Kana;
    • Song, Mingyang;
    • Meyerhardt, Jeffrey A.;
    • Chan, Andrew T.;
    • Chiang, Jung-Hsien;
    • Nowak, Jonathan;
    • Ogino, Shuji
    Publication type:
    Article

  • Conversions of olive mill wastewater-based media by Saccharomyces cerevisiae through sterile and non-sterile bioprocesses.

    Published in:
    Journal of Chemical Technology & Biotechnology, 2013, v. 88, n. 5, p. 958, doi. 10.1002/jctb.3931
    By:
    • Sarris, Dimitris;
    • Giannakis, Marios;
    • Philippoussis, Antonios;
    • Komaitis, Michael;
    • Koutinas, Apostolis A.;
    • Papanikolaou, Seraphim
    Publication type:
    Article

  • Vitamin C intake and colorectal cancer survival according to KRAS and BRAF mutation: a prospective study in two US cohorts.

    Published in:
    British Journal of Cancer, 2023, v. 129, n. 11, p. 1793, doi. 10.1038/s41416-023-02452-2
    By:
    • Shi, Shanshan;
    • Wang, Kai;
    • Ugai, Tomotaka;
    • Giannakis, Marios;
    • Cazaubiel, Jules;
    • Chan, Andrew T.;
    • Giovannucci, Edward L.;
    • Nowak, Jonathan A.;
    • Meyerhardt, Jeffrey A.;
    • Ogino, Shuji;
    • Song, Mingyang
    Publication type:
    Article

  • Phase 1 study of single-agent WNT974, a first-in-class Porcupine inhibitor, in patients with advanced solid tumours.

    Published in:
    2021
    By:
    • Rodon, Jordi;
    • Argilés, Guillem;
    • Connolly, Roisin M.;
    • Vaishampayan, Ulka;
    • de Jonge, Maja;
    • Garralda, Elena;
    • Giannakis, Marios;
    • Smith, David C.;
    • Dobson, Jason R.;
    • McLaughlin, Margaret E.;
    • Seroutou, Abdelkader;
    • Ji, Yan;
    • Morawiak, Jennifer;
    • Moody, Susan E.;
    • Janku, Filip
    Publication type:
    journal article

  • RNF43 is frequently mutated in colorectal and endometrial cancers.

    Published in:
    Nature Genetics, 2014, v. 46, n. 12, p. 1264, doi. 10.1038/ng.3127
    By:
    • Giannakis, Marios;
    • Van Allen, Eliezer M;
    • Hahn, William C;
    • Garraway, Levi A;
    • Fuchs, Charles S;
    • Hodis, Eran;
    • Jasmine Mu, Xinmeng;
    • Rosenbluh, Joseph;
    • Yamauchi, Mai;
    • Qian, Zhi Rong;
    • Cibulskis, Kristian;
    • Saksena, Gordon;
    • Lawrence, Michael S;
    • Gabriel, Stacey B;
    • Nishihara, Reiko;
    • Lander, Eric S;
    • Getz, Gad;
    • Ogino, Shuji
    Publication type:
    Article

  • Alcohol and colorectal cancer risk, subclassified by mutational signatures of DNA mismatch repair deficiency.

    Published in:
    JNCI: Journal of the National Cancer Institute, 2024, v. 116, n. 8, p. 1255, doi. 10.1093/jnci/djae078
    By:
    • Fang, Aiping;
    • Ugai, Tomotaka;
    • Gurjao, Carino;
    • Zhong, Rong;
    • Liu, Zhenhua;
    • Zhang, Xinyuan;
    • Wang, Peilu;
    • Nowak, Jonathan;
    • Wang, Molin;
    • Giannakis, Marios;
    • Ogino, Shuji;
    • Zhang, Xuehong;
    • Giovannucci, Edward
    Publication type:
    Article

  • Smoking and Incidence of Colorectal Cancer Subclassified by Tumor-Associated Macrophage Infiltrates.

    Published in:
    2022
    By:
    • Ugai, Tomotaka;
    • Väyrynen, Juha P;
    • Haruki, Koichiro;
    • Akimoto, Naohiko;
    • Lau, Mai Chan;
    • Zhong, Rong;
    • Kishikawa, Junko;
    • Väyrynen, Sara A;
    • Zhao, Melissa;
    • Fujiyoshi, Kenji;
    • Costa, Andressa Dias;
    • Borowsky, Jennifer;
    • Arima, Kota;
    • Guerriero, Jennifer L;
    • Fuchs, Charles S;
    • Zhang, Xuehong;
    • Song, Mingyang;
    • Wang, Molin;
    • Giannakis, Marios;
    • Meyerhardt, Jeffrey A
    Publication type:
    journal article

  • Smoking and Risk of Colorectal Cancer Sub-Classified by Tumor-Infiltrating T Cells.

    Published in:
    2019
    By:
    • Hamada, Tsuyoshi;
    • Nowak, Jonathan A;
    • Masugi, Yohei;
    • Drew, David A;
    • Song, Mingyang;
    • Cao, Yin;
    • Kosumi, Keisuke;
    • Mima, Kosuke;
    • Twombly, Tyler S;
    • Liu, Li;
    • Shi, Yan;
    • Silva, Annacarolina da;
    • Gu, Mancang;
    • Li, Wanwan;
    • Nosho, Katsuhiko;
    • Keum, NaNa;
    • Giannakis, Marios;
    • Meyerhardt, Jeffrey A;
    • Wu, Kana;
    • Wang, Molin
    Publication type:
    journal article

  • Fusobacterium nucleatum in Colorectal Carcinoma Tissue According to Tumor Location.

    Published in:
    Clinical & Translational Gastroenterology, 2016, v. 7, n. 11, p. e200, doi. 10.1038/ctg.2016.53
    By:
    • Mima, Kosuke;
    • Cao, Yin;
    • Chan, Andrew T;
    • Qian, Zhi Rong;
    • Nowak, Jonathan A;
    • Masugi, Yohei;
    • Shi, Yan;
    • Song, Mingyang;
    • da Silva, Annacarolina;
    • Gu, Mancang;
    • Li, Wanwan;
    • Hamada, Tsuyoshi;
    • Kosumi, Keisuke;
    • Hanyuda, Akiko;
    • Liu, Li;
    • Kostic, Aleksandar D;
    • Giannakis, Marios;
    • Bullman, Susan;
    • Brennan, Caitlin A;
    • Milner, Danny A
    Publication type:
    Article

  • Healthy and unhealthy plant‐based diets in relation to the incidence of colorectal cancer overall and by molecular subtypes.

    Published in:
    Clinical & Translational Medicine, 2022, v. 12, n. 8, p. 1, doi. 10.1002/ctm2.893
    By:
    • Wang, Fenglei;
    • Ugai, Tomotaka;
    • Haruki, Koichiro;
    • Wan, Yi;
    • Akimoto, Naohiko;
    • Arima, Kota;
    • Zhong, Rong;
    • Twombly, Tyler S.;
    • Wu, Kana;
    • Yin, Kanhua;
    • Chan, Andrew T.;
    • Giannakis, Marios;
    • Nowak, Jonathan A.;
    • Meyerhardt, Jeffrey A.;
    • Liang, Liming;
    • Song, Mingyang;
    • Smith‐Warner, Stephanie A.;
    • Zhang, Xuehong;
    • Giovannucci, Edward L.;
    • Willett, Walter C.
    Publication type:
    Article

  • Phase Ib and Expansion Study of Gemcitabine, Nab-Paclitaxel, and Ficlatuzumab in Patients With Metastatic Pancreatic Cancer.

    Published in:
    Oncologist, 2023, v. 28, n. 5, p. 425, doi. 10.1093/oncolo/oyad002
    By:
    • Perez, Kimberly;
    • Chiarella, Anna M;
    • Cleary, James M;
    • Horick, Nora;
    • Weekes, Colin;
    • Abrams, Thomas;
    • Blaszkowsky, Lawrence;
    • Enzinger, Peter;
    • Giannakis, Marios;
    • Goyal, Lipika;
    • Meyerhardt, Jeffrey A;
    • Rubinson, Douglas;
    • Yurgelun, Matthew B;
    • Goessling, Wolfram;
    • Giantonio, Bruce J;
    • Brais, Lauren;
    • Germon, Victoria;
    • Stonely, Danielle;
    • Raghavan, Srivatsan;
    • Bakir, Basil
    Publication type:
    Article

  • RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30794-7
    By:
    • Fang, Lishan;
    • Ford-Roshon, Dane;
    • Russo, Max;
    • O'Brien, Casey;
    • Xiong, Xiaozhe;
    • Gurjao, Carino;
    • Grandclaudon, Maximilien;
    • Raghavan, Srivatsan;
    • Corsello, Steven M.;
    • Carr, Steven A.;
    • Udeshi, Namrata D.;
    • Berstler, James;
    • Sicinska, Ewa;
    • Ng, Kimmie;
    • Giannakis, Marios
    Publication type:
    Article

  • Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade.

    Published in:
    2021
    By:
    • Sehgal, Kartik;
    • Portell, Andrew;
    • Ivanova, Elena V.;
    • Lizotte, Patrick H.;
    • Mahadevan, Navin R.;
    • Greene, Jonathan R.;
    • Vajdi, Amir;
    • Gurjao, Carino;
    • Teceno, Tyler;
    • Taus, Luke J.;
    • Thai, Tran C.;
    • Shunsuke Kitajima;
    • Liu, Derek;
    • Tetsuo Tani;
    • Noureddine, Moataz;
    • Lau, Christie J.;
    • Kirschmeier, Paul T.;
    • Liu, David;
    • Giannakis, Marios;
    • Jenkins, Russell W.
    Publication type:
    journal article

  • Cancer Diagnoses After Recent Weight Loss.

    Published in:
    JAMA: Journal of the American Medical Association, 2024, v. 331, n. 4, p. 318, doi. 10.1001/jama.2024.5419
    By:
    • Wang, Qiao-Li;
    • Babic, Ana;
    • Rosenthal, Michael H.;
    • Lee, Alice A.;
    • Zhang, Yin;
    • Zhang, Xuehong;
    • Song, Mingyang;
    • Rezende, Leandro F. M.;
    • Lee, Dong Hoon;
    • Biller, Leah;
    • Ng, Kimmie;
    • Giannakis, Marios;
    • Chan, Andrew T.;
    • Meyerhardt, Jeffrey A.;
    • Fuchs, Charles S.;
    • Eliassen, A. Heather;
    • Birmann, Brenda M.;
    • Stampfer, Meir J.;
    • Giovannucci, Edward L.;
    • Kraft, Peter
    Publication type:
    Article

  • The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine.

    Published in:
    Genome Medicine, 2016, v. 8, p. 1, doi. 10.1186/s13073-016-0333-9
    By:
    • Garofalo, Andrea;
    • Sholl, Lynette;
    • Reardon, Brendan;
    • Taylor-Weiner, Amaro;
    • Amin-Mansour, Ali;
    • Miao, Diana;
    • Liu, David;
    • Oliver, Nelly;
    • MacConaill, Laura;
    • Ducar, Matthew;
    • Rojas-Rudilla, Vanesa;
    • Giannakis, Marios;
    • Ghazani, Arezou;
    • Gray, Stacy;
    • Janne, Pasi;
    • Garber, Judy;
    • Joffe, Steve;
    • Lindeman, Neal;
    • Wagle, Nikhil;
    • Garraway, Levi A.
    Publication type:
    Article

  • Proceedings of the fourth international molecular pathological epidemiology (MPE) meeting.

    Published in:
    2019
    By:
    • Campbell, Peter T.;
    • Ambrosone, Christine B.;
    • Nishihara, Reiko;
    • Aerts, Hugo J. W. L.;
    • Bondy, Melissa;
    • Chatterjee, Nilanjan;
    • Garcia-Closas, Montserrat;
    • Giannakis, Marios;
    • Golden, Jeffrey A.;
    • Heng, Yujing J.;
    • Kip, N. Sertac;
    • Koshiol, Jill;
    • Liu, X. Shirley;
    • Lopes-Ramos, Camila M.;
    • Mucci, Lorelei A.;
    • Nowak, Jonathan A.;
    • Phipps, Amanda I.;
    • Quackenbush, John;
    • Schoen, Robert E.;
    • Sholl, Lynette M.
    Publication type:
    journal article

  • Association Between Smoking and Molecular Subtypes of Colorectal Cancer.

    Published in:
    JNCI Cancer Spectrum, 2021, v. 5, n. 4, p. 1, doi. 10.1093/jncics/pkab056
    By:
    • Wang, Xiaoliang;
    • Amitay, Efrat;
    • Harrison, Tabitha A;
    • Banbury, Barbara L;
    • Berndt, Sonja I;
    • Brenner, Hermann;
    • Buchanan, Daniel D;
    • Campbell, Peter T;
    • Cao, Yin;
    • Chan, Andrew T;
    • Chang-Claude, Jenny;
    • Gallinger, Steven J;
    • Giannakis, Marios;
    • Giles, Graham G;
    • Gunter, Marc J;
    • Hopper, John L;
    • Jenkins, Mark A;
    • Lin, Yi;
    • Moreno, Victor;
    • Nishihara, Reiko
    Publication type:
    Article

  • Coffee Intake and Colorectal Cancer Incidence According to T-Cell Response.

    Published in:
    JNCI Cancer Spectrum, 2020, v. 4, n. 6, p. 1, doi. 10.1093/jncics/pkaa068
    By:
    • Ugai, Tomotaka;
    • Haruki, Koichiro;
    • Väyrynen, Juha P;
    • Zhong, Rong;
    • Borowsky, Jennifer;
    • Fujiyoshi, Kenji;
    • Lau, Mai Chan;
    • Zhao, Melissa;
    • Akimoto, Naohiko;
    • Chang, Tzuu-Wang;
    • Kishikawa, Junko;
    • Arima, Kota;
    • Shi, Shan-Shan;
    • Gu, Simeng;
    • Fuchs, Charles S;
    • Giovannucci, Edward L;
    • Giannakis, Marios;
    • Zhang, Xuehong;
    • Song, Mingyang;
    • Meyerhardt, Jeffrey A
    Publication type:
    Article

  • Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17386-z
    By:
    • Zaidi, Syed H.;
    • Harrison, Tabitha A.;
    • Phipps, Amanda I.;
    • Steinfelder, Robert;
    • Trinh, Quang M.;
    • Qu, Conghui;
    • Banbury, Barbara L.;
    • Georgeson, Peter;
    • Grasso, Catherine S.;
    • Giannakis, Marios;
    • Adams, Jeremy B.;
    • Alwers, Elizabeth;
    • Amitay, Efrat L.;
    • Barfield, Richard T.;
    • Berndt, Sonja I.;
    • Borozan, Ivan;
    • Brenner, Hermann;
    • Brezina, Stefanie;
    • Buchanan, Daniel D.;
    • Cao, Yin
    Publication type:
    Article

  • Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15111-4
    By:
    • Rendo, Veronica;
    • Stoimenov, Ivaylo;
    • Mateus, André;
    • Sjöberg, Elin;
    • Svensson, Richard;
    • Gustavsson, Anna-Lena;
    • Johansson, Lars;
    • Ng, Adrian;
    • OʼBrien, Casey;
    • Giannakis, Marios;
    • Artursson, Per;
    • Nygren, Peter;
    • Cheong, Ian;
    • Sjöblom, Tobias
    Publication type:
    Article

  • Tumor Long Interspersed Nucleotide Element-1 (LINE-1) Hypomethylation in Relation to Age of Colorectal Cancer Diagnosis and Prognosis.

    Published in:
    Cancers, 2021, v. 13, n. 9, p. 2016, doi. 10.3390/cancers13092016
    By:
    • Akimoto, Naohiko;
    • Zhao, Melissa;
    • Ugai, Tomotaka;
    • Zhong, Rong;
    • Lau, Mai Chan;
    • Fujiyoshi, Kenji;
    • Kishikawa, Junko;
    • Haruki, Koichiro;
    • Arima, Kota;
    • Twombly, Tyler S.;
    • Zhang, Xuehong;
    • Giovannucci, Edward L.;
    • Wu, Kana;
    • Song, Mingyang;
    • Chan, Andrew T.;
    • Cao, Yin;
    • Meyerhardt, Jeffrey A.;
    • Ng, Kimmie;
    • Giannakis, Marios;
    • Väyrynen, Juha P.
    Publication type:
    Article

  • Association between germline variants and somatic mutations in colorectal cancer.

    Published in:
    Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-14408-2
    By:
    • Barfield, Richard;
    • Qu, Conghui;
    • Steinfelder, Robert S.;
    • Zeng, Chenjie;
    • Harrison, Tabitha A.;
    • Brezina, Stefanie;
    • Buchanan, Daniel D.;
    • Campbell, Peter T.;
    • Casey, Graham;
    • Gallinger, Steven;
    • Giannakis, Marios;
    • Gruber, Stephen B.;
    • Gsur, Andrea;
    • Hsu, Li;
    • Huyghe, Jeroen R.;
    • Moreno, Victor;
    • Newcomb, Polly A.;
    • Ogino, Shuji;
    • Phipps, Amanda I.;
    • Slattery, Martha L.
    Publication type:
    Article

  • Diabetes mellitus in relation to colorectal tumor molecular subtypes: A pooled analysis of more than 9000 cases.

    Published in:
    International Journal of Cancer, 2022, v. 151, n. 3, p. 348, doi. 10.1002/ijc.34015
    By:
    • Harlid, Sophia;
    • Van Guelpen, Bethany;
    • Qu, Conghui;
    • Gylling, Björn;
    • Aglago, Elom K.;
    • Amitay, Efrat L.;
    • Brenner, Hermann;
    • Buchanan, Daniel D.;
    • Campbell, Peter T.;
    • Cao, Yin;
    • Chan, Andrew T.;
    • Chang‐Claude, Jenny;
    • Drew, David A.;
    • Figueiredo, Jane C.;
    • French, Amy J.;
    • Gallinger, Steven;
    • Giannakis, Marios;
    • Giles, Graham G.;
    • Gunter, Marc J.;
    • Hoffmeister, Michael
    Publication type:
    Article

  • Family history of cancer, Ashkenazi Jewish ancestry, and pancreatic cancer risk.

    Published in:
    2019
    By:
    • Hamada, Tsuyoshi;
    • Yuan, Chen;
    • Yurgelun, Matthew B.;
    • Perez, Kimberly;
    • Khalaf, Natalia;
    • Morales-Oyarvide, Vicente;
    • Babic, Ana;
    • Nowak, Jonathan A.;
    • Rubinson, Douglas A.;
    • Giannakis, Marios;
    • Ng, Kimmie;
    • Kraft, Peter;
    • Stampfer, Meir J.;
    • Giovannucci, Edward L.;
    • Fuchs, Charles S.;
    • Ogino, Shuji;
    • Wolpin, Brian M.
    Publication type:
    journal article

  • Germline genetic regulation of the colorectal tumor immune microenvironment.

    Published in:
    BMC Genomics, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12864-024-10295-1
    By:
    • Schmit, Stephanie L.;
    • Tsai, Ya-Yu;
    • Bonner, Joseph D.;
    • Sanz-Pamplona, Rebeca;
    • Joshi, Amit D.;
    • Ugai, Tomotaka;
    • Lindsey, Sidney S.;
    • Melas, Marilena;
    • McDonnell, Kevin J.;
    • Idos, Gregory E.;
    • Walker, Christopher P.;
    • Qu, Chenxu;
    • Kast, W. Martin;
    • Da Silva, Diane M.;
    • Glickman, Jonathan N.;
    • Chan, Andrew T.;
    • Giannakis, Marios;
    • Nowak, Jonathan A.;
    • Rennert, Hedy S.;
    • Robins, Harlan S.
    Publication type:
    Article

  • eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants.

    Published in:
    PLoS Computational Biology, 2021, v. 17, n. 7, p. 1, doi. 10.1371/journal.pcbi.1009132
    By:
    • Thornton, Alexis M.;
    • Fang, Lishan;
    • Lo, April;
    • McSharry, Maria;
    • Haan, David;
    • O'Brien, Casey;
    • Berger, Alice H.;
    • Giannakis, Marios;
    • Brooks, Angela N.
    Publication type:
    Article