Works matching AU Gi-Wook Hwang

Results: 55

Aggregability of the SQSTM1/p62-based aggresome-like induced structures determines the sensitivity to parthanatos.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01838-2

By:

Hamano, Shuhei;
Noguchi, Takuya;
Asai, Yukino;
Ito, Ryo;
Komatsu, Ryuto;
Sato, Tetsu;
Inoue, Aya;
Maruyama, Tomoe;
Kudo, Tada-aki;
Hirata, Yusuke;
Shindo, Sawako;
Uchida, Yasuo;
Hwang, Gi-Wook;
Matsuzawa, Atsushi

Publication type:

Article

The protein transportation pathway from Golgi to vacuoles via endosomes plays a role in enhancement of methylmercury toxicity.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep05888

By:

Gi-Wook Hwang;
Yasutaka Murai;
Tsutomu Takahashi;
Akira Naganuma

Publication type:

Article

Immature Core protein of hepatitis C virus induces an unfolded protein response through inhibition of ERAD-L in a yeast model system.

Published in:

Genes to Cells, 2017, v. 22, n. 2, p. 160, doi. 10.1111/gtc.12464

By:

Takahashi, Shota;
Sato, Naoko;
Kikuchi, Junichi;
Kakinuma, Hideaki;
Okawa, Jun;
Masuyama, Yukiko;
Iwasa, Singo;
Irokawa, Hayato;
Hwang, Gi‐Wook;
Naganuma, Akira;
Kohara, Michinori;
Kuge, Shusuke

Publication type:

Article

Methylmercury directly modifies the 105th cysteine residue in oncostatin M to promote binding to tumor necrosis factor receptor 3 and inhibit cell growth.

Published in:

Archives of Toxicology, 2023, v. 97, n. 7, p. 1887, doi. 10.1007/s00204-023-03520-5

By:

Toyama, Takashi;
Xu, Sidi;
Kanemitsu, Yoshitomi;
Hasegawa, Takashi;
Noguchi, Takuya;
Lee, Jin-Yong;
Matsuzawa, Atsushi;
Naganuma, Akira;
Hwang, Gi-Wook

Publication type:

Article

The Nuclear Protein HOXB13 Enhances Methylmercury Toxicity by Inducing OncostatinM and Promoting Its Binding to TNFR3 in Cultured Cells.

Published in:

Cells (2073-4409), 2020, v. 9, n. 1, p. 1, doi. 10.3390/cells9010045

By:

Takashi Toyama;
Sidi Xu;
Ryo Nakano;
Takashi Hasegawa;
Naoki Endo;
Tsutomu Takahashi;
Jin-Yong Lee;
Akira Naganuma;
Gi-Wook Hwang

Publication type:

Article

Identification of substrates of F-box protein involved in methylmercury toxicity in yeast cells.

Published in:

FEBS Letters, 2015, v. 589, n. 19PartB, p. 2720, doi. 10.1016/j.febslet.2015.08.016

By:

Lee, Jin-Yong;
Ishida, Yosuke;
Kuge, Shusuke;
Naganuma, Akira;
Hwang, Gi-Wook

Publication type:

Article

Development of an adenovirus-mediated reporter assay system to detect a low concentration of retinoic acid in MCF-7 cells.

Published in:

Journal of Toxicological Sciences, 2022, v. 47, n. 6, p. 249, doi. 10.2131/jts.47.249

By:

Sawako Shindo;
Anari Shioya;
Michiko Watanabe;
Takamitsu Sasaki;
Hiroyuki Suzuki;
Takeshi Kumagai;
Gi-Wook Hwang;
Kiyoshi Nagata

Publication type:

Article

Evaluation of M1-microglial activation by neurotoxic metals using optimized organotypic cerebral slice cultures.

Published in:

Journal of Toxicological Sciences, 2019, v. 44, n. 7, p. 471, doi. 10.2131/jts.44.471

By:

Takayuki Hoshi;
Takashi Toyama;
Youichi Shinozaki;
Schuichi Koizumi;
Jin-Yong Lee;
Akira Naganuma;
Gi-Wook Hwang

Publication type:

Article

Lethal chronotoxicity induced by seven metal compounds in mice.

Published in:

Journal of Toxicological Sciences, 2018, v. 43, n. 2, p. 129, doi. 10.2131/jts.43.129

By:

Hiroki Yoshioka;
Tsunemasa Nonogaki;
Yasuro Shinohara;
Masumi Suzui;
Yurie Mori;
Gi-Wook Hwang;
Katsumi Ohtani;
Nobuhiko Miura

Publication type:

Article

Effects of long-term cadmium exposure on urinary metabolite profiles in mice.

Published in:

Journal of Toxicological Sciences, 2018, v. 43, n. 2, p. 89, doi. 10.2131/jts.43.89

By:

Sarma, Sailendra Nath;
Saleem, Ammar;
Jin-Yong Lee;
Maki Tokumoto;
Gi-Wook Hwang;
Hing Man Chan;
Masahiko Satoh

Publication type:

Article

Multidirectional analyses of hepatic chronotoxicity induced by cadmium in mice.

Published in:

Journal of Toxicological Sciences, 2017, v. 42, n. 5, p. 597, doi. 10.2131/jts.42.597

By:

Nobuhiko Miura;
Hiroki Yoshioka;
Atsushige Ashimori;
Katsumi Ohtani;
Tatsuya Hasegawa;
Gi-Wook Hwang;
Masayuki Ikeda;
Tsunemasa Nonogaki

Publication type:

Article

High sensitivity of testicular function to titanium nanoparticles.

Published in:

Journal of Toxicological Sciences, 2017, v. 42, n. 3, p. 359, doi. 10.2131/jts.42.359

By:

Nobuhiko Miura;
Katsumi Ohtani;
Tatsuya Hasegawa;
Hiroki Yoshioka;
Gi-Wook Hwang

Publication type:

Article

Chronotoxicity of bromobenzene-induced hepatic injury in mice.

Published in:

Journal of Toxicological Sciences, 2017, v. 42, n. 2, p. 251, doi. 10.2131/jts.42.251

By:

Hiroki Yoshioka;
Tsunemasa Nonogaki;
Nobuyuki Fukuishi;
Yasuro Shinohara;
Gi-Wook Hwang;
Katsumi Ohtani;
Nobuhiko Miura

Publication type:

Article

Adverse health effects of humidifier disinfectants in Korea: lung toxicity of polyhexamethylene guanidine phosphate.

Published in:

Journal of Toxicological Sciences, 2016, v. 41, n. 6, p. 711, doi. 10.2131/jts.41.711

By:

Ha-Ryong Kim;
Gi-Wook Hwang;
Akira Naganuma;
Kyu-Hyuck Chung

Publication type:

Article

FBXO6 attenuates cadmium toxicity in HEK293 cells by inhibiting ER stress and JNK activation.

Published in:

Journal of Toxicological Sciences, 2014, v. 39, n. 6, p. 861, doi. 10.2131/jts.39.861

By:

Ke Du;
Tsutomu Takahashi;
Shusuke Kuge;
Akira Naganuma;
Gi-Wook Hwang

Publication type:

Article

Brain-specific induction of secretoglobin 3A1 expression in mice treated with methylmercury.

Published in:

Journal of Toxicological Sciences, 2013, v. 38, n. 6, p. 963, doi. 10.2131/jts.38.963

By:

Takahashi, Tsutomo;
Kim, Min-Seok;
Saito, Takahiro;
Lee, Jin-Yong;
Hwang, Gi-Wook;
Naganuma, Akira

Publication type:

Article

Global chemokine expression in methylmercury-treated mice: methylmercury induces brain-specific expression of CCL3 and CCL4.

Published in:

Journal of Toxicological Sciences, 2013, v. 38, n. 6, p. 925, doi. 10.2131/jts.38.925

By:

Kim, Min-Seok;
Takahashi, Tsutomu;
Lee, Jin-Yong;
Hwang, Gi-Wook;
Naganuma, Akira

Publication type:

Article

Knockdown of the gene for homeobox protein HOXB13 reduces toxicity of oxidative-stress inducers in HEK293 cells.

Published in:

Journal of Toxicological Sciences, 2013, v. 38, n. 6, p. 821, doi. 10.2131/jts.38.821

By:

Nakano, Ryo;
Takahashi, Tsutomu;
Naganuma, Akira;
Hwang, Gi-Wook

Publication type:

Article

Changes in the levels of low molecular weight metabolites in the mouse cerebellum following treatment with methylmercury.

Published in:

Journal of Toxicological Sciences, 2013, v. 38, n. 5, p. 703, doi. 10.2131/jts.38.703

By:

Gi-Wook Hwang;
Jin-Yong Lee;
Min-Seok Kim;
Masayuki Sato;
Tsutomu Takahashi;
Akira Naganuma

Publication type:

Article

Deletion of the ubiquitin-conjugating enzyme Ubc2 confers resistance to methylmercury in budding yeast by promoting Whi2 degradation.

Published in:

Journal of Toxicological Sciences, 2013, v. 38, n. 2, p. 301, doi. 10.2131/jts.38.301

By:

Gi-Wook Hwang;
Fujio Mastuyama;
Tsutomu Takahashi;
Jin-Yong Lee;
Akira Naganuma

Publication type:

Article

Identification of deubiquitinating enzymes involved in methylmercury toxicity in Saccharomyces cerevisiae.

Published in:

Journal of Toxicological Sciences, 2012, v. 37, n. 6, p. 1287, doi. 10.2131/jts.37.1287

By:

Gi-Wook Hwang;
Yukiyoshi Kimura;
Tsutomu Takahashi;
Jin-Yong Lee;
Akira Naganuma

Publication type:

Article

Ubiquitin-conjugating enzyme Cdc34 mediates methylmercury resistance in Saccharomyces cerevisiae by increasing Whi2 degradation.

Published in:

Journal of Toxicological Sciences, 2012, v. 37, n. 6, p. 1283, doi. 10.2131/jts.37.1283

By:

Gi-Wook Hwang;
Yousuke Ogiwara;
Tsutomu Takahashi;
Akira Naganuma

Publication type:

Article

Methylmercury induces a brain-specific increase in chemokine CCL4 expression in mice.

Published in:

Journal of Toxicological Sciences, 2012, v. 37, n. 6, p. 1278, doi. 10.2131/jts.37.1279

By:

Jin-Yong Lee;
Gi-Wook Hwang;
Min-Seok Kim;
Tsutomu Takahashi;
Akira Naganuma

Publication type:

Article

Methylmercury induces CCL2 expression through activation of NF-κB in human 1321N1 astrocytes.

Published in:

Journal of Toxicological Sciences, 2012, v. 37, n. 6, p. 1275, doi. 10.2131/jts.37.1275

By:

Min-Seok Kim;
Tsutomu Takahashi;
Jin-Yong Lee;
Gi-Wook Hwang;
Akira Naganuma

Publication type:

Article

Increased production of reactive oxygen species by the vacuolar-type (H<sup>+</sup>)-ATPase inhibitors bafilomycin A1 and concanamycin A in RAW 264 cells.

Published in:

Journal of Toxicological Sciences, 2012, v. 37, n. 5, p. 1045, doi. 10.2131/jts.37.1045

By:

Aya Yokomakura;
JangJa Hong;
Kazuo Ohuchi;
Seong-Eun Oh;
Jin-Yong Lee;
Nariyasu Mano;
Tsutomu Takahashi;
Gi-Wook Hwang;
Akira Naganuma

Publication type:

Article

A screening for essential cell growth-related genes involved in arsenite toxicity in Saccharomyces cerevisiae.

Published in:

Journal of Toxicological Sciences, 2011, v. 36, n. 6, p. 859, doi. 10.2131/jts.36.859

By:

Takahashi, Tsutomu;
Satake, Shohei;
Hirose, Ken-ichiro;
Gi-Wook Hwang;
Naganuma, Akira

Publication type:

Article

Overexpression of CLN1, CLN2, or ERG13 increases resistance to adriamycin in Saccharomyces cerevisiae.

Published in:

Journal of Toxicological Sciences, 2011, v. 36, n. 6, p. 855, doi. 10.2131/jts.36.855

By:

Takahashi, Tsutomu;
Nakashima, Shingo;
Masuda, Takuro;
Yoneda, Shigehiro;
Gi-Wook Hwang;
Naganuma, Akira

Publication type:

Article

siRNA-mediated silencing of the gene for heat shock transcription factor 1 causes hypersensitivity to methylmercury in HEK293 cells.

Published in:

Journal of Toxicological Sciences, 2011, v. 36, n. 6, p. 851, doi. 10.2131/jts.36.851

By:

Gi-Wook Hwang;
Ryoke, Katsunori;
Jin-Yong Lee;
Takahashi, Tsutomu;
Naganuma, Akira

Publication type:

Article

Inhibition of F-box protein FBXO6 gene expression by RNA interference enhances cadmium toxicity in HEK293 cells.

Published in:

Journal of Toxicological Sciences, 2011, v. 36, n. 6, p. 847, doi. 10.2131/jts.36.847

By:

Gi-Wook Hwang;
Ke Du;
Takahashi, Tsutomu;
Naganuma, Akira

Publication type:

Article

Gene expression profiling using DNA microarray analysis of the cerebellum of mice treated with methylmercury.

Published in:

Journal of Toxicological Sciences, 2011, v. 36, n. 3, p. 389, doi. 10.2131/jts.36.389

By:

Gi-Wook Hwang;
Jin-Yong Lee;
Katsunori Ryoke;
Fujio Matsuyama;
Jong-Mu Kim;
Tsutomu Takahashi;
Akira Naganuma

Publication type:

Article

siRNA-mediated knockdown of the melanocortin 2 receptor accessory protein 2 (MRAP2) gene confers resistance to methylmercury on HEK293 cells.

Published in:

Journal of Toxicological Sciences, 2010, v. 35, n. 6, p. 947, doi. 10.2131/jts.35.947

By:

Gi-Wook Hwang;
Seong-Eun Oh;
Takahashi, Tsutomu;
Jin-Yong Lee;
Naganuma, Akira

Publication type:

Article

Overexpression of FAP7, MIG3, TMA19, or YLR392c confers resistance to arsenite on Saccharomyces cerevisiae.

Published in:

Journal of Toxicological Sciences, 2010, v. 35, n. 6, p. 945, doi. 10.2131/jts.35.945

By:

Takahashi, Tsutomu;
Yano, Toomi;
JunXuan Zhu;
Gi-Wook Hwang;
Naganuma, Akira

Publication type:

Article

Silencing of the gene for homeobox protein HOXB13 by siRNA confers resistance to methylmercury on HEK293 cells.

Published in:

Journal of Toxicological Sciences, 2010, v. 35, n. 6, p. 941, doi. 10.2131/jts.35.941

By:

Gi-Wook Hwang;
Ryoke, Katsunori;
Takahashi, Tsutomu;
Naganuma, Akira

Publication type:

Article

Rip1 enhances methylmercury toxicity through production of reactive oxygen species (ROS) in budding yeast.

Published in:

Journal of Toxicological Sciences, 2009, v. 34, n. 6, p. 715, doi. 10.2131/jts.34.715

By:

Jin-Yong Lee;
Gi-Wook Hwang;
Naganuma, Akira

Publication type:

Article

Overexpression of Ycg1 or Ydr520c confers resistance to cadmium in Saccharomyces cerevisiae.

Published in:

Journal of Toxicological Sciences, 2009, v. 34, n. 4, p. 441, doi. 10.2131/jts.34.441

By:

Gi-Wook Hwang;
Sasaki, Kanae;
Takahashi, Tsutomu;
Yamamoto, Reiko;
Naganuma, Akira

Publication type:

Article

Overexpression of the novel F-box protein Ymr258c confers resistance to methylmercury in Saccharomyces cerevisiae.

Published in:

Journal of Toxicological Sciences, 2009, v. 34, n. 4, p. 413, doi. 10.2131/jts.34.413

By:

Gi-Wook Hwang;
Wada, Naomi;
Kuge, Shusuke;
Naganuma, Akira

Publication type:

Article

Hydrogen Peroxide Causes Cell Death via Increased Transcription of HOXB13 in Human Lung Epithelial A549 Cells.

Published in:

Toxics, 2020, v. 8, n. 4, p. 78, doi. 10.3390/toxics8040078

By:

Endo, Naoki;
Toyama, Takashi;
Naganuma, Akira;
Saito, Yoshiro;
Hwang, Gi-Wook

Publication type:

Article

Effect of Metallothionein-III on Mercury-Induced Chemokine Gene Expression.

Published in:

Toxics, 2018, v. 6, n. 3, p. 48, doi. 10.3390/toxics6030048

By:

Lee, Jin-Yong;
Tokumoto, Maki;
Hwang, Gi-Wook;
Kim, Min-Seok;
Takahashi, Tsutomu;
Naganuma, Akira;
Yoshida, Minoru;
Satoh, Masahiko

Publication type:

Article

Chemokine CCL4 Induced in Mouse Brain Has a Protective Role against Methylmercury Toxicity.

Published in:

Toxics, 2018, v. 6, n. 3, p. 36, doi. 10.3390/toxics6030036

By:

Takahashi, Tsutomu;
Kim, Min-Seok;
Iwai-Shimada, Miyuki;
Fujimura, Masatake;
Toyama, Takashi;
Naganuma, Akira;
Hwang, Gi-Wook

Publication type:

Article

The Phospholipid:Diacylglycerol Acyltransferase Lro1 Is Responsible for Hepatitis C Virus Core-Induced Lipid Droplet Formation in a Yeast Model System.

Published in:

PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0159324

By:

Iwasa, Shingo;
Sato, Naoko;
Wang, Chao-Wen;
Cheng, Yun-Hsin;
Irokawa, Hayato;
Hwang, Gi-Wook;
Naganuma, Akira;
Kuge, Shusuke

Publication type:

Article

Methylmercury Induces Apoptosis in Mouse C17.2 Neural Stem Cells through the Induction of OSGIN1 Expression by NRF2.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 7, p. 3886, doi. 10.3390/ijms25073886

By:

Yamashita, Naoya;
Uchiyama, Marino;
Yamagata, Ryota;
Hwang, Gi-Wook

Publication type:

Article

The polypeptide antibiotic polymyxin B acts as a pro-inflammatory irritant by preferentially targeting macrophages.

Published in:

Journal of Antibiotics, 2022, v. 75, n. 1, p. 29, doi. 10.1038/s41429-021-00490-7

By:

Kagi, Tomohiro;
Naganuma, Rio;
Inoue, Aya;
Noguchi, Takuya;
Hamano, Shuhei;
Sekiguchi, Yuto;
Hwang, Gi-Wook;
Hirata, Yusuke;
Matsuzawa, Atsushi

Publication type:

Article

Perinatal Exposure to Arsenic in Drinking Water Alters Glutamatergic Neurotransmission in the Striatum of C57BL/6 Mice.

Published in:

Biological Trace Element Research, 2019, v. 187, n. 1, p. 224, doi. 10.1007/s12011-018-1374-2

By:

Sung, Kyunghwa;
Kim, Minjeong;
Kim, Haesoo;
Hwang, Gi-Wook;
Kim, Kisok

Publication type:

Article

Biphasic adverse effect of titanium nanoparticles on testicular function in mice.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-50741-9

By:

Miura, Nobuhiko;
Ohtani, Katsumi;
Hasegawa, Tatsuya;
Yoshioka, Hiroki;
Hwang, Gi-Wook

Publication type:

Article

Identification of F-box proteins that are involved in resistance to methylmercury in Saccharomyces cerevisiae

Published in:

FEBS Letters, 2006, v. 580, n. 30, p. 6813, doi. 10.1016/j.febslet.2006.11.045

By:

Hwang, Gi-Wook;
Ishida, Yosuke;
Naganuma, Akira

Publication type:

Article

Knockdown of TXNIP attenuates methylmercury toxicity in mouse neuronal C17.2 cells.

Published in:

Fundamental Toxicological Sciences, 2025, v. 12, n. 2, p. 29, doi. 10.2131/fts.12.29

By:

Ryoko Fukushima;
Naoya Yamashita;
Soujun Yadoya;
Ryota Yamagata;
Gi-Wook Hwang

Publication type:

Article

siRNA-MEDIATED INHIBITION OF PHOSPHATIDYLINOSITOL GLYCAN CLASS (PIGB) CONFERS RESISTANCE TO METHYLMERCURY IN HEK293 CELLS.

Published in:

Journal of Toxicological Sciences, 2007, v. 32, n. 5, p. 581, doi. 10.2131/jts.32.581

By:

Gi-Wook Hwang;
Hayashi, Tatsuya;
Kita, Kayoko;
Takahashi, Tsutomu;
Kuge, Shusuke;
Naganuma, Akira

Publication type:

Article

DNA MICROARRAY ANALYSIS OF TRANSCRIPTIONAL RESPONSES OF HUMAN NEUROBLASTOMA IMR-32 CELLS TO METHYLMERCURY.

Published in:

Journal of Toxicological Sciences, 2006, v. 31, n. 5, p. 537, doi. 10.2131/jts.31.537

By:

Gi-Wook Hwang;
Naganuma, Akira

Publication type:

Article

Methylmercury toxic mechanism related to protein degradation and chemokine transcription.

Published in:

Environmental Health & Preventive Medicine, 2020, v. 25, n. 1, p. 1, doi. 10.1186/s12199-020-00868-3

By:

Lee, Jin-Yong;
Hwang, Gi-Wook;
Naganuma, Akira;
Satoh, Masahiko

Publication type:

Article

Comprehensive analyses of the cysteine thiol oxidation of PKM2 reveal the effects of multiple oxidation on cellular oxidative stress response.

Published in:

Biochemical Journal, 2021, v. 478, n. 7, p. 1453, doi. 10.1042/BCJ20200897

By:

Hayato Irokawa;
Satoshi Numasaki;
Shin Kato;
Kenta Iwai;
Atsushi Inose-Maruyama;
Takumi Ohdate;
Gi-Wook Hwang;
Takashi Toyama;
Toshihiko Watanabe;
Shusuke Kuge

Publication type:

Article