Works by Ghufran, Mehreen

Results: 15

Structure-Based Development of New and Potent Inhibitors of PIM Kinases: A Computational Study.

Published in:

Journal of the Chemical Society of Pakistan, 2017, v. 39, n. 1, p. 132

By:

Wadood, Abdul;
Khan, Huma;
Ghufran, Mehreen;
Hassan, Hammad;
Shams, Sulaiman;
Khan, Ajmal;
Azam, Syed Sikander;
Uddin, Reaz

Publication type:

Article

In Silico Strategies for Designing of Peptide Inhibitors of Oncogenic K-Ras G12V Mutant: Inhibiting Cancer Growth and Proliferation.

Published in:

Cancers, 2022, v. 14, n. 19, p. 4884, doi. 10.3390/cancers14194884

By:

Ghufran, Mehreen;
Khan, Haider Ali;
Ullah, Mehran;
Ghufran, Sabreen;
Ayaz, Muhammad;
Siddiq, Muhammad;
Hassan, Syed Shams ul;
Bungau, Simona

Publication type:

Article

Synthesis, Enzyme Inhibition, and Molecular Docking Studies of Hydrazones from Dichlorophenylacetic Acids.

Published in:

Journal of the Chinese Chemical Society, 2016, v. 63, n. 12, p. 1015, doi. 10.1002/jccs.201600163

By:

Abid, Obaid‐ur‐Rahman;
Ayaz, Muhammad;
Rehman, Wajid;
Mehdi, Kamran;
Ali, Arif;
Wadood, Abdul;
Rahim, Fazal;
Sultan, Aneesa;
Ghufran, Mehreen;
Mir, Sadullah;
Qureshi, Muhammad Tauseef

Publication type:

Article

Phytochemicals-based β-amyloid cleaving enzyme-1 and MAO-B inhibitors for the treatment of Alzheimer's disease: molecular simulations-based predictions.

Published in:

Journal of Biomolecular Structure & Dynamics, 2024, v. 42, n. 16, p. 8359, doi. 10.1080/07391102.2023.2265494

By:

Mahnashi, Mater H.;
Ayaz, Muhammad;
Ghufran, Mehreen;
Almazni, Ibrahim Abdullah;
Alqahtani, Omaish;
Alyami, Bandar A.;
Alqahtani, Yahya S.;
Khan, Haider Ali;
Sadiq, Abdul;
Waqas, Muhammad

Publication type:

Article

New lead compounds identification against KRas mediated cancers through pharmacophore-based virtual screening and in vitro assays.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 16, p. 8053, doi. 10.1080/07391102.2022.2128878

By:

Ghufran, Mehreen;
Rehman, Ashfaq Ur;
Ayaz, Muhammad;
ul-Haq, Zaheer;
Uddin, Reaz;
Azam, Syed Sikander;
Wadood, Abdul

Publication type:

Article

In-silico evaluations of the isolated phytosterols from polygonum hydropiper L against BACE1 and MAO drug targets.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 20, p. 10230, doi. 10.1080/07391102.2021.1940286

By:

Ayaz, Muhammad;
Wadood, Abdul;
Sadiq, Abdul;
Ullah, Farhat;
Anichkina, Olga;
Ghufran, Mehreen

Publication type:

Article

In-silico design of peptide inhibitors of K-Ras target in cancer disease.

Published in:

Journal of Biomolecular Structure & Dynamics, 2020, v. 38, n. 18, p. 5488, doi. 10.1080/07391102.2019.1704880

By:

Ghufran, Mehreen;
Rehman, Ashfaq Ur;
Shah, Masaud;
Ayaz, Muhammad;
Ng, Ho Leung;
Wadood, Abdul

Publication type:

Article

Synthesis, pharmacological screening and computational analysis of some 2-(1H-Indol-3-yl)-N'-((un)substituted phenylmethylidene) acetohydrazides and 2-(1H-Indol-3-yl)-N'-((un)substituted benzoyl/2- thienylcarbonyl)acetohydrazides.

Published in:

Pakistan Journal of Pharmaceutical Sciences, 2017, v. 30, n. 4, p. 1263

By:

Rubab, Kaniz;
Abbasi, Muhammad Athar;
Rehman, Aziz-ur;
Siddiqui, Sabahat Zahra;
Shah, Syed Adnan Ali;
Ashraf, Muhammad;
Ain, Qurat-ul;
Ahmad, Irshad;
Lodhi, Muhammad Arif;
Ghufran, Mehreen;
Shahid, Muhammad;
Fatima, Hina

Publication type:

Article

Synthesis, in vitro urease inhibitory activity and molecular docking of 3,5‐disubstituted thiadiazine‐2‐thiones.

Published in:

Journal of Heterocyclic Chemistry, 2019, v. 56, n. 11, p. 3073, doi. 10.1002/jhet.3705

By:

Shah, Muhammad Ishaq Ali;
Khan, Rasool;
Arfan, Mohammad;
Wadood, Abdul;
Ghufran, Mehreen

Publication type:

Article

Theoretical and Experimental in vitro Antifungal and Antitumor Activities of Organotin(IV) Derivatives of 3-(4-nitrophenyl)-2-methylacrylic acid.

Published in:

Pharmaceutical Chemistry Journal, 2019, v. 53, n. 8, p. 689, doi. 10.1007/s11094-019-02064-2

By:

Muhammad, Niaz;
Shah, Naseer Ali;
Ali, Saqib;
Elahi, Sadaf Noor;
Rehman, Wajid;
Shujah, Shaukat;
Khan, Muhammad Rashid;
Wadood, Abdul;
Ghufran, Mehreen;
Rashid, Umer

Publication type:

Article

In-Silico Lead Druggable Compounds Identification against SARS COVID-19 Main Protease Target from In-House, Chembridge and Zinc Databases by Structure-Based Virtual Screening, Molecular Docking and Molecular Dynamics Simulations.

Published in:

Bioengineering (Basel), 2023, v. 10, n. 1, p. 100, doi. 10.3390/bioengineering10010100

By:

Ghufran, Mehreen;
Ullah, Mehran;
Khan, Haider Ali;
Ghufran, Sabreen;
Ayaz, Muhammad;
Siddiq, Muhammad;
Abbas, Syed Qamar;
Hassan, Syed Shams ul;
Bungau, Simona

Publication type:

Article

Antimicrobial efficiency of diorganotin(IV) bis-[3-(4-chlorophenyl)-2-methylacrylate].

Published in:

Journal of Coordination Chemistry, 2018, v. 71, n. 20, p. 3315, doi. 10.1080/00958972.2018.1513131

By:

Muhammad, Niaz;
Ali Shah, Naseer;
Ali, Saqib;
Wadood, Abdul;
Ghufran, Mehreen;
Rashid Khan, Muhammad;
Siddiq, Pakiza;
Shujah, Shaukat;
Meetsma, Auke

Publication type:

Article

HPLC-DAD phenolics analysis, α-glucosidase, α-amylase inhibitory, molecular docking and nutritional profiles of Persicaria hydropiper L.

Published in:

BMC Complementary Medicine & Therapies, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12906-022-03510-7

By:

Mahnashi, Mater H.;
Alqahtani, Yahya S.;
Alyami, Bandar A.;
Alqarni, Ali O.;
Alqahl, Sultan A.;
Ullah, Farhat;
Sadiq, Abdul;
Zeb, Alam;
Ghufran, Mehreen;
Kuraev, Alexey;
Nawaz, Asif;
Ayaz, Muhammad

Publication type:

Article

S-Alkylated/aralkylated 2-(1H-indol-3-yl-methyl)-1,3,4- oxadiazole-5-thiol derivatives. 2. Anti-bacterial, enzymeinhibitory and hemolytic activities.

Published in:

Tropical Journal of Pharmaceutical Research, 2016, v. 15, n. 7, p. 1525, doi. 10.4314/tjpr.v15i7.24

By:

Rubab, Kaniz;
Abbasi, Muhammad A.;
Aziz-ur-Rehman;
Siddiqui, Sabahat Z.;
Ashraf, Muhammad;
Shaukat, Ayesha;
Ahmad, Irshad;
Hassan, Sidra;
Lodhi, Muhammad A.;
Ghufran, Mehreen;
Shahid, Muhammad;
Fatima, Hina

Publication type:

Article

In silico identification of promiscuous scaffolds as potential inhibitors of 1-deoxy- d -xylulose 5-phosphate reductoisomerase for treatment of Falciparum malaria.

Published in:

Pharmaceutical Biology, 2017, v. 55, n. 1, p. 19, doi. 10.1080/13880209.2016.1225778

By:

Wadood, Abdul;
Ghufran, Mehreen;
Hassan, Syed Fahad;
Khan, Huma;
Azam, Syed Sikandar;
Rashid, Umer

Publication type:

Article