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Is systems pharmacology ready to impact upon therapy development? A study on the cholesterol biosynthesis pathway.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Construction of a large scale integrated map of macrophage pathogen recognition and effector systems.
- Published in:
- BMC Systems Biology, 2010, v. 4, p. 63, doi. 10.1186/1752-0509-4-63
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- Publication type:
- Article
The mEPN scheme: an intuitive and flexible graphical system for rendering biological pathways.
- Published in:
- BMC Systems Biology, 2010, v. 4, p. 65, doi. 10.1186/1752-0509-4-65
- By:
- Publication type:
- Article
A logic-based diagram of signalling pathways central to macrophage activation.
- Published in:
- BMC Systems Biology, 2008, v. 2, p. 1, doi. 10.1186/1752-0509-2-36
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- Publication type:
- Article
Cytomegalovirus-Specific IL-10-Producing CD4<sup>+</sup> T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence.
- Published in:
- PLoS Pathogens, 2016, v. 12, n. 12, p. 1, doi. 10.1371/journal.ppat.1006050
- By:
- Publication type:
- Article
Gene filtering strategies for machine learning guided biomarker discovery using neonatal sepsis RNA-seq data.
- Published in:
- Frontiers in Genetics, 2023, v. 14, p. 1, doi. 10.3389/fgene.2023.1158352
- By:
- Publication type:
- Article
Identification of a human neonatal immune-metabolic network associated with bacterial infection.
- Published in:
- Nature Communications, 2014, v. 5, n. 8, p. 4649, doi. 10.1038/ncomms5649
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- Publication type:
- Article
HMOX1 genetic polymorphisms and outcomes in infectious disease: A systematic review.
- Published in:
- PLoS ONE, 2022, v. 17, n. 5, p. 1, doi. 10.1371/journal.pone.0267399
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- Publication type:
- Article
Sex-Differential Non-Vaccine-Specific Immunological Effects of Diphtheria-Tetanus-Pertussis and Measles Vaccination.
- Published in:
- Clinical Infectious Diseases, 2016, v. 63, n. 9, p. 1213, doi. 10.1093/cid/ciw492
- By:
- Publication type:
- Article
Fluorescence Lifetime Imaging of Quantum Dot Labeled DNA Microarrays.
- Published in:
- International Journal of Molecular Sciences, 2009, v. 10, n. 4, p. 1930, doi. 10.3390/ijms10041930
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- Publication type:
- Article
Genome-wide expression profiling of in vivo-derived bloodstream parasite stages and dynamic analysis of mRNA alterations during synchronous differentiation in Trypanosoma brucei.
- Published in:
- BMC Genomics, 2009, v. 10, p. 427, doi. 10.1186/1471-2164-10-427
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- Publication type:
- Article
Combined genome-wide expression profiling and targeted RNA interference in primary mouse macrophages reveals perturbation of transcriptional networks associated with interferon signalling.
- Published in:
- BMC Genomics, 2009, v. 10, p. 372, doi. 10.1186/1471-2164-10-372
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- Publication type:
- Article
GPX-Macrophage Expression Atlas: A database for expression profiles of macrophages challenged with a variety of pro-inflammatory, anti-inflammatory, benign and pathogen insults.
- Published in:
- BMC Genomics, 2005, v. 6, p. 178, doi. 10.1186/1471-2164-6-178
- By:
- Publication type:
- Article
PEDRo: A database for storing, searching and disseminating experimental proteomics data.
- Published in:
- BMC Genomics, 2004, v. 5, p. 68, doi. 10.1186/1471-2164-5-68
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- Publication type:
- Article
A Temporal Gate for Viral Enhancers to Co-opt Toll-Like-Receptor Transcriptional Activation Pathways upon Acute Infection.
- Published in:
- PLoS Pathogens, 2015, v. 11, n. 4, p. 1, doi. 10.1371/journal.ppat.1004737
- By:
- Publication type:
- Article
CD200 Receptor Restriction of Myeloid Cell Responses Antagonizes Antiviral Immunity and Facilitates Cytomegalovirus Persistence within Mucosal Tissue.
- Published in:
- PLoS Pathogens, 2015, v. 11, n. 2, p. 1, doi. 10.1371/journal.ppat.1004641
- By:
- Publication type:
- Article
Viral Enhancer Mimicry of Host Innate-Immune Promoters.
- Published in:
- 2014
- By:
- Publication type:
- Opinion
A Systematic Analysis of Host Factors Reveals a Med23-Interferon-λ Regulatory Axis against Herpes Simplex Virus Type 1 Replication.
- Published in:
- PLoS Pathogens, 2013, v. 9, n. 8, p. 1, doi. 10.1371/journal.ppat.1003514
- By:
- Publication type:
- Article
Ablation of the Regulatory IE1 Protein of Murine Cytomegalovirus Alters In Vivo Pro-inflammatory TNF-alpha Production during Acute Infection.
- Published in:
- PLoS Pathogens, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.ppat.1002901
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- Publication type:
- Article
Viral Mediated Redirection of NEMO/IKKγ to Autophagosomes Curtails the Inflammatory Cascade.
- Published in:
- PLoS Pathogens, 2012, v. 8, n. 2, p. 1, doi. 10.1371/journal.ppat.1002517
- By:
- Publication type:
- Article
HMOX1 STR polymorphism and malaria: an analysis of a large clinical dataset
- Published in:
- Malaria Journal, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12936-022-04352-x
- By:
- Publication type:
- Article
MULTI-FACTORIAL ANALYSIS OF CLASS PREDICTION ERROR:: ESTIMATING OPTIMAL NUMBER OF BIOMARKERS FOR VARIOUS CLASSIFICATION RULES.
- Published in:
- Journal of Bioinformatics & Computational Biology, 2010, v. 8, n. 6, p. 945, doi. 10.1142/S0219720010005063
- By:
- Publication type:
- Article
Time-lapse ultrashort pulse microscopy of infection in three-dimensional versus two-dimensional culture environments reveals enhanced extra-chromosomal virus replication compartment formation.
- Published in:
- Journal of Biomedical Optics, 2013, v. 18, n. 3, p. 1, doi. 10.1117/1.JBO.18.3.031111
- By:
- Publication type:
- Article
Assessment of transcriptomal analysis of varicella-zoster-virus gene expression in patients with and without post-herpetic neuralgia.
- Published in:
- Virus Genes, 2010, v. 41, n. 2, p. 192, doi. 10.1007/s11262-010-0515-2
- By:
- Publication type:
- Article
Genome-wide reduction in transcriptomal profiles of varicella-zoster virus vaccine strains compared with Parental Oka strain using long oligonucleotide microarrays.
- Published in:
- Virus Genes, 2009, v. 38, n. 1, p. 19, doi. 10.1007/s11262-008-0304-3
- By:
- Publication type:
- Article
In vivo transduction of photoreceptors or ciliary body by intravitreal injection of pseudotyped adenoviral vectors
- Published in:
- Molecular Therapy, 2003, v. 7, n. 1, p. 27, doi. 10.1016/S1525-0016(02)00030-8
- By:
- Publication type:
- Article
The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08332-9
- By:
- Publication type:
- Article
Low levels of small HDL particles predict but do not influence risk of sepsis.
- Published in:
- Critical Care, 2023, v. 27, n. 1, p. 1, doi. 10.1186/s13054-023-04589-1
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- Publication type:
- Article
Erratum: The Systems Biology Graphical Notation.
- Published in:
- 2009
- By:
- Publication type:
- Correction notice
The Systems Biology Graphical Notation.
- Published in:
- Nature Biotechnology, 2009, v. 27, n. 8, p. 735, doi. 10.1038/nbt.1558
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- Publication type:
- Article
Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project.
- Published in:
- Nature Biotechnology, 2008, v. 26, n. 8, p. 889, doi. 10.1038/nbt.1411
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- Publication type:
- Article
An optimised dosing regimen versus a standard dosing regimen of vancomycin for the treatment of late onset sepsis due to Gram-positive microorganisms in neonates and infants aged less than 90 days (NeoVanc): study protocol for a randomised controlled trial.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Genomics and Pathway Biology -- a new post-genomics M.Sc. programme from Edinburgh University.
- Published in:
- 2005
- By:
- Publication type:
- Conference Paper
Annexation of the interchromosomal space during viral infection.
- Published in:
- Nature Cell Biology, 2000, v. 2, n. 9, p. 661, doi. 10.1038/35023615
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- Publication type:
- Article
A Loss of Function Analysis of Host Factors Influencing <i>Vaccinia virus</i> Replication by RNA Interference.
- Published in:
- PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0098431
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- Publication type:
- Article
Fast DNA and protein microarray tests for the diagnosis of hepatitis C virus infection on a single platform.
- Published in:
- Analytical & Bioanalytical Chemistry, 2012, v. 401, n. 8, p. 2549, doi. 10.1007/s00216-011-5332-5
- By:
- Publication type:
- Article
CD1d-dependent rewiring of lipid metabolism in macrophages regulates innate immune responses.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34532-x
- By:
- Publication type:
- Article
CD1d-dependent rewiring of lipid metabolism in macrophages regulates innate immune responses.
- Published in:
- Nature Communications, 2022, v. 13, p. 1, doi. 10.1038/s41467-022-34532-x
- By:
- Publication type:
- Article
Purine metabolism controls innate lymphoid cell function and protects against intestinal injury.
- Published in:
- Immunology & Cell Biology, 2018, v. 96, n. 10, p. 1049, doi. 10.1111/imcb.12167
- By:
- Publication type:
- Article
Human cytomegalovirus UL7, a homologue of the SLAM-family receptor CD229, impairs cytokine production.
- Published in:
- Immunology & Cell Biology, 2011, v. 89, n. 7, p. 753, doi. 10.1038/icb.2011.55
- By:
- Publication type:
- Article
Metabolic Regulators Nampt and Sirt6 Serially Participate in the Macrophage Interferon Antiviral Cascade.
- Published in:
- Frontiers in Microbiology, 2019, p. N.PAG, doi. 10.3389/fmicb.2019.00355
- By:
- Publication type:
- Article
Genomic Programming of Human Neonatal Dendritic Cells in Congenital Systemic and In Vitro Cytomegalovirus Infection Reveal Plastic and Robust Immune Pathway Biology Responses.
- Published in:
- Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01146
- By:
- Publication type:
- Article
Evolutionary Origin of the Interferon-Immune Metabolic Axis: The Sterol-Vitamin D Link.
- Published in:
- Frontiers in Immunology, 2017, v. 8, p. 1, doi. 10.3389/fimmu.2017.00062
- By:
- Publication type:
- Article
Interferon Control of the Sterol Metabolic Network: Bidirectional Molecular Circuitry-Mediating Host Protection.
- Published in:
- Frontiers in Immunology, 2016, v. 7, p. 1, doi. 10.3389/fimmu.2016.00634
- By:
- Publication type:
- Article
Conventional and unconventional T-cell responses contribute to the prediction of clinical outcome and causative bacterial pathogen in sepsis patients.
- Published in:
- Clinical & Experimental Immunology, 2024, v. 216, n. 3, p. 293, doi. 10.1093/cei/uxae019
- By:
- Publication type:
- Article
Deciphering the modulation of gene expression by type I and II interferons combining 4sU-tagging, translational arrest and in silico promoter analysis.
- Published in:
- Nucleic Acids Research, 2013, v. 41, n. 17, p. 8107, doi. 10.1093/nar/gkt589
- By:
- Publication type:
- Article
Nanoinformatics: developing new computing applications for nanomedicine.
- Published in:
- Computing, 2012, v. 94, n. 6, p. 521, doi. 10.1007/s00607-012-0191-2
- By:
- Publication type:
- Article
Parallel classification and feature selection in microarray data using SPRINT.
- Published in:
- Concurrency & Computation: Practice & Experience, 2014, v. 26, n. 4, p. 854, doi. 10.1002/cpe.2928
- By:
- Publication type:
- Article
Optimization of a parallel permutation testing function for the SPRINT R package.
- Published in:
- Concurrency & Computation: Practice & Experience, 2011, v. 23, n. 17, p. 2258, doi. 10.1002/cpe.1787
- By:
- Publication type:
- Article
Principles of homeostasis in governing virus activation and latency.
- Published in:
- Immunologic Research, 2000, v. 21, n. 2/3, p. 219, doi. 10.1385/IR:21:2-3:219
- By:
- Publication type:
- Article