Works by Gharahkhani, Puya

Results: 49

Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology.

Published in:

Genetic Epidemiology, 2015, v. 39, n. 3, p. 207, doi. 10.1002/gepi.21886

By:

Springelkamp, Henriët;
Mishra, Aniket;
Hysi, Pirro G.;
Gharahkhani, Puya;
Höhn, René;
Khor, Chiea ‐ Chuen;
Cooke Bailey, Jessica N.;
Luo, Xiaoyan;
Ramdas, Wishal D.;
Vithana, Eranga;
Koh, Victor;
Yazar, Seyhan;
Xu, Liang;
Forward, Hannah;
Kearns, Lisa S.;
Amin, Najaf;
Iglesias, Adriana I.;
Sim, Kar ‐ Seng;
Leeuwen, Elisabeth M.;
Demirkan, Ayse

Publication type:

Article

Haplotype reference consortium panel: Practical implications of imputations with large reference panels.

Published in:

Human Mutation, 2017, v. 38, n. 8, p. 1025, doi. 10.1002/humu.23247

By:

Iglesias, Adriana I.;
der Lee, Sven J.;
Bonnemaijer, Pieter W.M.;
Höhn, René;
Nag, Abhishek;
Gharahkhani, Puya;
Khawaja, Anthony P.;
Broer, Linda;
Foster, Paul J.;
Hammond, Christopher J.;
Hysi, Pirro G.;
Leeuwen, Elisabeth M.;
MacGregor, Stuart;
Mackey, David A.;
Mazur, Johanna;
Nickels, Stefan;
Uitterlinden, André G.;
Klaver, Caroline C.W.;
Amin, Najaf;
Duijn, Cornelia M.

Publication type:

Article

Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-34713-z

By:

Ong, Jue-Sheng;
Hwang, Daniel Liang-Dar;
Zhong, Victor W.;
An, Jiyuan;
Gharahkhani, Puya;
Breslin, Paul A. S.;
Wright, Margaret J.;
Lawlor, Deborah A.;
Whitfield, John;
MacGregor, Stuart;
Martin, Nicholas G.;
Cornelis, Marilyn C.

Publication type:

Article

Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma.

Published in:

Nature Genetics, 2014, v. 46, n. 10, p. 1120, doi. 10.1038/ng.3079

By:

Gharahkhani, Puya;
MacGregor, Stuart;
Hauser, Michael A;
Viswanathan, Ananth C;
Foster, Paul J;
McGuffin, Peter;
Topouzis, Fotis;
Graham, Stuart L;
Casson, Robert J;
Chehade, Mark;
White, Andrew J;
Healey, Paul R;
Wang, Jie Jin;
Mitchell, Paul;
Klebe, Sonja;
Goldberg, Ivan;
Radford-Smith, Graham;
Burdon, Kathryn P;
Mackey, David A;
Craig, Jamie E

Publication type:

Article

Multi-trait genome-wide association study identifies new loci associated with optic disc parameters.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0634-9

By:

Bonnemaijer, Pieter W. M.;
Leeuwen, Elisabeth M. van;
Iglesias, Adriana I.;
Gharahkhani, Puya;
Vitart, Veronique;
Khawaja, Anthony P.;
Simcoe, Mark;
Höhn, René;
Cree, Angela J.;
Igo, Rob P.;
International Glaucoma Genetics Consortium;
Burdon, Kathryn P.;
Craig, Jamie E.;
Hewitt, Alex W.;
Jonas, Jost;
Khor, Chiea-Cheun;
Pasutto, Francesca;
Mackey, David A.;
Mitchell, Paul;
Mishra, Aniket

Publication type:

Article

Speech and language biomarkers for Parkinson's disease prediction, early diagnosis and progression.

Published in:

NPJ Parkinson's Disease, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41531-025-00913-4

By:

Cao, Fangyuan;
Vogel, Adam P.;
Gharahkhani, Puya;
Renteria, Miguel E.

Publication type:

Article

Germline variation in the insulin-like growth factor pathway and risk of Barrett's esophagus and esophageal adenocarcinoma.

Published in:

Carcinogenesis, 2021, v. 42, n. 3, p. 369, doi. 10.1093/carcin/bgaa132

By:

Dighe, Shruti G;
Chen, Jianhong;
Yan, Li;
He, Qianchuan;
Gharahkhani, Puya;
Onstad, Lynn;
Levine, David M;
Palles, Claire;
Ye, Weimin;
Gammon, Marilie D;
Iyer, Prasad G;
Anderson, Lesley A;
Liu, Geoffrey;
Wu, Anna H;
Dai, James Y;
Chow, Wong-Ho;
Risch, Harvey A;
Lagergren, Jesper;
Shaheen, Nicholas J;
Bernstein, Leslie

Publication type:

Article

A Non-Synonymous Mutation in the Canine Pkd1 Gene Is Associated with Autosomal Dominant Polycystic Kidney Disease in Bull Terriers.

Published in:

PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022455

By:

Gharahkhani, Puya;
O'Leary, Caroline A.;
Kyaw-Tanner, Myat;
Sturm, Richard A.;
Duffy, David L.

Publication type:

Article

Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images.

Published in:

PLoS Genetics, 2021, v. 17, n. 5, p. 1, doi. 10.1371/journal.pgen.1009497

By:

Currant, Hannah;
Hysi, Pirro;
Fitzgerald, Tomas W.;
Gharahkhani, Puya;
Bonnemaijer, Pieter W. M.;
Senabouth, Anne;
Hewitt, Alex W.;
Atan, Denize;
Aung, Tin;
Charng, Jason;
Choquet, Hélène;
Craig, Jamie;
Khaw, Peng T.;
Klaver, Caroline C. W.;
Kubo, Michiaki;
Ong, Jue-Sheng;
Pasquale, Louis R.;
Reisman, Charles A.;
Daniszewski, Maciej;
Powell, Joseph E.

Publication type:

Article

Genetic Similarity Clustering Using the UK Biobank as a Reference Dataset.

Published in:

Twin Research & Human Genetics, 2025, v. 28, n. 2, p. 119, doi. 10.1017/thg.2025.15

By:

Le, Ngoc-Quynh;
Gharahkhani, Puya;
MacGregor, Stuart

Publication type:

Article

Sweet Taste Perception is Associated with Body Mass Index at the Phenotypic and Genotypic Level.

Published in:

2016

By:

Hwang, Liang-Dar;
Cuellar-Partida, Gabriel;
Ong, Jue-Sheng;
Breslin, Paul A. S.;
Reed, Danielle R.;
MacGregor, Stuart;
Gharahkhani, Puya;
Martin, Nicholas G.;
Rentería, Miguel E.;
Rentería, Miguel E

Publication type:

journal article

Assessing the genetic relationship between gastro-esophageal reflux disease and risk of COVID-19 infection.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 3, p. 471, doi. 10.1093/hmg/ddab253

By:

Ong, Jue-Sheng;
Gharahkhani, Puya;
Vaughan, Thomas L;
Whiteman, David;
Kendall, Bradley J;
MacGregor, Stuart

Publication type:

Article

Genome-wide association analysis of 95 549 individuals identifies novel loci and genes influencing optic disc morphology.

Published in:

Human Molecular Genetics, 2019, v. 28, n. 21, p. 3680, doi. 10.1093/hmg/ddz193

By:

Han, Xikun;
Qassim, Ayub;
An, Jiyuan;
Marshall, Henry;
Zhou, Tiger;
Ong, Jue-Sheng;
Hassall, Mark M;
Hysi, Pirro G;
Foster, Paul J;
Khaw, Peng T;
Mackey, David A;
Gharahkhani, Puya;
Khawaja, Anthony P;
Hewitt, Alex W;
Craig, Jamie E;
MacGregor, Stuart

Publication type:

Article

Combined analysis of keratinocyte cancers identifies novel genome-wide loci.

Published in:

Human Molecular Genetics, 2019, v. 28, n. 18, p. 3148, doi. 10.1093/hmg/ddz121

By:

Liyanage, Upekha E;
Law, Matthew H;
Han, Xikun;
An, Jiyuan;
Ong, Jue-Sheng;
Gharahkhani, Puya;
Gordon, Scott;
Neale, Rachel E;
Olsen, Catherine M;
Team, 23andMe Research;
MacGregor, Stuart;
Whiteman, David C

Publication type:

Article

Vitamin D and overall cancer risk and cancer mortality: a Mendelian randomization study.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 24, p. 4315, doi. 10.1093/hmg/ddy307

By:

Ong, Jue-Sheng;
Gharahkhani, Puya;
An, Jiyuan;
Law, Matthew H;
Whiteman, David C;
Neale, Rachel E;
MacGregor, Stuart

Publication type:

Article

New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 2, p. 438, doi. 10.1093/hmg/ddw399

By:

Springelkamp, Henriët;
Iglesias, Adriana I.;
Mishra, Aniket;
Höhn, René;
Wojciechowski, Robert;
Khawaja, Anthony P.;
Nag, Abhishek;
Ya Xing Wang;
Jie Jin Wang;
Cuellar-Partida, Gabriel;
Gibson, Jane;
Cooke Bailey, Jessica N.;
Vithana, Eranga N.;
Gharahkhani, Puya;
Boutin, Thibaud;
Ramdas, Wishal D.;
Zeller, Tanja;
Luben, Robert N.;
Yonova-Doing, Ekaterina;
Viswanathan, Ananth C.

Publication type:

Article

Chronic gastroesophageal reflux disease shares genetic background with esophageal adenocarcinoma and Barrett's esophagus.

Published in:

Human Molecular Genetics, 2016, v. 25, n. 4, p. 828, doi. 10.1093/hmg/ddv512

By:

Gharahkhani, Puya;
Tung, Joyce;
Hinds, David;
Mishra, Aniket;
Vaughan, Thomas L.;
Whiteman, David C.;
MacGregor, Stuart

Publication type:

Article

A common variant near TGFBR3 is associated with primary open angle glaucoma.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 13, p. 3880, doi. 10.1093/hmg/ddv128

By:

Zheng Li;
Allingham, R. Rand;
Masakazu Nakano;
Liyun Jia;
Yuhong Chen;
Yoko Ikeda;
Mani, Baskaran;
Li-Jia Chen;
Changwon Kee;
Garway-Heath, David F.;
Sripriya, Sarangapani;
Nobuo Fuse;
Abu-Amero, Khaled K.;
Chukai Huang;
Namburi, Prasanthi;
Burdon, Kathryn;
Perera, Shamira A.;
Gharahkhani, Puya;
Ying Lin;
Morio Ueno

Publication type:

Article

ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 9, p. 2689, doi. 10.1093/hmg/ddv027

By:

Springelkamp, Henriët;
Iglesias, Adriana I.;
Cuellar-Partida, Gabriel;
Amin, Najaf;
Burdon, Kathryn P.;
van Leeuwen, Elisabeth M.;
Gharahkhani, Puya;
Mishra, Aniket;
van der Lee, Sven J.;
Hewitt, Alex W.;
Rivadeneira, Fernando;
Viswanathan, Ananth C.;
Wolfs, Roger C. W.;
Martin, Nicholas G.;
Ramdas, Wishal D.;
van Koolwijk, Leonieke M.;
Pennell, Craig E.;
Vingerling, Johannes R.;
Mountain, Jenny E.;
Uitterlinden, André G.

Publication type:

Article

A multi-phenotype analysis reveals 19 susceptibility loci for basal cell carcinoma and 15 for squamous cell carcinoma.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-35345-8

By:

Seviiri, Mathias;
Law, Matthew H.;
Ong, Jue-Sheng;
Gharahkhani, Puya;
Fontanillas, Pierre;
The 23andMe Research Team;
Aslibekyan, Stella;
Auton, Adam;
Babalola, Elizabeth;
Bell, Robert K.;
Bielenberg, Jessica;
Bryc, Katarzyna;
Bullis, Emily;
Coker, Daniella;
Partida, Gabriel Cuellar;
Dhamija, Devika;
Das, Sayantan;
Elson, Sarah L.;
Filshtein, Teresa;
Fletez-Brant, Kipper

Publication type:

Article

Genetic evidence that the causal association of educational attainment with reduced risk of Alzheimer's disease is driven by intelligence.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.061144

By:

Thorp, Jackson G;
Mitchell, Brittany L;
Gerring, Zachary F;
Ong, Jue‐Sheng;
Gharahkhani, Puya;
Derks, Eske M;
Lupton, Michelle K

Publication type:

Article

Polyunsaturated fatty acids and risk of melanoma: A Mendelian randomisation analysis.

Published in:

International Journal of Cancer, 2018, v. 143, n. 3, p. 508, doi. 10.1002/ijc.31334

By:

Liyanage, Upekha E.;
Law, Matthew H.;
Ong, Jue Sheng;
Cust, Anne E.;
Mann, Graham J.;
Ward, Sarah V.;
Melanoma Meta‐Analysis Consortium;
Gharahkhani, Puya;
Iles, Mark M.;
MacGregor, Stuart

Publication type:

Article

Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-07819-1

By:

Iglesias, Adriana I.;
Mishra, Aniket;
Vitart, Veronique;
Bykhovskaya, Yelena;
Höhn, René;
Springelkamp, Henriët;
Cuellar-Partida, Gabriel;
Gharahkhani, Puya;
Bailey, Jessica N. Cooke;
Willoughby, Colin E.;
Li, Xiaohui;
Yazar, Seyhan;
Nag, Abhishek;
Khawaja, Anthony P.;
Polašek, Ozren;
Siscovick, David;
Mitchell, Paul;
Tham, Yih Chung;
Haines, Jonathan L.;
Kearns, Lisa S.

Publication type:

Article

Atopic dermatitis in West Highland white terriers is associated with a 1.3-Mb region on CFA 17.

Published in:

Immunogenetics, 2012, v. 64, n. 3, p. 209, doi. 10.1007/s00251-011-0577-x

By:

Roque, Joana;
O'Leary, Caroline;
Duffy, David;
Kyaw-Tanner, Myat;
Gharahkhani, Puya;
Vogelnest, Linda;
Mason, Kenneth;
Shipstone, Michael;
Latter, Melanie

Publication type:

Article

The effects of eight serum lipid biomarkers on age-related macular degeneration risk: a Mendelian randomization study.

Published in:

2021

By:

Han, Xikun;
Ong, Jue-Sheng;
Hewitt, Alex W;
Gharahkhani, Puya;
MacGregor, Stuart

Publication type:

journal article

Association between coffee consumption and overall risk of being diagnosed with or dying from cancer among >300 000 UK Biobank participants in a large-scale Mendelian randomization study.

Published in:

2019

By:

Ong, Jue-Sheng;
Law, Matthew H;
An, Jiyuan;
Han, Xikun;
Gharahkhani, Puya;
Whiteman, David C;
Neale, Rachel E;
MacGregor, Stuart

Publication type:

journal article

Assessment of moderate coffee consumption and risk of epithelial ovarian cancer: a Mendelian randomization study.

Published in:

2018

By:

Ong, Jue-Sheng;
Hwang, Liang-Dar;
Cuellar-Partida, Gabriel;
Martin, Nicholas G;
Chenevix-Trench, Georgia;
Quinn, Michael C J;
Cornelis, Marilyn C;
Gharahkhani, Puya;
Webb, Penelope M;
MacGregor, Stuart;
Ovarian Cancer Association Consortium

Publication type:

journal article

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20851-4

By:

Gharahkhani, Puya;
Jorgenson, Eric;
Hysi, Pirro;
Khawaja, Anthony P.;
Pendergrass, Sarah;
Han, Xikun;
Ong, Jue Sheng;
Hewitt, Alex W.;
Segrè, Ayellet V.;
Rouhana, John M.;
Hamel, Andrew R.;
Igo, Robert P.;
Choquet, Helene;
Qassim, Ayub;
Josyula, Navya S.;
Cooke Bailey, Jessica N.;
Bonnemaijer, Pieter W. M.;
Iglesias, Adriana;
Siggs, Owen M.;
Young, Terri L.

Publication type:

Article

Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16483-3

By:

Zhang, Yan Dora;
Hurson, Amber N.;
Zhang, Haoyu;
Choudhury, Parichoy Pal;
Easton, Douglas F.;
Milne, Roger L.;
Simard, Jacques;
Hall, Per;
Michailidou, Kyriaki;
Dennis, Joe;
Schmidt, Marjanka K.;
Chang-Claude, Jenny;
Gharahkhani, Puya;
Whiteman, David;
Campbell, Peter T.;
Hoffmeister, Michael;
Jenkins, Mark;
Peters, Ulrike;
Hsu, Li;
Gruber, Stephen B.

Publication type:

Article

Correction: Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images.

Published in:

PLoS Genetics, 2021, v. 17, n. 10, p. 1, doi. 10.1371/journal.pgen.1009858

By:

Currant, Hannah;
Hysi, Pirro;
Fitzgerald, Tomas W.;
Gharahkhani, Puya;
Bonnemaijer, Pieter W. M.;
Senabouth, Anne;
Hewitt, Alex W.;
Atan, Denize;
Aung, Tin;
Charng, Jason;
Choquet, Hélène;
Craig, Jamie;
Khaw, Peng T.;
Klaver, Caroline C. W.;
Kubo, Michiaki;
Ong, Jue-Sheng;
Pasquale, Louis R.;
Reisman, Charles A.;
Daniszewski, Maciej;
Powell, Joseph E.

Publication type:

Article

Predictive Power of Polygenic Risk Scores for Intraocular Pressure or Vertical Cup-Disc Ratio.

Published in:

JAMA Ophthalmology, 2025, v. 143, n. 1, p. 15, doi. 10.1001/jamaophthalmol.2024.4856

By:

He, Weixiong;
Lee, Samantha Sze-Yee;
Diaz Torres, Santiago;
Han, Xikun;
Gharahkhani, Puya;
Hunter, Michael;
Balartnasingam, Chandrakumar;
Craig, Jamie E.;
Hewitt, Alex W.;
Mackey, David A.;
MacGregor, Stuart

Publication type:

Article

Association of Novel Loci With Keratoconus Susceptibility in a Multitrait Genome-Wide Association Study of the UK Biobank Database and Canadian Longitudinal Study on Aging.

Published in:

2022

By:

He, Weixiong;
Han, Xikun;
Ong, Jue-Sheng;
Hewitt, Alex W.;
Mackey, David A.;
Gharahkhani, Puya;
MacGregor, Stuart;
International Glaucoma Genetics Consortium

Publication type:

journal article

Association of Monogenic and Polygenic Risk With the Prevalence of Open-Angle Glaucoma.

Published in:

2021

By:

Siggs, Owen M.;
Han, Xikun;
Qassim, Ayub;
Souzeau, Emmanuelle;
Kuruvilla, Shilpa;
Marshall, Henry N.;
Mullany, Sean;
Mackey, David A.;
Hewitt, Alex W.;
Gharahkhani, Puya;
MacGregor, Stuart;
Craig, Jamie E.

Publication type:

journal article

Association of Myopia and Intraocular Pressure With Retinal Detachment in European Descent Participants of the UK Biobank Cohort: A Mendelian Randomization Study.

Published in:

2020

By:

Han, Xikun;
Ong, Jue-Sheng;
An, Jiyuan;
Craig, Jamie E.;
Gharahkhani, Puya;
Hewitt, Alex W.;
MacGregor, Stuart

Publication type:

journal article

Myocilin Gene Gln368Ter Variant Penetrance and Association With Glaucoma in Population-Based and Registry-Based Studies.

Published in:

2019

By:

Han, Xikun;
Souzeau, Emmanuelle;
Ong, Jue-Sheng;
An, Jiyuan;
Siggs, Owen M.;
Burdon, Kathryn P.;
Best, Stephen;
Goldberg, Ivan;
Healey, Paul R.;
Graham, Stuart L.;
Ruddle, Jonathan B.;
Mills, Richard A.;
Landers, John;
Galanopoulos, Anna;
White, Andrew J.R.;
Casson, Robert;
Mackey, David A.;
Hewitt, Alex W.;
Gharahkhani, Puya;
Craig, Jamie E.

Publication type:

journal article

Developing and validating a comprehensive polygenic risk score to enhance keratoconus risk prediction.

Published in:

Human Molecular Genetics, 2025, v. 34, n. 2, p. 140, doi. 10.1093/hmg/ddae157

By:

He, Weixiong;
Võsa, Urmo;
Palumaa, Teele;
Ong, Jue-Sheng;
Torres, Santiago Diaz;
Hewitt, Alex W;
Mackey, David A;
Gharahkhani, Puya;
Esko, Tõnu;
MacGregor, Stuart

Publication type:

Article

Uncovering genetic loci and biological pathways associated with age-related cataracts through GWAS meta-analysis.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53212-6

By:

Diaz-Torres, Santiago;
Lee, Samantha Sze-Yee;
García-Marín, Luis M.;
Campos, Adrian I.;
Lingham, Garreth;
Ong, Jue-Sheng;
Mackey, David A.;
Burdon, Kathryn P.;
Hunter, Michael;
Dong, Xianjun;
MacGregor, Stuart;
Gharahkhani, Puya;
Rentería, Miguel E.

Publication type:

Article

Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma.

Published in:

PLoS Genetics, 2018, v. 14, n. 1, p. 1, doi. 10.1371/journal.pgen.1007145

By:

King, Rebecca;
Struebing, Felix L.;
Li, Ying;
Wang, Jiaxing;
Koch, Allison Ashley;
Cooke Bailey, Jessica N.;
Gharahkhani, Puya;
null, null;
MacGregor, Stuart;
Allingham, R. Rand;
Hauser, Michael A.;
Wiggs, Janey L.;
Geisert, Eldon E.

Publication type:

Article

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error.

Published in:

Nature Communications, 2016, v. 7, n. 3, p. 11008, doi. 10.1038/ncomms11008

By:

Fan, Qiao;
Verhoeven, Virginie J. M.;
Wojciechowski, Robert;
Barathi, Veluchamy A.;
Hysi, Pirro G.;
Guggenheim, Jeremy A.;
Höhn, René;
Vitart, Veronique;
Khawaja, Anthony P.;
Yamashiro, Kenji;
Hosseini, S Mohsen;
Lehtimäki, Terho;
Lu, Yi;
Haller, Toomas;
Xie, Jing;
Delcourt, Cécile;
Pirastu, Mario;
Wedenoja, Juho;
Gharahkhani, Puya;
Venturini, Cristina

Publication type:

Article

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process.

Published in:

Nature Communications, 2014, v. 5, n. 9, p. 4883, doi. 10.1038/ncomms5883

By:

Springelkamp, Henriët.;
Höhn, René;
Mishra, Aniket;
Hysi, Pirro G.;
Khor, Chiea-Chuen;
Loomis, Stephanie J.;
Bailey, Jessica N. Cooke;
Gibson, Jane;
Thorleifsson, Gudmar;
Janssen, Sarah F.;
Luo, Xiaoyan;
Ramdas, Wishal D.;
Vithana, Eranga;
Nongpiur, Monisha E.;
Montgomery, Grant W.;
Xu, Liang;
Mountain, Jenny E.;
Gharahkhani, Puya;
Lu, Yi;
Amin, Najaf

Publication type:

Article

Author Correction: Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization.

Published in:

2020

By:

Ong, Jue-Sheng;
Hwang, Liang-Dar;
Zhong, Victor W.;
An, Jiyuan;
Gharahkhani, Puya;
Breslin, Paul A. S.;
Wright, Margaret J.;
Lawlor, Deborah A.;
Whitfield, John;
MacGregor, Stuart;
Martin, Nicholas G.;
Corneli, Marilyn C.

Publication type:

Correction Notice

Author Correction: Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases.

Published in:

2019

By:

An, Jiyuan;
Gharahkhani, Puya;
Law, Matthew H.;
Ong, Jue-Sheng;
Han, Xikun;
Olsen, Catherine M.;
Neale, Rachel E.;
Lai, John;
Vaughan, Tom L.;
Gockel, Ines;
Thieme, René;
Böhmer, Anne C.;
Jankowski, Janusz;
Fitzgerald, Rebecca C.;
Schumacher, Johannes;
Palles, Claire;
BEACON;
Gammon, Marilie D.;
Corley, Douglas A.;
Shaheen, Nicholas J.

Publication type:

Correction Notice

Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11968-2

By:

An, Jiyuan;
Gharahkhani, Puya;
Law, Matthew H.;
Ong, Jue-Sheng;
Han, Xikun;
Olsen, Catherine M.;
Neale, Rachel E.;
Lai, John;
Vaughan, Tom L.;
Böhmer, Anne C.;
Jankowski, Janusz;
Fitzgerald, Rebecca C.;
Schumacher, Johannes;
Palles, Claire;
Whiteman, David C.;
MacGregor, Stuart

Publication type:

Article

Effect of increased body mass index on risk of diagnosis or death from cancer.

Published in:

2019

By:

Gharahkhani, Puya;
Ong, Jue-Sheng;
An, Jiyuan;
Law, Matthew H.;
Whiteman, David C.;
Neale, Rachel E.;
MacGregor, Stuart

Publication type:

journal article

Height and overall cancer risk and mortality: evidence from a Mendelian randomisation study on 310,000 UK Biobank participants.

Published in:

2018

By:

Ong, Jue-Sheng;
An, Jiyuan;
Law, Matthew H.;
Whiteman, David C.;
Neale, Rachel E.;
Gharahkhani, Puya;
MacGregor, Stuart

Publication type:

journal article

Macular structural integrity estimates are associated with Parkinson's disease genetic risk.

Published in:

Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01841-9

By:

Diaz-Torres, Santiago;
Lee, Samantha Sze-Yee;
Ogonowski, Natalia S.;
Mackey, David A.;
MacGregor, Stuart;
Gharahkhani, Puya;
Renteria, Miguel E.

Publication type:

Article

Integrating genetic regulation and single-cell expression with GWAS prioritizes causal genes and cell types for glaucoma.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-023-44380-y

By:

Hamel, Andrew R.;
Yan, Wenjun;
Rouhana, John M.;
Monovarfeshani, Aboozar;
Jiang, Xinyi;
Mehta, Puja A.;
Advani, Jayshree;
Luo, Yuyang;
Liang, Qingnan;
Rajasundaram, Skanda;
Shrivastava, Arushi;
Duchinski, Katherine;
Mantena, Sreekar;
Wang, Jiali;
van Zyl, Tavé;
Pasquale, Louis R.;
Swaroop, Anand;
Gharahkhani, Puya;
Khawaja, Anthony P.;
MacGregor, Stuart

Publication type:

Article

Bivariate genome-wide association analysis strengthens the role of bitter receptor clusters on chromosomes 7 and 12 in human bitter taste.

Published in:

BMC Genomics, 2018, v. 19, n. 1, p. 1, doi. 10.1186/s12864-018-5058-2

By:

Hwang, Liang-Dar;
Gharahkhani, Puya;
Breslin, Paul A. S.;
Gordon, Scott D.;
Zhu, Gu;
Martin, Nicholas G.;
Reed, Danielle R.;
Wright, Margaret J.

Publication type:

Article

Using Mendelian randomization to evaluate the causal relationship between serum C-reactive protein levels and age-related macular degeneration.

Published in:

European Journal of Epidemiology, 2020, v. 35, n. 2, p. 139, doi. 10.1007/s10654-019-00598-z

By:

Han, Xikun;
Ong, Jue-Sheng;
An, Jiyuan;
Hewitt, Alex W.;
Gharahkhani, Puya;
MacGregor, Stuart

Publication type:

Article