Found: 7

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  • A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25729-7
    By:
    • Beumer, Joep;
    • Geurts, Maarten H.;
    • Lamers, Mart M.;
    • Puschhof, Jens;
    • Zhang, Jingshu;
    • van der Vaart, Jelte;
    • Mykytyn, Anna Z.;
    • Breugem, Tim I.;
    • Riesebosch, Samra;
    • Schipper, Debby;
    • van den Doel, Petra B.;
    • de Lau, Wim;
    • Pleguezuelos-Manzano, Cayetano;
    • Busslinger, Georg;
    • Haagmans, Bart L.;
    • Clevers, Hans
    Publication type:
    Article

  • Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis.

    Published in:
    Nature Biotechnology, 2023, v. 41, n. 11, p. 1567, doi. 10.1038/s41587-023-01680-4
    By:
    • Hendriks, Delilah;
    • Brouwers, Jos F.;
    • Hamer, Karien;
    • Geurts, Maarten H.;
    • Luciana, Léa;
    • Massalini, Simone;
    • López-Iglesias, Carmen;
    • Peters, Peter J.;
    • Rodríguez-Colman, Maria J.;
    • Chuva de Sousa Lopes, Susana;
    • Artegiani, Benedetta;
    • Clevers, Hans
    Publication type:
    Article

  • Uncovering the mode of action of engineered T cells in patient cancer organoids.

    Published in:
    Nature Biotechnology, 2023, v. 41, n. 1, p. 60, doi. 10.1038/s41587-022-01397-w
    By:
    • Dekkers, Johanna F.;
    • Alieva, Maria;
    • Cleven, Astrid;
    • Keramati, Farid;
    • Wezenaar, Amber K. L.;
    • van Vliet, Esmée J.;
    • Puschhof, Jens;
    • Brazda, Peter;
    • Johanna, Inez;
    • Meringa, Angelo D.;
    • Rebel, Heggert G.;
    • Buchholz, Maj-Britt;
    • Barrera Román, Mario;
    • Zeeman, Amber L.;
    • de Blank, Sam;
    • Fasci, Domenico;
    • Geurts, Maarten H.;
    • Cornel, Annelisa M.;
    • Driehuis, Else;
    • Millen, Rosemary
    Publication type:
    Article

  • One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40701-3
    By:
    • Geurts, Maarten H.;
    • Gandhi, Shashank;
    • Boretto, Matteo G.;
    • Akkerman, Ninouk;
    • Derks, Lucca L. M.;
    • van Son, Gijs;
    • Celotti, Martina;
    • Harshuk-Shabso, Sarina;
    • Peci, Flavia;
    • Begthel, Harry;
    • Hendriks, Delilah;
    • Schürmann, Paul;
    • Andersson-Rolf, Amanda;
    • Chuva de Sousa Lopes, Susana M.;
    • van Es, Johan H.;
    • van Boxtel, Ruben;
    • Clevers, Hans
    Publication type:
    Article

  • Modelling of primary ciliary dyskinesia using patient‐derived airway organoids.

    Published in:
    EMBO Reports, 2021, v. 22, n. 12, p. 1, doi. 10.15252/embr.202052058
    By:
    • van der Vaart, Jelte;
    • Böttinger, Lena;
    • Geurts, Maarten H;
    • van de Wetering, Willine J;
    • Knoops, Kèvin;
    • Sachs, Norman;
    • Begthel, Harry;
    • Korving, Jeroen;
    • Lopez‐Iglesias, Carmen;
    • Peters, Peter J;
    • Eitan, Kerem;
    • Gileles‐Hillel, Alex;
    • Clevers, Hans
    Publication type:
    Article

  • Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoids.

    Published in:
    Life Science Alliance, 2021, v. 4, n. 10, p. 1, doi. 10.26508/lsa.202000940
    By:
    • Geurts, Maarten H.;
    • de Poel, Eyleen;
    • Pleguezuelos-Manzano, Cayetano;
    • Oka, Rurika;
    • Carrillo, Leo;
    • Andersson-Rolf, Amanda;
    • Boretto, Matteo;
    • Brunsveld, Jesse E.;
    • van Boxtel, Ruben;
    • Beekman, Jeffrey M.;
    • Clevers, Hans
    Publication type:
    Article

  • Modeling Breast Cancer Using CRISPR-Cas9-Mediated Engineering of Human Breast Organoids.

    Published in:
    2020
    By:
    • Dekkers, Johanna F;
    • Whittle, James R;
    • Vaillant, François;
    • Chen, Huei-Rong;
    • Dawson, Caleb;
    • Liu, Kevin;
    • Geurts, Maarten H;
    • Herold, Marco J;
    • Clevers, Hans;
    • Lindeman, Geoffrey J;
    • Visvader, Jane E
    Publication type:
    journal article