Works by Gerwert, Klaus

Results: 96

Front Cover: Lamprey Parapinopsin ("UVLamP"): a Bistable UV‐Sensitive Optogenetic Switch for Ultrafast Control of GPCR Pathways (ChemBioChem 5/2020).

Published in:

ChemBioChem, 2020, v. 21, n. 5, p. 572, doi. 10.1002/cbic.201900720

By:

Eickelbeck, Dennis;
Rudack, Till;
Tennigkeit, Stefan Alexander;
Surdin, Tatjana;
Karapinar, Raziye;
Schwitalla, Jan‐Claudius;
Mücher, Brix;
Shulman, Maiia;
Scherlo, Marvin;
Althoff, Philipp;
Mark, Melanie D.;
Gerwert, Klaus;
Herlitze, Stefan

Publication type:

Article

Lamprey Parapinopsin ("UVLamP"): a Bistable UV‐Sensitive Optogenetic Switch for Ultrafast Control of GPCR Pathways.

Published in:

ChemBioChem, 2020, v. 21, n. 5, p. 612, doi. 10.1002/cbic.201900485

By:

Eickelbeck, Dennis;
Rudack, Till;
Tennigkeit, Stefan Alexander;
Surdin, Tatjana;
Karapinar, Raziye;
Schwitalla, Jan‐Claudius;
Mücher, Brix;
Shulman, Maiia;
Scherlo, Marvin;
Althoff, Philipp;
Mark, Melanie D.;
Gerwert, Klaus;
Herlitze, Stefan

Publication type:

Article

Cover Feature: Design of an Ultrafast G Protein Switch Based on a Mouse Melanopsin Variant (ChemBioChem 14/2019).

Published in:

ChemBioChem, 2019, v. 20, n. 14, p. 1728, doi. 10.1002/cbic.201900409

By:

Tennigkeit, Stefan Alexander;
Karapinar, Raziye;
Rudack, Till;
Dreier, Max‐Aylmer;
Althoff, Philipp;
Eickelbeck, Dennis;
Surdin, Tatjana;
Grömmke, Michelle;
Mark, Melanie D.;
Spoida, Katharina;
Lübben, Mathias;
Höweler, Udo;
Herlitze, Stefan;
Gerwert, Klaus

Publication type:

Article

Design of an Ultrafast G Protein Switch Based on a Mouse Melanopsin Variant.

Published in:

ChemBioChem, 2019, v. 20, n. 14, p. 1766, doi. 10.1002/cbic.201900110

By:

Tennigkeit, Stefan Alexander;
Karapinar, Raziye;
Rudack, Till;
Dreier, Max‐Aylmer;
Althoff, Philipp;
Eickelbeck, Dennis;
Surdin, Tatjana;
Grömmke, Michelle;
Mark, Melanie D.;
Spoida, Katharina;
Lübben, Mathias;
Höweler, Udo;
Herlitze, Stefan;
Gerwert, Klaus

Publication type:

Article

Immobilization of Proteins in their Physiological Active State at Functionalized Thiol Monolayers on ATRGermanium Crystals.

Published in:

ChemBioChem, 2014, v. 15, n. 17, p. 2529, doi. 10.1002/cbic.201402478

By:

Schartner, Jonas;
Gavriljuk, Konstantin;
Nabers, Andreas;
Weide, Philipp;
Muhler, Martin;
Gerwert, Klaus;
Kötting, Carsten

Publication type:

Article

Vorhersage der Ligandenerkennung in einem Geruchsrezeptor durch Kombination von ortsgerichteter Mutagenese und dynamischer Homologie-Modellierung.

Published in:

Angewandte Chemie, 2012, v. 124, n. 5, p. 1300, doi. 10.1002/ange.201103980

By:

Gelis, Lian;
Wolf, Steffen;
Hatt, Hanns;
Neuhaus, Eva M.;
Gerwert, Klaus

Publication type:

Article

Titelbild: Vorhersage der Ligandenerkennung in einem Geruchsrezeptor durch Kombination von ortsgerichteter Mutagenese und dynamischer Homologie-Modellierung (Angew. Chem. 5/2012).

Published in:

Angewandte Chemie, 2012, v. 124, n. 5, p. 1105, doi. 10.1002/ange.201107509

By:

Gelis, Lian;
Wolf, Steffen;
Hatt, Hanns;
Neuhaus, Eva M.;
Gerwert, Klaus

Publication type:

Article

Gerichteter Protonentransfer in Membranproteinen mittels protonierter proteingebundener Wassermoleküle: eine Protonendiode.

Published in:

Angewandte Chemie, 2010, v. 122, n. 38, p. 7041, doi. 10.1002/ange.201001243

By:

Wolf, Steffen;
Freier, Erik;
Potschies, Meike;
Hofmann, Eckhard;
Gerwert, Klaus

Publication type:

Article

Integrating spatial, morphological, and textural information for improved cell type differentiation using Raman microscopy.

Published in:

Journal of Chemometrics, 2018, v. 32, n. 1, p. 1, doi. 10.1002/cem.2973

By:

Krauß, Sascha D.;
Yosef, Hesham K.;
Lechtonen, Tatjana;
Jütte, Hendrik;
Tannapfel, Andrea;
Käfferlein, Heiko U.;
Brüning, Thomas;
Roghmann, Florian;
Noldus, Joachim;
El-Mashtoly, Samir F.;
Gerwert, Klaus;
Mosig, Axel

Publication type:

Article

A structure‐based fluid biomarker for the differential diagnosis of early‐stage neurodegenerative diseases measured by the immuno‐infrared‐sensor (iRS).

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082847

By:

Schuler, Martin;
Mann, Marvin;
Langenhoff, Lennart Carl;
Budde, Brian;
Beyer, Léon;
Woitzik, Nathalie;
Gerwert, Grischa;
Wanka, Robin;
Hoeveler, Adrian;
Dreier, Max‐Aylmer;
Hubert, Diana;
Galkowski, Sandy;
Güldenhaupt, Jörn;
Kötting, Carsten;
Gerwert, Klaus Bernhard

Publication type:

Article

Zeitaufgelöst und markerfrei gemessene ligandeninduzierte Konformationsänderungen von HSP90 – hin zu einem Konformationsaktivitätsscreening für die Wirkstoffentwicklung.

Published in:

Angewandte Chemie, 2018, v. 130, n. 31, p. 10103, doi. 10.1002/ange.201802603

By:

Güldenhaupt, Jörn;
Amaral, Marta;
Kötting, Carsten;
Schartner, Jonas;
Musil, Djordje;
Frech, Matthias;
Gerwert, Klaus

Publication type:

Article

Functional waters in intraprotein proton transfer monitored by FTIR difference spectroscopy.

Published in:

2006

By:

Garczarek, Florian;
Gerwert, Klaus

Publication type:

Letter

Time-resolved spectroscopic and electrophysiological data reveal insights in the gating mechanism of anion channelrhodopsin.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02101-5

By:

Dreier, Max-Aylmer;
Althoff, Philipp;
Norahan, Mohamad Javad;
Tennigkeit, Stefan Alexander;
El-Mashtoly, Samir F.;
Lübben, Mathias;
Kötting, Carsten;
Rudack, Till;
Gerwert, Klaus

Publication type:

Article

Association of Kidney Function With Development of Alzheimer Disease and Other Dementias and Dementia-Related Blood Biomarkers.

Published in:

JAMA Network Open, 2023, v. 6, n. 1, p. e2252387, doi. 10.1001/jamanetworkopen.2022.52387

By:

Stocker, Hannah;
Beyer, Léon;
Trares, Kira;
Perna, Laura;
Rujescu, Dan;
Holleczek, Bernd;
Beyreuther, Konrad;
Gerwert, Klaus;
Schöttker, Ben;
Brenner, Hermann

Publication type:

Article

Correction: Comparison of the molecular properties of retinitis pigmentosa P23H and N15S amino acid replacements in rhodopsin.

Published in:

2019

By:

Mitchell, James;
Balem, Fernanda;
Tirupula, Kalyan;
Man, David;
Dhiman, Harpreet Kaur;
Yanamala, Naveena;
Ollesch, Julian;
Planas-Iglesias, Joan;
Jennings, Barbara J.;
Gerwert, Klaus;
Iannaccone, Alessandro;
Klein-Seetharaman, Judith

Publication type:

Correction Notice

Water dynamics simulation as a tool for probing proton transfer pathways in a heptahelical membrane protein.

Published in:

Proteins, 2005, v. 58, n. 3, p. 528, doi. 10.1002/prot.20343

By:

Kandt, Christian;
Gerwert, Klaus;
Schlitter, Jürgen

Publication type:

Article

Spectroscopic investigation of the reaction mechanism of CopB-B, the catalytic fragment from an archaeal thermophilic ATP-driven heavy metal transporter.

Published in:

FEBS Journal, 2009, v. 276, n. 21, p. 6172, doi. 10.1111/j.1742-4658.2009.07320.x

By:

Völlmecke, Christian;
Kötting, Carsten;
Gerwert, Klaus;
Lübben, Mathias

Publication type:

Article

Secondary structure of lipidated Ras bound to a lipid bilayer.

Published in:

FEBS Journal, 2008, v. 275, n. 23, p. 5910, doi. 10.1111/j.1742-4658.2008.06720.x

By:

Güldenhaupt, Jörn;
Adigüzel, Yekbun;
Kuhlmann, Jürgen;
Waldmann, Herbert;
Kötting, Carsten;
Gerwert, Klaus

Publication type:

Article

Light-induced reactions of Escherichia coli DNA photolyase monitored by Fourier transform infrared spectroscopy.

Published in:

FEBS Journal, 2005, v. 272, n. 8, p. 1855, doi. 10.1111/j.1742-4658.2005.04617.x

By:

Schleicher, Erik;
Heßling, Benedikt;
Illarionova, Viktoria;
Bacher, Adelbert;
Weber, Stefan;
Richter, Gerald;
Gerwert, Klaus

Publication type:

Article

Highlight: GTP- and ATP-dependent membrane processes.

Published in:

Biological Chemistry, 2017, v. 398, n. 5/6, p. 519, doi. 10.1515/hsz-2017-0132

By:

Gerwert, Klaus

Publication type:

Article

Common mechanisms of catalysis in small and heterotrimeric GTPases and their respective GAPs.

Published in:

Biological Chemistry, 2017, v. 398, n. 5/6, p. 523, doi. 10.1515/hsz-2016-0314

By:

Gerwert, Klaus;
Mann, Daniel;
Kötting, Carsten

Publication type:

Article

What vibrations tell us about GTPases.

Published in:

Biological Chemistry, 2015, v. 396, n. 2, p. 131, doi. 10.1515/hsz-2014-0219

By:

Kötting, Carsten;
Gerwert, Klaus

Publication type:

Article

Cover Picture: Surface-Attached Polyhistidine-Tag Proteins Characterized by FTIR Difference Spectroscopy (ChemPhysChem 11/2012).

Published in:

ChemPhysChem, 2012, v. 13, n. 11, p. 2617, doi. 10.1002/cphc.201290051

By:

Pinkerneil, Philipp;
Güldenhaupt, Jörn;
Gerwert, Klaus;
Kötting, Carsten

Publication type:

Article

Surface-Attached Polyhistidine-Tag Proteins Characterized by FTIR Difference Spectroscopy.

Published in:

ChemPhysChem, 2012, v. 13, n. 11, p. 2649, doi. 10.1002/cphc.201200358

By:

Pinkerneil, Philipp;
Güldenhaupt, Jörn;
Gerwert, Klaus;
Kötting, Carsten

Publication type:

Article

How Does a Membrane Protein Achieve a Vectorial Proton Transfer Via Water Molecules?

Published in:

ChemPhysChem, 2008, v. 9, n. 18, p. 2772, doi. 10.1002/cphc.200800703

By:

Wolf, Steffen;
Freier, Erik;
Gerwert, Klaus

Publication type:

Article

Proteins in Action Monitored by Time-Resolved FTIR Spectroscopy.

Published in:

ChemPhysChem, 2005, v. 6, n. 5, p. 881, doi. 10.1002/cphc.200400504

By:

Carsten Ktting;
Klaus Gerwert

Publication type:

Article

CaMello-XR enables visualization and optogenetic control of G<sub>q/11</sub> signals and receptor trafficking in GPCR-specific domains.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0292-y

By:

Eickelbeck, Dennis;
Karapinar, Raziye;
Jack, Alexander;
Suess, Sandra T.;
Barzan, Ruxandra;
Azimi, Zohre;
Surdin, Tatjana;
Grömmke, Michelle;
Mark, Melanie D.;
Gerwert, Klaus;
Jancke, Dirk;
Wahle, Petra;
Spoida, Katharina;
Herlitze, Stefan

Publication type:

Article

Prediction of a Ligand-Binding Niche within a Human Olfactory Receptor by Combining Site-Directed Mutagenesis with Dynamic Homology Modeling.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 5, p. 1274, doi. 10.1002/anie.201103980

By:

Gelis, Lian;
Wolf, Steffen;
Hatt, Hanns;
Neuhaus, Eva M.;
Gerwert, Klaus

Publication type:

Article

Cover Picture: Prediction of a Ligand-Binding Niche within a Human Olfactory Receptor by Combining Site-Directed Mutagenesis with Dynamic Homology Modeling (Angew. Chem. Int. Ed. 5/2012).

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 5, p. 1079, doi. 10.1002/anie.201107509

By:

Gelis, Lian;
Wolf, Steffen;
Hatt, Hanns;
Neuhaus, Eva M.;
Gerwert, Klaus

Publication type:

Article

Directional Proton Transfer in Membrane Proteins Achieved through Protonated Protein-Bound Water Molecules: A Proton Diode.

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 38, p. 6889, doi. 10.1002/anie.201001243

By:

Wolf, Steffen;
Freier, Erik;
Potschies, Meike;
Hofmann, Eckhard;
Gerwert, Klaus

Publication type:

Article

Label-free identification of myopathological features with coherent anti-Stokes Raman scattering.

Published in:

2018

By:

Niedieker, Daniel;
GrosserÜschkamp, Frederik;
Schreiner, Anja;
Barkovits, Katalin;
Kötting, Carsten;
Marcus, Katrin;
Gerwert, Klaus;
Vorgerd, Matthias

Publication type:

journal article

Subjective cognitive complaints and blood biomarkers of neurodegenerative diseases: a longitudinal cohort study.

Published in:

Alzheimer's Research & Therapy, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13195-023-01341-3

By:

Perna, Laura;
Stocker, Hannah;
Burow, Lena;
Beyer, Léon;
Trares, Kira;
Kurz, Carolin;
Gürsel, Selim;
Holleczek, Bernd;
Tatò, Maia;
Beyreuther, Konrad;
Mons, Ute;
Gerwert, Klaus;
Perneczky, Robert;
Schöttker, Ben;
Brenner, Hermann

Publication type:

Article

Alzheimer's polygenic risk scores, APOE, Alzheimer's disease risk, and dementia-related blood biomarker levels in a population-based cohort study followed over 17 years.

Published in:

Alzheimer's Research & Therapy, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13195-023-01277-8

By:

Stocker, Hannah;
Trares, Kira;
Beyer, Léon;
Perna, Laura;
Rujescu, Dan;
Holleczek, Bernd;
Beyreuther, Konrad;
Gerwert, Klaus;
Schöttker, Ben;
Brenner, Hermann

Publication type:

Article

Serum neurofilament light chain does not detect self‐reported treatment‐related fluctuations in chronic inflammatory demyelinating polyneuropathy.

Published in:

European Journal of Neurology, 2024, v. 31, n. 1, p. 1, doi. 10.1111/ene.16023

By:

Poser, Philip Lennart;
Sajid, Gulchan Shazadi;
Beyer, Léon;
Hieke, Alina;
Schumacher, Aurelian;
Horstkemper, Lea;
Karl, Anna‐Sophia;
Grüter, Thomas;
Sgodzai, Melissa;
Pitarokoili, Kalliopi;
Gerwert, Klaus;
Gold, Ralf;
Fisse, Anna Lena;
Gisevius, Barbara;
Motte, Jeremias

Publication type:

Article

Deep representation learning for domain adaptable classification of infrared spectral imaging data.

Published in:

Bioinformatics, 2020, v. 36, n. 1, p. 287, doi. 10.1093/bioinformatics/btz505

By:

Raulf, Arne P;
Butke, Joshua;
Küpper, Claus;
Großerueschkamp, Frederik;
Gerwert, Klaus;
Mosig, Axel

Publication type:

Article

Amyloid blood biomarker detects Alzheimer's disease.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 5, p. 1, doi. 10.15252/emmm.201708763

By:

Nabers, Andreas;
Perna, Laura;
Lange, Julia;
Mons, Ute;
Schartner, Jonas;
Güldenhaupt, Jörn;
Saum, Kai‐Uwe;
Janelidze, Shorena;
Holleczek, Bernd;
Rujescu, Dan;
Hansson, Oskar;
Gerwert, Klaus;
Brenner, Hermann

Publication type:

Article

The dynamics of the catalytic site in small GTPases, variations on a common motif.

Published in:

FEBS Letters, 2013, v. 587, n. 13, p. 2025, doi. 10.1016/j.febslet.2013.05.021

By:

Kötting, Carsten;
Gerwert, Klaus

Publication type:

Article

The structure of active opsin as a basis for identification of GPCR agonists by dynamic homology modelling and virtual screening assays

Published in:

FEBS Letters, 2011, v. 585, n. 22, p. 3587, doi. 10.1016/j.febslet.2011.10.027

By:

Schneider, Michael;
Wolf, Steffen;
Schlitter, Jürgen;
Gerwert, Klaus

Publication type:

Article

Simulations of a G protein-coupled receptor homology model predict dynamic features and a ligand binding site

Published in:

FEBS Letters, 2008, v. 582, n. 23/24, p. 3335, doi. 10.1016/j.febslet.2008.08.022

By:

Wolf, Steffen;
Böckmann, Marcus;
Höweler, Udo;
Schlitter, Jürgen;
Gerwert, Klaus

Publication type:

Article

Role of the arginine finger in Ras·RasGAP revealed by QM/MM calculations

Published in:

FEBS Letters, 2007, v. 581, n. 29, p. 5677, doi. 10.1016/j.febslet.2007.11.026

By:

te Heesen, Henrik;
Gerwert, Klaus;
Schlitter, Jürgen

Publication type:

Article

Monitoring transient events in infrared spectra using local mode analysis.

Published in:

Proteins, 2018, v. 86, n. 10, p. 1013, doi. 10.1002/prot.25536

By:

Massarczyk, Matthias;
Schlitter, Jürgen;
Kötting, Carsten;
Rudack, Till;
Gerwert, Klaus

Publication type:

Article

Unsaturated Fatty Acids Are Decreased in Aβ Plaques in Alzheimer's Disease.

Published in:

Journal of Neurochemistry, 2025, v. 169, n. 1, p. 1, doi. 10.1111/jnc.16306

By:

Röhr, Dominik;
Helfrich, Melina;
Höring, Marcus;
Großerüschkamp, Frederik;
Liebisch, Gerhard;
Gerwert, Klaus

Publication type:

Article

Fully automated registration of vibrational microspectroscopic images in histologically stained tissue sections.

Published in:

BMC Bioinformatics, 2015, v. 16, p. 1, doi. 10.1186/s12859-015-0804-9

By:

Chen Yang;
Niedieker, Daniel;
Großerüschkamp, Frederik;
Horn, Melanie;
Tannapfel, Andrea;
Kallenbach-Thieltges, Angela;
Gerwert, Klaus;
Mosig, Axel

Publication type:

Article

Cover Picture: Surface Change of Ras Enabling Effector Binding Monitored in Real Time at Atomic Resolution (ChemBioChem 7/2007).

Published in:

ChemBioChem, 2007, v. 8, n. 7, p. 693, doi. 10.1002/cbic.200790016

By:

Kötting, Carsten;
Kallenbach, Angela;
Suveyzdis, Yan;
Eichholz, Carolin;
Gerwert, Klaus

Publication type:

Article

Surface Change of Ras Enabling Effector Binding Monitored in Real Time at Atomic Resolution.

Published in:

ChemBioChem, 2007, v. 8, n. 7, p. 781, doi. 10.1002/cbic.200600552

By:

Kötting, Carsten;
Kallenbach, Angela;
Suveyzdis, Yan;
Eichholz, Carolin;
Gerwert, Klaus

Publication type:

Article

Genetic predisposition, Aβ misfolding in blood plasma, and Alzheimer's disease.

Published in:

Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01380-0

By:

Stocker, Hannah;
Nabers, Andreas;
Perna, Laura;
Möllers, Tobias;
Rujescu, Dan;
Hartmann, Annette M.;
Holleczek, Bernd;
Schöttker, Ben;
Stockmann, Julia;
Gerwert, Klaus;
Brenner, Hermann

Publication type:

Article

Genetic predisposition, Aβ misfolding in blood plasma, and Alzheimer's disease.

Published in:

Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01380-0

By:

Stocker, Hannah;
Nabers, Andreas;
Perna, Laura;
Möllers, Tobias;
Rujescu, Dan;
Hartmann, Annette M.;
Holleczek, Bernd;
Schöttker, Ben;
Stockmann, Julia;
Gerwert, Klaus;
Brenner, Hermann

Publication type:

Article

Raman micro-spectroscopy monitors acquired resistance to targeted cancer therapy at the cellular level.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-33682-7

By:

Hammoud, Mohamad K.;
Yosef, Hesham K.;
Lechtonen, Tatjana;
Aljakouch, Karim;
Schuler, Martin;
Alsaidi, Wissam;
Daho, Ibrahim;
Maghnouj, Abdelouahid;
Hahn, Stephan;
El-Mashtoly, Samir F.;
Gerwert, Klaus

Publication type:

Article

Update on CSF Biomarkers in Parkinson's Disease.

Published in:

Biomolecules (2218-273X), 2022, v. 12, n. 2, p. 329, doi. 10.3390/biom12020329

By:

Kwon, Eun Hae;
Tennagels, Sabrina;
Gold, Ralf;
Gerwert, Klaus;
Beyer, Léon;
Tönges, Lars

Publication type:

Article

Assessment of MYC and TERT copy number variations in lung cancer using digital PCR.

Published in:

BMC Research Notes, 2023, v. 16, n. 1, p. 1, doi. 10.1186/s13104-023-06566-x

By:

Brik, Alexander;
Wichert, Katharina;
Weber, Daniel G.;
Szafranski, Katja;
Rozynek, Peter;
Meier, Swetlana;
Ko, Yon-Dschun;
Büttner, Reinhard;
Gerwert, Klaus;
Behrens, Thomas;
Brüning, Thomas;
Johnen, Georg

Publication type:

Article