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Zeitaufgelöst und markerfrei gemessene ligandeninduzierte Konformationsänderungen von HSP90 – hin zu einem Konformationsaktivitätsscreening für die Wirkstoffentwicklung.
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- Angewandte Chemie, 2018, v. 130, n. 31, p. 10103, doi. 10.1002/ange.201802603
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- Publication type:
- Article
Raman‐mikrospektroskopischer Nachweis für den Metabolismus eines Tyrosinkinase‐Inhibitors, Neratinib, in Krebszellen.
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- Angewandte Chemie, 2018, v. 130, n. 24, p. 7370, doi. 10.1002/ange.201803394
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- Publication type:
- Article
[FeFe]-Hydrogenase with Chalcogenide Substitutions at the H-Cluster Maintains Full H<sub>2</sub> Evolution Activity.
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- Angewandte Chemie, 2016, v. 128, n. 29, p. 8536, doi. 10.1002/ange.201511896
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- Article
Die frühe Entstehung der ionenleitenden Pore in Channelrhodopsin-2.
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- Angewandte Chemie, 2015, v. 127, n. 16, p. 5037, doi. 10.1002/ange.201410180
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- Publication type:
- Article
Rücktitelbild: Die frühe Entstehung der ionenleitenden Pore in Channelrhodopsin-2 (Angew. Chem. 16/2015).
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- Angewandte Chemie, 2015, v. 127, n. 16, p. 5054, doi. 10.1002/ange.201502275
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- Publication type:
- Article
Aβ misfolding in blood plasma is inversely associated with body mass index even in middle adulthood.
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- Alzheimer's Research & Therapy, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13195-021-00889-2
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- Publication type:
- Article
Prediction of a Ligand-Binding Niche within a Human Olfactory Receptor by Combining Site-Directed Mutagenesis with Dynamic Homology Modeling.
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- Angewandte Chemie International Edition, 2012, v. 51, n. 5, p. 1274, doi. 10.1002/anie.201103980
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- Article
Cover Picture: Prediction of a Ligand-Binding Niche within a Human Olfactory Receptor by Combining Site-Directed Mutagenesis with Dynamic Homology Modeling (Angew. Chem. Int. Ed. 5/2012).
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- Angewandte Chemie International Edition, 2012, v. 51, n. 5, p. 1079, doi. 10.1002/anie.201107509
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- Publication type:
- Article
Directional Proton Transfer in Membrane Proteins Achieved through Protonated Protein-Bound Water Molecules: A Proton Diode.
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- Angewandte Chemie International Edition, 2010, v. 49, n. 38, p. 6889, doi. 10.1002/anie.201001243
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- Publication type:
- Article
The dynamics of the catalytic site in small GTPases, variations on a common motif.
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- FEBS Letters, 2013, v. 587, n. 13, p. 2025, doi. 10.1016/j.febslet.2013.05.021
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- Article
The structure of active opsin as a basis for identification of GPCR agonists by dynamic homology modelling and virtual screening assays
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- FEBS Letters, 2011, v. 585, n. 22, p. 3587, doi. 10.1016/j.febslet.2011.10.027
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- Article
Functional waters in intraprotein proton transfer monitored by FTIR difference spectroscopy.
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- 2006
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- Publication type:
- Letter
Raman micro-spectroscopy monitors acquired resistance to targeted cancer therapy at the cellular level.
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- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-33682-7
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- Article
Assessment of MYC and TERT copy number variations in lung cancer using digital PCR.
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- BMC Research Notes, 2023, v. 16, n. 1, p. 1, doi. 10.1186/s13104-023-06566-x
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- Article
Fully automated registration of vibrational microspectroscopic images in histologically stained tissue sections.
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- BMC Bioinformatics, 2015, v. 16, p. 1, doi. 10.1186/s12859-015-0804-9
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- Publication type:
- Article
Similarity maps and hierarchical clustering for annotating FT-IR spectral images.
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- BMC Bioinformatics, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2105-14-333
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- Publication type:
- Article
The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson's disease brain as revealed by multicolor STED microscopy.
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- Acta Neuropathologica, 2021, v. 142, n. 3, p. 423, doi. 10.1007/s00401-021-02329-9
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- Publication type:
- Article
CaMello-XR enables visualization and optogenetic control of G<sub>q/11</sub> signals and receptor trafficking in GPCR-specific domains.
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- Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0292-y
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- Publication type:
- Article
TDP‐43 as structure‐based biomarker in amyotrophic lateral sclerosis.
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- Annals of Clinical & Translational Neurology, 2021, v. 8, n. 1, p. 271, doi. 10.1002/acn3.51256
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- Publication type:
- Article
Label-free vibrational imaging of different Aβ plaque types in Alzheimer's disease reveals sequential events in plaque development.
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- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-01091-5
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- Publication type:
- Article
Amyloid blood biomarker detects Alzheimer's disease.
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- EMBO Molecular Medicine, 2018, v. 10, n. 5, p. 1, doi. 10.15252/emmm.201708763
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- Publication type:
- Article
Ligand‐Induced Conformational Changes in HSP90 Monitored Time Resolved and Label Free—Towards a Conformational Activity Screening for Drug Discovery.
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- Angewandte Chemie International Edition, 2018, v. 57, n. 31, p. 9955, doi. 10.1002/anie.201802603
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- Publication type:
- Article
Raman Microspectroscopic Evidence for the Metabolism of a Tyrosine Kinase Inhibitor, Neratinib, in Cancer Cells.
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- Angewandte Chemie International Edition, 2018, v. 57, n. 24, p. 7250, doi. 10.1002/anie.201803394
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- Publication type:
- Article
[FeFe]-Hydrogenase with Chalcogenide Substitutions at the H-Cluster Maintains Full H<sub>2</sub> Evolution Activity.
- Published in:
- Angewandte Chemie International Edition, 2016, v. 55, n. 29, p. 8396, doi. 10.1002/anie.201511896
- By:
- Publication type:
- Article
Early Formation of the Ion-Conducting Pore in Channelrhodopsin-2.
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- Angewandte Chemie International Edition, 2015, v. 54, n. 16, p. 4953, doi. 10.1002/anie.201410180
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- Publication type:
- Article
Back Cover: Early Formation of the Ion-Conducting Pore in Channelrhodopsin-2 (Angew. Chem. Int. Ed. 16/2015).
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- Angewandte Chemie International Edition, 2015, v. 54, n. 16, p. 4970, doi. 10.1002/anie.201502275
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- Publication type:
- Article
Aβ misfolding in blood plasma measured by immuno-infrared-sensor as an age-independent risk marker of Alzheimer’s disease.
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- Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021, v. 13, n. 1, p. 1, doi. 10.1002/dad2.12151
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- Publication type:
- Article
Advances in Digital Pathology: From Artificial Intelligence to Label-Free Imaging.
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- Visceral Medicine, 2021, v. 37, n. 6, p. 482, doi. 10.1159/000518494
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- Article
Generation of mid‐region murine monoclonal antibodies against multiple structural isoforms of amyloid‐beta by hybridoma technology: Biomarkers (non‐neuroimaging) / plasma/serum/urine biomarkers.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043577
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- Publication type:
- Article
Investigating Aβ plaque development using FTIR micro‐spectroscopy on native postmortem human brain tissue: Human neuropathology/imaging‐pathologic correlations.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043289
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- Publication type:
- Article
Throughput optimized immuno‐infrared‐assay for Alzheimer's disease diagnosis: Biomarkers (non‐neuroimaging) / Method development and/or quality control.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043093
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- Publication type:
- Article
Prediction of Alzheimer's disease diagnosis within 14 years through Aβ misfolding in blood plasma compared to APOE4 status, and other risk factors.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 2, p. 283, doi. 10.1016/j.jalz.2019.08.189
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- Article
Titelbild: Vorhersage der Ligandenerkennung in einem Geruchsrezeptor durch Kombination von ortsgerichteter Mutagenese und dynamischer Homologie-Modellierung (Angew. Chem. 5/2012).
- Published in:
- Angewandte Chemie, 2012, v. 124, n. 5, p. 1105, doi. 10.1002/ange.201107509
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- Publication type:
- Article
Vorhersage der Ligandenerkennung in einem Geruchsrezeptor durch Kombination von ortsgerichteter Mutagenese und dynamischer Homologie-Modellierung.
- Published in:
- Angewandte Chemie, 2012, v. 124, n. 5, p. 1300, doi. 10.1002/ange.201103980
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- Publication type:
- Article
Gerichteter Protonentransfer in Membranproteinen mittels protonierter proteingebundener Wassermoleküle: eine Protonendiode.
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- Angewandte Chemie, 2010, v. 122, n. 38, p. 7041, doi. 10.1002/ange.201001243
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- Publication type:
- Article
Deep representation learning for domain adaptable classification of infrared spectral imaging data.
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- Bioinformatics, 2020, v. 36, n. 1, p. 287, doi. 10.1093/bioinformatics/btz505
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- Publication type:
- Article
Label-free, automated classification of microsatellite status in colorectal cancer by infrared imaging.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-67052-z
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- Publication type:
- Article
Subjective cognitive complaints and blood biomarkers of neurodegenerative diseases: a longitudinal cohort study.
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- Alzheimer's Research & Therapy, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13195-023-01341-3
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- Publication type:
- Article
Alzheimer's polygenic risk scores, APOE, Alzheimer's disease risk, and dementia-related blood biomarker levels in a population-based cohort study followed over 17 years.
- Published in:
- Alzheimer's Research & Therapy, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13195-023-01277-8
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- Publication type:
- Article
A representation learning approach for recovering scatter‐corrected spectra from Fourier‐transform infrared spectra of tissue samples.
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- Journal of Biophotonics, 2021, v. 14, n. 3, p. 1, doi. 10.1002/jbio.202000385
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- Publication type:
- Article
Grayscale representation of infrared microscopy images by extended multiplicative signal correction for registration with histological images.
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- Journal of Biophotonics, 2020, v. 13, n. 8, p. 1, doi. 10.1002/jbio.201960223
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- Publication type:
- Article
An open‐source code for Mie extinction extended multiplicative signal correction for infrared microscopy spectra of cells and tissues.
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- Journal of Biophotonics, 2019, v. 12, n. 8, p. N.PAG, doi. 10.1002/jbio.201800415
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- Publication type:
- Article
Inside Cover: Hierarchical deep convolutional neural networks combine spectral and spatial information for highly accurate Raman‐microscopy‐based cytopathology (J. Biophotonics 10/2018).
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- Journal of Biophotonics, 2018, v. 11, n. 10, p. N.PAG, doi. 10.1002/jbio.201870163
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- Publication type:
- Article
Hierarchical deep convolutional neural networks combine spectral and spatial information for highly accurate Raman‐microscopy‐based cytopathology.
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- Journal of Biophotonics, 2018, v. 11, n. 10, p. N.PAG, doi. 10.1002/jbio.201800022
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- Publication type:
- Article
An infrared sensor analysing label-free the secondary structure of the Abeta peptide in presence of complex fluids.
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- Journal of Biophotonics, 2016, v. 9, n. 3, p. 224, doi. 10.1002/jbio.201400145
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- Publication type:
- Article
It's in your blood: spectral biomarker candidates for urinary bladder cancer from automated FTIR spectroscopy.
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- Journal of Biophotonics, 2014, v. 7, n. 3/4, p. 210, doi. 10.1002/jbio.201300163
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- Publication type:
- Article
Immunohistochemistry, histopathology and infrared spectral histopathology of colon cancer tissue sections.
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- Journal of Biophotonics, 2013, v. 6, n. 1, p. 88, doi. 10.1002/jbio.201200132
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- Publication type:
- Article
Nanoscale distinction of membrane patches - a TERS study of Halobacterium salinarum.
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- Journal of Biophotonics, 2012, v. 5, n. 7, p. 582, doi. 10.1002/jbio.201100131
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- Publication type:
- Article
In vitro prediction of the efficacy of molecularly targeted cancer therapy by Raman spectral imaging.
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- Analytical & Bioanalytical Chemistry, 2015, v. 407, n. 27, p. 8321, doi. 10.1007/s00216-015-8875-z
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- Publication type:
- Article
Spatial and molecular resolution of diffuse malignant mesothelioma heterogeneity by integrating label-free FTIR imaging, laser capture microdissection and proteomics.
- Published in:
- Scientific Reports, 2017, p. 44829, doi. 10.1038/srep44829
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- Publication type:
- Article