Works by Gertsch, Jürg
Results: 63
Cannabimimetic phytochemicals in the diet - an evolutionary link to food selection and metabolic stress adaptation?
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- 2017
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- journal article
Phytocannabinoids beyond the Cannabis plant - do they exist?
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- 2010
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- journal article
Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter.
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- Cell Discovery, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41421-021-00247-4
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- Article
CNS Drug Discovery in Academia: Where Basic Research Meets Innovation.
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- ChemBioChem, 2024, v. 25, n. 19, p. 1, doi. 10.1002/cbic.202400397
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- Article
Structure-Activity Relationships in Side-Chain-Modified Epothilone Analogues-How Important is the Position of the Nitrogen Atom?
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- ChemMedChem, 2006, v. 1, n. 1, p. 37, doi. 10.1002/cmdc.200500051
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- Article
Corrigendum: Catalytic Selective Cyclizations of Aminocyclopropanes: Formal Synthesis of Aspidospermidine and Total Synthesis of Goniomitine.
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- Angewandte Chemie International Edition, 2011, v. 50, n. 18, p. 4038, doi. 10.1002/anie.201190034
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- Article
Inside Cover: Catalytic Selective Cyclizations of Aminocyclopropanes: Formal Synthesis of Aspidospermidine and Total Synthesis of Goniomitine (Angew. Chem. Int. Ed. 33/2010).
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- Angewandte Chemie International Edition, 2010, v. 49, n. 33, p. 5584, doi. 10.1002/anie.201003240
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- Article
Catalytic Selective Cyclizations of Aminocyclopropanes: Formal Synthesis of Aspidospermidine and Total Synthesis of Goniomitine.
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- Angewandte Chemie International Edition, 2010, v. 49, n. 33, p. 5767, doi. 10.1002/anie.201001853
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- Article
Total Synthesis of the Marine Diterpenoid Blumiolide C.
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- Angewandte Chemie International Edition, 2008, v. 47, n. 52, p. 10081, doi. 10.1002/anie.200804004
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- Article
Design and Synthesis of 12-Aza-Epothilones (Azathilones)—“Non-Natural” Natural Products with Potent Anticancer ActivityWe thank Bettina Sager, Jacqueline Loretan, and Robert Reuter for their excellent technical assistance. The Electron Microscopy Centre (EMEZ) of ETH Zürich is acknowledged for excellent technical support.
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- Angewandte Chemie International Edition, 2006, v. 45, n. 35, p. 5880, doi. 10.1002/anie.200601359
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- Article
Cover Picture: Making Epothilones Fluoresce: Design, Synthesis, and Biological Characterization of a Fluorescent N12-Aza-Epothilone (Azathilone) (ChemBioChem 15/2009).
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- ChemBioChem, 2009, v. 10, n. 15, p. 2405, doi. 10.1002/cbic.200990065
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- Article
Making Epothilones Fluoresce: Design, Synthesis, and Biological Characterization of a Fluorescent N12-Aza-Epothilone (Azathilone).
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- ChemBioChem, 2009, v. 10, n. 15, p. 2513, doi. 10.1002/cbic.200900376
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- Article
Differential Effects of Natural Product Microtubule Stabilizers on Microtubule Assembly: Single Agent and Combination Studies with Taxol, Epothilone B, and Discodermolide.
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- ChemBioChem, 2009, v. 10, n. 1, p. 166, doi. 10.1002/cbic.200800556
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- Article
Cannabinoid receptor ligands as potential anticancer agents – high hopes for new therapies?
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- Journal of Pharmacy & Pharmacology, 2009, v. 61, n. 7, p. 839, doi. 10.1211/jpp/61.07.0002
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- Article
Pharmacometabolic Effects of Pteryxin and Valproate on Pentylenetetrazole-Induced Seizures in Zebrafish Reveal Vagus Nerve Stimulation.
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- Cells (2073-4409), 2023, v. 12, n. 11, p. 1540, doi. 10.3390/cells12111540
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- Article
Juniperonic Acid Biosynthesis is Essential in Caenorhabditis elegans Lacking Δ6 Desaturase (fat-3) and Generates New ω-3 Endocannabinoids.
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- Cells (2073-4409), 2020, v. 9, n. 9, p. 2127, doi. 10.3390/cells9092127
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- Article
Evaluating the Effects of Gamma-Irradiation for Decontamination of Medicinal Cannabis.
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- Frontiers in Pharmacology, 2016, p. 1, doi. 10.3389/fphar.2016.00108
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- Article
Mitochondrial CB<sub>1</sub> receptors regulate neuronal energy metabolism.
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- Nature Neuroscience, 2012, v. 15, n. 4, p. 558, doi. 10.1038/nn.3053
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- Article
Opposite physiological and pathological mTORC1-mediated roles of the CB1 receptor in regulating renal tubular function.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29124-8
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- Article
Small molecule inhibitors provide insights into the relevance of LAT1 and LAT2 in materno‐foetal amino acid transport.
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- Journal of Cellular & Molecular Medicine, 2020, v. 24, n. 21, p. 12681, doi. 10.1111/jcmm.15840
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- Article
4'-O-methylhonokiol increases levels of 2-arachidonoyl glycerol in mouse brain via selective inhibition of its COX-2-mediated oxygenation.
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- Journal of Neuroinflammation, 2015, v. 12, n. 1, p. 1, doi. 10.1186/s12974-015-0307-7
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- Article
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes.
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- 2021
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- Publication type:
- journal article
Cytotoxic Steroidal Saponins from the Rhizomes of Tacca integrifolia.
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- Chemistry & Biodiversity, 2010, v. 7, n. 3, p. 610, doi. 10.1002/cbdv.200900042
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- Article
Cultural perception of triatomine bugs and Chagas disease in Bolivia: a cross-sectional field study.
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- Parasites & Vectors, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13071-019-3546-0
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- Article
Synthesis, Profiling, and Bioactive Conformation of trans‐Cyclopropyl Epothilones.
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- Helvetica Chimica Acta, 2019, v. 102, n. 5, p. N.PAG, doi. 10.1002/hlca.201900078
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- Article
Carboxylesterase 1-mediated endocannabinoid metabolism in skin: role in melanoma progression in BRaf<sup>V600E</sup>/Pten<sup>−/−</sup> mice.
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- Cancer & Metabolism, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40170-025-00378-2
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- Article
Neuropsychopharmacological profiling of scoparone in mice.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-04741-3
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- Article
Neuronal oscillations and synchronicity associated with gamma-hydroxybutyrate during resting-state in healthy male volunteers.
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- Psychopharmacology, 2017, v. 234, n. 13, p. 1957, doi. 10.1007/s00213-017-4603-z
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- Article
New Natural Noncannabinoid Ligands for Cannabinoid Type-2 (CB<sub>2</sub>) Receptors.
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- Journal of Receptors & Signal Transduction, 2006, v. 26, n. 5/6, p. 709, doi. 10.1080/10799890600942674
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- Article
Targeted metabolomics shows plasticity in the evolution of signaling lipids and uncovers old and new endocannabinoids in the plant kingdom.
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- Scientific Reports, 2017, p. 41177, doi. 10.1038/srep41177
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- Article
The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2018, v. 37, n. 1, p. N.PAG, doi. 10.1186/s13046-018-0907-z
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- Article
The Evaluation of l‐Tryptophan Derivatives as Inhibitors of the l‐Type Amino Acid Transporter LAT1 (SLC7A5).
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- ChemMedChem, 2022, v. 17, n. 17, p. 1, doi. 10.1002/cmdc.202200308
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- Article
Synthesis and Biological Evaluation of Endocannabinoid Uptake Inhibitors Derived from WOBE437.
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- ChemMedChem, 2021, v. 16, n. 1, p. 145, doi. 10.1002/cmdc.202000153
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- Article
Front Cover: Total Synthesis of the Endocannabinoid Uptake Inhibitor Guineensine and SAR Studies (ChemMedChem 17/2019).
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- ChemMedChem, 2019, v. 14, n. 17, p. 1573, doi. 10.1002/cmdc.201900490
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Total Synthesis of the Endocannabinoid Uptake Inhibitor Guineensine and SAR Studies.
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- ChemMedChem, 2019, v. 14, n. 17, p. 1590, doi. 10.1002/cmdc.201900390
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- Article
A pterocarpan from the seeds of Bituminaria morisiana.
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- Journal of Natural Medicines, 2010, v. 64, n. 3, p. 354, doi. 10.1007/s11418-010-0408-7
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- Article
Elevated Levels of Endocannabinoids in Chronic Hepatitis C May Modulate Cellular Immune Response and Hepatic Stellate Cell Activation.
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- International Journal of Molecular Sciences, 2015, v. 16, n. 4, p. 7057, doi. 10.3390/ijms16047057
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Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones).
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- Molecules, 2016, v. 21, n. 8, p. 1010, doi. 10.3390/molecules21081010
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- Article
Insights into the Phytochemical and Multifunctional Biological Profile of Spices from the Genus Piper.
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- Antioxidants, 2021, v. 10, n. 10, p. 1642, doi. 10.3390/antiox10101642
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- Article
Inhibition of fatty acid amide hydrolase exerts cutaneous anti-inflammatory effects both in vitro and in vivo.
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- Experimental Dermatology, 2016, v. 25, n. 4, p. 328, doi. 10.1111/exd.12930
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- Article
Structural insights into the mechanism and dynamics of proteorhodopsin biogenesis and retinal scavenging.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50960-3
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- Article
Structural insights into the mechanism and dynamics of proteorhodopsin biogenesis and retinal scavenging.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50960-3
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- Article
Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects.
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- Chimia, 2024, v. 78, n. 7/8, p. 499, doi. 10.2533/chimia.2024.499
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Structure, Function and Pharmacology of SLC7 Family Members and Homologues.
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- Chimia, 2022, v. 76, n. 12, p. 1011, doi. 10.2533/chimia.2022.1011
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- Article
Synthesis of Morpholine‐Based Analogues of (−)‐Zampanolide and Their Biological Activity.
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- Chemistry - A European Journal, 2021, v. 27, n. 19, p. 5936, doi. 10.1002/chem.202003996
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- Article
Berichtigung: Catalytic Selective Cyclizations of Aminocyclopropanes: Formal Synthesis of Aspidospermidine and Total Synthesis of Goniomitine.
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- Angewandte Chemie, 2011, v. 123, n. 18, p. 4124, doi. 10.1002/ange.201190035
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- Article
Catalytic Selective Cyclizations of Aminocyclopropanes: Formal Synthesis of Aspidospermidine and Total Synthesis of Goniomitine.
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- Angewandte Chemie, 2010, v. 122, n. 33, p. 5903, doi. 10.1002/ange.201001853
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- Article
Innentitelbild: Catalytic Selective Cyclizations of Aminocyclopropanes: Formal Synthesis of Aspidospermidine and Total Synthesis of Goniomitine (Angew. Chem. 33/2010).
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- Angewandte Chemie, 2010, v. 122, n. 33, p. 5716, doi. 10.1002/ange.201003240
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- Article
Entwurf und Synthese von 12-Aza-Epothilonen (Azathilonen) – “nicht-natürliche Naturstoffe” mit potenter AntitumorwirkungBettina Sager, Jaqueline Loretan und Robert Reuter sei herzlich für die exzellente technische...
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- Angewandte Chemie, 2006, v. 118, n. 35, p. 6013, doi. 10.1002/ange.200601359
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- Article
Pharmacokinetics and pharmacodynamics of γ-hydroxybutyrate in healthy subjects.
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- British Journal of Clinical Pharmacology, 2016, v. 81, n. 5, p. 980, doi. 10.1111/bcp.12863
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- Article