Works matching AU Gertler, Frank B.

Results: 36

Correction: Eps8 Regulates Axonal Filopodia in Hippocampal Neurons in Response to Brain-Derived Neurotrophic Factor (BDNF).

Published in:

2015

By:

Menna, Elisabetta;
Disanza, Andrea;
Cagnoli, Cinzia;
Schenk, Ursula;
Gelsomino, Giuliana;
Frittoli, Emanuela;
Hertzog, Maud;
Offenhauser, Nina;
Sawallisch, Corinna;
Kreienkamp, Hans-Jürgen;
Gertler, Frank B.;
Di Fiore, Pier Paolo;
Scita, Giorgio;
Matteoli, Michela

Publication type:

Correction Notice

Eps8 Regulates Axonal Filopodia in Hippocampal Neurons in Response to Brain-Derived Neurotrophic Factor (BDNF).

Published in:

PLoS Biology, 2009, v. 7, n. 6, p. 1, doi. 10.1371/journal.pbio.1000138

By:

Menna, Elisabetta;
Disanza, Andrea;
Cagnoli, Cinzia;
Schenk, Ursula;
Gelsomino, Giuliana;
Frittoli, Emanuela;
Hertzog, Maud;
Offenhauser, Nina;
Sawallisch, Corinna;
Kreienkamp, Hans-Jürgen;
Gertler, Frank B.;
Di Fiore, Pier Paolo;
Scita, Giorgio;
Matteoli, Michela

Publication type:

Article

Emergence of Large-Scale Cell Morphology and Movement from Local Actin Filament Growth Dynamics.

Published in:

PLoS Biology, 2007, v. 5, n. 9, p. e233, doi. 10.1371/journal.pbio.0050233

By:

Lacayo, Catherine I.;
Pincus, Zachary;
VanDuijn, Martijn M.;
Wilson, Cyrus A.;
Fletcher, Daniel A.;
Gertler, Frank B.;
Mogilner, Alex;
Theriot, Julie A.

Publication type:

Article

A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family.

Published in:

EMBO Journal, 1997, v. 16, n. 17, p. 5433, doi. 10.1093/emboj/16.17.5433

By:

Niebuhr, Kirsten;
Ebel, Frank;
Frank, Ronald;
Reinhard, Matthias;
Domann, Eugen;
Carl, Uwe D.;
Walter, Ulrich;
Gertler, Frank B.;
Wehland, Jürgen;
Chakraborty, Trinad

Publication type:

Article

Mouse disabled (mDab1): a Src binding protein implicated in neuronal development.

Published in:

EMBO Journal, 1997, v. 16, n. 1, p. 121, doi. 10.1093/emboj/16.1.121

By:

Howell, Brian W.;
Gertler, Frank B.;
Cooper, Jonathan A.

Publication type:

Article

Ena/VASP proteins contribute to Listeria monocytogenes pathogenesis by controlling temporal and spatial persistence of bacterial actin-based motility.

Published in:

Molecular Microbiology, 2003, v. 49, n. 5, p. 1361, doi. 10.1046/j.1365-2958.2003.03639.x

By:

Auerbuch, Victoria;
Loureiro, Joseph J.;
Gertler, Frank B.;
Theriot, Julie A.;
Portnoy, Daniel A.

Publication type:

Article

Selectivity in subunit composition of Ena/VASP tetramers.

Published in:

Bioscience Reports, 2015, v. 35, n. 5, p. 1, doi. 10.1042/BSR20150149

By:

Riquelme, Daisy N.;
Meyer, Aaron S.;
Barzik, Melanie;
Keating, Amy;
Gertler, Frank B.

Publication type:

Article

Mena and Vasodilator-Stimulated Phosphoprotein Are Required for Multiple Actin-Dependent Processes That Shape the Vertebrate Nervous System.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 37, p. 8029, doi. 10.1523/JNEUROSCI.1057-04.2004

By:

Menzies, A. Shiela;
Aszodi, Attila;
Williams, Scott E.;
Pfeifer, Alexander;
Wehman, Ann M.;
Keow Lin Goh;
Mason, Carol A.;
Fassler, Reinhard;
Gertler, Frank B.

Publication type:

Article

In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression.

Published in:

Nature Genetics, 2009, v. 41, n. 10, p. 1133, doi. 10.1038/ng.451

By:

Meacham, Corbin E.;
Ho, Emily E.;
Dubrovsky, Esther;
Gertler, Frank B.;
Hemann, Michael T.

Publication type:

Article

Corrigendum: A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference.

Published in:

2007

By:

Rubinson, Douglas A;
Dillon, Christopher P;
Kwiatkowski, Adam V;
Sievers, Claudia;
Yang, Lili;
Kopinja, Johnny;
Zhang, Mingdi;
McManus, Michael T;
Gertler, Frank B;
Scott, Martin L;
Van Parijs, Luk

Publication type:

Correction Notice

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference.

Published in:

Nature Genetics, 2003, v. 33, n. 3, p. 401, doi. 10.1038/ng1117

By:

Rubinson, Douglas A.;
Dillon, Christopher P.;
Kwiatkowski, Adam V.;
Sievers, Claudia;
Yang, Lili;
Kopinja, Johnny;
Zhang, Mingdi;
McManus, Michael T.;
Gertler, Frank B.;
Scott, Martin L.;
Van Parijs, Luk

Publication type:

Article

A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila.

Published in:

Nature Genetics, 2002, v. 30, n. 4, p. 367, doi. 10.1038/ng864

By:

Kazantsev, Aleksey;
Walker, Heli A.;
Slepko, Natalia;
Bear, James E.;
Preisinger, Elizabeth;
Steffan, Joan S.;
Zhu, Ya-Zhen;
Gertler, Frank B.;
Housman, David E.;
Marsh, J. Lawrence;
Thompson, Leslie M.

Publication type:

Article

An EMT--Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype.

Published in:

PLoS Genetics, 2011, v. 7, n. 8, p. 1, doi. 10.1371/journal.pgen.1002218

By:

Shapiro, Irina M.;
Cheng, Albert W.;
Flytzanis, Nicholas C.;
Balsamo, Michele;
Condeelis, John S.;
Oktay, Maja H.;
Burge, Christopher B.;
Gertler, Frank B.

Publication type:

Article

Lamellipodin-Deficient Mice: A Model of Rectal Carcinoma.

Published in:

PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0152940

By:

Miller, Cassandra L.;
Muthupalani, Sureshkumar;
Shen, Zeli;
Drees, Frauke;
Ge, Zhongming;
Feng, Yan;
Chen, Xiaowei;
Gong, Guanyu;
Nagar, Karan K.;
Wang, Timothy C.;
Gertler, Frank B.;
Fox, James G.

Publication type:

Article

αvβ3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration.

Published in:

Journal of Cell Biology, 2010, v. 189, n. 2, p. 369, doi. 10.1083/jcb.200912014

By:

Worth, Daniel C.;
Hodivala-Dilke, Kairbaan;
Robinson, Stephen D.;
King, Samantha J.;
Morton, Penny E.;
Gertler, Frank B.;
Humphries, Martin J.;
Parsons, Maddy

Publication type:

Article

Ena/VASP is required for endothelial barrier function in vivo.

Published in:

Journal of Cell Biology, 2007, v. 179, n. 4, p. 761, doi. 10.1083/jcb.200705002

By:

Furman, Craig;
Sieminski, Alisha L.;
Kwiatkowski, Adam V.;
Rubinson, Douglas A.;
Vasile, Eliza;
Bronson, Roderick T.;
Fässler, Reinhard;
Gertler, Frank B.

Publication type:

Article

Shigella interactions with the actin cytoskeleton in the absence of Ena/VASP family proteins.

Published in:

Cellular Microbiology, 2004, v. 6, n. 4, p. 355, doi. 10.1046/j.1462-5822.2003.00359.x

By:

Ally, Shabeen;
Sauer, Noel J.;
Loureiro, Joseph J.;
Snapper, Scott B.;
Gertler, Frank B.;
Goldberg, Marcia B.

Publication type:

Article

Mechanosensing during directed cell migration requires dynamic actin polymerization at focal adhesions.

Published in:

Journal of Cell Biology, 2019, v. 218, n. 12, p. 4215, doi. 10.1083/jcb.201902101

By:

Puleo, Julieann I.;
Parker, Sara S.;
Roman, Mackenzie R.;
Watson, Adam W.;
Eliato, Kiarash Rahmani;
Leilei Peng;
Saboda, Kathylynn;
Roe, Denise J.;
Ros, Robert;
Gertler, Frank B.;
Mouneimne, Ghassan

Publication type:

Article

5'-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion.

Published in:

Journal of Cell Biology, 2016, v. 214, n. 6, p. 719, doi. 10.1083/jcb.201501003

By:

Rajadurai, Charles V.;
Havrylov, Serhiy;
Coelho, Paula P.;
Ratcliffe, Colin D. H.;
Zaoui, Kossay;
Huang, Bruce H.;
Monast, Anie;
Chughtai, Naila;
Sangwan, Veena;
Gertler, Frank B.;
Siegel, Peter M.;
Park, Morag

Publication type:

Article

A requirement for filopodia extension toward Slit during Robo-mediated axon repulsion.

Published in:

Journal of Cell Biology, 2016, v. 213, n. 2, p. 261, doi. 10.1083/jcb.201509062

By:

McConnell, Russell E.;
van Veen, J. Edward;
Vidaki, Marina;
Kwiatkowski, Adam V.;
Meyer, Aaron S.;
Gertler, Frank B.

Publication type:

Article

Mena binds α5 integrin directly and modulates α5β1 function.

Published in:

Journal of Cell Biology, 2012, v. 198, n. 4, p. 657, doi. 10.1083/jcb.201202079

By:

Gupton, Stephanie L.;
Riquelme, Daisy;
Hughes-Alford, Shannon K.;
Tadros, Jenny;
Rudina, Shireen S.;
Hynes, Richard O.;
Lauffenburger, Douglas;
Gertler, Frank B.

Publication type:

Article

2D protrusion but not motility predicts growth factor-induced cancer cell migration in 3D collagen.

Published in:

Journal of Cell Biology, 2012, v. 197, n. 6, p. 721, doi. 10.1083/jcb.201201003

By:

Meyer, Aaron S.;
Hughes-Alford, Shannon K.;
Kay, Jennifer E.;
Castillo, Amalchi;
Wells, Alan;
Gertler, Frank B.;
Lauffenburged, Douglas A.

Publication type:

Article

The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics.

Published in:

Journal of Cell Biology, 2010, v. 190, n. 3, p. 307, doi. 10.1083/jcb.201005018

By:

Nakatsu, Fubito;
Perera, Rushika M.;
Lucast, Louise;
Zoncu, Roberto;
Domin, Jan;
Gertler, Frank B.;
Toomre, Derek;
De Camilli, Pietro

Publication type:

Article

Quantitative assessment of invasive mena isoforms (Mena<sup>calc</sup>) as an independent prognostic marker in breast cancer.

Published in:

Breast Cancer Research, 2012, v. 14, n. 5, p. 3318, doi. 10.1186/bcr3318

By:

Agarwal, Seema;
Gertler, Frank B.;
Balsamo, Michele;
Condeelis, John S.;
Camp, Robert L.;
Xiaonan Xue;
Juan Lin;
Rohan, Thomas E.;
Rimm, David L.

Publication type:

Article

Quantitative assessment of invasive mena isoforms (Menacalc) as an independent prognostic marker in breast cancer.

Published in:

2012

By:

Agarwal, Seema;
Gertler, Frank B;
Balsamo, Michele;
Condeelis, John S;
Camp, Robert L;
Xue, Xiaonan;
Lin, Juan;
Rohan, Thomas E;
Rimm, David L

Publication type:

journal article

Lpd depletion reveals that SRF specifies radial versus tangential migration of pyramidal neurons.

Published in:

Nature Cell Biology, 2011, v. 13, n. 8, p. 989, doi. 10.1038/ncb2292

By:

Pinheiro, Elaine M.;
Xie, Zhigang;
Norovich, Amy L.;
Vidaki, Marina;
Tsai, Li-Huei;
Gertler, Frank B.

Publication type:

Article

Filopodia are required for cortical neurite initiation.

Published in:

Nature Cell Biology, 2007, v. 9, n. 12, p. 1347, doi. 10.1038/ncb1654

By:

Dent, Erik W.;
Kwiatkowski, Adam V.;
Mebane, Leslie M.;
Philippar, Ulrike;
Barzik, Melanie;
Rubinson, Douglas A.;
Gupton, Stephanie;
Van Veen, J. Edward;
Furman, Craig;
Zhang, Jiangyang;
Alberts, Arthur S.;
Mori, Susumu;
Gertler, Frank B.

Publication type:

Article

Time series modeling of live-cell shape dynamics for image-based phenotypic profiling.

Published in:

Integrative Biology, 2016, v. 8, n. 1, p. 73, doi. 10.1039/c5ib00283d

By:

Gordonov, Simon;
Hwang, Mun Kyung;
Wells, Alan;
Gertler, Frank B.;
Lauffenburger, Douglas A.;
Bathe, Mark

Publication type:

Article

Peptide Array X-Linking (PAX): A New Peptide-Protein Identification Approach.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037035

By:

Okada, Hirokazu;
Uezu, Akiyoshi;
Soderblom, Erik J.;
Moseley, III., M. Arthur;
Gertler, Frank B.;
Soderling, Scott H.

Publication type:

Article

Tumor Microenvironment of Metastasis and Risk of Distant Metastasis of Breast Cancer.

Published in:

JNCI: Journal of the National Cancer Institute, 2014, v. 106, n. 8, p. 1, doi. 10.1093/jnci/dju136

By:

Rohan, Thomas E.;
Xue, Xiaonan;
Lin, Hung-Mo;
D’Alfonso, Timothy M.;
Ginter, Paula S.;
Oktay, Maja H.;
Robinson, Brian D.;
Ginsberg, Mindy;
Gertler, Frank B.;
Glass, Andrew G.;
Sparano, Joseph A.;
Condeelis, John S.;
Jones, Joan G.

Publication type:

Article

Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway.

Published in:

eLife, 2015, p. 1, doi. 10.7554/eLife.04953

By:

Irvine, Darrell J.;
Dustin, Michael L.;
Kumari, Sudha;
Depoil, David;
Burkhardt, Janis K.;
Carmona, Guillaume;
Gertler, Frank B.;
Carman, Christopher V.;
Martinelli, Roberta;
Judokusumo, Edward;
Kam, Lance C.

Publication type:

Article

Invasive breast carcinoma cells from patients exhibit Mena<sup>INV</sup>- and macrophage-dependent transendothelial migration.

Published in:

Science Signaling, 2014, v. 7, n. 353, p. 1, doi. 10.1126/scisignal.2005438

By:

Pignatelli, Jeanine;
Goswami, Sumanta;
Jones, Joan G.;
Rohan, Thomas E.;
Pieri, Evan;
Chen, Xiaoming;
Adler, Esther;
Cox, Dianne;
Maleki, Sara;
Bresnick, Anne;
Gertler, Frank B.;
Condeelis, John S.;
Oktay, Maja H.

Publication type:

Article

The Receptor AXL Diversifies EGFR Signaling and Limits the Response to EGFR-Targeted Inhibitors in Triple-Negative Breast Cancer Cells.

Published in:

Science Signaling, 2013, v. 6, n. 287, p. 1, doi. 10.1126/scisignal.2004155

By:

Meyer, Aaron S.;
Miller, Miles A.;
Gertler, Frank B.;
Lauffenburger, Douglas A.

Publication type:

Article

The Murine Nck SH2/SH3 Adaptors Are Important for the Development of Mesoderm-Derived Embryonic Structures and for Regulating the Cellular Actin Network.

Published in:

Molecular & Cellular Biology, 2003, v. 23, n. 13, p. 4586, doi. 10.1128/MCB.23.13.4586-4597.2003

By:

Bladt, Friedhelm;
Aippersbach, Elke;
Gelkop, Sigal;
Strasser, Geraldine A.;
Nash, Piers;
Tafuri, Anna;
Gertler, Frank B.;
Pawson, Tony

Publication type:

Article

Targeted Disruption of the Murine zyxin Gene.

Published in:

Molecular & Cellular Biology, 2003, v. 23, n. 1, p. 70, doi. 10.1128/MCB.23.1.70-79.2003

By:

Hoffman, Laura M.;
Nix, David A.;
Benson, Beverly;
Boot-Hanford, Ray;
Gustafsson, Erika;
Jamora, Colin;
Menzies, A. Sheila;
Keow Lin Goh;
Jensen, Christopher C.;
Gertler, Frank B.;
Fuchs, Elaine;
Fässler, Reinhard;
Beckerle, Mary C.

Publication type:

Article

The alternatively-included 11a sequence modifies the effects of Mena on actin cytoskeletal organization and cell behavior.

Published in:

Scientific Reports, 2016, p. 35298, doi. 10.1038/srep35298

By:

Balsamo, Michele;
Mondal, Chandrani;
Carmona, Guillaume;
McClain, Leslie M.;
Riquelme, Daisy N.;
Tadros, Jenny;
Ma, Duan;
Vasile, Eliza;
Condeelis, John S.;
Lauffenburger, Douglas A.;
Gertler, Frank B.

Publication type:

Article