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Adaptation to chronic ER stress enforces pancreatic β-cell plasticity.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32425-7
By:
- Chen, Chien-Wen;
- Guan, Bo-Jhih;
- Alzahrani, Mohammed R.;
- Gao, Zhaofeng;
- Gao, Long;
- Bracey, Syrena;
- Wu, Jing;
- Mbow, Cheikh A.;
- Jobava, Raul;
- Haataja, Leena;
- Zalavadia, Ajay H.;
- Schaffer, Ashleigh E.;
- Lee, Hugo;
- LaFramboise, Thomas;
- Bederman, Ilya;
- Arvan, Peter;
- Mathews, Clayton E.;
- Gerling, Ivan C.;
- Kaestner, Klaus H.;
- Tirosh, Boaz
Publication type:
Article
Functional characterization of two-dimensional gel-separated proteins using sequential staining.
Published in:
Electrophoresis, 2005, v. 26, n. 1, p. 225, doi. 10.1002/elps.200406176
By:
- Jian Wu;
- Nataliya J. Lenchik;
- Michael J. Pabst;
- Solomon S. Solomon;
- James Shull;
- Ivan C. Gerling
Publication type:
Article
The IGFBP3/TMEM219 pathway regulates beta cell homeostasis.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28360-2
By:
- D'Addio, Francesca;
- Maestroni, Anna;
- Assi, Emma;
- Ben Nasr, Moufida;
- Amabile, Giovanni;
- Usuelli, Vera;
- Loretelli, Cristian;
- Bertuzzi, Federico;
- Antonioli, Barbara;
- Cardarelli, Francesco;
- El Essawy, Basset;
- Solini, Anna;
- Gerling, Ivan C.;
- Bianchi, Cristina;
- Becchi, Gabriella;
- Mazzucchelli, Serena;
- Corradi, Domenico;
- Fadini, Gian Paolo;
- Foschi, Diego;
- Markmann, James F.
Publication type:
Article
Genetic predisposition in the 2′-5′A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity.
Published in:
Diabetologia, 2021, v. 64, n. 8, p. 1805, doi. 10.1007/s00125-021-05469-5
By:
- Pedersen, Kristina;
- Haupt-Jorgensen, Martin;
- Krogvold, Lars;
- Kaur, Simranjeet;
- Gerling, Ivan C.;
- Pociot, Flemming;
- Dahl-Jørgensen, Knut;
- Buschard, Karsten
Publication type:
Article
Abnormal islet sphingolipid metabolism in type 1 diabetes.
Published in:
Diabetologia, 2018, v. 61, n. 7, p. 1650, doi. 10.1007/s00125-018-4614-2
By:
- Holm, Laurits J.;
- Krogvold, Lars;
- Hasselby, Jane P.;
- Kaur, Simranjeet;
- Claessens, Laura A.;
- Russell, Mark A.;
- Mathews, Clayton E.;
- Hanssen, Kristian F.;
- Morgan, Noel G.;
- Koeleman, Bobby P. C.;
- Roep, Bart O.;
- Gerling, Ivan C.;
- Pociot, Flemming;
- Dahl-Jørgensen, Knut;
- Buschard, Karsten
Publication type:
Article
Molecular Phenotyping of Immune Cells from Young NOD Mice Reveals Abnormal Metabolic Pathways in the Early Induction Phase of Autoimmune Diabetes.
Published in:
PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046941
By:
- Wu, Jian;
- Kakoola, Dorothy N.;
- Lenchik, Nataliya I.;
- Desiderio, Dominic M.;
- Marshall, Dana R.;
- Gerling, Ivan C.
Publication type:
Article
From aldosteronism to oxidative stress: the role of excessive intracellular calcium accumulation.
Published in:
Hypertension Research, 2010, v. 33, n. 11, p. 1091, doi. 10.1038/hr.2010.159
By:
- Zia, Ayhan A;
- Kamalov, German;
- Newman, Kevin P;
- McGee, Jesse E;
- Bhattacharya, Syamal K;
- Ahokas, Robert A;
- Sun, Yao;
- Gerling, Ivan C;
- Weber, Karl T
Publication type:
Article
Proteome of monocytes primed with lipopolysaccharide: Analysis of the abundant proteins.
Published in:
Proteomics, 2003, v. 3, n. 9, p. 1767, doi. 10.1002/pmic.200300532
By:
- Himanshu S. Gadgil;
- Karen M. Pabst;
- Francesco Giorgianni;
- Edward S. Umstot;
- Dominic M. Desiderio;
- Sarka Beranova-Giorgianni;
- Ivan C. Gerling
Publication type:
Article
Oxidative stress in aldosteronism
Published in:
Cardiovascular Research, 2006, v. 71, n. 2, p. 300, doi. 10.1016/j.cardiores.2006.03.007
By:
- Sun, Yao;
- Ahokas, Robert A.;
- Bhattacharya, Syamal K.;
- Gerling, Ivan C.;
- Carbone, Laura D.;
- Weber, Karl T.
Publication type:
Article
Toward a broader understanding of aldosterone in congestive heart failure.
Published in:
Journal of the Renin-Angiotensin-Aldosterone System, 2003, v. 4, n. 3, p. 155, doi. 10.3317/jraas.2003.024
By:
- Weber, Karl T;
- Yao Sun;
- Wodi, Linus A;
- Munir, Ahmad;
- Jahangir, Eiman;
- Ahokas, Robert A;
- Gerling, Ivan C;
- Postlethwaite, Arnold E;
- Warrington, Kenneth J
Publication type:
Article
Approaches to reduce false positives and false negatives in the analysis of microarray data: applications in type 1 diabetes research.
Published in:
BMC Genomics, 2008, v. 9, p. 1, doi. 10.1186/1471-2164-9-S2-S12
By:
- Jian Wu;
- Lenchik, Nataliya I.;
- Gerling, Ivan C.
Publication type:
Article
Transcriptional profiling of CD4 T-lymphocytes reveals abnormal gene expression in young prediabetic NOD mice.
Published in:
2009
By:
- Kakoola, Dorothy N.;
- Lenchik, Nataliya I.;
- Curcio-Brint, Anita;
- Gerling, Ivan C.
Publication type:
Abstract
Analysis of the transcriptome of CD4 T-Lymphocytes from young Non-Obese Diabetic (NOD) mice suggests a key role for cytokines and apoptosis.
Published in:
BMC Bioinformatics, 2008, v. 9, p. 1, doi. 10.1186/1471-2105-9-S7-P16
By:
- Kakoola, Dorothy N.;
- Lenchik, Nataliya I.;
- Curcio-Brint, Anita;
- Gerling, Ivan C.
Publication type:
Article
Regression of Established Cardiac Fibrosis in Hypertensive Heart Disease.
Published in:
American Journal of Hypertension, 2017, v. 30, n. 11, p. 1049, doi. 10.1093/ajh/hpx054
By:
- Weber, Karl T.;
- Yao Sun;
- Gerling, Ivan C.;
- Guntaka, Ramareddy V.
Publication type:
Article
Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages.
Published in:
2017
By:
- Waqas, Syed F Hassnain;
- Hoang, Anh Cuong;
- Lin, Ya-Tin;
- Ampem, Grace;
- Azegrouz, Hind;
- Balogh, Lajos;
- Thuróczy, Julianna;
- Chen, Jin-Chung;
- Gerling, Ivan C;
- Nam, Sorim;
- Lim, Jong-Seok;
- Martinez-Ibañez, Juncal;
- Real, José T;
- Paschke, Stephan;
- Quillet, Raphaëlle;
- Ayachi, Safia;
- Simonin, Frédéric;
- Schneider, E Marion;
- Brinkman, Jacqueline A;
- Lamming, Dudley W
Publication type:
journal article
Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages.
Published in:
2017
By:
- Waqas, Syed F. Hassnain;
- Anh Cuong Hoang;
- Ya-Tin Lin;
- Ampem, Grace;
- Azegrouz, Hind;
- Balogh, Lajos;
- Thuróczy, Julianna;
- Jin-Chung Chen;
- Gerling, Ivan C.;
- Sorim Nam;
- Jong-Seok Lim;
- Martinez-Ibañez, Juncal;
- Real, José T.;
- Paschke, Stephan;
- Quillet, Raphaëlle;
- Ayachi, Safia;
- Simonin, Frédéric;
- Schneider, E. Marion;
- Brinkman, Jacqueline A.;
- Lamming, Dudley W.
Publication type:
journal article
Islet sympathetic innervation and islet neuropathology in patients with type 1 diabetes.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-85659-8
By:
- Campbell-Thompson, Martha;
- Butterworth, Elizabeth A.;
- Boatwright, J. Lucas;
- Nair, Malavika A.;
- Nasif, Lith H.;
- Nasif, Kamal;
- Revell, Andy Y.;
- Riva, Alberto;
- Mathews, Clayton E.;
- Gerling, Ivan C.;
- Schatz, Desmond A.;
- Atkinson, Mark A.
Publication type:
Article
Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis.
Published in:
PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0145323
By:
- Iannaccone, Alessandro;
- Giorgianni, Francesco;
- New, David D.;
- Hollingsworth, T. J.;
- Umfress, Allison;
- Alhatem, Albert H.;
- Neeli, Indira;
- Lenchik, Nataliya I.;
- Jennings, Barbara J.;
- Calzada, Jorge I.;
- Satterfield, Suzanne;
- Mathews, Dennis;
- Diaz, Rocio I.;
- Harris, Tamara;
- Johnson, Karen C.;
- Charles, Steve;
- Kritchevsky, Stephen B.;
- Gerling, Ivan C.;
- Beranova-Giorgianni, Sarka;
- Radic, Marko Z.
Publication type:
Article
New Insights into Autoimmune Diabetes in Mice from Proteomics and Genomics Studies.
Published in:
Diabetes, 2007, v. 56, p. A643
By:
- Gerling, Ivan C.;
- Lenchik, Nataliya I.;
- Wu, Jian
Publication type:
Article
Retardation or acceleration of diabetes in NOD/Lt mice mediated by intrathymic administration of candidate beta-cell antigens.
Published in:
1997
By:
- Cetkovic-Cvrlje, Marina;
- Gerling, Ivan C.;
- Muir, Andrew;
- Atkinson, Mark A.;
- Elliott, John F.;
- Leiter, Edward H.;
- Cetkovic-Cvrlje, M;
- Gerling, I C;
- Muir, A;
- Atkinson, M A;
- Elliott, J F;
- Leiter, E H
Publication type:
journal article
The Role of Enteroviral Infections in the Development of IDDM.
Published in:
Diabetes, 1997, v. 46, n. 2, p. 161, doi. 10.2337/diab.46.2.161
By:
- Graves, Patricia M.;
- Norris, Jill M.;
- Pallansch, Mark A.;
- Gerling, Ivan C.;
- Rewers, Marian
Publication type:
Article
Multiple low-dose streptozocin-induced diabetes in NOD-scid/scid mice in the absence of functional lymphocytes.
Published in:
1994
By:
- Gerling, Ivan C.;
- Friedman, Harley;
- Greiner, Dale L.;
- Shultz, Leonard D.;
- Leiter, Edward H.;
- Gerling, I C;
- Friedman, H;
- Greiner, D L;
- Shultz, L D;
- Leiter, E H
Publication type:
journal article
Intrathymic Islet Cell Transplantation Reduces β-Cell Autoimmunity and Prevents Diabetes in NOD/Lt Mice.
Published in:
Diabetes, 1992, v. 41, n. 12, p. 1672, doi. 10.2337/diab.41.12.1672
By:
- Gerling, Ivan C.;
- Serreze, David V.;
- Christianson, Sherri W.;
- Leiter, Edward H.
Publication type:
Article
Type 1 diabetes could begin with alterations in innate anti‐viral immunity, which are already at this stage associated with HLA risk haplotypes.
Published in:
Diabetes/Metabolism Research & Reviews, 2023, v. 39, n. 7, p. 1, doi. 10.1002/dmrr.3678
By:
- Buschard, Karsten;
- Jensen, Mathias Høj;
- Krogvold, Lars;
- Gerling, Ivan C.;
- Dahl‐Jørgensen, Knut;
- Pedersen, Kristina;
- Haupt‐Jorgensen, Martin
Publication type:
Article
MENTOR, COLLABORATOR, AND FRIEND.
Published in:
Mass Spectrometry Reviews, 2020, v. 39, n. 5/6, p. 452, doi. 10.1002/mas.21610
By:
- Gerling, Ivan C.
Publication type:
Article
Pancreas Whole Tissue Transcriptomics Highlights the Role of the Exocrine Pancreas in Patients With Recently Diagnosed Type 1 Diabetes.
Published in:
Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.861985
By:
- Välikangas, Tommi;
- Lietzén, Niina;
- Jaakkola, Maria K.;
- Krogvold, Lars;
- Eike, Morten C.;
- Kallionpää, Henna;
- Tuomela, Soile;
- Mathews, Clayton;
- Gerling, Ivan C.;
- Oikarinen, Sami;
- Hyöty, Heikki;
- Dahl-Jorgensen, Knut;
- Elo, Laura L.;
- Lahesmaa, Riitta
Publication type:
Article
Atrophied cardiomyocytes and their potential for rescue and recovery of ventricular function.
Published in:
2016
By:
- Heckle, Mark;
- Flatt, David;
- Sun, Yao;
- Mancarella, Salvatore;
- Marion, Tony;
- Gerling, Ivan;
- Weber, Karl;
- Heckle, Mark R;
- Flatt, David M;
- Marion, Tony N;
- Gerling, Ivan C;
- Weber, Karl T
Publication type:
journal article
Hepatic Gene Expression in Morbidly Obese Women: Implications for Disease Susceptibility.
Published in:
Obesity (19307381), 2009, v. 17, n. 8, p. 1563, doi. 10.1038/oby.2009.49
By:
- Elam, Marshall B.;
- Cowan Jr, George S.;
- Rooney, Robert J.;
- Hiler, M. Lloyd;
- Yellaturu, Chandrahasa R.;
- Xiong Deng;
- Howell, George E.;
- Park, Edwards A.;
- Gerling, Ivan C.;
- Patel, Divyan;
- Corton, J. Christopher;
- Cagen, Lauren M.;
- Wilcox, Henry G.;
- Gandhi, Malay;
- Bahr, Micheal H.;
- Allan, Micheal C.;
- Wodi, Linus A.;
- Cook, George A.;
- Hughes, Thomas A.;
- Raghow, Rajendra
Publication type:
Article
Comparative quantitative proteomic analysis of disease stratified laser captured microdissected human islets identifies proteins and pathways potentially related to type 1 diabetes.
Published in:
PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0183908
By:
- Nyalwidhe, Julius O.;
- Grzesik, Wojciech J.;
- Burch, Tanya C.;
- Semeraro, Michele L.;
- Waseem, Tayab;
- Gerling, Ivan C.;
- Mirmira, Raghavendra G.;
- Morris, Margaret A.;
- Nadler, Jerry L.
Publication type:
Article
Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expression following statin re-challenge.
Published in:
PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0181308
By:
- Elam, Marshall B.;
- Majumdar, Gipsy;
- Mozhui, Khyobeni;
- Gerling, Ivan C.;
- Vera, Santiago R.;
- Fish-Trotter, Hannah;
- Williams, Robert W.;
- Childress, Richard D.;
- Raghow, Rajendra
Publication type:
Article
Erratum. NKG2D Signaling Within the Pancreatic Islets Reduces NOD Diabetes and Increases Protective Central Memory CD8<sup>+</sup> T-Cell Numbers. Diabetes 2020;69:1749-1762.
Published in:
2021
By:
- Trembath, Andrew P.;
- Krausz, Kelsey L.;
- Sharma, Neekun;
- Gerling, Ivan C.;
- Mathews, Clayton E.;
- Markiewicz, Mary A.
Publication type:
journal article
NKG2D Signaling Within the Pancreatic Islets Reduces NOD Diabetes and Increases Protective Central Memory CD8<sup>+</sup> T-Cell Numbers.
Published in:
2020
By:
- Trembath, Andrew P.;
- Krausz, Kelsey L.;
- Sharma, Neekun;
- Gerling, Ivan C.;
- Mathews, Clayton E.;
- Markiewicz, Mary A.
Publication type:
journal article
252-LB: Insulin Secretion Pathway Genes Correlate with Markers Associated with Viral Infections in Human Islets.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-252-LB
By:
- NELSON, GRACE;
- LENCHIK, NATALIYA I.;
- RODRIGUEZ-CALVO, TERESA;
- BALCACEAN, DIANA;
- GERLING, IVAN C.
Publication type:
Article
201-LB: NKG2D Signaling within Pancreatic Islets Reduces NOD Diabetes and Is Associated with CD8+ Central Memory T-Cell Generation.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-201-LB
By:
- TREMBATH, ANDREW;
- SHARMA, NEEKUN;
- GERLING, IVAN C.;
- MATHEWS, CLAYTON E.;
- MARKIEWICZ, MARY A.
Publication type:
Article
93-OR: Expression of Genes Associated with Host Viral Responses in Insulitic Islets.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-93-OR
By:
- NELSON, GRACE;
- LENCHIK, NATALIYA I.;
- CAMPBELL-THOMPSON, MARTHA;
- MATHEWS, CLAYTON E.;
- ATKINSON, MARK A.;
- GERLING, IVAN C.
Publication type:
Article

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