Works by Gerlach, Roman G.

Results: 31

Increased zinc levels facilitate phenotypic detection of ceftazidime-avibactam resistance in metallo-β-lactamase-producing Gram-negative bacteria.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.977330

By:

Simon, Michaela;
Gerlach, Roman G.;
Pfeifer, Yvonne;
Pfennigwerth, Niels;
Gatermann, Sören G.;
Schröder, Agnes;
Hiergeist, Andreas;
Hamprecht, Axel;
Rügamer, Tamara;
Gessner, André;
Jantsch, Jonathan

Publication type:

Article

Enhanced invasion and survival of antibiotic- resistant Klebsiella pneumoniae pathotypes in host cells and strain-specific replication in blood.

Published in:

Frontiers in Cellular & Infection Microbiology, 2025, p. 1, doi. 10.3389/fcimb.2025.1522573

By:

Klaper, Kathleen;
Pfeifer, Yvonne;
Heinrich, Lena;
Prax, Marcel;
Krut, Oleg;
Bekeredjian-Ding, Isabelle;
Wahl, Anika;
Fischer, Martin A.;
Kaspar, Heike;
Borgmann, Stefan;
Gerlach, Roman G.;
Werner, Guido

Publication type:

Article

O2-dependent incapacitation of the Salmonella pathogenicity island 1 repressor HilE.

Published in:

Frontiers in Cellular & Infection Microbiology, 2025, p. 1, doi. 10.3389/fcimb.2025.1434254

By:

Walter, Steffi;
Schatz, Valentin;
Petzold, Jana;
Schmidt, Christiane;
Hoffmann, Stefanie;
Jantsch, Jonathan;
Gerlach, Roman G.

Publication type:

Article

Subversion of a family of antimicrobial proteins by Salmonella enterica.

Published in:

Frontiers in Cellular & Infection Microbiology, 2024, p. 1, doi. 10.3389/fcimb.2024.1375887

By:

Gerlach, Roman G.;
Wittmann, Irene;
Heinrich, Lena;
Pinkenburg, Olaf;
Meyer, Torben;
Elpers, Laura;
Schmidt, Christiane;
Hensel, Michael;
Schnare, Markus

Publication type:

Article

Inflammation Fuels Colicin Ib-Dependent Competition of Salmonella Serovar Typhimurium and E. coli in Enterobacterial Blooms.

Published in:

PLoS Pathogens, 2014, v. 10, n. 1, p. 1, doi. 10.1371/journal.ppat.1003844

By:

Nedialkova, Lubov Petkova;
Denzler, Rémy;
Koeppel, Martin B.;
Diehl, Manuel;
Ring, Diana;
Wille, Thorsten;
Gerlach, Roman G.;
Stecher, Bärbel

Publication type:

Article

Low-oxygen tensions found in S almonella-infected gut tissue boost S almonella replication in macrophages by impairing antimicrobial activity and augmenting S almonella virulence.

Published in:

Cellular Microbiology, 2015, v. 17, n. 12, p. 1833, doi. 10.1111/cmi.12476

By:

Jennewein, Jonas;
Matuszak, Jasmin;
Walter, Steffi;
Felmy, Boas;
Gendera, Kathrin;
Schatz, Valentin;
Nowottny, Monika;
Liebsch, Gregor;
Hensel, Michael;
Hardt, Wolf‐Dietrich;
Gerlach, Roman G.;
Jantsch, Jonathan

Publication type:

Article

The S almonella enterica giant adhesin SiiE binds to polarized epithelial cells in a lectin-like manner.

Published in:

Cellular Microbiology, 2014, v. 16, n. 6, p. 962, doi. 10.1111/cmi.12253

By:

Wagner, Carolin;
Barlag, Britta;
Gerlach, Roman G.;
Deiwick, Jörg;
Hensel, Michael

Publication type:

Article

SiiA and SiiB are novel type I secretion system subunits controlling SPI4-mediated adhesion of S almonella enterica.

Published in:

Cellular Microbiology, 2014, v. 16, n. 2, p. 161, doi. 10.1111/cmi.12222

By:

Wille, Thorsten;
Wagner, Carolin;
Mittelstädt, Wilrun;
Blank, Kathrin;
Sommer, Erik;
Malengo, Gabriele;
Döhler, Daniela;
Lange, Anna;
Sourjik, Viktor;
Hensel, Michael;
Gerlach, Roman G.

Publication type:

Article

Functional dissection of SiiE, a giant non-fimbrial adhesin of Salmonella enterica.

Published in:

Cellular Microbiology, 2011, v. 13, n. 8, p. 1286, doi. 10.1111/j.1462-5822.2011.01621.x

By:

Wagner, Carolin;
Polke, Melanie;
Gerlach, Roman G.;
Linke, Dirk;
Stierhof, York-Dieter;
Schwarz, Heinz;
Hensel, Michael

Publication type:

Article

Cooperation of Salmonella pathogenicity islands 1 and 4 is required to breach epithelial barriers.

Published in:

Cellular Microbiology, 2008, v. 10, n. 11, p. 2364, doi. 10.1111/j.1462-5822.2008.01218.x

By:

Gerlach, Roman G.;
Cláudio, Nuno;
Rohde, Manfred;
Jäckel, Daniela;
Wagner, Carolin;
Hensel, Michael

Publication type:

Article

Salmonella Pathogenicity Island 4 encodes a giant non-fimbrial adhesin and the cognate type 1 secretion system.

Published in:

Cellular Microbiology, 2007, v. 9, n. 7, p. 1834, doi. 10.1111/j.1462-5822.2007.00919.x

By:

Gerlach, Roman G.;
Jäckel, Daniela;
Stecher, Bärbel;
Wagner, Carolin;
Lupas, Andrei;
Hardt, Wolf-Dietrich;
Hensel, Michael

Publication type:

Article

Scalable Reporter Assays to Analyze the Regulation of stx2 Expression in Shiga Toxin-Producing Enteropathogens.

Published in:

Toxins, 2021, v. 13, n. 8, p. 534, doi. 10.3390/toxins13080534

By:

Koeppel, Martin B.;
Glaser, Jana;
Baumgartner, Tobias;
Spriewald, Stefanie;
Gerlach, Roman G.;
von Armansperg, Benedikt;
Leong, John M.;
Stecher, Bärbel

Publication type:

Article

A Gateway-Based System for Fast Evaluation of Protein-Protein Interactions in Bacteria.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0123646

By:

Wille, Thorsten;
Barlag, Britta;
Jakovljevic, Vladimir;
Hensel, Michael;
Sourjik, Victor;
Gerlach, Roman G.

Publication type:

Article

LPS Structure and PhoQ Activity Are Important for Salmonella Typhimurium Virulence in the Gallleria mellonella Infection Model.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0073287

By:

Bender, Jennifer K.;
Wille, Thorsten;
Blank, Kathrin;
Lange, Anna;
Gerlach, Roman G.

Publication type:

Article

Rapid and Highly Efficient Method for Scarless Mutagenesis within the Salmonella enterica Chromosome.

Published in:

PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0015763

By:

Blank, Kathrin;
Hensel, Michael;
Gerlach, Roman G.

Publication type:

Article

Corynebacterium diphtheriae invasion-associated protein (DIP1281) is involved in cell surface organization, adhesion and internalization in epithelial cells.

Published in:

BMC Microbiology, 2010, v. 10, p. 1, doi. 10.1186/1471-2180-10-2

By:

Ott, Lisa;
Höller, Martina;
Gerlach, Roman G;
Hensel, Michael;
Rheinlaender, Johannes;
Schäffer, Tilman E;
Burkovski, Andreas

Publication type:

Article

Temperate phages promote colicin-dependent fitness of S almonella enterica serovar Typhimurium.

Published in:

Environmental Microbiology, 2016, v. 18, n. 5, p. 1591, doi. 10.1111/1462-2920.13077

By:

Nedialkova, Lubov P.;
Sidstedt, Maja;
Koeppel, Martin B.;
Spriewald, Stefanie;
Ring, Diana;
Gerlach, Roman G.;
Bossi, Lionello;
Stecher, Bärbel

Publication type:

Article

L-arginine metabolism as pivotal interface of mutual host–microbe interactions in the gut.

Published in:

Gut Microbes, 2023, v. 15, n. 1, p. 1, doi. 10.1080/19490976.2023.2222961

By:

Nüse, Björn;
Holland, Tim;
Rauh, Manfred;
Gerlach, Roman G.;
Mattner, Jochen

Publication type:

Article

Orofacial clefts alter early life oral microbiome maturation towards higher levels of potentially pathogenic species: A prospective observational study.

Published in:

Journal of Oral Microbiology, 2023, v. 15, n. 1, p. 1, doi. 10.1080/20002297.2022.2164147

By:

Seidel, Corinna L.;
Strobel, Karin;
Weider, Matthias;
Tschaftari, Marco;
Unertl, Christoph;
Willershausen, Ines;
Weber, Manuel;
Hoerning, André;
Morhart, Patrick;
Schneider, Michael;
Beckmann, Matthias W.;
Bogdan, Christian;
Gerlach, Roman G.;
Gölz, Lina

Publication type:

Article

HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting.

Published in:

Autophagy, 2019, v. 15, n. 11, p. 1899, doi. 10.1080/15548627.2019.1596483

By:

Neubert, Patrick;
Weichselbaum, Andrea;
Reitinger, Carmen;
Schatz, Valentin;
Schröder, Agnes;
Ferdinand, John R.;
Simon, Michaela;
Bär, Anna-Lorena;
Brochhausen, Christoph;
Gerlach, Roman G.;
Tomiuk, Stefan;
Hammer, Karin;
Wagner, Stefan;
van Zandbergen, Ger;
Binger, Katrina J.;
Müller, Dominik N.;
Kitada, Kento;
Clatworthy, Menna R.;
Kurts, Christian;
Titze, Jens

Publication type:

Article

Loss of the Periplasmic Chaperone Skp and Mutations in the Efflux Pump AcrAB-TolC Play a Role in Acquired Resistance to Antimicrobial Peptides in Salmonella typhimurium.

Published in:

Frontiers in Microbiology, 2020, p. 1, doi. 10.3389/fmicb.2020.00189

By:

Kapach, Gal;
Nuri, Reut;
Schmidt, Christiane;
Danin, Adi;
Ferrera, Shir;
Savidor, Alon;
Gerlach, Roman G.;
Shai, Yechiel

Publication type:

Article

Scarless deletion of up to seven methyl-accepting chemotaxis genes with an optimized method highlights key function of CheM in Salmonella Typhimurium.

Published in:

PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0172630

By:

Hoffmann, Stefanie;
Schmidt, Christiane;
Walter, Steffi;
Bender, Jennifer K.;
Gerlach, Roman G.

Publication type:

Article

Structural and functional characterization of SiiA, an auxiliary protein from the SPI4‐encoded type 1 secretion system from Salmonella enterica.

Published in:

Molecular Microbiology, 2019, v. 112, n. 5, p. 1403, doi. 10.1111/mmi.14368

By:

Kirchweger, Peter;
Weiler, Sigrid;
Egerer‐Sieber, Claudia;
Blasl, Anna‐Theresa;
Hoffmann, Stefanie;
Schmidt, Christiane;
Sander, Nathalie;
Merker, Dorothee;
Gerlach, Roman G.;
Hensel, Michael;
Muller, Yves A.

Publication type:

Article

Distinct gut microbial signature and altered short chain fatty acid metabolism at disease onset in a rat preclinical model of superimposed preeclampsia.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-83981-5

By:

Alhasan, Moumen M.;
Landa, María S.;
García, Silvia I.;
Gerlach, Roman G.;
Harb, Hani;
Fahlbusch, Fabian B.;
Conrad, Melanie L.;
Barrientos, Gabriela

Publication type:

Article

Application of Next-Generation Sequencing to Enterobacter Hormaechei Subspecies Analysis during a Neonatal Intensive Care Unit Outbreak.

Published in:

Children, 2023, v. 10, n. 10, p. 1696, doi. 10.3390/children10101696

By:

Morhart, Patrick;
Gerlach, Roman G.;
Kunz, Caroline;
Held, Jürgen;
Valenza, Giuseppe;
Wölfle, Joachim;
Reutter, Heiko;
Hanslik, Gregor J.;
Fahlbusch, Fabian B.

Publication type:

Article

Structural and functional dissection reveals distinct roles of Ca2+-binding sites in the giant adhesin SiiE of Salmonella enterica.

Published in:

PLoS Pathogens, 2017, v. 13, n. 5, p. 1, doi. 10.1371/journal.ppat.1006418

By:

Peters, Britta;
Stein, Johanna;
Klingl, Stefan;
Sander, Nathalie;
Sandmann, Achim;
Taccardi, Nicola;
Sticht, Heinrich;
Gerlach, Roman G.;
Muller, Yves A.;
Hensel, Michael

Publication type:

Article

Defining Metaniches in the Oral Cavity According to Their Microbial Composition and Cytokine Profile.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 21, p. 8218, doi. 10.3390/ijms21218218

By:

Seidel, Corinna L.;
Gerlach, Roman G.;
Wiedemann, Patrick;
Weider, Matthias;
Rodrian, Gabriele;
Hader, Michael;
Frey, Benjamin;
Gaipl, Udo S.;
Bozec, Aline;
Cieplik, Fabian;
Kirschneck, Christian;
Bogdan, Christian;
Gölz, Lina

Publication type:

Article

B cell fate mapping reveals their contribution to the memory immune response against helminths.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1016142

By:

Haase, Paul;
Schäfer, Simon;
Gerlach, Roman G.;
Winkler, Thomas H.;
Voehringer, David

Publication type:

Article

Influence of probiotics on the periodontium, the oral microbiota and the immune response during orthodontic treatment in adolescent and adult patients (ProMB Trial): study protocol for a prospective, double-blind, controlled, randomized clinical trial.

Published in:

BMC Oral Health, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12903-022-02180-8

By:

Seidel, Corinna L.;
Gerlach, Roman G.;
Weider, Matthias;
Wölfel, Theresa;
Schwarz, Vincent;
Ströbel, Armin;
Schmetzer, Helga;
Bogdan, Christian;
Gölz, Lina

Publication type:

Article

High-Throughput Quantification of Bacterial-Cell Interactions Using Virtual Colony Counts.

Published in:

Frontiers in Cellular & Infection Microbiology, 2018, v. 8, p. 1, doi. 10.3389/fcimb.2018.00043

By:

Hoffmann, Stefanie;
Walter, Steffi;
Blume, Anne-Kathrin;
Fuchs, Stephan;
Schmidt, Christiane;
Scholz, Annemarie;
Gerlach, Roman G.

Publication type:

Article

Cross talk between the response regulators PhoB and TctD allows for the integration of diverse environmental signals in Pseudomonas aeruginosa.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 13, p. 6413, doi. 10.1093/nar/gkv599

By:

Bielecki, Piotr;
Jensen, Vanessa;
Schulze, Wiebke;
Gödeke, Julia;
Strehmel, Janine;
Eckweiler, Denitsa;
Nicolai, Tanja;
Bielecka, Agata;
Wille, Thorsten;
Gerlach, Roman G.;
Häussler, Susanne

Publication type:

Article

Works by Gerlach, Roman G.

Increased zinc levels facilitate phenotypic detection of ceftazidime-avibactam resistance in metallo-β-lactamase-producing Gram-negative bacteria.

Enhanced invasion and survival of antibiotic- resistant Klebsiella pneumoniae pathotypes in host cells and strain-specific replication in blood.

O<sub>2</sub>-dependent incapacitation of the Salmonella pathogenicity island 1 repressor HilE.

Subversion of a family of antimicrobial proteins by Salmonella enterica.

Inflammation Fuels Colicin Ib-Dependent Competition of <i>Salmonella</i> Serovar Typhimurium and <i>E. coli</i> in <i>Enterobacterial</i> Blooms.

Low-oxygen tensions found in S almonella-infected gut tissue boost S almonella replication in macrophages by impairing antimicrobial activity and augmenting S almonella virulence.

The S almonella enterica giant adhesin SiiE binds to polarized epithelial cells in a lectin-like manner.

SiiA and SiiB are novel type I secretion system subunits controlling SPI4-mediated adhesion of S almonella enterica.

Functional dissection of SiiE, a giant non-fimbrial adhesin of Salmonella enterica.

Cooperation of Salmonella pathogenicity islands 1 and 4 is required to breach epithelial barriers.

Salmonella Pathogenicity Island 4 encodes a giant non-fimbrial adhesin and the cognate type 1 secretion system.

Scalable Reporter Assays to Analyze the Regulation of stx2 Expression in Shiga Toxin-Producing Enteropathogens.

A Gateway-Based System for Fast Evaluation of Protein-Protein Interactions in Bacteria.

LPS Structure and PhoQ Activity Are Important for Salmonella Typhimurium Virulence in the Gallleria mellonella Infection Model.

Rapid and Highly Efficient Method for Scarless Mutagenesis within the Salmonella enterica Chromosome.

Corynebacterium diphtheriae invasion-associated protein (DIP1281) is involved in cell surface organization, adhesion and internalization in epithelial cells.

Temperate phages promote colicin-dependent fitness of S almonella enterica serovar Typhimurium.

L-arginine metabolism as pivotal interface of mutual host–microbe interactions in the gut.

Orofacial clefts alter early life oral microbiome maturation towards higher levels of potentially pathogenic species: A prospective observational study.

HIF1A and NFAT5 coordinate Na<sup>+</sup>-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting.

Loss of the Periplasmic Chaperone Skp and Mutations in the Efflux Pump AcrAB-TolC Play a Role in Acquired Resistance to Antimicrobial Peptides in Salmonella typhimurium.

Scarless deletion of up to seven methyl-accepting chemotaxis genes with an optimized method highlights key function of CheM in Salmonella Typhimurium.

Structural and functional characterization of SiiA, an auxiliary protein from the SPI4‐encoded type 1 secretion system from Salmonella enterica.

Distinct gut microbial signature and altered short chain fatty acid metabolism at disease onset in a rat preclinical model of superimposed preeclampsia.

Application of Next-Generation Sequencing to Enterobacter Hormaechei Subspecies Analysis during a Neonatal Intensive Care Unit Outbreak.

Structural and functional dissection reveals distinct roles of Ca<sup>2+</sup>-binding sites in the giant adhesin SiiE of Salmonella enterica.

Defining Metaniches in the Oral Cavity According to Their Microbial Composition and Cytokine Profile.

B cell fate mapping reveals their contribution to the memory immune response against helminths.

Influence of probiotics on the periodontium, the oral microbiota and the immune response during orthodontic treatment in adolescent and adult patients (ProMB Trial): study protocol for a prospective, double-blind, controlled, randomized clinical trial.

High-Throughput Quantification of Bacterial-Cell Interactions Using Virtual Colony Counts.

Cross talk between the response regulators PhoB and TctD allows for the integration of diverse environmental signals in Pseudomonas aeruginosa.