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Inhibition of myeloperoxidase to treat left ventricular dysfunction in non‐ischaemic cardiomyopathy.
Published in:
European Journal of Heart Failure, 2024, v. 26, n. 10, p. 2269, doi. 10.1002/ejhf.3435
By:
- Geissen, Simon;
- Braumann, Simon;
- Adler, Joana;
- Nettersheim, Felix Sebastian;
- Mehrkens, Dennis;
- Hof, Alexander;
- Guthoff, Henning;
- von Stein, Philipp;
- Witkowski, Sven;
- Gerdes, Norbert;
- Tellkamp, Frederik;
- Krüger, Marcus;
- Isermann, Lea;
- Trifunovic, Aleksandra;
- Bunck, Alexander C.;
- Mollenhauer, Martin;
- Winkels, Holger;
- Adam, Matti;
- Klinke, Anna;
- Buch, Gregor
Publication type:
Article
Physical Fitness and Cardiovascular Risk Factors in Novel Diabetes Subgroups.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 4, p. 1127, doi. 10.1210/clinem/dgab810
By:
- Saatmann, Nina;
- Zaharia, Oana-Patricia;
- Strassburger, Klaus;
- Pesta, Dominik Hans;
- Burkart, Volker;
- Szendroedi, Julia;
- Gerdes, Norbert;
- Kelm, Malte;
- Roden, Michael
Publication type:
Article
Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis.
Published in:
2013
By:
- Klingenberg, Roland;
- Gerdes, Norbert;
- Badeau, Robert M;
- Gisterå, Anton;
- Strodthoff, Daniela;
- Ketelhuth, Daniel F J;
- Lundberg, Anna M;
- Rudling, Mats;
- Nilsson, Stefan K;
- Olivecrona, Gunilla;
- Zoller, Stefan;
- Lohmann, Christine;
- Lüscher, Thomas F;
- Jauhiainen, Matti;
- Sparwasser, Tim;
- Hansson, Göran K
Publication type:
journal article
Depletion of FOXP3<sup>+</sup> regulatory T cells promotes hypercholesterolemia and atherosclerosis.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 3, p. 1323, doi. 10.1172/JCI63891
By:
- Klingenberg, Roland;
- Gerdes, Norbert;
- Badeau, Robert M.;
- Gisterå, Anton;
- Strodthoff, Daniela;
- Ketelhuth, Daniel F. J.;
- Lundberg, Anna M.;
- Rudling, Mats;
- Nilsson, Stefan K.;
- Olivecrona, Gunilla;
- Zoller, Stefan;
- Lohmann, Christine;
- Lüscher, Thomas F.;
- Jauhiainen, Matti;
- Sparwasser, Tim;
- Hansson, Göran K.
Publication type:
Article
Rational and design of the REMOTE trial: An exploratory, pilot study to analyze REtinal MicrOcirculaTion in wEightlessness.
Published in:
Clinical Hemorheology & Microcirculation, 2023, v. 84, n. 4, p. 449, doi. 10.3233/CH-221691
By:
- Binneboessel, Stephan;
- Masyuk, Maryna;
- Piayda, Kerstin;
- Bruno, Raphael Romano;
- Wernly, Bernhard;
- Jirak, Peter;
- Wolff, Georg;
- Gerdes, Norbert;
- Baldia, Philipp Heinrich;
- Kelm, Malte;
- Nienhaus, Fabian;
- Lang, Alexander;
- Winkels, Holger;
- Geerling, Gerd;
- Guthoff, Rainer;
- Kaya, Sema;
- Flossmann, Gerald;
- Riemer, Thomas;
- Baertschi, Michael;
- Jung, Christian
Publication type:
Article
Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter.
Published in:
Nature Medicine, 2015, v. 21, n. 7, p. 820, doi. 10.1038/nm.3890
By:
- Wang, Jing;
- Sun, Chongxiu;
- Gerdes, Norbert;
- Liu, Conglin;
- Liao, Mengyang;
- Liu, Jian;
- Shi, Michael A;
- He, Aina;
- Zhou, Yi;
- Sukhova, Galina K;
- Chen, Huimei;
- Cheng, Xian Wu;
- Kuzuya, Masafumi;
- Murohara, Toyoaki;
- Zhang, Jie;
- Cheng, Xiang;
- Jiang, Mengmeng;
- Shull, Gary E;
- Rogers, Shaunessy;
- Yang, Chao-Ling
Publication type:
Article
Full-length transcriptomic analysis in murine and human heart reveals diversity of PGC-1α promoters and isoforms regulated distinctly in myocardial ischemia and obesity.
Published in:
BMC Biology, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12915-022-01360-w
By:
- Oehler, Daniel;
- Spychala, André;
- Gödecke, Axel;
- Lang, Alexander;
- Gerdes, Norbert;
- Ruas, Jorge;
- Kelm, Malte;
- Szendroedi, Julia;
- Westenfeld, Ralf
Publication type:
Article
Eosinophils promote vascular calcification and atherosclerosis: adding another layer of complexity on the path to clarity?
Published in:
European Heart Journal, 2023, v. 44, n. 29, p. 2784, doi. 10.1093/eurheartj/ehad323
By:
- Gerdes, Norbert
Publication type:
Article
Single-cell transcriptomics defines heterogeneity of epicardial cells and fibroblasts within the infarcted murine heart.
Published in:
eLife, 2021, p. 1, doi. 10.7554/eLife.65921
By:
- Hesse, Julia;
- Owenier, Christoph;
- Lautwein, Tobias;
- Zalfen, Ria;
- Weber, Jonas F.;
- Zhaoping Ding;
- Alter, Christina;
- Lang, Alexander;
- Grandoch, Maria;
- Gerdes, Norbert;
- Fischer, Jens W.;
- Klau, Gunnar W.;
- Dieterich, Christoph;
- Köhrer, Karl;
- Schrader, Jürgen
Publication type:
Article
Design of a Robust Flow Cytometric Approach for Phenotypical and Functional Analysis of Human Monocyte Subsets in Health and Disease.
Published in:
Biomolecules (2218-273X), 2024, v. 14, n. 10, p. 1251, doi. 10.3390/biom14101251
By:
- Ahrazoglu, Talia;
- Kluczny, Jennifer Isabel;
- Kleimann, Patricia;
- Irschfeld, Lisa-Marie;
- Nienhaus, Fabian Theodor;
- Bönner, Florian;
- Gerdes, Norbert;
- Temme, Sebastian
Publication type:
Article
Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis.
Published in:
Cardiovascular Research, 2013, v. 99, n. 2, p. 364, doi. 10.1093/cvr/cvt033
By:
- Lundberg, Anna M.;
- Ketelhuth, Daniel F.J.;
- Johansson, Maria E.;
- Gerdes, Norbert;
- Liu, Sang;
- Yamamoto, Masahiro;
- Akira, Shizuo;
- Hansson, Göran K.
Publication type:
Article
Short-term delivery of anti-PlGF antibody delays progression of atherosclerotic plaques to vulnerable lesions.
Published in:
Cardiovascular Research, 2010, v. 86, n. 1, p. 29, doi. 10.1093/cvr/cvp380
By:
- Roncal, Carmen;
- Buysschaert, Ian;
- Gerdes, Norbert;
- Georgiadou, Maria;
- Ovchinnikova, Olga;
- Fischer, Christian;
- Stassen, Jean-Marie;
- Moons, Lieve;
- Collen, Désiré;
- De Bock, Katrien;
- Hansson, Göran K.;
- Carmeliet, Peter
Publication type:
Article
Depletion of CD40 on CD11c<sup>+</sup> cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-50976-6
By:
- Aarts, Suzanne;
- Reiche, Myrthe;
- den Toom, Myrthe;
- Gijbels, Marion;
- Beckers, Linda;
- Gerdes, Norbert;
- Lutgens, Esther
Publication type:
Article
Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages' transition into a pro-inflammatory state.
Published in:
Cardiovascular Research, 2023, v. 119, n. 5, p. 1146, doi. 10.1093/cvr/cvac084
By:
- Bosmans, Laura A;
- Tiel, Claudia M van;
- Aarts, Suzanne A B M;
- Willemsen, Lisa;
- Baardman, Jeroen;
- Os, Bram W van;
- Toom, Myrthe den;
- Beckers, Linda;
- Ahern, David J;
- Levels, Johannes H M;
- Jongejan, Aldo;
- Moerland, Perry D;
- Verberk, Sanne G S;
- van den Bossche, Jan;
- Winther, Menno M P J de;
- Weber, Christian;
- Atzler, Dorothee;
- Monaco, Claudia;
- Gerdes, Norbert;
- Shami, Annelie
Publication type:
Article
Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential.
Published in:
Cellular & Molecular Life Sciences, 2016, v. 73, n. 5, p. 901, doi. 10.1007/s00018-015-2080-2
By:
- Spitz, Charlotte;
- Winkels, Holger;
- Bürger, Christina;
- Weber, Christian;
- Lutgens, Esther;
- Hansson, Göran;
- Gerdes, Norbert
Publication type:
Article
Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis.
Published in:
FASEB Journal, 2018, v. 32, n. 8, p. 4428, doi. 10.1096/fj.201800058R
By:
- Schmitz, Corinna;
- Noels, Heidi;
- El Bounkari, Omar;
- Straussfeld, Eva;
- Megens, Remco T. A.;
- Sternkopf, Marieke;
- Alampour-Rajabi, Setareh;
- Krammer, Christine;
- Tilstam, Pathricia V.;
- Gerdes, Norbert;
- Bürger, Christina;
- Kapurniotu, Aphrodite;
- Bucala, Richard;
- Jankowski, Joachim;
- Weber, Christian;
- Bernhagen, Jürgen
Publication type:
Article
Caveolin-1 deficiency decreases atherosclerosis by hampering leukocyte influx into the arterial wall and generating a regulatory T-cell response.
Published in:
FASEB Journal, 2011, v. 25, n. 11, p. 3838, doi. 10.1096/fj.11-183350
By:
- Engel, David;
- Beckers, Linda;
- Wijnands, Erwin;
- Seijkens, Tom;
- Lievens, Dirk;
- Drechsler, Maik;
- Gerdes, Norbert;
- Soehnlein, Oliver;
- Daemen, Mat J. A. P.;
- Stan, Radu V.;
- Biessen, Erik A. L.;
- Lutgens, Esther
Publication type:
Article
Colchicine prevents oxidative stress-induced endothelial cell senescence via blocking NF-κB and MAPKs: implications in vascular diseases.
Published in:
Journal of Inflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12950-023-00366-7
By:
- Zhou, Huakang;
- Khan, Dilaware;
- Hussain, Sajid Muhammad;
- Gerdes, Norbert;
- Hagenbeck, Carsten;
- Rana, Majeed;
- Cornelius, Jan Frederick;
- Muhammad, Sajjad
Publication type:
Article
PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function.
Published in:
Science Immunology, 2019, v. 4, n. 36, p. 1, doi. 10.1126/sciimmunol.aar3054
By:
- Bianchini, Mariaelvy;
- Duchêne, Johan;
- Santovito, Donato;
- Schloss, Maximilian J.;
- Evrard, Maximilien;
- Winkels, Holger;
- Aslani, Maria;
- Mohanta, Sarajo K.;
- Horckmans, Michael;
- Blanchet, Xavier;
- Lacy, Michael;
- von Hundelshausen, Philipp;
- Atzler, Dorothee;
- Habenicht, Andreas;
- Gerdes, Norbert;
- Pelisek, Jaroslav;
- Ng, Lai Guan;
- Steffens, Sabine;
- Weber, Christian;
- Megens, Remco T. A.
Publication type:
Article
Safety and efficacy of iron supplementation after myocardial infarction in mice with moderate blood loss anaemia.
Published in:
ESC Heart Failure, 2021, v. 8, n. 6, p. 5445, doi. 10.1002/ehf2.13639
By:
- Wischmann, Patricia;
- Chennupati, Ramesh;
- Solga, Isabella;
- Funk, Felix;
- Becher, Stefanie;
- Gerdes, Norbert;
- Anker, Stefan;
- Kelm, Malte;
- Jung, Christian
Publication type:
Article
Colchicine Protects against Ethanol-Induced Senescence and Senescence-Associated Secretory Phenotype in Endothelial Cells.
Published in:
Antioxidants, 2023, v. 12, n. 4, p. 960, doi. 10.3390/antiox12040960
By:
- Zhou, Huakang;
- Khan, Dilaware;
- Gerdes, Norbert;
- Hagenbeck, Carsten;
- Rana, Majeed;
- Cornelius, Jan Frederick;
- Muhammad, Sajjad
Publication type:
Article
The collagen receptor glycoprotein VI promotes platelet-mediated aggregation of β-amyloid.
Published in:
Science Signaling, 2020, v. 13, n. 643, p. 1, doi. 10.1126/scisignal.aba9872
By:
- Donner, Lili;
- Toska, Laura Mara;
- Krüger, Irena;
- Gröniger, Sandra;
- Barroso, Ruben;
- Burleigh, Alice;
- Mezzano, Diego;
- Pfeiler, Susanne;
- Kelm, Malte;
- Gerdes, Norbert;
- Watson, Steve P.;
- Sun, Yi;
- Elvers, Margitta
Publication type:
Article
Circulating Levels of Interleukin-1 Family Cytokines in Overweight Adolescents.
Published in:
Mediators of Inflammation, 2010, v. 2010, p. 1, doi. 10.1155/2010/958403
By:
- Jung, Christian;
- Gerdes, Norbert;
- Fritzenwanger, Michael;
- Figulla, Hans Reiner
Publication type:
Article
A Model of Blood Component-Heart Interaction in Cardiac Ischemia-Reperfusion Injury using a Langendorff-Based Ex Vivo Assay.
Published in:
2020
By:
- Muessig, Johanna M.;
- Kaya, Sema;
- Moellhoff, Luise;
- Noelle, Johanna;
- Hidalgo Pareja, Leonie;
- Masyuk, Maryna;
- Gerdes, Norbert;
- Pernow, John;
- Kelm, Malte;
- Jung, Christian
Publication type:
journal article
Mini-Review: Immunogenic epitopes in apolipoprotein B-100 for atheroprotective immunization.
Published in:
Frontiers in Cardiovascular Medicine, 2024, p. 1, doi. 10.3389/fcvm.2024.1448664
By:
- Gerdes, Norbert;
- Klingenberg, Roland
Publication type:
Article
Mitochondrial Creatine Kinase 2 (Ckmt2) as a Plasma-Based Biomarker for Evaluating Reperfusion Injury in Acute Myocardial Infarction.
Published in:
Biomedicines, 2024, v. 12, n. 10, p. 2368, doi. 10.3390/biomedicines12102368
By:
- Lang, Alexander;
- Oehler, Daniel;
- Benkhoff, Marcel;
- Reinders, Yvonne;
- Barcik, Maike;
- Shahrjerdi, Khatereh;
- Kaldirim, Madlen;
- Sickmann, Albert;
- Dannenberg, Lisa;
- Polzin, Amin;
- Pfeiler, Susanne;
- Kelm, Malte;
- Grandoch, Maria;
- Jung, Christian;
- Gerdes, Norbert
Publication type:
Article
Alterations in systemic levels of Th1, Th2, and Th17 cytokines in overweight adolescents and obese mice.
Published in:
Pediatric Diabetes, 2017, v. 18, n. 8, p. 714, doi. 10.1111/pedi.12435
By:
- Jung, Christian;
- Lichtenauer, Michael;
- Strodthoff, Daniela;
- Winkels, Holger;
- Wernly, Bernhard;
- Bürger, Christina;
- Kamchybekov, Uran;
- Lutgens, Esther;
- Figulla, Hans‐Reiner;
- Gerdes, Norbert
Publication type:
Article
Novel Fluorescence-Based Methods to Determine Infarct and Scar Size in Murine Models of Reperfused Myocardial Infarction.
Published in:
Cells (2073-4409), 2024, v. 13, n. 19, p. 1633, doi. 10.3390/cells13191633
By:
- Duplessis, Ashley;
- Elster, Christin;
- Becher, Stefanie;
- Engel, Christina;
- Lang, Alexander;
- Kaldirim, Madlen;
- Jung, Christian;
- Grandoch, Maria;
- Kelm, Malte;
- Pfeiler, Susanne;
- Gerdes, Norbert
Publication type:
Article
Recombinant Acetylcholine Receptor Immunization Induces a Robust Model of Experimental Autoimmune Myasthenia Gravis in Mice.
Published in:
Cells (2073-4409), 2024, v. 13, n. 6, p. 508, doi. 10.3390/cells13060508
By:
- Theissen, Lukas;
- Schroeter, Christina B.;
- Huntemann, Niklas;
- Räuber, Saskia;
- Dobelmann, Vera;
- Cengiz, Derya;
- Herrmann, Alexander;
- Koch-Hölsken, Kathrin;
- Gerdes, Norbert;
- Hu, Hao;
- Mourikis, Philipp;
- Polzin, Amin;
- Kelm, Malte;
- Hartung, Hans-Peter;
- Meuth, Sven G.;
- Nelke, Christopher;
- Ruck, Tobias
Publication type:
Article
Phagocytosis of a PFOB-Nanoemulsion for 19F Magnetic Resonance Imaging: First Results in Monocytes of Patients with Stable Coronary Artery Disease and ST-Elevation Myocardial Infarction.
Published in:
Molecules, 2019, v. 24, n. 11, p. 2058, doi. 10.3390/molecules24112058
By:
- Nienhaus, Fabian;
- Colley, Denise;
- Jahn, Annika;
- Pfeiler, Susanne;
- Flocke, Vera;
- Temme, Sebastian;
- Kelm, Malte;
- Gerdes, Norbert;
- Flögel, Ulrich;
- Bönner, Florian;
- Cicha, Iwona;
- Dézsi, László;
- Azzawi, May
Publication type:
Article
Levels of Th2 chemokine CCL27 in adolescents: No impact of obesity.
Published in:
2009
By:
- Jung, Christian;
- Gerdes, Norbert;
- Fritzenwanger, Michael;
- Figulla, Hans R.
Publication type:
Letter
Acute Heart Failure After Reperfused Ischemic Stroke: Association With Systemic and Cardiac Inflammatory Responses.
Published in:
Frontiers in Physiology, 2021, v. 12, p. 1, doi. 10.3389/fphys.2021.782760
By:
- Vornholz, Lilian;
- Nienhaus, Fabian;
- Gliem, Michael;
- Alter, Christina;
- Henning, Carina;
- Lang, Alexander;
- Ezzahoini, Hakima;
- Wolff, Georg;
- Clasen, Lukas;
- Rassaf, Tienush;
- Flögel, Ulrich;
- Kelm, Malte;
- Gerdes, Norbert;
- Jander, Sebastian;
- Bönner, Florian
Publication type:
Article
Macrophage CD40 plays a minor role in obesity-induced metabolic dysfunction.
Published in:
PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0202150
By:
- Aarts, Suzanne A. B. M.;
- Reiche, Myrthe E.;
- den Toom, Myrthe;
- Beckers, Linda;
- Gijbels, Marion J. J.;
- de Winther, Menno P. J.;
- Lutgens, Esther;
- Gerdes, Norbert
Publication type:
Article
Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis.
Published in:
European Heart Journal, 2013, v. 34, n. 48, p. 3717, doi. 10.1093/eurheartj/ehs106
By:
- Lievens, Dirk;
- Habets, Kim L.;
- Robertson, Anna-Karin;
- Laouar, Yasmina;
- Winkels, Holger;
- Rademakers, Timo;
- Beckers, Linda;
- Wijnands, Erwin;
- Boon, Louis;
- Mosaheb, Munir;
- Ait-Oufella, Hafid;
- Mallat, Ziad;
- Flavell, Richard A.;
- Rudling, Mats;
- Binder, Christoph J.;
- Gerdes, Norbert;
- Biessen, Erik A.L.;
- Weber, Christian;
- Daemen, Mat J.A.P.;
- Kuiper, Johan
Publication type:
Article
Acute and short-term fluctuations in gravity are associated with changes in circulatory plasma protein levels.
Published in:
NPJ Microgravity, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41526-024-00370-y
By:
- Lang, Alexander;
- Binneboessel, Stephan;
- Nienhaus, Fabian;
- Bruno, Raphael Romano;
- Wolff, Georg;
- Piayda, Kerstin;
- Pfeiler, Susanne;
- Ezzahoini, Hakima;
- Oehler, Daniel;
- Kelm, Malte;
- Winkels, Holger;
- Gerdes, Norbert;
- Jung, Christian
Publication type:
Article
Elevated Plasma Levels of Interleukin-12p40 and Interleukin-16 in Overweight Adolescents.
Published in:
BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/940910
By:
- Lichtenauer, Michael;
- Franz, Marcus;
- Fritzenwanger, Michael;
- Figulla, Hans-Reiner;
- Gerdes, Norbert;
- Jung, Christian
Publication type:
Article

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