Works by Georgakilas, Alexandros G.

Results: 71

Processing of bistranded abasic DNA clusters in γ-irradiated human hematopoietic cells.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 18, p. 5609, doi. 10.1093/nar/gkh871

By:

Georgakilas, Alexandros G.;
Bennett, Paula V.;
Wilson, David M.;
Sutherland, Betsy M.

Publication type:

Article

High efficiency detection of bi-stranded abasic clusters in γ-irradiated DNA by putrescine.

Published in:

Nucleic Acids Research, 2002, v. 30, n. 13, p. 2800, doi. 10.1093/nar/gkf393

By:

Georgakilas, Alexandros G.;
Bennett, Paula V.;
Sutherland, Betsy M.

Publication type:

Article

Computer-Aided Identification and Design of Ligands for Multi-Targeting Inhibition of a Molecular Acute Myeloid Leukemia Network.

Published in:

Cancers, 2024, v. 16, n. 21, p. 3607, doi. 10.3390/cancers16213607

By:

Asfa, Seyedeh Sadaf;
Arshinchi Bonab, Reza;
Önder, Onur;
Uça Apaydın, Merve;
Döşeme, Hatice;
Küçük, Can;
Georgakilas, Alexandros G.;
Stadler, Bernhard M.;
Logotheti, Stella;
Kale, Seyit;
Pavlopoulou, Athanasia

Publication type:

Article

The Role of Human Endogenous Retroviruses in Cancer Immunotherapy of the Post-COVID-19 World.

Published in:

2023

By:

Logotheti, Stella;
Stiewe, Thorsten;
Georgakilas, Alexandros G.

Publication type:

Editorial

More than Meets the Eye: Integration of Radiomics with Transcriptomics for Reconstructing the Tumor Microenvironment and Predicting Response to Therapy.

Published in:

2023

By:

Logotheti, Stella;
Georgakilas, Alexandros G.

Publication type:

Editorial

Biological Response of Human Cancer Cells to Ionizing Radiation in Combination with Gold Nanoparticles.

Published in:

Cancers, 2022, v. 14, n. 20, p. 5086, doi. 10.3390/cancers14205086

By:

Tremi, Ioanna;
Havaki, Sophia;
Georgitsopoulou, Sofia;
Terzoudi, Georgia;
Lykakis, Ioannis N.;
Iliakis, George;
Georgakilas, Vasilios;
Gorgoulis, Vassilis G.;
Georgakilas, Alexandros G.

Publication type:

Article

Requirements for Designing an Effective Metallic Nanoparticle (NP)-Boosted Radiation Therapy (RT).

Published in:

Cancers, 2021, v. 13, n. 13, p. 3185, doi. 10.3390/cancers13133185

By:

Tremi, Ioanna;
Spyratou, Ellas;
Souli, Maria;
Efstathopoulos, Efstathios P.;
Makropoulou, Mersini;
Georgakilas, Alexandros G.;
Sihver, Lembit

Publication type:

Article

Mechanistic Modelling of Slow and Fast NHEJ DNA Repair Pathways Following Radiation for G0/G1 Normal Tissue Cells.

Published in:

Cancers, 2021, v. 13, n. 9, p. 2202, doi. 10.3390/cancers13092202

By:

Qi, Yaping;
Warmenhoven, John William;
Henthorn, Nicholas Thomas;
Ingram, Samuel Peter;
Xu, Xie George;
Kirkby, Karen Joy;
Merchant, Michael John;
Georgakilas, Alexandros G.

Publication type:

Article

Antitumor Activity of Protons and Molecular Hydrogen: Underlying Mechanisms.

Published in:

Cancers, 2021, v. 13, n. 4, p. 893, doi. 10.3390/cancers13040893

By:

Rochette, Luc;
Zeller, Marianne;
Cottin, Yves;
Vergely, Catherine;
Patankar, Manish S.;
Georgakilas, Alexandros G.

Publication type:

Article

In Situ Detection of Complex DNA Damage Using Microscopy: A Rough Road Ahead.

Published in:

Cancers, 2020, v. 12, n. 11, p. 3288, doi. 10.3390/cancers12113288

By:

Nikitaki, Zacharenia;
Pariset, Eloise;
Sudar, Damir;
Costes, Sylvain V.;
Georgakilas, Alexandros G.

Publication type:

Article

Interphase Cytogenetic Analysis of G0 Lymphocytes Exposed to α-Particles, C-Ions, and Protons Reveals their Enhanced Effectiveness for Localized Chromosome Shattering—A Critical Risk for Chromothripsis.

Published in:

Cancers, 2020, v. 12, n. 9, p. 2336, doi. 10.3390/cancers12092336

By:

Pantelias, Antonio;
Zafiropoulos, Demetre;
Cherubini, Roberto;
Sarchiapone, Lucia;
De Nadal, Viviana;
Pantelias, Gabriel E.;
Georgakilas, Alexandros G.;
Terzoudi, Georgia I.

Publication type:

Article

Ionizing Radiation and Complex DNA Damage: Quantifying the Radiobiological Damage Using Monte Carlo Simulations.

Published in:

Cancers, 2020, v. 12, n. 4, p. 799, doi. 10.3390/cancers12040799

By:

Chatzipapas, Konstantinos P.;
Papadimitroulas, Panagiotis;
Emfietzoglou, Dimitris;
Kalospyros, Spyridon A.;
Hada, Megumi;
Georgakilas, Alexandros G.;
Kagadis, George C.

Publication type:

Article

Ionizing Radiation and Complex DNA Damage: From Prediction to Detection Challenges and Biological Significance.

Published in:

Cancers, 2019, v. 11, n. 11, p. 1789, doi. 10.3390/cancers11111789

By:

Mavragani, Ifigeneia V.;
Nikitaki, Zacharenia;
Kalospyros, Spyridon A.;
Georgakilas, Alexandros G.

Publication type:

Article

Interphase Cytogenetic Analysis of Micronucleated and Multinucleated Cells Supports the Premature Chromosome Condensation Hypothesis as the Mechanistic Origin of Chromothripsis.

Published in:

Cancers, 2019, v. 11, n. 8, p. 1123, doi. 10.3390/cancers11081123

By:

Pantelias, Antonio;
Karachristou, Ioanna;
Georgakilas, Alexandros G.;
Terzoudi, Georgia I.

Publication type:

Article

Duodenal carcinoma at the ligament of Treitz. A molecular and clinical perspective.

Published in:

BMC Gastroenterology, 2010, v. 10, p. 109, doi. 10.1186/1471-230X-10-109

By:

Kalogerinis, Peter T.;
Poulos, John E.;
Morfesis, Andrew;
Daniels, Anthony;
Georgakila, Stavroula;
Daignualt, Thomas;
Georgakilas, Alexandros G.

Publication type:

Article

In Silico Investigation of the Biological Implications of Complex DNA Damage with Emphasis in Cancer Radiotherapy through a Systems Biology Approach.

Published in:

Molecules, 2021, v. 26, n. 24, p. 7602, doi. 10.3390/molecules26247602

By:

Pavlopoulou, Athanasia;
Asfa, Seyedehsadaf;
Gioukakis, Evangelos;
Mavragani, Ifigeneia V.;
Nikitaki, Zacharenia;
Takan, Işıl;
Pouget, Jean-Pierre;
Harrison, Lynn;
Georgakilas, Alexandros G.

Publication type:

Article

A Mathematical Radiobiological Model (MRM) to Predict Complex DNA Damage and Cell Survival for Ionizing Particle Radiations of Varying Quality.

Published in:

Molecules, 2021, v. 26, n. 4, p. 840, doi. 10.3390/molecules26040840

By:

Kalospyros, Spyridon A.;
Nikitaki, Zacharenia;
Kyriakou, Ioanna;
Kokkoris, Michael;
Emfietzoglou, Dimitris;
Georgakilas, Alexandros G.;
Roca-Sanjuán, Daniel;
Lhiaubet-Vallet, Virginie L.;
Tuñón, Iñaki;
Correia, João D. G.

Publication type:

Article

Construction and evaluation of an α-particle-irradiation exposure apparatus.

Published in:

International Journal of Radiation Biology, 2021, v. 97, n. 10, p. 1404, doi. 10.1080/09553002.2021.1962568

By:

Nikitaki, Zacharenia;
Choulilitsa, Evangelia;
Kalospyros, Spyridon A.;
Kaisaridi, Sofia;
Terzoudi, Georgia I.;
Kokkoris, Mike;
Georgakilas, Alexandros G.

Publication type:

Article

Combined radiation strategies for novel and enhanced cancer treatment.

Published in:

International Journal of Radiation Biology, 2020, v. 96, n. 9, p. 1087, doi. 10.1080/09553002.2020.1787544

By:

Kareliotis, Georgios;
Tremi, Ioanna;
Kaitatzi, Myrsini;
Drakaki, Eleni;
Serafetinides, Alexandros A.;
Makropoulou, Mersini;
Georgakilas, Alexandros G.

Publication type:

Article

The challenge of drug resistance in cancer treatment: a current overview.

Published in:

Clinical & Experimental Metastasis, 2018, v. 35, n. 4, p. 309, doi. 10.1007/s10585-018-9903-0

By:

Nikolaou, Michail;
Pavlopoulou, Athanasia;
Georgakilas, Alexandros G.;
Kyrodimos, Efthymios

Publication type:

Article

Molecular Biomarkers for Predicting Cancer Patient Radiosensitivity and Radiotoxicity in Clinical Practice.

Published in:

Applied Sciences (2076-3417), 2023, v. 13, n. 23, p. 12564, doi. 10.3390/app132312564

By:

Gkikoudi, Angeliki;
Kalospyros, Spyridon A.;
Triantopoulou, Sotiria;
Logotheti, Stella;
Softa, Vasiliki;
Kappas, Constantin;
Theodorou, Kiki;
Laiakis, Evagelia C.;
Manda, Gina;
Terzoudi, Georgia I.;
Georgakilas, Alexandros G.

Publication type:

Article

Estimation of Cosmic-Ray-Induced Atmospheric Ionization and Radiation at Commercial Aviation Flight Altitudes.

Published in:

Applied Sciences (2076-3417), 2022, v. 12, n. 11, p. 5297, doi. 10.3390/app12115297

By:

Makrantoni, Panagiota;
Tezari, Anastasia;
Stassinakis, Argyris N.;
Paschalis, Pavlos;
Gerontidou, Maria;
Karaiskos, Pantelis;
Georgakilas, Alexandros G.;
Mavromichalaki, Helen;
Usoskin, Ilya G.;
Crosby, Norma;
Dierckxsens, Mark

Publication type:

Article

Non-Targeted Effects of Synchrotron Radiation: Lessons from Experiments at the Australian and European Synchrotrons.

Published in:

Applied Sciences (2076-3417), 2022, v. 12, n. 4, p. 2079, doi. 10.3390/app12042079

By:

Fernandez-Palomo, Cristian;
Nikitaki, Zacharenia;
Djonov, Valentin;
Georgakilas, Alexandros G.;
Martin, Olga A.

Publication type:

Article

Monte Carlo Simulation-Based Calculations of Complex DNA Damage for Incidents of Environmental Ionizing Radiation Exposure.

Published in:

Applied Sciences (2076-3417), 2021, v. 11, n. 19, p. 8985, doi. 10.3390/app11198985

By:

Kalospyros, Spyridon A.;
Gika, Violeta;
Nikitaki, Zacharenia;
Kalamara, Antigoni;
Kyriakou, Ioanna;
Emfietzoglou, Dimitris;
Kokkoris, Michael;
Georgakilas, Alexandros G.

Publication type:

Article

Entropic Ranks: A Methodology for Enhanced, Threshold-Free, Information-Rich Data Partition and Interpretation.

Published in:

Applied Sciences (2076-3417), 2020, v. 10, n. 20, p. 7077, doi. 10.3390/app10207077

By:

de Lastic, Hector-Xavier;
Liampa, Irene;
G. Georgakilas, Alexandros;
Zervakis, Michalis;
Chatziioannou, Aristotelis

Publication type:

Article

Key biological mechanisms involved in high-LET radiation therapies with a focus on DNA damage and repair.

Published in:

Expert Reviews in Molecular Medicine, 2022, v. 24, p. 1, doi. 10.1017/erm.2022.6

By:

Nikitaki, Zacharenia;
Velalopoulou, Anastasia;
Zanni, Vassiliki;
Tremi, Ioanna;
Havaki, Sophia;
Kokkoris, Michael;
Gorgoulis, Vassilis G.;
Koumenis, Constantinos;
Georgakilas, Alexandros G.

Publication type:

Article

Radiation Type- and Dose-Specific Transcriptional Responses across Healthy and Diseased Mammalian Tissues.

Published in:

Antioxidants, 2022, v. 11, n. 11, p. 2286, doi. 10.3390/antiox11112286

By:

Sagkrioti, Eftychia;
Biz, Gökay Mehmet;
Takan, Işıl;
Asfa, Seyedehsadaf;
Nikitaki, Zacharenia;
Zanni, Vassiliki;
Kars, Rumeysa Hanife;
Hellweg, Christine E.;
Azzam, Edouard I.;
Logotheti, Stella;
Pavlopoulou, Athanasia;
Georgakilas, Alexandros G.

Publication type:

Article

A Guide for Using Transmission Electron Microscopy for Studying the Radiosensitizing Effects of Gold Nanoparticles In Vitro.

Published in:

Nanomaterials (2079-4991), 2021, v. 11, n. 4, p. 859, doi. 10.3390/nano11040859

By:

Tremi, Ioanna;
Havaki, Sophia;
Georgitsopoulou, Sofia;
Lagopati, Nefeli;
Georgakilas, Vasilios;
Gorgoulis, Vassilis G.;
Georgakilas, Alexandros G.;
Bardi, Giuseppe

Publication type:

Article

Prediction of Gold Nanoparticle and Microwave-Induced Hyperthermia Effects on Tumor Control via a Simulation Approach.

Published in:

Nanomaterials (2079-4991), 2019, v. 9, n. 2, p. 167, doi. 10.3390/nano9020167

By:

Dimitriou, Nikolaos M.;
Pavlopoulou, Athanasia;
Tremi, Ioanna;
Kouloulias, Vassilis;
Tsigaridas, Georgios;
Georgakilas, Alexandros G.

Publication type:

Article

HOTAIR as a Prognostic Predictor for Diverse Human Cancers: A Meta- and Bioinformatics Analysis.

Published in:

Cancers, 2019, v. 11, n. 6, p. 778, doi. 10.3390/cancers11060778

By:

Toy, Halil Ibrahim;
Okmen, Didem;
Kontou, Panagiota I.;
Georgakilas, Alexandros G.;
Pavlopoulou, Athanasia

Publication type:

Article

Recent Advances in Cancer Therapy Based on Dual Mode Gold Nanoparticles.

Published in:

Cancers, 2017, v. 9, n. 12, p. 173, doi. 10.3390/cancers9120173

By:

Spyratou, Ellas;
Makropoulou, Mersini;
Efstathopoulos, Efstathios P.;
Georgakilas, Alexandros G.;
Sihver, Lembit

Publication type:

Article

Integrative Bioinformatic Analysis of Transcriptomic Data Identifies Conserved Molecular Pathways Underlying Ionizing Radiation-Induced Bystander Effects (RIBE).

Published in:

Cancers, 2017, v. 9, n. 12, p. 160, doi. 10.3390/cancers9120160

By:

Yeles, Constantinos;
Vlachavas, Efstathios-Iason;
Papadodima, Olga;
Pilalis, Eleftherios;
Vorgias, Constantinos E.;
Georgakilas, Alexandros G.;
Chatziioannou, Aristotelis

Publication type:

Article

Complex DNA Damage: A Route to Radiation-Induced Genomic Instability and Carcinogenesis.

Published in:

Cancers, 2017, v. 9, n. 7, p. 91, doi. 10.3390/cancers9070091

By:

Mavragani, Ifigeneia V.;
Nikitaki, Zacharenia;
Souli, Maria P.;
Aziz, Asef;
Nowsheen, Somaira;
Aziz, Khaled;
Rogakou, Emmy;
Georgakilas, Alexandros G.

Publication type:

Article

Bridging Plant and Human Radiation Response and DNA Repair through an In Silico Approach.

Published in:

Cancers, 2017, v. 9, n. 6, p. 65, doi. 10.3390/cancers9060065

By:

Nikitaki, Zacharenia;
Pavlopoulou, Athanasia;
Holá, Marcela;
Donà, Mattia;
Michalopoulos, Ioannis;
Balestrazzi, Alma;
Angelis, Karel J.;
Georgakilas, Alexandros G.

Publication type:

Article

A possible role of repair proteins BRCA1 and DNA-PK in the processing of oxidative DNA damage.

Published in:

Journal of Biochemical Technology, 2010, v. 2, n. 3, p. 9

By:

Georgakilas, Alexandros G.

Publication type:

Article

Correction of anal prolapse associated with resolution of cloacogenic polyp lesions. Implications to anorectal cancer.

Published in:

2008

By:

Kalogerinis, Peter T.;
Morfesis, F. Andrew;
Georgakila, Stavroula;
Georgakilas, Alexandros G.

Publication type:

Case Study

A possible role of repair proteins BRCA1 and DNA-PK in the processing of oxidative DNA damage.

Published in:

Journal of Biochemical Technology, 2008, v. 1, n. 1, p. 9

By:

Georgakilas, Alexandros G.

Publication type:

Article

Modern strategies for photothermal and ionizing radiation therapy based on gold nanoparticles-mediated radiosensitization.

Published in:

Pharmakeftiki, 2017, v. 29, n. 4, p. 83

By:

Spyratou, Ellas;
Makropoulou, Mersini;
Georgakilas, Alexandros G.;
Efstathopoulos, Efstathios P.

Publication type:

Article

Role of Redox Status in Development of Glioblastoma.

Published in:

Frontiers in Immunology, 2016, p. 1, doi. 10.3389/fimmu.2016.00156

By:

Salazar-Ramiro, Aleli;
Ramírez-Ortega, Daniela;
De La Cruz, Verónica Pérez;
Hérnandez-Pedro, Norma Y.;
González-Esquivel, Dinora Fabiola;
Sotelo, Julio;
Pineda, Benjamín;
Simmen, Thomas;
Georgakilas, Alexandros G.

Publication type:

Article

Author Correction: Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.

Published in:

2022

By:

Galanos, Panagiotis;
Pappas, George;
Polyzos, Alexander;
Kotsinas, Athanassios;
Svolaki, Ioanna;
Giakoumakis, Nickolaos N.;
Glytsou, Christina;
Pateras, Ioannis S.;
Swain, Umakanta;
Souliotis, Vassilis L.;
Georgakilas, Alexandros G.;
Geacintov, Nicholas;
Scorrano, Luca;
Lukas, Claudia;
Lukas, Jiri;
Livneh, Zvi;
Lygerou, Zoi;
Chowdhury, Dipanjan;
Sørensen, Claus Storgaard;
Bartek, Jiri

Publication type:

Correction Notice

Induction and Repair of Clustered DNA Lesions: What Do We Know So Far?

Published in:

Radiation Research, 2013, v. 180, n. 1, p. 100, doi. 10.1667/RR3041.1

By:

Georgakilas, Alexandros G.;
O'Neill, Peter;
Stewart, Robert D.

Publication type:

Article

Effects of Radiation Quality and Oxygen on Clustered DNA Lesions and Cell Death.

Published in:

Radiation Research, 2011, v. 176, n. 5, p. 587, doi. 10.1667/RR2663.1

By:

Stewart, Robert D.;
Yu, Victor K.;
Georgakilas, Alexandros G.;
Koumenis, Constantinos;
Park, Joo Han;
Carlson, David J.

Publication type:

Article

Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins.

Published in:

Journal of Cell Biology, 2011, v. 195, n. 7, p. 1123, doi. 10.1083/jcb.201108121

By:

Sideridou, Maria;
Zakopoulou, Roubini;
Evangelou, Konstantinos;
Liontos, Michalis;
Kotsinas, Athanassios;
Rampakakis, Emmanouil;
Gagos, Sarantis;
Kahata, Kaoru;
Grabusic, Kristina;
Gkouskou, Kalliopi;
Trougakos, Ioannis P.;
Kolettas, Evangelos;
Georgakilas, Alexandros G.;
Volarevic, Sinisa;
Eliopoulos, Aristides G.;
Zannis-Hadjopoulos, Maria;
Moustakas, Aristidis;
Gorgoulis, Vassilis G.

Publication type:

Article

Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET).

Published in:

Free Radical Research, 2016, v. 50, p. S64, doi. 10.1080/10715762.2016.1232484

By:

Nikitaki, Zacharenia;
Nikolov, Vladimir;
Mavragani, Ifigeneia V.;
Mladenov, Emil;
Mangelis, Anastasios;
Laskaratou, Danae A.;
Fragkoulis, Georgios I.;
Hellweg, Christine E.;
Martin, Olga A.;
Emfietzoglou, Dimitris;
Hatzi, Vasiliki I.;
Terzoudi, Georgia I.;
Iliakis, George;
Georgakilas, Alexandros G.

Publication type:

Article

DExplore: An Online Tool for Detecting Differentially Expressed Genes from mRNA Microarray Experiments.

Published in:

Biology (2079-7737), 2024, v. 13, n. 5, p. 351, doi. 10.3390/biology13050351

By:

Katsiki, Anna D.;
Karatzas, Pantelis E.;
De Lastic, Hector-Xavier;
Georgakilas, Alexandros G.;
Tsitsilonis, Ourania;
Vorgias, Constantinos E.

Publication type:

Article

Editorial: Metal nanoparticles in cancer: detection, diagnosis, therapy and their pharmacological assessment.

Published in:

Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2023.1344197

By:

Peana, Massimiliano;
Georgakilas, Alexandros G.

Publication type:

Article

Ginger for Healthy Ageing: A Systematic Review on Current Evidence of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties.

Published in:

Oxidative Medicine & Cellular Longevity, 2022, p. 1, doi. 10.1155/2022/4748447

By:

Ozkur, Mehtap;
Benlier, Necla;
Takan, Işıl;
Vasileiou, Christina;
Georgakilas, Alexandros G.;
Pavlopoulou, Athanasia;
Cetin, Zafer;
Saygili, Eyup Ilker

Publication type:

Article

RadPhysBio: A Radiobiological Database for the Prediction of Cell Survival upon Exposure to Ionizing Radiation.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 9, p. 4729, doi. 10.3390/ijms25094729

By:

Zanni, Vassiliki;
Papakonstantinou, Dimitris;
Kalospyros, Spyridon A.;
Karaoulanis, Dimitris;
Biz, Gökay Mehmet;
Manti, Lorenzo;
Adamopoulos, Adam;
Pavlopoulou, Athanasia;
Georgakilas, Alexandros G.

Publication type:

Article

Clustered DNA Damage Patterns after Proton Therapy Beam Irradiation Using Plasmid DNA.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 15606, doi. 10.3390/ijms232415606

By:

Souli, Maria P.;
Nikitaki, Zacharenia;
Puchalska, Monika;
Brabcová, Kateřina Pachnerová;
Spyratou, Ellas;
Kote, Panagiotis;
Efstathopoulos, Efstathios P.;
Hada, Megumi;
Georgakilas, Alexandros G.;
Sihver, Lembit

Publication type:

Article

Effects of High-Dose Ionizing Radiation in Human Gene Expression: A Meta-Analysis.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 6, p. 1938, doi. 10.3390/ijms21061938

By:

Kanakoglou, Dimitrios S.;
Michalettou, Theodora-Dafni;
Vasileiou, Christina;
Gioukakis, Evangelos;
Maneta, Dorothea;
Kyriakidis, Konstantinos V.;
Georgakilas, Alexandros G.;
Michalopoulos, Ioannis

Publication type:

Article