Works matching AU Gennemark, Peter

Results: 31

Benchmarks for identification of ordinary differential equations from time series data.

Published in:

Bioinformatics, 2009, v. 25, n. 6, p. 780, doi. 10.1093/bioinformatics/btp050

By:

Peter Gennemark;
Dag Wedelin

Publication type:

Article

A Simple Mathematical Model of Adaptation to High Osmolarity in Yeast.

Published in:

In Silico Biology, 2006, v. 6, n. 3, p. 193, doi. 10.3233/isb-00233

By:

Gennemark, Peter;
Nordlander, Bodil;
Hohmann, Stefan;
Wedelin, Dag

Publication type:

Article

Inhibition of the prostaglandin D2–GPR44/DP2 axis improves human islet survival and function.

Published in:

Diabetologia, 2020, v. 63, n. 7, p. 1355, doi. 10.1007/s00125-020-05138-z

By:

Abadpour, Shadab;
Tyrberg, Björn;
Schive, Simen W.;
Huldt, Charlotte Wennberg;
Gennemark, Peter;
Ryberg, Erik;
Rydén-Bergsten, Tina;
Smith, David M.;
Korsgren, Olle;
Skrtic, Stanko;
Scholz, Hanne;
Winzell, Maria Sörhede

Publication type:

Article

Systems biology reveals uncoupling beyond UCP1 in human white fat-derived beige adipocytes.

Published in:

NPJ Systems Biology & Applications, 2017, v. 3, n. 1, p. N.PAG, doi. 10.1038/s41540-017-0027-y

By:

Nyman, Elin;
Bartesaghi, Stefano;
Melin Rydfalk, Rebecka;
Eng, Sandra;
Pollard, Charlotte;
Gennemark, Peter;
Peng, Xiao-Rong;
Cedersund, Gunnar

Publication type:

Article

A case‐study of model‐informed drug development of a novel PCSK9 anti sense oligonucleotide. Part 1: First time in man to phase II.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1569, doi. 10.1002/psp4.12866

By:

Knöchel, Jane;
Nilsson, Catarina;
Carlsson, Björn;
Wernevik, Linda;
Hofherr, Alexis;
Gennemark, Peter;
Jansson‐Löfmark, Rasmus;
Isaksson, Rikard;
Rydén‐Bergsten, Tina;
Hamrén, Bengt;
Rekić, Dinko

Publication type:

Article

Model‐Based Analysis Reveals a Sustained and Dose‐Dependent Acceleration of Wound Healing by VEGF‐A mRNA (AZD8601).

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 7, p. 384, doi. 10.1002/psp4.12516

By:

Almquist, Joachim;
Rikard, S. Michaela;
Wågberg, Maria;
Bruce, Anthony C.;
Gennemark, Peter;
Fritsche‐Danielson, Regina;
Chien, Kenneth R.;
Peirce, Shayn M.;
Hansson, Kenny;
Lundahl, Anna

Publication type:

Article

Network modeling of the transcriptional effects of copy number aberrations in glioblastoma.

Published in:

Molecular Systems Biology, 2011, v. 7, n. 1, p. 1, doi. 10.1038/msb.2011.17

By:

Jörnsten, Rebecka;
Abenius, Tobias;
Kling, Teresia;
Schmidt, Linnéa;
Johansson, Erik;
Nordling, Torbjörn E M;
Nordlander, Bodil;
Sander, Chris;
Gennemark, Peter;
Funa, Keiko;
Nilsson, Björn;
Lindahl, Linda;
Nelander, Sven

Publication type:

Article

Models from experiments: combinatorial drug perturbations of cancer cells.

Published in:

Molecular Systems Biology, 2008, v. 4, n. 1, p. 1, doi. 10.1038/msb.2008.53

By:

Nelander, Sven;
Wang, Weiqing;
Nilsson, Björn;
She, Qing‐Bai;
Pratilas, Christine;
Rosen, Neal;
Gennemark, Peter;
Sander, Chris

Publication type:

Article

Effects of a novel potent melanin-concentrating hormone receptor 1 antagonist, AZD1979, on body weight homeostasis in mice and dogs.

Published in:

2016

By:

Ploj, Karolina;
Benthem, Lambertus;
Kakol ‐ Palm, Dorota;
Gennemark, Peter;
Andersson, Liselotte;
Bjursell, Mikael;
Börjesson, Jenny;
Kärrberg, Lillevi;
Månsson, Marianne;
Antonsson, Madeleine;
Johansson, Anders;
Iverson, Suzanne;
Carlsson, Björn;
Turnbull, Andrew;
Lindén, Daniel;
Kakol-Palm, Dorota;
Börjesson, Jenny;
Kärrberg, Lillevi;
Månsson, Marianne;
Carlsson, Björn

Publication type:

journal article

An oral antisense oligonucleotide for PCSK9 inhibition.

Published in:

Science Translational Medicine, 2021, v. 13, n. 593, p. 1, doi. 10.1126/scitranslmed.abe9117

By:

Gennemark, Peter;
Walter, Katrin;
Clemmensen, Niclas;
Rekić, Dinko;
Nilsson, Catarina A.M.;
Knöchel, Jane;
Hölttä, Mikko;
Wernevik, Linda;
Rosengren, Birgitta;
Kakol-Palm, Dorota;
Wang, Yanfeng;
Yu, Rosie Z.;
Geary, Richard S.;
Riney, Stan J.;
Monia, Brett P.;
Isaksson, Rikard;
Jansson-Löfmark, Rasmus;
Rocha, Cristina S. J.;
Lindén, Daniel;
Hurt-Camejo, Eva

Publication type:

Article

Mathematical Model Predicts that Acceleration of Diabetic Wound Healing is Dependent on Spatial Distribution of VEGF-A mRNA (AZD8601).

Published in:

Cellular & Molecular Bioengineering, 2021, v. 14, n. 4, p. 321, doi. 10.1007/s12195-021-00678-9

By:

Rikard, S. Michaela;
Myers, Paul J.;
Almquist, Joachim;
Gennemark, Peter;
Bruce, Anthony C.;
Wågberg, Maria;
Fritsche-Danielson, Regina;
Hansson, Kenny M.;
Lazzara, Matthew J.;
Peirce, Shayn M.

Publication type:

Article

Input estimation for drug discovery using optimal control and Markov chain Monte Carlo approaches.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2016, v. 43, n. 2, p. 207, doi. 10.1007/s10928-016-9467-z

By:

Trägårdh, Magnus;
Chappell, Michael;
Ahnmark, Andrea;
Lindén, Daniel;
Evans, Neil;
Gennemark, Peter

Publication type:

Article

Modeling energy intake by adding homeostatic feedback and drug intervention.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2015, v. 42, n. 1, p. 79, doi. 10.1007/s10928-014-9399-4

By:

Gennemark, Peter;
Hjorth, Stephan;
Gabrielsson, Johan

Publication type:

Article

A modeling approach for compounds affecting body composition.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2013, v. 40, n. 6, p. 651, doi. 10.1007/s10928-013-9337-x

By:

Gennemark, Peter;
Jansson-Löfmark, Rasmus;
Hyberg, Gina;
Wigstrand, Maria;
Kakol-Palm, Dorota;
Håkansson, Pernilla;
Hovdal, Daniel;
Brodin, Peter;
Fritsch-Fredin, Maria;
Antonsson, Madeleine;
Ploj, Karolina;
Gabrielsson, Johan

Publication type:

Article

Population pharmacokinetic modeling and deconvolution of enantioselective absorption of eflornithine in the rat.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2013, v. 40, n. 1, p. 117, doi. 10.1007/s10928-012-9293-x

By:

Johansson, Carl-Christer;
Gennemark, Peter;
Artursson, Per;
Äbelö, Angela;
Ashton, Michael;
Jansson-Löfmark, Rasmus

Publication type:

Article

Normoglycemia and physiological cortisone level maintain glucose homeostasis in a pancreas-liver microphysiological system.

Published in:

Communications Biology, 2024, p. 1, doi. 10.1038/s42003-024-06514-w

By:

Rigal, Sophie;
Casas, Belén;
Kanebratt, Kajsa P.;
Wennberg Huldt, Charlotte;
Magnusson, Lisa U.;
Müllers, Erik;
Karlsson, Fredrik;
Clausen, Maryam;
Hansson, Sara F.;
Leonard, Louise;
Cairns, Jonathan;
Jansson Löfmark, Rasmus;
Ämmälä, Carina;
Marx, Uwe;
Gennemark, Peter;
Cedersund, Gunnar;
Andersson, Tommy B.;
Vilén, Liisa K.

Publication type:

Article

Corrigendum: Integrative model of the response of yeast to osmotic shock.

Published in:

2006

By:

Klipp, Edda;
Nordlander, Bodil;
Krüger, Roland;
Gennemark, Peter;
Hohmann, Stefan

Publication type:

Erratum

Integrative model of the response of yeast to osmotic shock.

Published in:

Nature Biotechnology, 2005, v. 23, n. 8, p. 975, doi. 10.1038/nbt1114

By:

Klipp, Edda;
Nordlander, Bodil;
Krüger, Roland;
Gennemark, Peter;
Hohmann, Stefan

Publication type:

Article

Inhibition of SGLT2 Preserves Function and Promotes Proliferation of Human Islets Cells In Vivo in Diabetic Mice.

Published in:

Biomedicines, 2022, v. 10, n. 2, p. 203, doi. 10.3390/biomedicines10020203

By:

Karlsson, Daniel;
Ahnmark, Andrea;
Sabirsh, Alan;
Andréasson, Anne-Christine;
Gennemark, Peter;
Sandinge, Ann-Sofie;
Chen, Lihua;
Tyrberg, Björn;
Lindén, Daniel;
Sörhede Winzell, Maria

Publication type:

Article

3D cell aggregates amplify diffusion signals.

Published in:

PLoS ONE, 2024, v. 19, n. 9, p. 1, doi. 10.1371/journal.pone.0310109

By:

Arjmandi, Hamidreza;
Kanebratt, Kajsa P.;
Vilén, Liisa;
Gennemark, Peter;
Noel, Adam

Publication type:

Article

Optimal Design in Population Kinetic Experiments by Set-Valued Methods.

Published in:

AAPS Journal, 2011, v. 13, n. 4, p. 495, doi. 10.1208/s12248-011-9291-8

By:

Gennemark, Peter;
Danis, Alexander;
Nyberg, Joakim;
Hooker, Andrew;
Tucker, Warwick

Publication type:

Article

Deficiency of T-type voltage-gated calcium channels results in attenuated weight gain and improved endothelium-dependent dilatation of resistance vessels induced by a high-fat diet in mice.

Published in:

Journal of Physiology & Biochemistry, 2020, v. 76, n. 1, p. 135, doi. 10.1007/s13105-020-00728-2

By:

Rosenstand, Kristoffer;
Andersen, Kenneth;
Terp, Rasmus;
Gennemark, Peter;
Ellman, Ditte Gry;
Reznichenko, Anna;
Lambertsen, Kate Lykke;
Vanhoutte, Paul M.;
Hansen, Pernille B. L.;
Svenningsen, Per

Publication type:

Article

Unlock the Thermogenic Potential of Adipose Tissue: Pharmacological Modulation and implications for Treatment of Diabetes and Obesity.

Published in:

Frontiers in Endocrinology, 2015, v. 6, p. 1, doi. 10.3389/fendo.2015.00174

By:

Xiao-Rong Peng;
Gennemark, Peter;
O'Mahony, Gavin;
Bartesaghi, Stefano;
Bin Xu;
Qin Yang

Publication type:

Article

Integrated experimental-computational analysis of a HepaRG liver-islet microphysiological system for human-centric diabetes research.

Published in:

PLoS Computational Biology, 2022, v. 18, n. 10, p. 1, doi. 10.1371/journal.pcbi.1010587

By:

Casas, Belén;
Vilén, Liisa;
Bauer, Sophie;
Kanebratt, Kajsa P.;
Wennberg Huldt, Charlotte;
Magnusson, Lisa;
Marx, Uwe;
Andersson, Tommy B.;
Gennemark, Peter;
Cedersund, Gunnar

Publication type:

Article

Digital twin predicting diet response before and after long-term fasting.

Published in:

PLoS Computational Biology, 2022, v. 18, n. 9, p. 1, doi. 10.1371/journal.pcbi.1010469

By:

Silfvergren, Oscar;
Simonsson, Christian;
Ekstedt, Mattias;
Lundberg, Peter;
Gennemark, Peter;
Cedersund, Gunnar

Publication type:

Article

1953-P: PPARγ Agonism and FGF-21 Synergize to Robustly Induce Browning of White Fat.

Published in:

Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1953-P

By:

KROON, TOBIAS;
HARMS, MATTHEW J.;
NILSSON, DANIEL;
LINDBLOM, ANNA;
GENNEMARK, PETER;
O'MAHONY, GAVIN;
OSINSKI, VICTORIA;
MCNAMARA, COLEEN A.;
BOUCHER, JEREMIE

Publication type:

Article

A multi-scale digital twin for adiposity-driven insulin resistance in humans: diet and drug effects.

Published in:

Diabetology & Metabolic Syndrome, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13098-023-01223-6

By:

Herrgårdh, Tilda;
Simonsson, Christian;
Ekstedt, Mattias;
Lundberg, Peter;
Stenkula, Karin G.;
Nyman, Elin;
Gennemark, Peter;
Cedersund, Gunnar

Publication type:

Article

Automated analysis of routinely generated preclinical pharmacokinetic and pharmacodynamic data.

Published in:

Journal of Bioinformatics & Computational Biology, 2014, v. 12, n. 3, p. 1450010-1, doi. 10.1142/S0219720014500103

By:

Lindhardt, Emma;
Gennemark, Peter

Publication type:

Article

ODEion - A SOFTWARE MODULE FOR STRUCTURAL IDENTIFICATION OF ORDINARY DIFFERENTIAL EQUATIONS.

Published in:

Journal of Bioinformatics & Computational Biology, 2014, v. 12, n. 1, p. -1, doi. 10.1142/S0219720013500157

By:

GENNEMARK, PETER;
WEDELIN, DAG

Publication type:

Article

MODELING YEAST OSMOADAPTATION AT DIFFERENT LEVELS OF RESOLUTION.

Published in:

Journal of Bioinformatics & Computational Biology, 2013, v. 11, n. 2, p. 1, doi. 10.1142/S0219720013300013

By:

KÜHN, CLEMENS;
GENNEMARK, PETER

Publication type:

Article

Plasma Pharmacokinetics of N-Acetylgalactosamine-Conjugated Small-Interfering Ribonucleic Acids (GalNAc-Conjugated siRNAs).

Published in:

Clinical Pharmacokinetics, 2023, v. 62, n. 12, p. 1661, doi. 10.1007/s40262-023-01314-7

By:

Sten, Sebastian;
Cardilin, Tim;
Antonsson, Madeleine;
Gennemark, Peter

Publication type:

Article