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Low‐Dose Chemotherapy Preferentially Shapes the Ileal Microbiome and Augments the Response to Immune Checkpoint Blockade by Activating AIM2 Inflammasome in Ileal Epithelial Cells.
- Published in:
- Advanced Science, 2024, v. 11, n. 11, p. 1, doi. 10.1002/advs.202304781
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- Publication type:
- Article
A novel strategy for treating oncogene‐mutated tumors by targeting tumor microenvironment and synergistically enhancing anti‐PD‐1 immunotherapy.
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- Cancer Communications, 2024, v. 44, n. 3, p. 438, doi. 10.1002/cac2.12521
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- Publication type:
- Article
A novel STING agonist with systemic and durable anti-tumour activity.
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- Clinical & Translational Discovery, 2023, v. 3, n. 5, p. 1, doi. 10.1002/ctd2.231
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- Article
Correction: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance.
- Published in:
- 2023
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- Publication type:
- Correction Notice
SYK-mediated epithelial cell state is associated with response to c-Met inhibitors in c-Met-overexpressing lung cancer.
- Published in:
- Signal Transduction & Targeted Therapy, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41392-023-01403-w
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- Publication type:
- Article
SYK-mediated epithelial cell state is associated with response to c-Met inhibitors in c-Met-overexpressing lung cancer.
- Published in:
- Signal Transduction & Targeted Therapy, 2023, p. 1, doi. 10.1038/s41392-023-01403-w
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- Publication type:
- Article
SYK-mediated epithelial cell state is associated with response to c-Met inhibitors in c-Met-overexpressing lung cancer.
- Published in:
- Signal Transduction & Targeted Therapy, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41392-023-01403-w
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- Publication type:
- Article
Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo.
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- Journal of Cancer, 2023, v. 14, n. 1, p. 152, doi. 10.7150/jca.77788
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- Publication type:
- Article
Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation.
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- Cell Discovery, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41421-022-00481-4
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- Article
Development of a novel lactate dehydrogenase A inhibitor with potent antitumor activity and immune activation.
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- Cancer Science, 2022, v. 113, n. 9, p. 2974, doi. 10.1111/cas.15468
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- Publication type:
- Article
Chronic Kidney Disease and Cognitive Impairment: The Kidney-Brain Axis.
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- Kidney Diseases, 2022, v. 8, n. 4, p. 275, doi. 10.1159/000524475
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- Publication type:
- Article
HER2/PD1 bispecific antibody in IgG4 subclass with superior anti‐tumour activities.
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- Clinical & Translational Medicine, 2022, v. 12, n. 4, p. 1, doi. 10.1002/ctm2.791
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- Publication type:
- Article
LS‐106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo.
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- Cancer Science, 2022, v. 113, n. 2, p. 709, doi. 10.1111/cas.15229
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- Publication type:
- Article
Integrative host microbiota multi‐omics analysis reveals distinctive systemic inflammation and metabolic disorder across Alzheimer's disease continuum.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.055865
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- Publication type:
- Article
Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance.
- Published in:
- 2021
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- Publication type:
- Correction Notice
Causal communication between gut microbiota dysbiosis and neuroinflammation in Alzheimer's disease and therapeutic intervention by oligomannate: Microbiome in Alzheimer's disease: Pathogenesis and treatment implications.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044151
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- Publication type:
- Article
Correction: Undecylprodigiosin Induced Apoptosis in P388 Cancer Cells Is Associated with Its Binding to Ribosome.
- Published in:
- 2020
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- Publication type:
- Correction Notice
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance.
- Published in:
- Molecular Cancer, 2020, v. 19, n. 1, p. 1, doi. 10.1186/s12943-020-01202-9
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- Publication type:
- Article
Preclinical evaluation of 3D185, a novel potent inhibitor of FGFR1/2/3 and CSF-1R, in FGFR-dependent and macrophage-dominant cancer models.
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2019, v. 38, n. 1, p. N.PAG, doi. 10.1186/s13046-019-1357-y
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- Article
p53 β-hydroxybutyrylation attenuates p53 activity.
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- Cell Death & Disease, 2019, v. 10, n. 3, p. 1, doi. 10.1038/s41419-019-1463-y
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- Publication type:
- Article
China's reform of the regulatory system for medical products and its impact.
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- National Science Review, 2019, v. 6, n. 1, p. 1, doi. 10.1093/nsr/nwz001
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- Article
Alzheimer's disease hypothesis and related therapies.
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- Translational Neurodegeneration, 2018, v. 7, p. 1, doi. 10.1186/s40035-018-0107-y
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- Publication type:
- Article
Targeting sphingosine-1-phosphate signaling for cancer therapy.
- Published in:
- SCIENCE CHINA Life Sciences, 2017, v. 60, n. 6, p. 585, doi. 10.1007/s11427-017-9046-6
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- Article
Identification of Epigallocatechin-3- Gallate as an Inhibitor of Phosphoglycerate Mutase 1.
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- Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00325
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- Publication type:
- Article
Exploiting histone deacetylases for cancer therapy: from hematological malignancies to solid tumors.
- Published in:
- SCIENCE CHINA Life Sciences, 2017, v. 60, n. 1, p. 94, doi. 10.1007/s11427-016-0300-y
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- Publication type:
- Article
Design, Synthesis and Biological Evaluation of 6-(2,6-Dichloro-3,5-dimethoxyphenyl)- 4-substituted-1H-indazoles as Potent Fibroblast Growth Factor Receptor Inhibitors.
- Published in:
- Molecules, 2016, v. 21, n. 10, p. 1407, doi. 10.3390/molecules21101407
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- Publication type:
- Article
Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets.
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- Scientific Reports, 2015, p. 1, doi. 10.1038/srep14739
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- Publication type:
- Article
Lactate Dehydrogenase B Is Associated with the Response to Neoadjuvant Chemotherapy in Oral Squamous Cell Carcinoma.
- Published in:
- PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0125976
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- Publication type:
- Article
Featured Article: Teriflunomide, an immunomodulatory drug, exerts anticancer activity in triple negative breast cancer cells.
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- Experimental Biology & Medicine, 2015, v. 240, n. 4, p. 426, doi. 10.1177/1535370214554881
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- Publication type:
- Article
Discovery of Novel c-Met Inhibitors Bearing a 3-Carboxyl Piperidin-2-one Scaffold.
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- Molecules, 2014, v. 19, n. 2, p. 2655, doi. 10.3390/molecules19022655
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- Publication type:
- Article
Monocarboxylate Transporter 4 Facilitates Cell Proliferation and Migration and Is Associated with Poor Prognosis in Oral Squamous Cell Carcinoma Patients.
- Published in:
- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0087904
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- Publication type:
- Article
Luminal Breast Cancer Cell Lines Overexpressing ZNF703 Are Resistant to Tamoxifen through Activation of Akt/mTOR Signaling.
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- PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072053
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- Publication type:
- Article
Undecylprodigiosin Induced Apoptosis in P388 Cancer Cells Is Associated with Its Binding to Ribosome.
- Published in:
- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0065381
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- Publication type:
- Article
Curcumin Induces Cell Death and Restores Tamoxifen Sensitivity in the Antiestrogen-Resistant Breast Cancer Cell Lines MCF-7/LCC2 and MCF-7/LCC9.
- Published in:
- Molecules, 2013, v. 18, n. 1, p. 701, doi. 10.3390/molecules18010701
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- Publication type:
- Article
AL3810, a multi-tyrosine kinase inhibitor, exhibits potent anti-angiogenic and anti-tumour activity via targeting VEGFR, FGFR and PDGFR.
- Published in:
- Journal of Cellular & Molecular Medicine, 2012, v. 16, n. 10, p. 2321, doi. 10.1111/j.1582-4934.2012.01541.x
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- Publication type:
- Article
Evaluation of the cytotoxic activity of new jadomycin derivatives reveals the potential to improve its selectivity against tumor cells.
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- Journal of Antibiotics, 2012, v. 65, n. 9, p. 449, doi. 10.1038/ja.2012.48
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- Article
O-Linked Triazolotriazines: Potent and Selective c-Met Inhibitors.
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- ChemMedChem, 2012, v. 7, n. 7, p. 1276, doi. 10.1002/cmdc.201200145
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- Publication type:
- Article
Discovery of 3 H-Imidazo[4,5- b]pyridines as Potent c-Met Kinase Inhibitors: Design, Synthesis, and Biological Evaluation.
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- ChemMedChem, 2012, v. 7, n. 6, p. 1057, doi. 10.1002/cmdc.201200120
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- Article
Back Cover: Discovery of 3 H-Imidazo[4,5- b]pyridines as Potent c-Met Kinase Inhibitors: Design, Synthesis, and Biological Evaluation (ChemMedChem 6/2012).
- Published in:
- ChemMedChem, 2012, v. 7, n. 6, p. 1129, doi. 10.1002/cmdc.201290028
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- Publication type:
- Article
Extensive Crosstalk between O-GlcNAcylation and Phosphorylation Regulates Akt Signaling.
- Published in:
- PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037427
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- Publication type:
- Article
Oligomannurarate sulfate sensitizes cancer cells to doxorubicin by inhibiting atypical activation of NF- κB via targeting of Mre11.
- Published in:
- International Journal of Cancer, 2012, v. 130, n. 2, p. 467, doi. 10.1002/ijc.26021
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- Publication type:
- Article
Design and Synthesis of a Series of Novel Bisquinazoline Glycosides as Epidermal Growth Factor Receptor Inhibitors.
- Published in:
- Chemical Biology & Drug Design, 2011, v. 78, n. 6, p. 1006, doi. 10.1111/j.1747-0285.2011.01209.x
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- Publication type:
- Article
The Role of Polymeric Immunoglobulin Receptor in Inflammation-Induced Tumor Metastasis of Human Hepatocellular Carcinoma.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2011, v. 103, n. 22, p. 1696, doi. 10.1093/jnci/djr360
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- Publication type:
- Article
D11, a novel glycosylated diphyllin derivative, exhibits potent anticancer activity by targeting topoisomerase IIα.
- Published in:
- Investigational New Drugs, 2011, v. 29, n. 5, p. 800, doi. 10.1007/s10637-010-9425-3
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- Publication type:
- Article
D11, a novel glycosylated diphyllin derivative, exhibits potent anticancer activity by targeting topoisomerase II[alpha].
- Published in:
- 2011
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- Publication type:
- Journal Article
AST1306, A Novel Irreversible Inhibitor of the Epidermal Growth Factor Receptor 1 and 2, Exhibits Antitumor Activity Both In Vitro and In Vivo.
- Published in:
- PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0021487
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- Publication type:
- Article
The role of histone deacetylase 7 (HDAC7) in cancer cell proliferation: regulation on c-Myc.
- Published in:
- Journal of Molecular Medicine, 2011, v. 89, n. 3, p. 279, doi. 10.1007/s00109-010-0701-7
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- Publication type:
- Article
Aspergiolides C and D: Spirocyclic Aromatic Polyketides with Potent Protein Kinase c-Met Inhibitory Effects.
- Published in:
- Chemistry - A European Journal, 2011, v. 17, n. 4, p. 1319, doi. 10.1002/chem.201001547
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- Publication type:
- Article
The glycan profile of endothelial cells in the present of tumor-conditioned medium and potential roles of β-1,6-GlcNAc branching on HUVEC conformation.
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- Molecular & Cellular Biochemistry, 2010, v. 340, n. 1/2, p. 143, doi. 10.1007/s11010-010-0411-z
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- Publication type:
- Article
Novel Conjugates of Aspirin with Phenolic Acid as Anti-inflammatory Agents Having Significantly Reduced Gastrointestinal Toxicity.
- Published in:
- Archiv der Pharmazie, 2010, v. 343, n. 4, p. 215, doi. 10.1002/ardp.200900217
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- Publication type:
- Article