Works matching AU Gaunt, Tom R.


Results: 128
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    Transcriptome-wide Mendelian randomization during CD4<sup>+</sup> T cell activation reveals immune-related drug targets for cardiometabolic diseases.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53621-7
    By:
    • Wu, Xueyan;
    • Ying, Hui;
    • Yang, Qianqian;
    • Yang, Qian;
    • Liu, Haoyu;
    • Ding, Yilan;
    • Zhao, Huiling;
    • Chen, Zhihe;
    • Zheng, Ruizhi;
    • Lin, Hong;
    • Wang, Shuangyuan;
    • Li, Mian;
    • Wang, Tiange;
    • Zhao, Zhiyun;
    • Xu, Min;
    • Chen, Yuhong;
    • Xu, Yu;
    • Vincent, Emma E.;
    • Borges, Maria Carolina;
    • Gaunt, Tom R.
    Publication type:
    Article
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    Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies.

    Published in:
    European Heart Journal, 2013, v. 34, n. 13, p. 972, doi. 10.1093/eurheartj/ehs243
    By:
    • Shah, Sonia;
    • Casas, Juan P.;
    • Gaunt, Tom R.;
    • Cooper, Jackie;
    • Drenos, Fotios;
    • Zabaneh, Delilah;
    • Swerdlow, Daniel I.;
    • Shah, Tina;
    • Sofat, Reecha;
    • Palmen, Jutta;
    • Kumari, Meena;
    • Kivimaki, Mika;
    • Ebrahim, Shah;
    • Smith, George Davey;
    • Lawlor, Debbie A.;
    • Talmud, Philippa J.;
    • Whittaker, John;
    • Day, Ian N.M.;
    • Hingorani, Aroon D.;
    • Humphries, Steve E.
    Publication type:
    Article
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    Validation of lipid-related therapeutic targets for coronary heart disease prevention using human genetics.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25731-z
    By:
    • Gordillo-Marañón, María;
    • Zwierzyna, Magdalena;
    • Charoen, Pimphen;
    • Drenos, Fotios;
    • Chopade, Sandesh;
    • Shah, Tina;
    • Engmann, Jorgen;
    • Chaturvedi, Nishi;
    • Papacosta, Olia;
    • Wannamethee, Goya;
    • Wong, Andrew;
    • Sofat, Reecha;
    • Kivimaki, Mika;
    • Price, Jackie F.;
    • Hughes, Alun D.;
    • Gaunt, Tom R.;
    • Lawlor, Deborah A.;
    • Gaulton, Anna;
    • Hingorani, Aroon D.;
    • Schmidt, Amand F.
    Publication type:
    Article
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    Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25703-3
    By:
    • Schmidt, Amand F.;
    • Hunt, Nicholas B.;
    • Gordillo-Marañón, Maria;
    • Charoen, Pimphen;
    • Drenos, Fotios;
    • Kivimaki, Mika;
    • Lawlor, Deborah A.;
    • Giambartolomei, Claudia;
    • Papacosta, Olia;
    • Chaturvedi, Nishi;
    • Bis, Joshua C.;
    • O'Donnell, Christopher J.;
    • Wannamethee, Goya;
    • Wong, Andrew;
    • Price, Jackie F.;
    • Hughes, Alun D.;
    • Gaunt, Tom R.;
    • Franceschini, Nora;
    • Mook-Kanamori, Dennis O.;
    • Zwierzyna, Magdalena
    Publication type:
    Article
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    Genetic Variants Associated with von Willebrand Factor Levels in Healthy Men and Women Identified Using the HumanCVD BeadChip.

    Published in:
    Annals of Human Genetics, 2011, v. 75, n. 4, p. 456, doi. 10.1111/j.1469-1809.2011.00654.x
    By:
    • Zabaneh, Delilah;
    • Gaunt, Tom R.;
    • Kumari, Meena;
    • Drenos, Fotios;
    • Shah, Sonia;
    • Berry, Diane;
    • Power, Chris;
    • Hypponen, Elina;
    • Shah, Tina;
    • Palmen, Jutta;
    • Pallas, Jacky;
    • Talmud, Philippa J.;
    • Casas, Juan Pablo;
    • Sofat, Reecha;
    • Lowe, Gordon;
    • Rumley, Ann;
    • Morris, Richard W.;
    • Whincup, Peter H.;
    • Rodriguez, Santiago;
    • Ebrahim, Shah
    Publication type:
    Article
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    Circulating Fatty Acids and Risk of Coronary Heart Disease and Stroke: Individual Participant Data Meta-Analysis in Up to 16 126 Participants.

    Published in:
    2020
    By:
    • Borges, Maria Carolina;
    • Schmidt, Amand Floriaan;
    • Jefferis, Barbara;
    • Wannamethee, S. Goya;
    • Lawlor, Debbie A.;
    • Kivimaki, Mika;
    • Kumari, Meena;
    • Gaunt, Tom R.;
    • Ben-Shlomo, Yoav;
    • Tillin, Therese;
    • Menon, Usha;
    • Providencia, Rui;
    • Dale, Caroline;
    • Gentry-Maharaj, Aleksandra;
    • Hughes, Alun;
    • Chaturvedi, Nish;
    • Casas, Juan Pablo;
    • Hingorani, Aroon D.;
    • UCLEB Consortium**
    Publication type:
    journal article
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    impact of fatty acids biosynthesis on the risk of cardiovascular diseases in Europeans and East Asians: a Mendelian randomization study.

    Published in:
    Human Molecular Genetics, 2022, v. 31, n. 23, p. 4034, doi. 10.1093/hmg/ddac153
    By:
    • Borges, Maria-Carolina;
    • Haycock, Phillip;
    • Zheng, Jie;
    • Hemani, Gibran;
    • Howe, Laurence J;
    • Schmidt, A Floriaan;
    • Staley, James R;
    • Lumbers, R Thomas;
    • Henry, Albert;
    • Lemaitre, Rozenn N;
    • Gaunt, Tom R;
    • Holmes, Michael V;
    • Smith, George Davey;
    • Hingorani, Aroon D;
    • Lawlor, Deborah A
    Publication type:
    Article
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    Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence.

    Published in:
    Human Molecular Genetics, 2021, v. 30, n. 1, p. 119, doi. 10.1093/hmg/ddaa280
    By:
    • Mulder, Rosa H;
    • Neumann, Alexander;
    • Cecil, Charlotte A M;
    • Walton, Esther;
    • Houtepen, Lotte C;
    • Simpkin, Andrew J;
    • Rijlaarsdam, Jolien;
    • Heijmans, Bastiaan T;
    • Gaunt, Tom R;
    • Felix, Janine F;
    • Jaddoe, Vincent W V;
    • Bakermans-Kranenburg, Marian J;
    • Tiemeier, Henning;
    • Relton, Caroline L;
    • IJzendoorn, Marinus H van;
    • Suderman, Matthew
    Publication type:
    Article
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    Replication and Characterization of Association between ABO SNPs and Red Blood Cell Traits by Meta-Analysis in Europeans.

    Published in:
    PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0156914
    By:
    • McLachlan, Stela;
    • Giambartolomei, Claudia;
    • White, Jon;
    • Charoen, Pimphen;
    • Wong, Andrew;
    • Finan, Chris;
    • Engmann, Jorgen;
    • Shah, Tina;
    • Hersch, Micha;
    • Podmore, Clara;
    • Cavadino, Alana;
    • Jefferis, Barbara J.;
    • Dale, Caroline E.;
    • Hypponen, Elina;
    • Morris, Richard W.;
    • Casas, Juan P.;
    • Kumari, Meena;
    • Ben-Shlomo, Yoav;
    • Gaunt, Tom R.;
    • Drenos, Fotios
    Publication type:
    Article
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    Inflammation-related epigenetic risk and child and adolescent mental health: A prospective study from pregnancy to middle adolescence.

    Published in:
    Development & Psychopathology, 2018, v. 30, n. 3, p. 1145, doi. 10.1017/S0954579418000330
    By:
    • Doyle, Colleen;
    • Cicchetti, Dante;
    • Barker, Edward D.;
    • Cecil, Charlotte A. M.;
    • Walton, Esther;
    • Houtepen, Lotte C.;
    • O'Connor, Thomas G.;
    • Danese, Andrea;
    • Jaffee, Sara R.;
    • Jensen, Sarah K. G.;
    • Pariante, Carmine;
    • McArdle, Wendy;
    • Gaunt, Tom R.;
    • Relton, Caroline L.;
    • Roberts, Susanna
    Publication type:
    Article
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    A proteome- wide genetic investigation identifies several SARS- CoV-2- exploited host targets of clinical relevance.

    Published in:
    eLife, 2021, p. 1, doi. 10.7554/eLife.69719
    By:
    • Anisul, Mohd;
    • Shilts, Jarrod;
    • Schwartzentruber, Jeremy;
    • Hayhurst, James;
    • Buniello, Annalisa;
    • Mohammed, Elmutaz Shaikho Elhaj;
    • Zheng, Jie;
    • Holmes, Michael;
    • Ochoa, David;
    • Carmona, Miguel;
    • Maranville, Joseph;
    • Gaunt, Tom R.;
    • Emilsson, Valur;
    • Gudnason, Vilmundur;
    • McDonagh, Ellen M.;
    • Wright, Gavin J.;
    • Ghoussaini, Maya;
    • Dunham, Ian
    Publication type:
    Article
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    The causal effects of serum lipids and apolipoproteins on kidney function: multivariable and bidirectional Mendelian-randomization analyses.

    Published in:
    2021
    By:
    • Rasheed, Humaira;
    • Zheng, Jie;
    • Rees, Jessica;
    • Sanderson, Eleanor;
    • Thomas, Laurent;
    • Richardson, Tom G;
    • Fang, Si;
    • Bekkevold, Ole-Jørgen;
    • Stovner, Endre Bakken;
    • Gabrielsen, Maiken Elvestad;
    • Skogholt, Anne Heidi;
    • Romundstad, Solfrid;
    • Brumpton, Ben;
    • Hallan, Stein;
    • Willer, Cristen;
    • Burgess, Stephen;
    • Hveem, Kristian;
    • Smith, George Davey;
    • Gaunt, Tom R;
    • Åsvold, Bjørn Olav
    Publication type:
    journal article
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    Appraising the causal relevance of DNA methylation for risk of lung cancer.

    Published in:
    2019
    By:
    • Battram, Thomas;
    • Richmond, Rebecca C;
    • Baglietto, Laura;
    • Haycock, Philip C;
    • Perduca, Vittorio;
    • Bojesen, Stig E;
    • Gaunt, Tom R;
    • Hemani, Gibran;
    • Guida, Florence;
    • Carreras-Torres, Robert;
    • Hung, Rayjean;
    • Amos, Christopher I;
    • Freeman, Joshua R;
    • Sandanger, Torkjel M;
    • Nøst, Therese H;
    • Nordestgaard, Børge G;
    • Teschendorff, Andrew E;
    • Polidoro, Silvia;
    • Vineis, Paolo;
    • Severi, Gianluca
    Publication type:
    journal article