Works matching AU Gasparello, Jessica

Results: 39

Expression of γ-globin genes in β-thalassemia patients treated with sirolimus: results from a pilot clinical trial (Sirthalaclin).

Published in:

Therapeutic Advances in Hematology, 2022, v. 13, p. 1, doi. 10.1177/20406207221100648

By:

Zuccato, Cristina;
Cosenza, Lucia Carmela;
Zurlo, Matteo;
Gasparello, Jessica;
Papi, Chiara;
D'Aversa, Elisabetta;
Breveglieri, Giulia;
Lampronti, Ilaria;
Finotti, Alessia;
Borgatti, Monica;
Scapoli, Chiara;
Stievano, Alice;
Fortini, Monica;
Ramazzotti, Eric;
Marchetti, Nicola;
Prosdocimi, Marco;
Gamberini, Maria Rita;
Gambari, Roberto

Publication type:

Article

MicroRNAs miR-584-5p and miR-425-3p Are Up-Regulated in Plasma of Colorectal Cancer (CRC) Patients: Targeting with Inhibitor Peptide Nucleic Acids Is Associated with Induction of Apoptosis in Colon Cancer Cell Lines.

Published in:

Cancers, 2023, v. 15, n. 1, p. 128, doi. 10.3390/cancers15010128

By:

Gasparello, Jessica;
Papi, Chiara;
Zurlo, Matteo;
Gambari, Laura;
Manicardi, Alex;
Rozzi, Andrea;
Ferrarini, Matteo;
Corradini, Roberto;
Gambari, Roberto;
Finotti, Alessia

Publication type:

Article

A Distinctive microRNA (miRNA) Signature in the Blood of Colorectal Cancer (CRC) Patients at Surgery.

Published in:

Cancers, 2020, v. 12, n. 9, p. 2410, doi. 10.3390/cancers12092410

By:

Gasparello, Jessica;
Papi, Chiara;
Allegretti, Matteo;
Giordani, Elena;
Carboni, Fabio;
Zazza, Settimio;
Pescarmona, Edoardo;
Romania, Paolo;
Giacomini, Patrizio;
Scapoli, Chiara;
Gambari, Roberto;
Finotti, Alessia

Publication type:

Article

HER2 expression and genOmic characterization of rESected brain metastases from colorectal cancer: the HEROES study.

Published in:

British Journal of Cancer, 2024, v. 130, n. 8, p. 1316, doi. 10.1038/s41416-023-02569-4

By:

Prete, Alessandra Anna;
Angerilli, Valentina;
Bergamo, Francesca;
Vettore, Valentina;
De Toni, Chiara;
Intini, Rossana;
Cerma, Krisida;
Ricagno, Gianmarco;
Cerantola, Riccardo;
Perissinotto, Eleonora;
De Rosa, Antonio;
Ceccon, Carlotta;
Gasparello, Jessica;
Denaro, Luca;
D'Amico, Alberto;
Chioffi, Franco;
Carcea, Elena;
Fassan, Matteo;
Lonardi, Sara

Publication type:

Article

Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA).

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2018, v. 37, n. 1, p. N.PAG, doi. 10.1186/s13046-018-0788-1

By:

Gasparello, Jessica;
Allegretti, Matteo;
Tremante, Elisa;
Fabbri, Enrica;
Amoreo, Carla Azzurra;
Romania, Paolo;
Melucci, Elisa;
Messana, Katia;
Borgatti, Monica;
Giacomini, Patrizio;
Gambari, Roberto;
Finotti, Alessia

Publication type:

Article

Chemical-Induced Read-Through at Premature Termination Codons Determined by a Rapid Dual-Fluorescence System Based on S. cerevisiae.

Published in:

PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0154260

By:

Altamura, Emiliano;
Borgatti, Monica;
Finotti, Alessia;
Gasparello, Jessica;
Gambari, Roberto;
Spinelli, Mariangela;
Castaldo, Rosa;
Altamura, Nicola

Publication type:

Article

Effects of Sulforaphane on SARS-CoV-2 infection and NF-κB dependent expression of genes involved in the COVID-19 'cytokine storm'.

Published in:

International Journal of Molecular Medicine, 2023, v. 52, n. 3, p. N.PAG, doi. 10.3892/ijmm.2023.5279

By:

Gasparello, Jessica;
Marzaro, Giovanni;
Papi, Chiara;
Gentili, Valentina;
Rizzo, Roberta;
Zurlo, Matteo;
Scapoli, Chiara;
Finotti, Alessia;
Gambari, Roberto

Publication type:

Article

Changes in hemoglobin profile reflect autologous blood transfusion misuse in sports.

Published in:

2018

By:

Lamberti, Nicola;
Finotti, Alessia;
Gasparello, Jessica;
Lampronti, Ilaria;
Zambon, Christel;
Cosenza, Lucia Carmela;
Fabbri, Enrica;
Bianchi, Nicoletta;
Dalla Corte, Francesca;
Govoni, Maurizio;
Reverberi, Roberto;
Gambari, Roberto;
Manfredini, Fabio

Publication type:

journal article

Synergistic effects of the combined treatment of U251 and T98G glioma cells with an anti-tubulin tetrahydrothieno[2,3-c]pyridine derivative and a peptide nucleic acid targeting miR-221-3p.

Published in:

International Journal of Oncology, 2021, v. 59, n. 2, p. N.PAG, doi. 10.3892/ijo.2021.5241

By:

Zurlo, Matteo;
Romagnoli, Romeo;
Oliva, Paola;
Gasparello, Jessica;
Finotti, Alessia;
Gambari, Roberto

Publication type:

Article

Targeting miR-155-5p and miR-221-3p by peptide nucleic acids induces caspase-3 activation and apoptosis in temozolomide-resistant T98G glioma cells.

Published in:

International Journal of Oncology, 2019, v. 55, n. 1, p. 59, doi. 10.3892/ijo.2019.4810

By:

Milani, Roberta;
Brognara, Eleonora;
Fabbri, Enrica;
Manicardi, Alex;
Corradini, Roberto;
Finotti, Alessia;
Gasparello, Jessica;
Borgatti, Monica;
Cosenza, Lucia Carmela;
Lampronti, Ilaria;
Dechecchi, Maria Cristina;
Cabrini, Giulio;
Gambari, Roberto

Publication type:

Article

Liquid biopsy and PCR-free ultrasensitive detection systems in oncology (Review).

Published in:

International Journal of Oncology, 2018, v. 53, n. 4, p. 1395, doi. 10.3892/ijo.2018.4516

By:

Finotti, Alessia;
Allegretti, Matteo;
Gasparello, Jessica;
Giacomini, Patrizio;
Spandidos, Demetrios A.;
Spoto, Giuseppe;
Gambari, Roberto

Publication type:

Article

High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222.

Published in:

International Journal of Oncology, 2016, v. 48, n. 3, p. 1029, doi. 10.3892/ijo.2015.3308

By:

BROGNARA, ELEONORA;
FABBRI, ENRICA;
MONTAGNER, GIULIA;
GASPARELLO, JESSICA;
MANICARDI, ALEX;
CORRADINI, ROBERTO;
BIANCHI, NICOLETTA;
FINOTTI, ALESSIA;
BREVEGLIERI, GIULIA;
BORGATTI, MONICA;
LAMPRONTI, ILARIA;
MILANI, ROBERTA;
CRISTINA DECHECCHI, MARIA;
CABRINI, GIULIO;
GAMBARI, ROBERTO

Publication type:

Article

A Peptide-Nucleic Acid Targeting miR-335-5p Enhances Expression of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene with the Possible Involvement of the CFTR Scaffolding Protein NHERF1.

Published in:

Biomedicines, 2021, v. 9, n. 2, p. 117, doi. 10.3390/biomedicines9020117

By:

Tamanini, Anna;
Fabbri, Enrica;
Jakova, Tiziana;
Gasparello, Jessica;
Manicardi, Alex;
Corradini, Roberto;
Finotti, Alessia;
Borgatti, Monica;
Lampronti, Ilaria;
Munari, Silvia;
Dechecchi, Maria Cristina;
Cabrini, Giulio;
Gambari, Roberto;
Blasi, Francesco B.

Publication type:

Article

Enzymatic Spermine Metabolites Induce Apoptosis Associated with Increase of p53, caspase-3 and miR-34a in Both Neuroblastoma Cells, SJNKP and the N-Myc-Amplified Form IMR5.

Published in:

Cells (2073-4409), 2021, v. 10, n. 8, p. 1950, doi. 10.3390/cells10081950

By:

Kanamori, Yuta;
Finotti, Alessia;
Magno, Laura Di;
Canettieri, Gianluca;
Tahara, Tomoaki;
Timeus, Fabio;
Greco, Antonio;
Tirassa, Paola;
Gasparello, Jessica;
Fino, Pasquale;
Di Liegro, Carlo Maria;
Proia, Patrizia;
Schiera, Gabriella;
Di Liegro, Italia;
Gambari, Roberto;
Agostinelli, Enzo

Publication type:

Article

Efficient cell penetration and delivery of peptide nucleic acids by an argininocalix[4]arene.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-39211-4

By:

Gasparello, Jessica;
Manicardi, Alex;
Casnati, Alessandro;
Corradini, Roberto;
Gambari, Roberto;
Finotti, Alessia;
Sansone, Francesco

Publication type:

Article

Demonstrating specificity of bioactive peptide nucleic acids (PNAs) targeting microRNAs for practical laboratory classes of applied biochemistry and pharmacology.

Published in:

PLoS ONE, 2019, v. 14, n. 9, p. 1, doi. 10.1371/journal.pone.0221923

By:

Gasparello, Jessica;
Papi, Chiara;
Zurlo, Matteo;
Corradini, Roberto;
Gambari, Roberto;
Finotti, Alessia

Publication type:

Article

MicroRNAs and Long Non-coding RNAs in Genetic Diseases.

Published in:

Molecular Diagnosis & Therapy, 2019, v. 23, n. 2, p. 155, doi. 10.1007/s40291-018-0380-6

By:

Finotti, Alessia;
Fabbri, Enrica;
Lampronti, Ilaria;
Gasparello, Jessica;
Borgatti, Monica;
Gambari, Roberto

Publication type:

Article

Altered erythroid-related miRNA levels as a possible novel biomarker for detection of autologous blood transfusion misuse in sport.

Published in:

2019

By:

Gasparello, Jessica;
Lamberti, Nicola;
Papi, Chiara;
Lampronti, Ilaria;
Cosenza, Lucia Carmela;
Fabbri, Enrica;
Bianchi, Nicoletta;
Zambon, Christel;
Dalla Corte, Francesca;
Govoni, Maurizio;
Reverberi, Roberto;
Manfredini, Fabio;
Gambari, Roberto;
Finotti, Alessia

Publication type:

journal article

The Cystic Fibrosis Transmembrane Conductance Regulator Gene (CFTR) Is under Post-Transcriptional Control of microRNAs: Analysis of the Effects of agomiRNAs Mimicking miR-145-5p, miR-101-3p, and miR-335-5p.

Published in:

Non-Coding RNA, 2023, v. 9, n. 2, p. 29, doi. 10.3390/ncrna9020029

By:

Papi, Chiara;
Gasparello, Jessica;
Zurlo, Matteo;
Cosenza, Lucia Carmela;
Gambari, Roberto;
Finotti, Alessia

Publication type:

Article

Targeting DNA Binding for NF-κB as an Anticancer Approach in Hepatocellular Carcinoma.

Published in:

Cells (2073-4409), 2018, v. 7, n. 10, p. 177, doi. 10.3390/cells7100177

By:

Chung, Po Yee;
Lam, Pik Ling;
Zhou, Yuanyuan;
Gasparello, Jessica;
Finotti, Alessia;
Chilin, Adriana;
Marzaro, Giovanni;
Gambari, Roberto;
Bian, Zhaoxiang;
Kwok, Wai Ming;
Wong, Wai Yeung;
Wang, Xi;
Lam, Alfred King-Yin;
Chan, Albert Sun-Chi;
Li, Xingshu;
Ma, Jessica Yuen Wuen;
Chui, Chung Hin;
Lam, Kim Hung;
Tang, Johnny Cheuk On

Publication type:

Article

Cationic Calix[4]arene Vectors to Efficiently Deliver AntimiRNA Peptide Nucleic Acids (PNAs) and miRNA Mimics.

Published in:

Pharmaceutics, 2023, v. 15, n. 8, p. 2121, doi. 10.3390/pharmaceutics15082121

By:

Gasparello, Jessica;
Papi, Chiara;
Zurlo, Matteo;
Volpi, Stefano;
Gambari, Roberto;
Corradini, Roberto;
Casnati, Alessandro;
Sansone, Francesco;
Finotti, Alessia

Publication type:

Article

Combined Treatment of Cancer Cells Using Allyl Palladium Complexes Bearing Purine-Based NHC Ligands and Molecules Targeting MicroRNAs miR-221-3p and miR-222-3p: Synergistic Effects on Apoptosis.

Published in:

Pharmaceutics, 2023, v. 15, n. 5, p. 1332, doi. 10.3390/pharmaceutics15051332

By:

Tupini, Chiara;
Zurlo, Matteo;
Gasparello, Jessica;
Lodi, Irene;
Finotti, Alessia;
Scattolin, Thomas;
Visentin, Fabiano;
Gambari, Roberto;
Lampronti, Ilaria

Publication type:

Article

Effects of Sirolimus treatment on patients with β‐Thalassemia: Lymphocyte immunophenotype and biological activity of memory CD4<sup>+</sup> and CD8<sup>+</sup> T cells.

Published in:

Journal of Cellular & Molecular Medicine, 2023, v. 27, n. 3, p. 353, doi. 10.1111/jcmm.17655

By:

Zurlo, Matteo;
Nicoli, Francesco;
Proietto, Davide;
Dallan, Beatrice;
Zuccato, Cristina;
Cosenza, Lucia Carmela;
Gasparello, Jessica;
Papi, Chiara;
d'Aversa, Elisabetta;
Borgatti, Monica;
Scapoli, Chiara;
Finotti, Alessia;
Gambari, Roberto

Publication type:

Article

The Long Scientific Journey of Sirolimus (Rapamycin): From the Soil of Easter Island (Rapa Nui) to Applied Research and Clinical Trials on β-Thalassemia and Other Hemoglobinopathies.

Published in:

Biology (2079-7737), 2023, v. 12, n. 9, p. 1202, doi. 10.3390/biology12091202

By:

Gambari, Roberto;
Zuccato, Cristina;
Cosenza, Lucia Carmela;
Zurlo, Matteo;
Gasparello, Jessica;
Finotti, Alessia;
Gamberini, Maria Rita;
Prosdocimi, Marco

Publication type:

Article

Effects of Mithramycin on BCL11A Gene Expression and on the Interaction of the BCL11A Transcriptional Complex to γ-Globin Gene Promoter Sequences.

Published in:

Genes, 2023, v. 14, n. 10, p. 1927, doi. 10.3390/genes14101927

By:

Finotti, Alessia;
Gasparello, Jessica;
Zuccato, Cristina;
Cosenza, Lucia Carmela;
Fabbri, Enrica;
Bianchi, Nicoletta;
Gambari, Roberto

Publication type:

Article

Production and Characterization of K562 Cellular Clones Hyper-Expressing the Gene Encoding α-Globin: Preliminary Analysis of Biomarkers Associated with Autophagy.

Published in:

Genes, 2023, v. 14, n. 3, p. 556, doi. 10.3390/genes14030556

By:

Zurlo, Matteo;
Gasparello, Jessica;
Cosenza, Lucia Carmela;
Breveglieri, Giulia;
Papi, Chiara;
Zuccato, Cristina;
Gambari, Roberto;
Finotti, Alessia

Publication type:

Article

Enhancing the Expression of CFTR Using Antisense Molecules against MicroRNA miR-145-5p.

Published in:

2019

By:

Finotti, Alessia;
Gasparello, Jessica;
Fabbri, Enrica;
Tamanini, Anna;
Corradini, Roberto;
Dechecchi, Maria Cristina;
Cabrini, Giulio;
Gambari, Roberto

Publication type:

Letter

Surface plasmon resonance based analysis of the binding of LYAR protein to the rs368698783 (G>A) polymorphic Aγ-globin gene sequences mutated in β-thalassemia.

Published in:

Analytical & Bioanalytical Chemistry, 2019, v. 411, n. 29, p. 7699, doi. 10.1007/s00216-019-01987-9

By:

Gemmo, Chiara;
Breveglieri, Giulia;
Marzaro, Giovanni;
Lampronti, Ilaria;
Cosenza, Lucia Carmela;
Gasparello, Jessica;
Zuccato, Cristina;
Fabbri, Enrica;
Borgatti, Monica;
Chilin, Adriana;
Finotti, Alessia;
Gambari, Roberto

Publication type:

Article

Aged Garlic Extract (AGE) and Its Constituent S-Allyl-Cysteine (SAC) Inhibit the Expression of Pro-Inflammatory Genes Induced in Bronchial Epithelial IB3-1 Cells by Exposure to the SARS-CoV-2 Spike Protein and the BNT162b2 Vaccine.

Published in:

Molecules, 2024, v. 29, n. 24, p. 5938, doi. 10.3390/molecules29245938

By:

Gasparello, Jessica;
Papi, Chiara;
Marzaro, Giovanni;
Macone, Alberto;
Zurlo, Matteo;
Finotti, Alessia;
Agostinelli, Enzo;
Gambari, Roberto

Publication type:

Article

Treatment of Human Glioblastoma U251 Cells with Sulforaphane and a Peptide Nucleic Acid (PNA) Targeting miR-15b-5p: Synergistic Effects on Induction of Apoptosis.

Published in:

Molecules, 2022, v. 27, n. 4, p. 1299, doi. 10.3390/molecules27041299

By:

Gasparello, Jessica;
Papi, Chiara;
Zurlo, Matteo;
Gambari, Laura;
Rozzi, Andrea;
Manicardi, Alex;
Corradini, Roberto;
Gambari, Roberto;
Finotti, Alessia

Publication type:

Article

A Peptide Nucleic Acid (PNA) Masking the miR-145-5p Binding Site of the 3′UTR of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) mRNA Enhances CFTR Expression in Calu-3 Cells.

Published in:

Molecules, 2020, v. 25, n. 7, p. 1677, doi. 10.3390/molecules25071677

By:

Sultan, Shaiq;
Rozzi, Andrea;
Gasparello, Jessica;
Manicardi, Alex;
Corradini, Roberto;
Papi, Chiara;
Finotti, Alessia;
Lampronti, Ilaria;
Reali, Eva;
Cabrini, Giulio;
Gambari, Roberto;
Borgatti, Monica;
Yavin, Eylon

Publication type:

Article

A Peptide Nucleic Acid against MicroRNA miR-145-5p Enhances the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells.

Published in:

Molecules, 2018, v. 23, n. 1, p. 71, doi. 10.3390/molecules23010071

By:

Fabbri, Enrica;
Tamanini, Anna;
Jakova, Tiziana;
Gasparello, Jessica;
Manicardi, Alex;
Corradini, Roberto;
Sabbioni, Giuseppe;
Finotti, Alessia;
Borgatti, Monica;
Lampronti, Ilaria;
Munari, Silvia;
Dechecchi, Maria Cristina;
Cabrini, Giulio;
Gambari, Roberto

Publication type:

Article

Teaching during COVID-19 pandemic in practical laboratory classes of applied biochemistry and pharmacology: A validated fast and simple protocol for detection of SARS-CoV-2 Spike sequences.

Published in:

PLoS ONE, 2022, v. 17, n. 4, p. 1, doi. 10.1371/journal.pone.0266419

By:

Gasparello, Jessica;
Papi, Chiara;
Zurlo, Matteo;
Cosenza, Lucia Carmela;
Breveglieri, Giulia;
Zuccato, Cristina;
Gambari, Roberto;
Finotti, Alessia

Publication type:

Article

BCL11A mRNA Targeting by miR-210: A Possible Network Regulating γ-Globin Gene Expression.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 12, p. 2530, doi. 10.3390/ijms18122530

By:

Gasparello, Jessica;
Fabbri, Enrica;
Bianchi, Nicoletta;
Breveglieri, Giulia;
Zuccato, Cristina;
Borgatti, Monica;
Gambari, Roberto;
Finotti, Alessia

Publication type:

Article

Preliminary results and a theoretical perspective of co‑treatment using a miR‑93‑5p mimic and aged garlic extract to inhibit the expression of the pro‑inflammatory interleukin‑8 gene.

Published in:

Experimental & Therapeutic Medicine, 2025, v. 29, n. 4, p. N.PAG, doi. 10.3892/etm.2025.12835

By:

Gambari, Roberto;
Papi, Chiara;
Gasparello, Jessica;
Agostinelli, Enzo;
Finotti, Alessia

Publication type:

Article

Decrease in α-Globin and Increase in the Autophagy-Activating Kinase ULK1 mRNA in Erythroid Precursors from β-Thalassemia Patients Treated with Sirolimus.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 20, p. 15049, doi. 10.3390/ijms242015049

By:

Zurlo, Matteo;
Zuccato, Cristina;
Cosenza, Lucia Carmela;
Gasparello, Jessica;
Gamberini, Maria Rita;
Stievano, Alice;
Fortini, Monica;
Prosdocimi, Marco;
Finotti, Alessia;
Gambari, Roberto

Publication type:

Article

The rs368698783 (G>A) Polymorphism Affecting LYAR Binding to the Aγ-Globin Gene Is Associated with High Fetal Hemoglobin (HbF) in β-Thalassemia Erythroid Precursor Cells Treated with HbF Inducers.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 776, doi. 10.3390/ijms24010776

By:

Zuccato, Cristina;
Cosenza, Lucia Carmela;
Zurlo, Matteo;
Breveglieri, Giulia;
Bianchi, Nicoletta;
Lampronti, Ilaria;
Gasparello, Jessica;
Scapoli, Chiara;
Borgatti, Monica;
Finotti, Alessia;
Gambari, Roberto

Publication type:

Article

Combined Treatment of Bronchial Epithelial Calu-3 Cells with Peptide Nucleic Acids Targeting miR-145-5p and miR-101-3p: Synergistic Enhancement of the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 16, p. 9348, doi. 10.3390/ijms23169348

By:

Papi, Chiara;
Gasparello, Jessica;
Zurlo, Matteo;
Manicardi, Alex;
Corradini, Roberto;
Cabrini, Giulio;
Gambari, Roberto;
Finotti, Alessia

Publication type:

Article

Synergistic Effects of A Combined Treatment of Glioblastoma U251 Cells with An Anti-miR-10b-5p Molecule and An AntiCancer Agent Based on 1-(3′,4′,5′-Trimethoxyphenyl)-2-Aryl-1 H -Imidazole Scaffold.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 11, p. 5991, doi. 10.3390/ijms23115991

By:

Zurlo, Matteo;
Romagnoli, Romeo;
Oliva, Paola;
Gasparello, Jessica;
Finotti, Alessia;
Gambari, Roberto

Publication type:

Article