Works by Garg, Nisha Jain

Results: 36

Gene Expression Profiling and Functional Characterization of Macrophages in Response to Circulatory Microparticles Produced during Trypanosoma cruzi Infection and Chagas Disease.

Published in:

Journal of Innate Immunity, 2017, v. 9, n. 2, p. 203, doi. 10.1159/000451055

By:

Chowdhury, Imran H.;
Koo, Sue-jie;
Gupta, Shivali;
Liang, Lisa Yi;
Bahar, Bojlul;
Silla, Laura;
Nuñez-Burgos, Julio;
Barrientos, Natalia;
Zago, Maria Paola;
Garg, Nisha Jain

Publication type:

Article

Origin of Monocytes/Macrophages Contributing to Chronic Inflammation in Chagas Disease: SIRT1 Inhibition of FAK-NFkB-Dependent Proliferation and Proinflammatory Activation of Macrophages.

Published in:

Cells (2073-4409), 2020, v. 9, n. 1, p. 1, doi. 10.3390/cells9010080

By:

Xianxiu Wan;
Chowdhury, Imran Hussain;
Zuliang Jie;
Choudhuri, Subhadip;
Garg, Nisha Jain

Publication type:

Article

Sirtuin Control of Mitochondrial Dysfunction, Oxidative Stress, and Inflammation in Chagas Disease Models.

Published in:

Frontiers in Cellular & Infection Microbiology, 2021, v. 11, p. 1, doi. 10.3389/fcimb.2021.693051

By:

Wan, Xianxiu;
Garg, Nisha Jain

Publication type:

Article

Hepatotoxicity in Mice of a Novel Anti-parasite Drug Candidate Hydroxymethylnitrofurazone: A Comparison with Benznidazole.

Published in:

PLoS Neglected Tropical Diseases, 2014, v. 8, n. 10, p. 1, doi. 10.1371/journal.pntd.0003231

By:

Davies, Carolina;
Dey, Nilay;
Negrette, Olga Sanchez;
Parada, Luis Antonio;
Basombrio, Miguel A.;
Garg, Nisha Jain

Publication type:

Article

Hepatotoxicity in Mice of a Novel Anti-parasite Drug Candidate Hydroxymethylnitrofurazone: A Comparison with Benznidazole.

Published in:

PLoS Neglected Tropical Diseases, 2014, v. 8, n. 10, p. 1, doi. 10.1371/journal.pntd.0003231

By:

Davies, Carolina;
Dey, Nilay;
Negrette, Olga Sanchez;
Parada, Luis Antonio;
Basombrio, Miguel A.;
Garg, Nisha Jain

Publication type:

Article

Innate Immune Responses and Antioxidant/Oxidant Imbalance Are Major Determinants of Human Chagas Disease.

Published in:

PLoS Neglected Tropical Diseases, 2013, v. 7, n. 8, p. 1, doi. 10.1371/journal.pntd.0002364

By:

Dhiman, Monisha;
Coronado, Yun A.;
Vallejo, Cecilia K.;
Petersen, John R.;
Ejilemele, Adetoun;
Nuñez, Sonia;
Zago, Maria Paola;
Spratt, Heidi;
Garg, Nisha Jain

Publication type:

Article

Innate Immune Responses and Antioxidant/Oxidant Imbalance Are Major Determinants of Human Chagas Disease.

Published in:

PLoS Neglected Tropical Diseases, 2013, v. 7, n. 8, p. 1, doi. 10.1371/journal.pntd.0002364

By:

Dhiman, Monisha;
Coronado, Yun A.;
Vallejo, Cecilia K.;
Petersen, John R.;
Ejilemele, Adetoun;
Nuñez, Sonia;
Zago, Maria Paola;
Spratt, Heidi;
Garg, Nisha Jain

Publication type:

Article

Antigenicity and Diagnostic Potential of Vaccine Candidates in Human Chagas Disease.

Published in:

PLoS Neglected Tropical Diseases, 2013, v. 7, n. 1, p. 1, doi. 10.1371/journal.pntd.0002018

By:

Gupta, Shivali;
Wan, Xianxiu;
Zago, Maria P.;
Martinez Sellers, Valena C.;
Silva, Trevor S.;
Assiah, Dadjah;
Dhiman, Monisha;
Nuñez, Sonia;
Petersen, John R.;
Vázquez-Chagoyán, Juan C.;
Estrada-Franco, Jose G.;
Garg, Nisha Jain

Publication type:

Article

Antigen-Based Nano-Immunotherapy Controls Parasite Persistence, Inflammatory and Oxidative Stress, and Cardiac Fibrosis, the Hallmarks of Chronic Chagas Cardiomyopathy, in A Mouse Model of Trypanosoma cruzi Infection.

Published in:

Vaccines, 2020, v. 8, n. 1, p. 96, doi. 10.3390/vaccines8010096

By:

Lokugamage, Nandadeva;
Choudhuri, Subhadip;
Davies, Carolina;
Chowdhury, Imran Hussain;
Garg, Nisha Jain

Publication type:

Article

Pentose Phosphate shunt Modulates reactive Oxygen species and nitric Oxide Production controlling Trypanosoma cruzi in Macrophages.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00202

By:

Koo, Sue-jie;
Szczesny, Bartosz;
Wan, Xianxiu;
Putluri, Nagireddy;
Garg, Nisha Jain

Publication type:

Article

S-Nitrosylation Proteome Profile of Peripheral Blood Mononuclear Cells in Human Heart Failure.

Published in:

International Journal of Proteomics, 2016, p. 1, doi. 10.1155/2016/1384523

By:

Koo, Sue-jie;
Spratt, Heidi M.;
Soman, Kizhake V.;
Stafford, Susan;
Gupta, Shivali;
Petersen, John R.;
Zago, Maria P.;
Kuyumcu-Martinez, Muge N.;
Brasier, Allan R.;
Wiktorowicz, John E.;
Garg, Nisha Jain

Publication type:

Article

PARP1 depletion improves mitochondrial and heart function in Chagas disease: Effects on POLG dependent mtDNA maintenance.

Published in:

PLoS Pathogens, 2018, v. 14, n. 6, p. 1, doi. 10.1371/journal.ppat.1007065

By:

Wen, Jake Jianjun;
Yin, Yuhui Whitney;
Garg, Nisha Jain

Publication type:

Article

Use of a small molecule integrin activator as a systemically administered vaccine adjuvant in controlling Chagas disease.

Published in:

NPJ Vaccines, 2021, v. 6, n. 1, p. 1, doi. 10.1038/s41541-021-00378-5

By:

Lokugamage, Nandadeva;
Chowdhury, Imran H.;
Biediger, Ronald J.;
Market, Robert V.;
Khounlo, Sayadeth;
Warier, Navin D.;
Hwang, Shen-An;
Actor, Jeffrey K.;
Woodside, Darren G.;
Marathi, Upendra;
Vanderslice, Peter;
Garg, Nisha Jain

Publication type:

Article

Oxidative stress implications for therapeutic vaccine development against Chagas disease.

Published in:

2021

By:

Choudhuri, Subhadip;
Rios, Lizette;
Vázquez-Chagoyán, Juan Carlos;
Garg, Nisha Jain

Publication type:

Literature Review

Testing the Efficacy of a Multi-Component DNA-Prime/DNA-Boost Vaccine against Trypanosoma cruzi Infection in Dogs.

Published in:

PLoS Neglected Tropical Diseases, 2011, v. 5, n. 5, p. 1, doi. 10.1371/journal.pntd.0001050

By:

Aparicio-Burgos, José E.;
Ochoa-García, Laucel;
Zepeda-Escobar, José Antonio;
Gupta, Shivali;
Dhiman, Monisha;
Martínez, José Simón;
de Oca-Jiménez, Roberto Montes;
Arreola, Margarita Val;
Barbabosa-Pliego, Alberto;
Vázquez-Chagoyán, Juan C.;
Garg, Nisha Jain

Publication type:

Article

Testing the Efficacy of a Multi-Component DNA-Prime/ DNA-Boost Vaccine against Trypanosoma cruzi Infection in Dogs.

Published in:

PLoS Neglected Tropical Diseases, 2011, v. 5, n. 5, p. 1, doi. 10.1371/journal.pntd.0001050

By:

Aparicio-Burgos, JoséE.;
Ochoa-García, Laucel;
Zepeda-Escobar, JoséAntonio;
Gupta, Shivali;
Dhiman, Monisha;
Martínez1, Jos éSimón;
Oca-Jiménez, Roberto Montes de;
Arreola, Margarita Val;
Barbabosa-Pliego, Alberto;
Vázquez-Chagoyán, Juan C.;
Garg, Nisha Jain

Publication type:

Article

Prophylactic Efficacy of TcVac2 against Trypanosoma cruzi in Mice.

Published in:

PLoS Neglected Tropical Diseases, 2010, v. 4, n. 8, p. 1, doi. 10.1371/journal.pntd.0000797

By:

Gupta, Shivali;
Garg, Nisha Jain

Publication type:

Article

Prophylactic Efficacy of TcVac2 against Trypanosoma cruzi in Mice.

Published in:

PLoS Neglected Tropical Diseases, 2010, v. 4, n. 8, p. 1, doi. 10.1371/journal.pntd.0000797

By:

Gupta, Shivali;
Garg, Nisha Jain

Publication type:

Article

P47phox−/− Mice Are Compromised in Expansion and Activation of CD8+ T Cells and Susceptible to Trypanosoma cruzi Infection.

Published in:

PLoS Pathogens, 2014, v. 10, n. 12, p. 1, doi. 10.1371/journal.ppat.1004516

By:

Dhiman, Monisha;
Garg, Nisha Jain

Publication type:

Article

Subunit nanovaccine elicited T cell functional activation controls Trypanosoma cruzi mediated maternal and placental tissue damage and improves pregnancy outcomes in mice.

Published in:

NPJ Vaccines, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41541-023-00782-z

By:

Rios, Lizette Elaine;
Lokugamage, Nandadeva;
Choudhuri, Subhadip;
Chowdhury, Imran Hussain;
Garg, Nisha Jain

Publication type:

Article

Developments in the management of Chagas cardiomyopathy.

Published in:

2015

By:

Tanowitz, Herbert B;
Machado, Fabiana S;
Spray, David C;
Friedman, Joel M;
Weiss, Oren S;
Lora, Jose N;
Nagajyothi, Jyothi;
Moraes, Diego N;
Garg, Nisha Jain;
Nunes, Maria Carmo P;
Ribeiro, Antonio Luiz P

Publication type:

journal article

Hepatocyte Nuclear Factor 4 Alpha: A Key Regulator of Liver Disease Pathology and Haemostatic Disorders.

Published in:

Liver International, 2025, v. 45, n. 6, p. 1, doi. 10.1111/liv.16245

By:

Choudhuri, Subhadip;
Garg, Nisha Jain

Publication type:

Article

Mitochondrial Regulation of Macrophage Response Against Pathogens.

Published in:

Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.622602

By:

Choudhuri, Subhadip;
Chowdhury, Imran Hussain;
Garg, Nisha Jain

Publication type:

Article

Experimental Nanovaccine Offers Protection Against Repeat Exposures to Trypanosoma cruzi Through Activation of Polyfunctional T Cell Response.

Published in:

Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.595039

By:

Chowdhury, Imran H.;
Lokugamage, Nandadeva;
Garg, Nisha Jain

Publication type:

Article

Oxidative Stress in Chagas Disease.

Published in:

Interdisciplinary Perspectives on Infectious Diseases, 2009, p. 1, doi. 10.1155/2009/190354

By:

Gupta, Shivali;
Jian-Jun Wen;
Garg, Nisha Jain

Publication type:

Article

Potential Utility of Protein Targets of Cysteine-S-Nitrosylation in Identifying Clinical Disease Status in Human Chagas Disease.

Published in:

Frontiers in Microbiology, 2019, p. N.PAG, doi. 10.3389/fmicb.2018.03320

By:

Zago, Maria Paola;
Wiktorowicz, John E.;
Spratt, Heidi;
Koo, Sue-Jie;
Barrientos, Natalia;
Nuñez Burgos, Aida;
Nuñez Burgos, Julio;
Iñiguez, Facundo;
Botelli, Valentina;
Leon de la Fuente, Ricardo;
Garg, Nisha Jain

Publication type:

Article

Manganese superoxide dismutase deficiency exacerbates the mitochondrial ROS production and oxidative damage in Chagas disease.

Published in:

PLoS Neglected Tropical Diseases, 2018, v. 12, n. 7, p. 1, doi. 10.1371/journal.pntd.0006687

By:

Wen, Jake J.;
Garg, Nisha Jain

Publication type:

Article

Therapeutic Efficacy of a Subunit Vaccine in Controlling Chronic Trypanosoma cruzi Infection and Chagas Disease Is Enhanced by Glutathione Peroxidase Over-Expression.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0130562

By:

Gupta, Shivali;
Smith, Charity;
Auclair, Sarah;
Delgadillo, Anahi De Jesus;
Garg, Nisha Jain

Publication type:

Article

Caspase-1/ASC Inflammasome-Mediated Activation of IL-1β–ROS–NF-κB Pathway for Control of Trypanosoma cruzi Replication and Survival Is Dispensable in NLRP3−/− Macrophages.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0111539

By:

Dey, Nilay;
Sinha, Mala;
Gupta, Shivali;
Gonzalez, Mariela Natacha;
Fang, Rong;
Endsley, Janice J.;
Luxon, Bruce A.;
Garg, Nisha Jain

Publication type:

Article

TcVac3 Induced Control of Trypanosoma cruzi Infection and Chronic Myocarditis in Mice.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059434

By:

Gupta, Shivali;
Garg, Nisha Jain

Publication type:

Article

Cardiac-Oxidized Antigens Are Targets of Immune Recognition by Antibodies and Potential Molecular Determinants in Chagas Disease Pathogenesis.

Published in:

PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0028449

By:

Dhiman, Monisha;
Zago, Maria Paola;
Nunez, Sonia;
Amoroso, Alejandro;
Rementeria, Hugo;
Dousset, Pierre;
Burgos, Federico Nunez;
Garg, Nisha Jain

Publication type:

Article

TcG2/TcG4 DNA Vaccine Induces Th1 Immunity Against Acute Trypanosoma cruzi Infection: Adjuvant and Antigenic Effects of Heterologous T. rangeli Booster Immunization.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01456

By:

Gupta, Shivali;
Salgado-Jiménez, Berenice;
Lokugamage, Nandadeva;
Vázquez-Chagoyán, Juan Carlos;
Garg, Nisha Jain

Publication type:

Article

PARP1-cGAS-NF-κB pathway of proinflammatory macrophage activation by extracellular vesicles released during Trypanosoma cruzi infection and Chagas disease.

Published in:

PLoS Pathogens, 2020, v. 16, n. 4, p. 1, doi. 10.1371/journal.ppat.1008474

By:

Choudhuri, Subhadip;
Garg, Nisha Jain

Publication type:

Article

Changes in Proteome Profile of Peripheral Blood Mononuclear Cells in Chronic Chagas Disease.

Published in:

PLoS Neglected Tropical Diseases, 2016, v. 10, n. 2, p. 1, doi. 10.1371/journal.pntd.0004490

By:

Garg, Nisha Jain;
Soman, Kizhake V.;
Zago, Maria P.;
Koo, Sue-Jie;
Spratt, Heidi;
Stafford, Susan;
Blell, Zinzi N.;
Gupta, Shivali;
Nuñez Burgos, Julio;
Barrientos, Natalia;
Brasier, Allan R.;
Wiktorowicz, John E.

Publication type:

Article

NADPH oxidase inhibition ameliorates Trypanosoma cruzi-induced myocarditis during Chagas disease.

Published in:

Journal of Pathology, 2011, v. 225, n. 4, p. 583, doi. 10.1002/path.2975

By:

Dhiman, Monisha;
Garg, Nisha Jain

Publication type:

Article

SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Disease.

Published in:

PLoS Pathogens, 2016, v. 12, n. 10, p. 1, doi. 10.1371/journal.ppat.1005954

By:

Wan, Xianxiu;
Wen, Jian-jun;
Koo, Sue-Jie;
Liang, Lisa Yi;
Garg, Nisha Jain

Publication type:

Article

Works by Garg, Nisha Jain

Gene Expression Profiling and Functional Characterization of Macrophages in Response to Circulatory Microparticles Produced during Trypanosoma cruzi Infection and Chagas Disease.

Origin of Monocytes/Macrophages Contributing to Chronic Inflammation in Chagas Disease: SIRT1 Inhibition of FAK-NFkB-Dependent Proliferation and Proinflammatory Activation of Macrophages.

Sirtuin Control of Mitochondrial Dysfunction, Oxidative Stress, and Inflammation in Chagas Disease Models.

Hepatotoxicity in Mice of a Novel Anti-parasite Drug Candidate Hydroxymethylnitrofurazone: A Comparison with Benznidazole.

Hepatotoxicity in Mice of a Novel Anti-parasite Drug Candidate Hydroxymethylnitrofurazone: A Comparison with Benznidazole.

Innate Immune Responses and Antioxidant/Oxidant Imbalance Are Major Determinants of Human Chagas Disease.

Innate Immune Responses and Antioxidant/Oxidant Imbalance Are Major Determinants of Human Chagas Disease.

Antigenicity and Diagnostic Potential of Vaccine Candidates in Human Chagas Disease.

Antigen-Based Nano-Immunotherapy Controls Parasite Persistence, Inflammatory and Oxidative Stress, and Cardiac Fibrosis, the Hallmarks of Chronic Chagas Cardiomyopathy, in A Mouse Model of Trypanosoma cruzi Infection.

Pentose Phosphate shunt Modulates reactive Oxygen species and nitric Oxide Production controlling Trypanosoma cruzi in Macrophages.

S-Nitrosylation Proteome Profile of Peripheral Blood Mononuclear Cells in Human Heart Failure.

PARP1 depletion improves mitochondrial and heart function in Chagas disease: Effects on POLG dependent mtDNA maintenance.

Use of a small molecule integrin activator as a systemically administered vaccine adjuvant in controlling Chagas disease.

Oxidative stress implications for therapeutic vaccine development against Chagas disease.

Testing the Efficacy of a Multi-Component DNA-Prime/DNA-Boost Vaccine against Trypanosoma cruzi Infection in Dogs.

Testing the Efficacy of a Multi-Component DNA-Prime/ DNA-Boost Vaccine against Trypanosoma cruzi Infection in Dogs.

Prophylactic Efficacy of TcVac2 against Trypanosoma cruzi in Mice.

Prophylactic Efficacy of TcVac2 against Trypanosoma cruzi in Mice.

P47<sup>phox−/−</sup> Mice Are Compromised in Expansion and Activation of CD8<sup>+</sup> T Cells and Susceptible to Trypanosoma cruzi Infection.

Subunit nanovaccine elicited T cell functional activation controls Trypanosoma cruzi mediated maternal and placental tissue damage and improves pregnancy outcomes in mice.

Developments in the management of Chagas cardiomyopathy.

Hepatocyte Nuclear Factor 4 Alpha: A Key Regulator of Liver Disease Pathology and Haemostatic Disorders.

Mitochondrial Regulation of Macrophage Response Against Pathogens.

Experimental Nanovaccine Offers Protection Against Repeat Exposures to Trypanosoma cruzi Through Activation of Polyfunctional T Cell Response.

Oxidative Stress in Chagas Disease.

Potential Utility of Protein Targets of Cysteine-S-Nitrosylation in Identifying Clinical Disease Status in Human Chagas Disease.

Manganese superoxide dismutase deficiency exacerbates the mitochondrial ROS production and oxidative damage in Chagas disease.

Therapeutic Efficacy of a Subunit Vaccine in Controlling Chronic Trypanosoma cruzi Infection and Chagas Disease Is Enhanced by Glutathione Peroxidase Over-Expression.

Caspase-1/ASC Inflammasome-Mediated Activation of IL-1β–ROS–NF-κB Pathway for Control of Trypanosoma cruzi Replication and Survival Is Dispensable in NLRP3<sup>−/−</sup> Macrophages.

TcVac3 Induced Control of <i>Trypanosoma cruzi</i> Infection and Chronic Myocarditis in Mice.

Cardiac-Oxidized Antigens Are Targets of Immune Recognition by Antibodies and Potential Molecular Determinants in Chagas Disease Pathogenesis.

TcG2/TcG4 DNA Vaccine Induces Th1 Immunity Against Acute Trypanosoma cruzi Infection: Adjuvant and Antigenic Effects of Heterologous T. rangeli Booster Immunization.

PARP1-cGAS-NF-κB pathway of proinflammatory macrophage activation by extracellular vesicles released during Trypanosoma cruzi infection and Chagas disease.

Changes in Proteome Profile of Peripheral Blood Mononuclear Cells in Chronic Chagas Disease.

NADPH oxidase inhibition ameliorates Trypanosoma cruzi-induced myocarditis during Chagas disease.

SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Disease.