Found: 4

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  • Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling.

    Published in:
    2016
    By:
    • Le Bihan, Amélie;
    • de Kanter, Ruben;
    • Angulo-Barturen, Iñigo;
    • Binkert, Christoph;
    • Boss, Christoph;
    • Brun, Reto;
    • Brunner, Ralf;
    • Buchmann, Stephan;
    • Burrows, Jeremy;
    • Dechering, Koen J.;
    • Delves, Michael;
    • Ewerling, Sonja;
    • Ferrer, Santiago;
    • Fischli, Christoph;
    • Gamo–Benito, Francisco Javier;
    • Gnädig, Nina F.;
    • Heidmann, Bibia;
    • Jiménez-Díaz, María Belén;
    • Leroy, Didier;
    • Martínez, Maria Santos
    Publication type:
    journal article

  • A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria.

    Published in:
    Science Translational Medicine, 2015, v. 7, n. 296, p. 1, doi. 10.1126/scitranslmed.aaa6645
    By:
    • Phillips, Margaret A.;
    • Lotharius, Julie;
    • Marsh, Kennan;
    • White, John;
    • Dayan, Anthony;
    • White, Karen L.;
    • Njoroge, Jacqueline W.;
    • El Mazouni, Farah;
    • Yanbin Lao;
    • Kokkonda, Sreekanth;
    • Tomchick, Diana R.;
    • Xiaoyi Deng;
    • Laird, Trevor;
    • Bhatia, Sangeeta N.;
    • March, Sandra;
    • Ng, Caroline L.;
    • Fidock, David A.;
    • Wittlin, Sergio;
    • Lafuente-Monasterio, Maria;
    • Gamo Benito, Francisco Javier
    Publication type:
    Article

  • Fueling Open-Source Drug Discovery: 177 Small-Molecule Leads against Tuberculosis.

    Published in:
    ChemMedChem, 2013, v. 8, n. 2, p. 313, doi. 10.1002/cmdc.201200428
    By:
    • Ballell, Lluís;
    • Bates, Robert H.;
    • Young, Rob J.;
    • Alvarez‐Gomez, Daniel;
    • Alvarez‐Ruiz, Emilio;
    • Barroso, Vanessa;
    • Blanco, Delia;
    • Crespo, Benigno;
    • Escribano, Jaime;
    • González, Rubén;
    • Lozano, Sonia;
    • Huss, Sophie;
    • Santos‐Villarejo, Angel;
    • Martín‐Plaza, José Julio;
    • Mendoza, Alfonso;
    • Rebollo‐Lopez, María José;
    • Remuiñan‐Blanco, Modesto;
    • Lavandera, José Luis;
    • Pérez‐Herran, Esther;
    • Gamo‐Benito, Francisco Javier
    Publication type:
    Article

  • Repositioning: the fast track to new anti-malarial medicines?

    Published in:
    Malaria Journal, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1475-2875-13-143
    By:
    • Lotharius, Julie;
    • Gamo-Benito, Francisco Javier;
    • Angulo-Barturen, Iñigo;
    • Clark, Julie;
    • Connelly, Michele;
    • Ferrer-Bazaga, Santiago;
    • Parkinson, Tanya;
    • Viswanath, Pavithra;
    • Bandodkar, Balachandra;
    • Rautela, Nikhil;
    • Bharath, Sowmya;
    • Duffy, Sandra;
    • Avery, Vicky M.;
    • Möhrle, Jörg J.;
    • Guy, R. Kiplin;
    • Wells, Timothy
    Publication type:
    Article