Works by Gamba, Paola

Results: 22

The Emerging Role of PCSK9 in the Pathogenesis of Alzheimer's Disease: A Possible Target for the Disease Treatment.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 24, p. 13637, doi. 10.3390/ijms252413637

By:

Testa, Gabriella;
Giannelli, Serena;
Staurenghi, Erica;
Cecci, Rebecca;
Floro, Lucrezia;
Gamba, Paola;
Sottero, Barbara;
Leonarduzzi, Gabriella

Publication type:

Article

Loading into Nanoparticles Improves Quercetin's Efficacy in Preventing Neuroinflammation Induced by Oxysterols.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0096795

By:

Testa, Gabriella;
Gamba, Paola;
Badilli, Ulya;
Gargiulo, Simona;
Maina, Marco;
Guina, Tina;
Calfapietra, Simone;
Biasi, Fiorella;
Cavalli, Roberta;
Poli, Giuseppe;
Leonarduzzi, Gabriella

Publication type:

Article

Predictive markers for clinical outcomes in a cohort of diabetic patients hospitalized for COVID-19.

Published in:

Diabetology & Metabolic Syndrome, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13098-022-00941-7

By:

Madaschi, Sara;
Resmini, Eugenia;
Bonfadini, Silvia;
Massari, Giulia;
Gamba, Paola;
Sandri, Marco;
Calza, Stefano;
Cimino, Elena;
Zarra, Emanuela;
Dotti, Silvia;
Mascadri, Cristina;
Agosti, Barbara;
Garrafa, Emirena;
Girelli, Angela

Publication type:

Article

Oxidized cholesterol as the driving force behind the development of Alzheimer's disease.

Published in:

Frontiers in Aging Neuroscience, 2015, v. 7, p. 1, doi. 10.3389/fnagi.2015.00119

By:

Gamba, Paola;
Testa, Gabriella;
Gargiulo, Simona;
Staurenghi, Erica;
Poli, Giuseppe;
Leonarduzzi, Gabriella

Publication type:

Article

Cholesterol oxidation products induce spots of beta-amyloid aggregation on neuronal cells and may potentiate the peptide neurotoxic effects: A molecular link between hypercholesterolemia and Alzheimer's disease

Published in:

2012

By:

Poli, Giuseppe;
Gamba, Paola;
Testa, Gabriella;
Gargiulo, Simona;
Guglielmotto, Michela;
Tamagno, Elena;
Leonarduzzi, Gabriella

Publication type:

Abstract

The link between altered cholesterol metabolism and Alzheimer's disease.

Published in:

Annals of the New York Academy of Sciences, 2012, v. 1259, n. 1, p. 54, doi. 10.1111/j.1749-6632.2012.06513.x

By:

Gamba, Paola;
Testa, Gabriella;
Sottero, Barbara;
Gargiulo, Simona;
Poli, Giuseppe;
Leonarduzzi, Gabriella

Publication type:

Article

Lipid peroxidation and inflammatory molecules as markers of coronary artery disease.

Published in:

Redox Report, 2007, v. 12, n. 1/2, p. 81, doi. 10.1179/135100007X162275

By:

Sottero, Barbara;
Pozzi, Roberto;
Leonarduzzi, Gabriella;
Aroasio, Emiliano;
Gamba, Paola;
Gargiulo, Simona;
Rabajoli, Filippo;
Ferrari, Fabio;
Lucchina, Pietro Greco;
Poli, Giuseppe

Publication type:

Article

Expression and synthesis of TGFβ1 is induced in macrophages by 9-oxononanoyl cholesterol, a major cholesteryl ester oxidation product.

Published in:

Biofactors, 2005, v. 24, n. 1-4, p. 209, doi. 10.1002/biof.5520240125

By:

Sottero, Barbara;
Gamba, Paola;
Longhi, Monica;
Robbesyn, Fanny;
Abuja, Peter M.;
Schaur, Rudolf J.;
Poli, Giuseppe;
Leonarduzzi, Gabriella

Publication type:

Article

A Crosstalk Between Brain Cholesterol Oxidation and Glucose Metabolism in Alzheimer's Disease.

Published in:

Frontiers in Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnins.2019.00556

By:

Gamba, Paola;
Staurenghi, Erica;
Testa, Gabriella;
Giannelli, Serena;
Sottero, Barbara;
Leonarduzzi, Gabriella

Publication type:

Article

The role of oxysterols in vascular ageing.

Published in:

Journal of Physiology, 2016, v. 594, n. 8, p. 2095, doi. 10.1113/JP271168

By:

Gargiulo, Simona;
Gamba, Paola;
Testa, Gabriella;
Leonarduzzi, Gabriella;
Poli, Giuseppe

Publication type:

Article

Molecular signaling operated by a diet-compatible mixture of oxysterols in up-regulating CD36 receptor in CD68 positive cells.

Published in:

Molecular Nutrition & Food Research, 2010, v. 54, p. S31, doi. 10.1002/mnfr.200900493

By:

Leonarduzzi, Gabriella;
Gargiulo, Simona;
Gamba, Paola;
Perrelli, Maria-Giulia;
Castellano, Isabella;
Sapino, Anna;
Sottero, Barbara;
Poli, Giuseppe

Publication type:

Article

Molecular Signaling Involved in Oxysterol-Induced ß1-Integrin Over-Expression in Human Macrophages.

Published in:

International Journal of Molecular Sciences, 2012, v. 13, n. 11, p. 14278, doi. 10.3390/ijms131114278

By:

Gargiulo, Simona;
Gamba, Paola;
Testa, Gabriella;
Sottero, Barbara;
Maina, Marco;
Guina, Tina;
Biasi, Fiorella;
Poli, Giuseppe;
Leonarduzzi, Gabriella

Publication type:

Article

Relation between TLR4/NF-κB signaling pathway activation by 27-hydroxycholesterol and 4-hydroxynonenal, and atherosclerotic plaque instability.

Published in:

Aging Cell, 2015, v. 14, n. 4, p. 569, doi. 10.1111/acel.12322

By:

Gargiulo, Simona;
Gamba, Paola;
Testa, Gabriella;
Rossin, Daniela;
Biasi, Fiorella;
Poli, Giuseppe;
Leonarduzzi, Gabriella

Publication type:

Article

Up-regulation of β-amyloidogenesis in neuron-like human cells by both 24- and 27-hydroxycholesterol: protective effect of N-acetyl-cysteine.

Published in:

Aging Cell, 2014, v. 13, n. 3, p. 561, doi. 10.1111/acel.12206

By:

Gamba, Paola;
Guglielmotto, Michela;
Testa, Gabriella;
Monteleone, Debora;
Zerbinati, Chiara;
Gargiulo, Simona;
Biasi, Fiorella;
Iuliano, Luigi;
Giaccone, Giorgio;
Mauro, Alessandro;
Poli, Giuseppe;
Tamagno, Elena;
Leonarduzzi, Gabriella

Publication type:

Article

Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer's disease: three partners in crime.

Published in:

Aging Cell, 2011, v. 10, n. 3, p. 403, doi. 10.1111/j.1474-9726.2011.00681.x

By:

Gamba, Paola;
Leonarduzzi, Gabriella;
Tamagno, Elena;
Guglielmotto, Michela;
Testa, Gabriella;
Sottero, Barbara;
Gargiulo, Simona;
Biasi, Fiorella;
Mauro, Alessandro;
Viña, José;
Poli, Giuseppe

Publication type:

Article

The core-aldehyde 9-oxononanoyl cholesterol increases the level of transforming growth factor β1-specific receptors on promonocytic U937 cell membranes.

Published in:

Aging Cell, 2009, v. 8, n. 2, p. 77, doi. 10.1111/j.1474-9726.2009.00454.x

By:

Gargiulo, Simona;
Gamba, Paola;
Sottero, Barbara;
Biasi, Fiorella;
Chiarpotto, Elena;
Serviddio, Gaetano;
Vendemiale, Gianluigi;
Poli, Giuseppe;
Leonarduzzi, Gabriella

Publication type:

Article

Oxidation as a crucial reaction for cholesterol to induce tissue degeneration: CD36 overexpression in human promonocytic cells treated with a biologically relevant oxysterol mixture.

Published in:

Aging Cell, 2008, v. 7, n. 3, p. 375, doi. 10.1111/j.1474-9726.2008.00386.x

By:

Leonarduzzi, Gabriella;
Gamba, Paola;
Gargiulo, Simona;
Sottero, Barbara;
Kadl, Alexandra;
Biasi, Fiorella;
Chiarpotto, Elena;
Leitinger, Norbert;
Vendemiale, Gianluigi;
Serviddio, Gaetano;
Poli, Giuseppe

Publication type:

Article

Altered Brain Cholesterol Machinery in a Down Syndrome Mouse Model: A Possible Common Feature with Alzheimer's Disease.

Published in:

Antioxidants, 2024, v. 13, n. 4, p. 435, doi. 10.3390/antiox13040435

By:

Staurenghi, Erica;
Testa, Gabriella;
Leoni, Valerio;
Cecci, Rebecca;
Floro, Lucrezia;
Giannelli, Serena;
Barone, Eugenio;
Perluigi, Marzia;
Leonarduzzi, Gabriella;
Sottero, Barbara;
Gamba, Paola

Publication type:

Article

24-Hydroxycholesterol Induces Tau Proteasome-Dependent Degradation via the SIRT1/PGC1α/Nrf2 Pathway: A Potential Mechanism to Counteract Alzheimer's Disease.

Published in:

Antioxidants, 2023, v. 12, n. 3, p. 631, doi. 10.3390/antiox12030631

By:

Testa, Gabriella;
Giannelli, Serena;
Sottero, Barbara;
Staurenghi, Erica;
Giaccone, Giorgio;
Caroppo, Paola;
Gamba, Paola;
Leonarduzzi, Gabriella

Publication type:

Article

ApoE3 vs. ApoE4 Astrocytes: A Detailed Analysis Provides New Insights into Differences in Cholesterol Homeostasis.

Published in:

Antioxidants, 2022, v. 11, n. 11, p. 2168, doi. 10.3390/antiox11112168

By:

Staurenghi, Erica;
Leoni, Valerio;
Lo Iacono, Marco;
Sottero, Barbara;
Testa, Gabriella;
Giannelli, Serena;
Leonarduzzi, Gabriella;
Gamba, Paola

Publication type:

Article

Cholesterol Dysmetabolism in Alzheimer's Disease: A Starring Role for Astrocytes?

Published in:

Antioxidants, 2021, v. 10, n. 12, p. 1890, doi. 10.3390/antiox10121890

By:

Staurenghi, Erica;
Giannelli, Serena;
Testa, Gabriella;
Sottero, Barbara;
Leonarduzzi, Gabriella;
Gamba, Paola

Publication type:

Article

The Controversial Role of 24-S-Hydroxycholesterol in Alzheimer's Disease.

Published in:

Antioxidants, 2021, v. 10, n. 5, p. 740, doi. 10.3390/antiox10050740

By:

Gamba, Paola;
Giannelli, Serena;
Staurenghi, Erica;
Testa, Gabriella;
Sottero, Barbara;
Biasi, Fiorella;
Poli, Giuseppe;
Leonarduzzi, Gabriella;
Napolitano, Alessandra

Publication type:

Article