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Chloride channels as drug targets.
- Published in:
- 2009
- By:
- Publication type:
- journal article
The L467F-F508del Complex Allele Hampers Pharmacological Rescue of Mutant CFTR by Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Patients: The Value of the Ex Vivo Nasal Epithelial Model to Address Non-Responders to CFTR-Modulating Drugs.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 6, p. 3175, doi. 10.3390/ijms23063175
- By:
- Publication type:
- Article
Comprehensive Analysis of Combinatorial Pharmacological Treatments to Correct Nonsense Mutations in the CFTR Gene.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 11972, doi. 10.3390/ijms222111972
- By:
- Publication type:
- Article
Partial Rescue of F508del-CFTR Stability and Trafficking Defects by Double Corrector Treatment.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 10, p. 5262, doi. 10.3390/ijms22105262
- By:
- Publication type:
- Article
Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Small-molecule correctors of defective F508-CFTR cellular processing identified by high-throughput screening.
- Published in:
- Journal of Clinical Investigation, 2005, v. 115, n. 9, p. 2564, doi. 10.1172/JCI24898
- By:
- Publication type:
- Article
TMEM16A-TMEM16B chimaeras to investigate the structure-function relationship of calcium-activated chloride channels.
- Published in:
- Biochemical Journal, 2013, v. 452, n. 3, p. 443, doi. 10.1042/BJ20130348
- By:
- Publication type:
- Article
Ex vivo model predicted in vivo efficacy of CFTR modulator therapy in a child with rare genotype.
- Published in:
- Molecular Genetics & Genomic Medicine, 2021, v. 9, n. 4, p. 1, doi. 10.1002/mgg3.1656
- By:
- Publication type:
- Article
Novel tricyclic pyrrolo-quinolines as pharmacological correctors of the mutant CFTR chloride channel.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-34440-0
- By:
- Publication type:
- Article
Insensitivity of volume-sensitive chloride currents to chromones in human airway epithelial cells.
- Published in:
- British Journal of Pharmacology, 1998, v. 125, n. 6, p. 1382, doi. 10.1038/sj.bjp.0702225
- By:
- Publication type:
- Article
Intermolecular Interactions in the TMEM16A Dimer Controlling Channel Activity.
- Published in:
- Scientific Reports, 2016, p. 38788, doi. 10.1038/srep38788
- By:
- Publication type:
- Article
Goblet Cell Hyperplasia Requires High Bicarbonate Transport To Support Mucin Release.
- Published in:
- Scientific Reports, 2016, p. 36016, doi. 10.1038/srep36016
- By:
- Publication type:
- Article
Development of the Olfactory Epithelium and Nasal Glands in TMEM16A<sup>-/-</sup> and TMEM16A<sup>+/+</sup> Mice.
- Published in:
- PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0129171
- By:
- Publication type:
- Article
Upregulation of TMEM16A Protein in Bronchial Epithelial Cells by Bacterial Pyocyanin.
- Published in:
- PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0131775
- By:
- Publication type:
- Article
A novel missense mutation in ANO5/TMEM16E is causative for gnathodiaphyseal dyplasia in a large Italian pedigree.
- Published in:
- European Journal of Human Genetics, 2013, v. 21, n. 6, p. 613, doi. 10.1038/ejhg.2012.224
- By:
- Publication type:
- Article
Epithelial Sodium Channel Silencing as a Strategy to Correct the Airway Surface Fluid Deficit in Cystic Fibrosis.
- Published in:
- American Journal of Respiratory Cell & Molecular Biology, 2013, v. 49, n. 3, p. 445, doi. 10.1165/rcmb.2012-0408OC
- By:
- Publication type:
- Article
Epithelial Sodium Channel Inhibition in Primary Human Bronchial Epithelia by Transfected siRNA.
- Published in:
- American Journal of Respiratory Cell & Molecular Biology, 2009, v. 40, n. 2, p. 211, doi. 10.1165/rcmb.2007-0456OC
- By:
- Publication type:
- Article
Phenylhydrazones as Correctors of a Mutant Cystic Fibrosis Transmembrane Conductance Regulator.
- Published in:
- Archiv der Pharmazie, 2016, v. 349, n. 2, p. 112, doi. 10.1002/ardp.201500352
- By:
- Publication type:
- Article
Bioactive Thymosin Alpha-1 Does Not Influence F508del-CFTR Maturation and Activity.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46639-1
- By:
- Publication type:
- Article
Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-42751-4
- By:
- Publication type:
- Article
Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6).
- Published in:
- FASEB Journal, 2015, v. 29, n. 1, p. 152, doi. 10.1096/fj.14-258541
- By:
- Publication type:
- Article
Correspondence.
- Published in:
- American Journal of Respiratory & Critical Care Medicine, 2006, v. 173, n. 6, p. 685
- By:
- Publication type:
- Article
Gelsolin Secretion in Interleukin-4--treated Bronchial Epithelia and in Asthmatic Airways.
- Published in:
- American Journal of Respiratory & Critical Care Medicine, 2005, v. 172, n. 9, p. 1090, doi. 10.1164/rccm.200409-1185OC
- By:
- Publication type:
- Article
Analysis of inhibitors of the anoctamin‐1 chloride channel (transmembrane member 16A, TMEM16A) reveals indirect mechanisms involving alterations in calcium signalling.
- Published in:
- British Journal of Pharmacology, 2023, v. 180, n. 6, p. 775, doi. 10.1111/bph.15995
- By:
- Publication type:
- Article
Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms.
- Published in:
- Journal of Physiology, 2015, v. 593, n. 17, p. 3829, doi. 10.1113/JP270691
- By:
- Publication type:
- Article
Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia.
- Published in:
- Journal of Physiology, 2012, v. 590, n. 23, p. 6141, doi. 10.1113/jphysiol.2012.240838
- By:
- Publication type:
- Article
The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels.
- Published in:
- Experimental Physiology, 2012, v. 97, n. 2, p. 177, doi. 10.1113/expphysiol.2011.058198
- By:
- Publication type:
- Article
Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation.
- Published in:
- Scientific Reports, 2015, p. 12138, doi. 10.1038/srep12138
- By:
- Publication type:
- Article
Ionocytes and CFTR Chloride Channel Expression in Normal and Cystic Fibrosis Nasal and Bronchial Epithelial Cells.
- Published in:
- Cells (2073-4409), 2020, v. 9, n. 9, p. 2090, doi. 10.3390/cells9092090
- By:
- Publication type:
- Article
Intrinsic Abnormalities of Cystic Fibrosis Airway Connective Tissue Revealed by an In Vitro 3D Stromal Model.
- Published in:
- Cells (2073-4409), 2020, v. 9, n. 6, p. 1371, doi. 10.3390/cells9061371
- By:
- Publication type:
- Article
Two CFTR mutations within codon 970 differently impact on the chloride channel functionality.
- Published in:
- Human Mutation, 2019, v. 40, n. 6, p. 742, doi. 10.1002/humu.23741
- By:
- Publication type:
- Article
Speeding Up the Identification of Cystic Fibrosis Transmembrane Conductance Regulator-Targeted Drugs: An Approach Based on Bioinformatics Strategies and Surface Plasmon Resonance.
- Published in:
- Molecules, 2018, v. 23, n. 1, p. 120, doi. 10.3390/molecules23010120
- By:
- Publication type:
- Article
Asymmetric 4-Aryl-1,4-dihydropyridines Potentiate Mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).
- Published in:
- ChemMedChem, 2012, v. 7, n. 10, p. 1799, doi. 10.1002/cmdc.201200311
- By:
- Publication type:
- Article
Cystic fibrosis: Current topics, J.A. Dodge, D.J.H. Brock, and J.H. Widdicombe, eds., New York: John Wiley & Sons, 1994, 354 pages, $99.95.
- Published in:
- Genetic Epidemiology, 1995, v. 12, n. 4, p. 431, doi. 10.1002/gepi.1370120410
- By:
- Publication type:
- Article