Works by Gaal, Luc

Results: 134

A red yeast rice-olive extract supplement reduces biomarkers of oxidative stress, OxLDL and Lp-PLA<sub>2</sub>, in subjects with metabolic syndrome: a randomised, double-blind, placebo-controlled trial.

Published in:

2017

By:

Hermans, Nina;
Van der Auwera, Anastasia;
Breynaert, Annelies;
Verlaet, Annelies;
De Bruyne, Tess;
Luc Van Gaal;
Pieters, Luc;
Verhoeven, Veronique;
Van Gaal, Luc

Publication type:

journal article

The Effect of Lifestyle Interventions on Excess Ectopic Fat Deposition Measured by Noninvasive Techniques in Overweight and Obese Adults: A Systematic Review and Meta-Analysis.

Published in:

Journal of Physical Activity & Health, 2016, v. 13, n. 6, p. 671, doi. 10.1123/jpah.2015-0560

By:

Hens, Wendy;
Taeymans, Jan;
Cornelis, Justien;
Gielen, Jan;
Van Gaal, Luc;
Vissers, Dirk

Publication type:

Article

A Case–Control Study Supports Genetic Contribution of the PON Gene Family in Obesity and Metabolic Dysfunction Associated Steatotic Liver Disease.

Published in:

Antioxidants, 2024, v. 13, n. 9, p. 1051, doi. 10.3390/antiox13091051

By:

Van Dijck, Evelien;
Diels, Sara;
Fransen, Erik;
Cremers, Tycho Canter;
Verrijken, An;
Dirinck, Eveline;
Hoischen, Alexander;
Vandeweyer, Geert;
Vanden Berghe, Wim;
Van Gaal, Luc;
Francque, Sven;
Van Hul, Wim

Publication type:

Article

Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension.

Published in:

Diabetes, Obesity & Metabolism, 2022, v. 24, n. 8, p. 1553, doi. 10.1111/dom.14725

By:

Wilding, John P. H.;
Batterham, Rachel L.;
Davies, Melanie;
Van Gaal, Luc F.;
Kandler, Kristian;
Konakli, Katerina;
Lingvay, Ildiko;
McGowan, Barbara M.;
Oral, Tugce Kalayci;
Rosenstock, Julio;
Wadden, Thomas A.;
Wharton, Sean;
Yokote, Koutaro;
Kushner, Robert F.

Publication type:

Article

Efficacy and safety of high‐dose glucagon‐like peptide‐1, glucagon‐like peptide‐1/glucose‐dependent insulinotropic peptide, and glucagon‐like peptide‐1/glucagon receptor agonists in type 2 diabetes.

Published in:

Diabetes, Obesity & Metabolism, 2022, v. 24, n. 5, p. 788, doi. 10.1111/dom.14640

By:

De Block, Christophe E. M.;
Dirinck, Eveline;
Verhaegen, Ann;
Van Gaal, Luc F.

Publication type:

Article

Features of oral glucose tolerance tests in patients after Roux-en-Y gastric bypass with and without hypoglycaemia symptoms in daily life: It's all about speed.

Published in:

Diabetes, Obesity & Metabolism, 2020, v. 22, n. 11, p. 2107, doi. 10.1111/dom.14130

By:

Mariën, Ilke;
De Block, Christophe;
Verrijken, An;
Van Dessel, Kristof;
Peiffer, Frida;
Verhaegen, Ann;
Hubens, Guy;
Van Gaal, Luc;
Dirinck, Eveline

Publication type:

Article

Clinical outcomes with canagliflozin according to baseline body mass index: results from post hoc analyses of the CANVAS Program.

Published in:

Diabetes, Obesity & Metabolism, 2020, v. 22, n. 4, p. 530, doi. 10.1111/dom.13920

By:

Ohkuma, Toshiaki;
Van Gaal, Luc;
Shaw, Wayne;
Mahaffey, Kenneth W.;
Zeeuw, Dick;
Matthews, David R.;
Perkovic, Vlado;
Neal, Bruce

Publication type:

Article

Can Bariatric Surgery be Considered Standard Therapy to Treat Type 2 Diabetes?

Published in:

European Endocrinology, 2013, v. 9, n. 2, p. 86

By:

Meyvis, Karen;
Block, Christophe De;
Van Gaal, Luc F.

Publication type:

Article

NAFLD in type 1 diabetes: overrated or underappreciated?

Published in:

Therapeutic Advances in Endocrinology & Metabolism, 2021, p. 1, doi. 10.1177/20420188211055557

By:

Mertens, Jonathan;
Van Gaal, Luc F.;
Francque, Sven M.;
De Block, Christophe

Publication type:

Article

Therapeutic approaches for non-alcoholic steatohepatitis.

Published in:

Therapeutic Advances in Endocrinology & Metabolism, 2021, p. 1, doi. 10.1177/20420188211034300

By:

Van Gaal, Luc F.;
Mertens, Jonathan;
Francque, Sven;
De Block, Christophe

Publication type:

Article

Predicting type 2 diabetes mellitus: a comparison between the FINDRISC score and the metabolic syndrome.

Published in:

Diabetology & Metabolic Syndrome, 2018, v. 10, n. 1, p. 1, doi. 10.1186/s13098-018-0310-0

By:

Meijnikman, Abraham S.;
De Block, Christophe E. M.;
Verrijken, An;
Mertens, Ilse;
Van Gaal, Luc F.

Publication type:

Article

Foreword.

Published in:

International Journal of Obesity & Related Metabolic Disorders, 2000, v. 24, p. S1, doi. 10.1038/sj.ijo.0801322

By:

Van Gaal, Luc F;
Scheen, Andre J

Publication type:

Article

Lixisenatide Treatment for Older Patients with Type 2 Diabetes Mellitus Uncontrolled on Oral Antidiabetics: Meta-Analysis of Five Randomized Controlled Trials.

Published in:

Advances in Therapy, 2014, v. 31, n. 8, p. 861, doi. 10.1007/s12325-014-0146-4

By:

Hanefeld, Markolf;
Berria, Rachele;
Lin, Jay;
Aronson, Ronnie;
Darmon, Patrice;
Evans, Marc;
Gaal, Luc

Publication type:

Article

Unsupervised Exercise Training Was Not Found to Improve the Metabolic Health or Phenotype over a 6-Month Dietary Intervention: A Randomised Controlled Trial with an Embedded Economic Analysis.

Published in:

International Journal of Environmental Research & Public Health, 2021, v. 18, n. 15, p. 8004, doi. 10.3390/ijerph18158004

By:

Hens, Wendy;
Vissers, Dirk;
Verhaeghe, Nick;
Gielen, Jan;
Van Gaal, Luc;
Taeymans, Jan

Publication type:

Article

A Preliminary Link between Hydroxylated Metabolites of Polychlorinated Biphenyls and Free Thyroxin in Humans.

Published in:

International Journal of Environmental Research & Public Health, 2016, v. 13, n. 4, p. 421, doi. 10.3390/ijerph13040421

By:

Dirinck, Eveline;
Dirtu, Alin C.;
Malarvannan, Govindan;
Covaci, Adrian;
Jorens, Philippe G.;
Van Gaal, Luc F.

Publication type:

Article

A Delphi study to construct a CanMEDS competence based inventory applicable for workplace assessment.

Published in:

BMC Medical Education, 2012, v. 12, n. 1, p. 1, doi. 10.1186/1472-6920-12-86

By:

Michels, Nele RM;
Denekens, Joke;
Driessen, Erik W.;
Van Gaal, Luc F.;
Bossaert, Leo L.;
De Winter, Benedicte Y.

Publication type:

Article

Mechanisms linking obesity with cardiovascular disease.

Published in:

Nature, 2006, v. 444, n. 7121, p. 875, doi. 10.1038/nature05487

By:

Van Gaal, Luc F.;
Mertens, Ilse L.;
De Block, Christophe E.

Publication type:

Article

Non-Alcoholic Steatohepatitis Decreases Microsomal Liver Function in the Absence of Fibrosis.

Published in:

Biomedicines, 2020, v. 8, n. 12, p. 546, doi. 10.3390/biomedicines8120546

By:

Verlinden, Wim;
Van Mieghem, Eugénie;
Depauw, Laura;
Vanwolleghem, Thomas;
Vonghia, Luisa;
Weyler, Jonas;
Driessen, Ann;
Callens, Dirk;
Roosens, Laurence;
Dirinck, Eveline;
Verrijken, An;
Gaal, Luc Van;
Francque, Sven

Publication type:

Article

Accurate non‐invasive diagnosis and staging of non‐alcoholic fatty liver disease using the urinary steroid metabolome.

Published in:

Alimentary Pharmacology & Therapeutics, 2020, v. 51, n. 11, p. 1188, doi. 10.1111/apt.15710

By:

Moolla, Ahmad;
Boer, Jasper;
Pavlov, David;
Amin, Amin;
Taylor, Angela;
Gilligan, Lorna;
Hughes, Beverly;
Ryan, John;
Barnes, Eleanor;
Hassan‐Smith, Zaki;
Grove, Jane;
Aithal, Guruprasad P.;
Verrijken, An;
Francque, Sven;
Van Gaal, Luc;
Armstrong, Matthew J.;
Newsome, Phillip N.;
Cobbold, Jeremy F.;
Arlt, Wiebke;
Biehl, Michael

Publication type:

Article

Effect of semaglutide on liver enzymes and markers of inflammation in subjects with type 2 diabetes and/or obesity.

Published in:

Alimentary Pharmacology & Therapeutics, 2019, v. 50, n. 2, p. 193, doi. 10.1111/apt.15316

By:

Newsome, Philip;
Francque, Sven;
Harrison, Stephen;
Ratziu, Vlad;
Van Gaal, Luc;
Calanna, Salvatore;
Hansen, Morten;
Linder, Martin;
Sanyal, Arun

Publication type:

Article

Can calculated total nitrogen replace Kjeldahl total nitrogen measurements in 24-h urine samples?

Published in:

Clinical Chemistry & Laboratory Medicine, 2018, v. 56, n. 11, p. 255, doi. 10.1515/cclm-2018-0144

By:

Peeters, Bart;
Dirinck, Eveline;
Van Gaal, Luc;
Roosens, Laurence

Publication type:

Article

Evaluation of a Role for NPY and NPY2R in the Pathogenesis of Obesity by Mutation and Copy Number Variation Analysis in Obese Children and Adolescents.

Published in:

Annals of Human Genetics, 2018, v. 82, n. 1, p. 1, doi. 10.1111/ahg.12211

By:

Aerts, Evi;
Geets, Ellen;
Sorber, Laure;
Beckers, Sigri;
Verrijken, An;
Massa, Guy;
Van Hoorenbeeck, Kim;
Verhulst, Stijn L.;
Van Gaal, Luc F.;
Van Hul, Wim

Publication type:

Article

Association Study and Mutation Analysis of Adiponectin Shows Association of Variants in APM1 with Complex Obesity in Women.

Published in:

Annals of Human Genetics, 2009, v. 73, n. 5, p. 492, doi. 10.1111/j.1469-1809.2009.00532.x

By:

Beckers, Sigri;
Peeters, Armand V.;
de Freitas, Fenna;
Mertens, Ilse L.;
Verhulst, Stijn L.;
Haentjens, Dominique;
Desager, Kristine N.;
Van Gaal, Luc F.;
Van Hul, Wim

Publication type:

Article

Incidence and predisposing factors for the development of disturbed glucose metabolism and DIabetes mellitus AFter Intensive Care admission: the DIAFIC study.

Published in:

2015

By:

Van Ackerbroeck, Sofie;
Schepens, Tom;
Janssens, Karolien;
Jorens, Philippe G.;
Verbrugghe, Walter;
Collet, Sandra;
Van Hoof, Viviane;
Van Gaal, Luc;
De Block, Christophe

Publication type:

journal article

Early Fasting Serum Glucose or Weight Reduction With Tirzepatide and Metabolic Outcomes in People With Type 2 Diabetes: A Post Hoc Analysis of the SURPASS Trials.

Published in:

Diabetes Care, 2025, v. 48, n. 5, p. 790, doi. 10.2337/dc24-2790

By:

Giorgino, Francesco;
Lingvay, Ildiko;
Van Gaal, Luc F.;
Sharma, Palash;
Rodríguez, Ángel;
Kiljański, Jacek;
Torcello-Gómez, Amelia;
Levine, Joshua A.

Publication type:

Article

Twenty-Year Progression Rate to Clinical Onset According to Autoantibody Profile, Age, and Genotype in a Registry-Based Group of Children and Adults With a First-Degree Relative With Type 1 Diabetes.

Published in:

2017

By:

Gorus, Frans K.;
Balti, Eric V.;
Messaaoui, Anissa;
Demeester, Simke;
Van Dalem, Annelien;
Costa, Olivier;
Dorchy, Harry;
Mathieu, Chantal;
Van Gaal, Luc;
Keymeulen, Bart;
Pipeleers, Daniël G.;
Weets, Ilse;
Belgian Diabetes Registry

Publication type:

journal article

Pharmacological Approaches in the Treatment and Maintenance of Weight Loss.

Published in:

2016

By:

Van Gaal, Luc;
Dirinck, Eveline

Publication type:

journal article

Advances in the Science, Treatment, and Prevention of the Disease of Obesity: Reflections From a Diabetes Care Editors' Expert Forum.

Published in:

2015

By:

Cefalu, William T.;
Bray, George A.;
Home, Philip D.;
Garvey, W. Timothy;
Klein, Samuel;
Pi-Sunyer, F. Xavier;
Hu, Frank B.;
Raz, Itamar;
Van Gaal, Luc;
Wolfe, Bruce M.;
Ryan, Donna H.

Publication type:

journal article

Weight Management in Type 2 Diabetes: Current and Emerging Approaches to Treatment.

Published in:

Diabetes Care, 2015, v. 38, n. 6, p. 1161, doi. 10.2337/dc14-1630

By:

Van Gaal, Luc;
Scheen, André

Publication type:

Article

Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi-like features.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 7, p. 3037, doi. 10.1172/JCI68035

By:

Bonnefond, Amélie;
Raimondo, Anne;
Stutzmann, Fanny;
Ghoussaini, Maya;
Ramachandrappa, Shwetha;
Bersten, David C.;
Durand, Emmanuelle;
Vatin, Vincent;
Balkau, Beverley;
Lantieri, Olivier;
Raverdy, Violeta;
Pattou, François;
Van Hul, Wim;
Van Gaal, Luc;
Peet, Daniel J.;
Weill, Jacques;
Miller, Jennifer L.;
Horber, Fritz;
Goldstone, Anthony P.;
Driscoll, Daniel J.

Publication type:

Article

CNV analysis and mutation screening indicate an important role for the NPY4R gene in human obesity.

Published in:

2016

By:

Aerts, Evi;
Beckers, Sigri;
Zegers, Doreen;
Van Hoorenbeeck, Kim;
Massa, Guy;
Verrijken, An;
Verhulst, Stijn L.;
Van Gaal, Luc F.;
Van Hul, Wim

Publication type:

journal article

SULF2 strongly prediposes to fasting and postprandial triglycerides in patients with obesity and type 2 diabetes mellitus.

Published in:

Obesity (19307381), 2014, v. 22, n. 5, p. 1309, doi. 10.1002/oby.20682

By:

Hassing, H. Carlijne;
Surendran, R. Preethi;
Derudas, Bruno;
Verrijken, An;
Francque, Sven M.;
Mooij, Hans L.;
Bernelot Moens, Sophie J.;
Hart, Leen M.'t;
Nijpels, Giel;
Dekker, Jacqueline M.;
Williams, Kevin Jon;
Stroes, Erik S. G.;
Van Gaal, Luc F.;
Staels, Bart;
Nieuwdorp, Max;
Dallinga ‐ Thie, Geesje M.

Publication type:

Article

Weight Loss and Sleep-Disordered Breathing in Childhood Obesity: Effects on Inflammation and Uric Acid.

Published in:

Obesity (19307381), 2012, v. 20, n. 1, p. 172, doi. 10.1038/oby.2011.282

By:

Van Hoorenbeeck, Kim;
Franckx, Hilde;
Debode, Patrick;
Aerts, Petra;
Wouters, Kristien;
Ramet, Jose;
Van Gaal, Luc F.;
Desager, Kristine N.;
De Backer, Wilfried A.;
Verhulst, Stijn L.

Publication type:

Article

Obesity and Persistent Organic Pollutants: Possible Obesogenic Effect of Organochlorine Pesticides and Polychlorinated Biphenyls.

Published in:

Obesity (19307381), 2011, v. 19, n. 4, p. 709, doi. 10.1038/oby.2010.133

By:

Dirinck, Eveline;
Jorens, Philippe G.;
Covaci, Adrian;
Geens, Tinne;
Roosens, Laurence;
Neels, Hugo;
Mertens, Ilse;
Gaal, Luc Van

Publication type:

Article

Identification of Three Novel Genetic Variants in the Melanocortin-3 Receptor of Obese Children.

Published in:

Obesity (19307381), 2011, v. 19, n. 1, p. 152, doi. 10.1038/oby.2010.127

By:

Zegers, Doreen;
Beckers, Sigri;
De Freitas, Fenna;
Peeters, Armand V.;
Mertens, Ilse L.;
Verhulst, Stijn L.;
Rooman, Raoul P.;
Timmermans, Jean-Pierre;
Desager, Kristine N.;
Massa, Guy;
Van Gaal, Luc F.;
Hul, Wim Van

Publication type:

Article

Early Response to Sibutramine in Patients Not Meeting Current Label Criteria: Preliminary Analysis of SCOUT Lead-in Period.

Published in:

Obesity (19307381), 2010, v. 18, n. 5, p. 987, doi. 10.1038/oby.2009.327

By:

Caterson, Ian;
Coutinho, Walmir;
Finer, Nick;
Van Gaal, Luc;
Maggioni, Aldo;
Torp-Pedersen, Christian;
Sharma, Arya M.;
Ge, Hong;
Santoro, Donatella;
Shepherd, Gillian;
James, Philip

Publication type:

Article

Low Fasting Triglycerides: Hallmark of the Healthy Large Hip?

Published in:

Obesity (19307381), 2009, v. 17, n. 8, p. 1621, doi. 10.1038/oby.2009.25

By:

Ruige, Johannes B.;
Gaal, Luc F. Van

Publication type:

Article

The Effect of Weight Loss on Sleep-disordered Breathing in Obese Teenagers.

Published in:

Obesity (19307381), 2009, v. 17, n. 6, p. 1178, doi. 10.1038/oby.2008.673

By:

Verhulst, Stijn L.;
Franckx, Hilde;
Van Gaal, Luc;
De Backer, Wilfried;
Desager, Kristine

Publication type:

Article

Analysis of Genetic Variations in the Resistin Gene Shows No Associations With Obesity in Women.

Published in:

Obesity (19307381), 2008, v. 16, n. 4, p. 905, doi. 10.1038/oby.2007.131

By:

Beckers, Sigri;
Peeters, Armand V.;
De Freitas, Fenna;
Mertens, Ilse L.;
Hendrickx, Jan-laap;
Van Gaal, Luc F.;
Van Hul, Wim

Publication type:

Article

A comparison of two insulin infusion protocols in the medical intensive care unit by continuous glucose monitoring.

Published in:

Annals of Intensive Care, 2016, v. 6, n. 1, p. 1, doi. 10.1186/s13613-016-0214-9

By:

Block, Christophe;
Rogiers, Peter;
Jorens, Philippe;
Schepens, Tom;
Scuffi, Cosimo;
Gaal, Luc

Publication type:

Article

Rare Heterozygous PCSK1 Variants in Human Obesity: The Contribution of the p.Y181H Variant and a Literature Review.

Published in:

Genes, 2022, v. 13, n. 10, p. N.PAG, doi. 10.3390/genes13101746

By:

Van Dijck, Evelien;
Beckers, Sigri;
Diels, Sara;
Huybrechts, Tammy;
Verrijken, An;
Van Hoorenbeeck, Kim;
Verhulst, Stijn;
Massa, Guy;
Van Gaal, Luc;
Van Hul, Wim

Publication type:

Article

Replication of the SH2B1 rs7498665 Association with Obesity in a Belgian Study Population.

Published in:

Obesity Facts: The European Journal of Obesity, 2011, v. 4, n. 6, p. 473, doi. 10.1159/000335305

By:

Beckers, Sigri;
Zegers, Doreen;
Van Gaal, Luc F.;
Van Hul, Wim

Publication type:

Article

Identification and Functional Characterization of Novel Mutations in the Melanocortin-4 Receptor.

Published in:

Obesity Facts: The European Journal of Obesity, 2010, v. 3, n. 5, p. 304, doi. 10.1159/000321565

By:

Beckers, Sigri;
Zegers, Doreen;
de Freitas, Fenna;
Peeters, Armand V.;
Verhulst, Stijn L.;
Massa, Guy;
Van Gaal, Luc F.;
Timmermans, Jean-Pierre;
Desager, Kristine N.;
Van Hul, Wim

Publication type:

Article

Effect of Long-Term Whole Body Vibration Training on Visceral Adipose Tissue: A Preliminary Report.

Published in:

Obesity Facts: The European Journal of Obesity, 2010, v. 3, n. 2, p. 93, doi. 10.1159/000301785

By:

Vissers, Dirk;
Verrijken, An;
Mertens, Ilse;
Van Gils, Caroline;
Van de Sompel, Annemie;
Truijen, Steven;
Van Gaal, Luc

Publication type:

Article

Pro-Inflammatory Cytokines but Not Endotoxin-Related Parameters Associate with Disease Severity in Patients with NAFLD.

Published in:

PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0166048

By:

du Plessis, Johannie;
Korf, Hannelie;
van Pelt, Jos;
Windmolders, Petra;
Vander Elst, Ingrid;
Verrijken, An;
Hubens, Guy;
Van Gaal, Luc;
Cassiman, David;
Nevens, Frederik;
Francque, Sven;
van der Merwe, Schalk

Publication type:

Article

Common variants in the gene for the serotonin receptor 6 ( HTR6) do not contribute to obesity.

Published in:

Journal of Genetics, 2010, v. 89, n. 4, p. 469, doi. 10.1007/s12041-010-0066-2

By:

Peeters, Armand;
Beckers, Sigri;
Verrijken, An;
Roevens, Peter;
Peeters, Pieter;
Gaal, Luc;
Hul, Wim

Publication type:

Article

Response to comment on Home et al. Insulin therapy in people with type 2 diabetes: opportunities and challenges? Diabetes care 2014;37:1499-1508.

Published in:

2014

By:

Home, Philip;
Riddle, Matthew;
Cefalu, William T;
Bailey, Clifford J;
Bretzel, Reinhard G;
Del Prato, Stefano;
Leroith, Derek;
Schernthaner, Guntram;
van Gaal, Luc;
Raz, Itamar

Publication type:

Letter

Insulin Therapy in People With Type 2 Diabetes: Opportunities and Challenges?

Published in:

2014

By:

Home, Philip;
Riddle, Matthew;
Cefalu, William T.;
Bailey, Clifford J.;
Bretzel, Reinhard G.;
Prato, Stefano del;
Leroith, Derek;
Schernthaner, Guntram;
van Gaal, Luc;
Raz, Itamar

Publication type:

Letter to the Editor

Exposure to Persistent Organic Pollutants: Relationship With Abnormal Glucose Metabolism and Visceral Adiposity.

Published in:

Diabetes Care, 2014, v. 37, n. 7, p. 1951, doi. 10.2337/dc13-2329

By:

Dirinck, Eveline L.;
Dirtu, Alin C.;
Govindan, Malarvannan;
Covaci, Adrian;
Van Gaal, Luc F.;
Jorens, Philippe G.

Publication type:

Article

Insulin Therapy in People With Type 2 Diabetes: Opportunities and Challenges?

Published in:

Diabetes Care, 2014, v. 37, n. 6, p. 1499, doi. 10.2337/dc13-2743

By:

Home, Philip;
Riddle, Matthew;
Cefalu, William T.;
Bailey, Clifford J.;
Bretzel, Reinhard G.;
Prato, Stefano del;
Leroith, Derek;
Schernthaner, Guntram;
van Gaal, Luc;
Raz, Itamar

Publication type:

Article