Works by GRUBER, JAN

Results: 37

LinAge2: providing actionable insights and benchmarking with epigenetic clocks.

Published in:

NPJ Aging, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41514-025-00221-4

By:

Fong, Sheng;
Denisov, Kirill A.;
Nefedova, Anastasiia A.;
Kennedy, Brian K.;
Gruber, Jan

Publication type:

Article

Effects of Lithium on Age-related Decline in Mitochondrial Turnover and Function in Caenorhabditis elegans.

Published in:

2014

By:

Tam, Zhi Yang;
Gruber, Jan;
Ng, Li Fang;
Halliwell, Barry;
Gunawan, Rudiyanto

Publication type:

Journal Article

Effects of Lithium on Age-related Decline in Mitochondrial Turnover and Function in Caenorhabditis elegans.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2014, v. 69, n. 7, p. 810, doi. 10.1093/gerona/glt210

By:

Tam, Zhi Yang;
Gruber, Jan;
Ng, Li Fang;
Halliwell, Barry;
Gunawan, Rudiyanto

Publication type:

Article

A concerted increase in readthrough and intron retention drives transposon expression during aging and senescence.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.87811

By:

Pabis, Kamil;
Barardo, Diogo;
Sirbu, Olga;
Selvarajoo, Kumar;
Gruber, Jan;
Kennedy, Brian K.

Publication type:

Article

Tomographic Measurements of Temperature Fluctuations in an Air Plasma Cutting Torch.

Published in:

Plasma Chemistry & Plasma Processing, 2017, v. 37, n. 3, p. 689, doi. 10.1007/s11090-017-9794-x

By:

Hlína, Jan;
Šonský, Jiří;
Gruber, Jan

Publication type:

Article

Chronic resveratrol intake reverses pro-inflammatory cytokine profile and oxidative DNA damage in ageing hybrid mice.

Published in:

Age (0161-9152), 2011, v. 33, n. 3, p. 229, doi. 10.1007/s11357-010-9174-4

By:

Wong, Yee;
Gruber, Jan;
Jenner, Andrew;
Tay, Francis;
Ruan, Runsheng

Publication type:

Article

LipidClock: A Lipid-Based Predictor of Biological Age.

Published in:

Frontiers in Aging, 2022, p. 1, doi. 10.3389/fragi.2022.828239

By:

Unfried, Maximilian;
Li Fang Ng;
Cazenave-Gassiot, Amaury;
Batchu, Krishna Chaithanya;
Kennedy, Brian K.;
Wenk, Markus R.;
Tolwinski, Nicholas;
Gruber, Jan

Publication type:

Article

WNT Signaling in Disease.

Published in:

Cells (2073-4409), 2019, v. 8, n. 8, p. 826, doi. 10.3390/cells8080826

By:

Ng, Li Fang;
Kaur, Prameet;
Bunnag, Nawat;
Suresh, Jahnavi;
Sung, Isabelle Chiao Han;
Tan, Qian Hui;
Gruber, Jan;
Tolwinski, Nicholas S.

Publication type:

Article

Maximizing signal-to-noise ratio in the random mutation capture assay.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 5, p. e35, doi. 10.1093/nar/gkr1221

By:

Poovathingal, Suresh Kumar;
Gruber, Jan;
Ng, Li Fang;
Halliwell, Barry;
Gunawan, Rudiyanto

Publication type:

Article

Inhibition of amyloid‐induced toxicity by ergothioneine in a transgenic Caenorhabditis elegans model.

Published in:

FEBS Letters, 2019, v. 593, n. 16, p. 2139, doi. 10.1002/1873-3468.13497

By:

Cheah, Irwin K.;
Ng, Li‐Theng;
Ng, Li‐Fang;
Lam, Vanessa Y.;
Gruber, Jan;
Huang, Cheryl Y.W.;
Goh, Fang‐Qin;
Lim, Keith H.C.;
Halliwell, Barry

Publication type:

Article

Commutative Watermarking-Encryption of Audio Data with Minimum Knowledge Verification.

Published in:

Advances in Multimedia, 2017, p. 1, doi. 10.1155/2017/5879257

By:

Schmitz, Roland;
Gruber, Jan

Publication type:

Article

The Role of Mitochondrial Non-Enzymatic Protein Acylation in Ageing.

Published in:

PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0168752

By:

Hong, Shin Yee;
Ng, Li Theng;
Ng, Li Fang;
Inoue, Takao;
Tolwinski, Nicholas S.;
Hagen, Thilo;
Gruber, Jan

Publication type:

Article

C. elegans miro-1 Mutation Reduces the Amount of Mitochondria and Extends Life Span.

Published in:

PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0153233

By:

Shen, Yanqing;
Ng, Li Fang;
Low, Natarie Pei Wen;
Hagen, Thilo;
Gruber, Jan;
Inoue, Takao

Publication type:

Article

Towards Healthy Longevity: Comprehensive Insights from Molecular Targets and Biomarkers to Biological Clocks.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 12, p. 6793, doi. 10.3390/ijms25126793

By:

Yusri, Khalishah;
Kumar, Sanjay;
Fong, Sheng;
Gruber, Jan;
Sorrentino, Vincenzo

Publication type:

Article

Developmental Drift and the Role of Wnt Signaling in Aging.

Published in:

Cancers, 2016, v. 8, n. 8, p. 73, doi. 10.3390/cancers8080073

By:

Gruber, Jan;
Zhuangli Yee;
Tolwinski, Nicholas S.

Publication type:

Article

Deceptively simple but simply deceptive –Caenorhabditis elegans lifespan studies: Considerations for aging and antioxidant effects

Published in:

FEBS Letters, 2009, v. 583, n. 21, p. 3377, doi. 10.1016/j.febslet.2009.09.051

By:

Gruber, Jan;
Ng, Li Fang;
Poovathingal, Suresh Kumar;
Halliwell, Barry

Publication type:

Article

Argumentation Schemes for Blockchain Deanonymisation.

Published in:

FinTech, 2024, v. 3, n. 2, p. 236, doi. 10.3390/fintech3020014

By:

Deuber, Dominic;
Gruber, Jan;
Humml, Merlin;
Ronge, Viktoria;
Scheler, Nicole

Publication type:

Article

A small-molecule Psora-4 acts as a caloric restriction mimetic to promote longevity in C. elegans.

Published in:

GeroScience, 2022, v. 44, n. 2, p. 1029, doi. 10.1007/s11357-021-00374-6

By:

Admasu, Tesfahun Dessale;
Barardo, Diogo;
Ng, Li Fang;
Batchu, Krishna Chaithanya;
Cazenave-Gassiot, Amaury;
Wenk, Markus R.;
Gruber, Jan

Publication type:

Article

Drug synergy as a strategy for compression of morbidity in a Caenorhabditis elegans model of Alzheimer's disease.

Published in:

GeroScience, 2020, v. 42, n. 3, p. 849, doi. 10.1007/s11357-020-00169-1

By:

Teo, Emelyne;
Fong, Sheng;
Tolwinski, Nicholas;
Gruber, Jan

Publication type:

Article

Clonal expansion of mitochondrial DNA deletions is a private mechanism of aging in long‐lived animals.

Published in:

Aging Cell, 2018, v. 17, n. 5, p. 1, doi. 10.1111/acel.12814

By:

Lakshmanan, Lakshmi Narayanan;
Yee, Zhuangli;
Ng, Li Fang;
Gunawan, Rudiyanto;
Halliwell, Barry;
Gruber, Jan

Publication type:

Article

The DrugAge database of aging-related drugs.

Published in:

Aging Cell, 2017, v. 16, n. 3, p. 594, doi. 10.1111/acel.12585

By:

Barardo, Diogo;
Thornton, Daniel;
Thoppil, Harikrishnan;
Walsh, Michael;
Sharifi, Samim;
Ferreira, Susana;
Anžič, Andreja;
Fernandes, Maria;
Monteiro, Patrick;
Grum, Tjaša;
Cordeiro, Rui;
De‐Souza, Evandro Araújo;
Budovsky, Arie;
Araujo, Natali;
Gruber, Jan;
Petrascheck, Michael;
Fraifeld, Vadim E.;
Zhavoronkov, Alexander;
Moskalev, Alexey;
Magalhães, João Pedro

Publication type:

Article

Limited antioxidant effect after consumption of a single dose of tomato sauce by young males, despite a rise in plasma lycopene.

Published in:

Free Radical Research, 2009, v. 43, n. 6, p. 622, doi. 10.1080/10715760902942816

By:

Lee, Chung-Yung Jetty;
Isaac, Helen B.;
Huang, Shan Hong;
Long, Lee Hua;
Wang, Huansong;
Gruber, Jan;
Ong, Choon Nam;
Kelly, Ronan P.;
Halliwell, Barry

Publication type:

Article

Context-Dependent Role of Mitochondrial Fusion-Fission in Clonal Expansion of mtDNA Mutations.

Published in:

PLoS Computational Biology, 2015, v. 11, n. 5, p. 1, doi. 10.1371/journal.pcbi.1004183

By:

Tam, Zhi Yang;
Gruber, Jan;
Halliwell, Barry;
Gunawan, Rudiyanto

Publication type:

Article

Stochastic Drift in Mitochondrial DNA Point Mutations: A Novel Perspective Ex Silico.

Published in:

PLoS Computational Biology, 2009, v. 5, n. 11, p. 1, doi. 10.1371/journal.pcbi.1000572

By:

Poovathingal, Suresh Kumar;
Gruber, Jan;
Halliwell, Barry;
Gunawan, Rudiyanto

Publication type:

Article

Psoralea corylifolia L. Inhibits Mitochondrial Complex I and Proteasome Activities in SH-SY5Y Cells.

Published in:

Annals of the New York Academy of Sciences, 2007, v. 1100, p. 486, doi. 10.1196/annals.1395.053

By:

TANG, SOON YEW;
GRUBER, JAN;
WONG, KIM PING;
HALLIWELL, BARRY

Publication type:

Article

Evidence for a Trade-Off between Survival and Fitness Caused by Resveratrol Treatment of Caenorhabditis elegans.

Published in:

Annals of the New York Academy of Sciences, 2007, v. 1100, p. 530, doi. 10.1196/annals.1395.059

By:

GRUBER, JAN;
TANG, SOON YEW;
HALLIWELL, BARRY

Publication type:

Article

Are mutagenic non D-loop direct repeat motifs in mitochondrial DNA under a negative selection pressure?

Published in:

Nucleic Acids Research, 2015, v. 43, n. 8, p. 4098, doi. 10.1093/nar/gkv299

By:

Lakshmanan, Lakshmi Narayanan;
Gruber, Jan;
Halliwell, Barry;
Gunawan, Rudiyanto

Publication type:

Article

Mathematical Modeling of the Role of Mitochondrial Fusion and Fission in Mitochondrial DNA Maintenance.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076230

By:

Tam, Zhi Yang;
Gruber, Jan;
Halliwell, Barry;
Gunawan, Rudiyanto

Publication type:

Article

Role of Direct Repeat and Stem-Loop Motifs in mtDNA Deletions: Cause or Coincidence?

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035271

By:

Lakshmanan, Lakshmi Narayanan;
Gruber, Jan;
Halliwell, Barry;
Gunawan, Rudiyanto

Publication type:

Article

Mitochondrial Changes in Ageing Caenorhabditis elegans -- What Do We Learn from Superoxide Dismutase Knockouts?

Published in:

PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0019444

By:

Jan Gruber;
Li Fang Ng;
Sheng Fong;
Yee Ting Wong;
Soon Ann Koh;
Ce-Belle Chen;
Guanghou Shui;
Wei Fun Cheong;
Schaffer, Sebastian;
Wenk, Markus R.;
Halliwell, Barry

Publication type:

Article

Inhibition of mTOR decreases insoluble proteins burden by reducing translation in C. elegans.

Published in:

Biogerontology, 2021, v. 22, n. 1, p. 101, doi. 10.1007/s10522-020-09906-7

By:

Yee, Zhuangli;
Lim, Shaun Hsien Yang;
Ng, Li Fang;
Gruber, Jan

Publication type:

Article

Identification of a previously undetected metabolic defect in the Complex II Caenorhabditis elegans mev- 1 mutant strain using respiratory control analysis.

Published in:

Biogerontology, 2017, v. 18, n. 2, p. 189, doi. 10.1007/s10522-016-9672-6

By:

Fong, Sheng;
Ng, Li;
Moore, Philip;
Halliwell, Barry;
Gruber, Jan

Publication type:

Article

Is mitochondrial DNA turnover slower than commonly assumed?

Published in:

Biogerontology, 2012, v. 13, n. 5, p. 557, doi. 10.1007/s10522-012-9390-7

By:

Poovathingal, Suresh;
Gruber, Jan;
Lakshmanan, LakshmiNarayanan;
Halliwell, Barry;
Gunawan, Rudiyanto

Publication type:

Article

Ageing in nematodes: do antioxidants extend lifespan in Caenorhabditis elegans?

Published in:

Biogerontology, 2010, v. 11, n. 1, p. 17, doi. 10.1007/s10522-009-9223-5

By:

Pun, Pamela;
Gruber, Jan;
Tang, Soon;
Schaffer, Sebastian;
Ong, Raphael;
Fong, Sheng;
Ng, Li;
Cheah, Irwin;
Halliwell, Barry

Publication type:

Article

Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model.

Published in:

Scientific Reports, 2016, p. 33781, doi. 10.1038/srep33781

By:

Fong, Sheng;
Teo, Emelyne;
Ng, Li Fang;
Chen, Ce-Belle;
Lakshmanan, Lakshmi Narayanan;
Tsoi, Sau Yee;
Moore, Philip Keith;
Inoue, Takao;
Halliwell, Barry;
Gruber, Jan

Publication type:

Article

Glutathione catabolism by Enterobacteriaceae species to hydrogen sulphide adversely affects the viability of host systems in the presence of 5′fluorodeoxyuridine.

Published in:

Molecular Microbiology, 2022, v. 117, n. 5, p. 1089, doi. 10.1111/mmi.14893

By:

Lim, Daniel Rui Xiang;
Chen, Yahua;
Ng, Li Fang;
Gruber, Jan;
Gan, Yunn‐Hwen

Publication type:

Article

Approaches for extending human healthspan: from antioxidants to healthspan pharmacology.

Published in:

Essays in Biochemistry, 2017, v. 61, n. 3, p. 389, doi. 10.1042/EBC20160091

By:

Gruber, Jan;
Halliwell, Barry

Publication type:

Article