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Deficiency of T-type voltage-gated calcium channels results in attenuated weight gain and improved endothelium-dependent dilatation of resistance vessels induced by a high-fat diet in mice.
- Published in:
- Journal of Physiology & Biochemistry, 2020, v. 76, n. 1, p. 135, doi. 10.1007/s13105-020-00728-2
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- Publication type:
- Article
Mathematical Model Predicts that Acceleration of Diabetic Wound Healing is Dependent on Spatial Distribution of VEGF-A mRNA (AZD8601).
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- Cellular & Molecular Bioengineering, 2021, v. 14, n. 4, p. 321, doi. 10.1007/s12195-021-00678-9
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- Publication type:
- Article
Corrigendum: Integrative model of the response of yeast to osmotic shock.
- Published in:
- 2006
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- Publication type:
- Erratum
Integrative model of the response of yeast to osmotic shock.
- Published in:
- Nature Biotechnology, 2005, v. 23, n. 8, p. 975, doi. 10.1038/nbt1114
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- Publication type:
- Article
Inhibition of the prostaglandin D2–GPR44/DP2 axis improves human islet survival and function.
- Published in:
- Diabetologia, 2020, v. 63, n. 7, p. 1355, doi. 10.1007/s00125-020-05138-z
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- Publication type:
- Article
Optimal Design in Population Kinetic Experiments by Set-Valued Methods.
- Published in:
- AAPS Journal, 2011, v. 13, n. 4, p. 495, doi. 10.1208/s12248-011-9291-8
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- Publication type:
- Article
Integrated experimental-computational analysis of a HepaRG liver-islet microphysiological system for human-centric diabetes research.
- Published in:
- PLoS Computational Biology, 2022, v. 18, n. 10, p. 1, doi. 10.1371/journal.pcbi.1010587
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- Publication type:
- Article
Digital twin predicting diet response before and after long-term fasting.
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- PLoS Computational Biology, 2022, v. 18, n. 9, p. 1, doi. 10.1371/journal.pcbi.1010469
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- Publication type:
- Article
A multi-scale digital twin for adiposity-driven insulin resistance in humans: diet and drug effects.
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- Diabetology & Metabolic Syndrome, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13098-023-01223-6
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- Publication type:
- Article
Network modeling of the transcriptional effects of copy number aberrations in glioblastoma.
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- Molecular Systems Biology, 2011, v. 7, n. 1, p. 1, doi. 10.1038/msb.2011.17
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- Publication type:
- Article
Models from experiments: combinatorial drug perturbations of cancer cells.
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- Molecular Systems Biology, 2008, v. 4, n. 1, p. 1, doi. 10.1038/msb.2008.53
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- Publication type:
- Article
Normoglycemia and physiological cortisone level maintain glucose homeostasis in a pancreas-liver microphysiological system.
- Published in:
- Communications Biology, 2024, p. 1, doi. 10.1038/s42003-024-06514-w
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- Publication type:
- Article
Systems biology reveals uncoupling beyond UCP1 in human white fat-derived beige adipocytes.
- Published in:
- NPJ Systems Biology & Applications, 2017, v. 3, n. 1, p. N.PAG, doi. 10.1038/s41540-017-0027-y
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- Publication type:
- Article
3D cell aggregates amplify diffusion signals.
- Published in:
- PLoS ONE, 2024, v. 19, n. 9, p. 1, doi. 10.1371/journal.pone.0310109
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- Publication type:
- Article
A case‐study of model‐informed drug development of a novel PCSK9 anti sense oligonucleotide. Part 1: First time in man to phase II.
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- CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1569, doi. 10.1002/psp4.12866
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- Publication type:
- Article
Model‐Based Analysis Reveals a Sustained and Dose‐Dependent Acceleration of Wound Healing by VEGF‐A mRNA (AZD8601).
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 7, p. 384, doi. 10.1002/psp4.12516
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- Publication type:
- Article
Input estimation for drug discovery using optimal control and Markov chain Monte Carlo approaches.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2016, v. 43, n. 2, p. 207, doi. 10.1007/s10928-016-9467-z
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- Publication type:
- Article
Modeling energy intake by adding homeostatic feedback and drug intervention.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2015, v. 42, n. 1, p. 79, doi. 10.1007/s10928-014-9399-4
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- Publication type:
- Article
A modeling approach for compounds affecting body composition.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2013, v. 40, n. 6, p. 651, doi. 10.1007/s10928-013-9337-x
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- Publication type:
- Article
Population pharmacokinetic modeling and deconvolution of enantioselective absorption of eflornithine in the rat.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2013, v. 40, n. 1, p. 117, doi. 10.1007/s10928-012-9293-x
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- Publication type:
- Article
Inhibition of SGLT2 Preserves Function and Promotes Proliferation of Human Islets Cells In Vivo in Diabetic Mice.
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- Biomedicines, 2022, v. 10, n. 2, p. 203, doi. 10.3390/biomedicines10020203
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- Publication type:
- Article
A Simple Mathematical Model of Adaptation to High Osmolarity in Yeast.
- Published in:
- In Silico Biology, 2006, v. 6, n. 3, p. 193
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- Publication type:
- Article
Effects of a novel potent melanin-concentrating hormone receptor 1 antagonist, AZD1979, on body weight homeostasis in mice and dogs.
- Published in:
- 2016
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- Publication type:
- journal article
Plasma Pharmacokinetics of N-Acetylgalactosamine-Conjugated Small-Interfering Ribonucleic Acids (GalNAc-Conjugated siRNAs).
- Published in:
- Clinical Pharmacokinetics, 2023, v. 62, n. 12, p. 1661, doi. 10.1007/s40262-023-01314-7
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- Publication type:
- Article
Unlock the Thermogenic Potential of Adipose Tissue: Pharmacological Modulation and implications for Treatment of Diabetes and Obesity.
- Published in:
- Frontiers in Endocrinology, 2015, v. 6, p. 1, doi. 10.3389/fendo.2015.00174
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- Publication type:
- Article
An oral antisense oligonucleotide for PCSK9 inhibition.
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- Science Translational Medicine, 2021, v. 13, n. 593, p. 1, doi. 10.1126/scitranslmed.abe9117
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- Publication type:
- Article
Automated analysis of routinely generated preclinical pharmacokinetic and pharmacodynamic data.
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- Journal of Bioinformatics & Computational Biology, 2014, v. 12, n. 3, p. 1450010-1, doi. 10.1142/S0219720014500103
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- Publication type:
- Article
ODEion - A SOFTWARE MODULE FOR STRUCTURAL IDENTIFICATION OF ORDINARY DIFFERENTIAL EQUATIONS.
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- Journal of Bioinformatics & Computational Biology, 2014, v. 12, n. 1, p. -1, doi. 10.1142/S0219720013500157
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- Publication type:
- Article
MODELING YEAST OSMOADAPTATION AT DIFFERENT LEVELS OF RESOLUTION.
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- Journal of Bioinformatics & Computational Biology, 2013, v. 11, n. 2, p. 1, doi. 10.1142/S0219720013300013
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- Publication type:
- Article
Benchmarks for identification of ordinary differential equations from time series data.
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- Bioinformatics, 2009, v. 25, n. 6, p. 780, doi. 10.1093/bioinformatics/btp050
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- Publication type:
- Article
1953-P: PPARγ Agonism and FGF-21 Synergize to Robustly Induce Browning of White Fat.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1953-P
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- Publication type:
- Article