Works by Gütschow, Michael

Results: 106
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    Macrocyclic Protease Inhibitors with Reduced Peptide Character.

    Published in:
    Angewandte Chemie, 2014, v. 126, n. 30, p. 7962, doi. 10.1002/ange.201404301
    By:
    • Chua, Krystle C. H.;
    • Pietsch, Markus;
    • Zhang, Xiaozhou;
    • Hautmann, Stephanie;
    • Chan, Hon Y.;
    • Bruning, John B.;
    • Gütschow, Michael;
    • Abell, Andrew D.
    Publication type:
    Article
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    Polyketide Skeletons from the Marine Alga-Derived Fungus Coniothyrium cereale.

    Published in:
    European Journal of Organic Chemistry, 2012, v. 2012, n. 31, p. 6197, doi. 10.1002/ejoc.201200700
    By:
    • Elsebai, Mahmoud Fahmi;
    • Nazir, Mamona;
    • Kehraus, Stefan;
    • Egereva, Ekaterina;
    • Ioset, Karine Ndjoko;
    • Marcourt, Laurence;
    • Jeannerat, Damien;
    • Gütschow, Michael;
    • Wolfender, Jean-Luc;
    • König, Gabriele M.
    Publication type:
    Article
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    Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28515-1
    By:
    • Ng, Yuen Lam Dora;
    • Ramberger, Evelyn;
    • Bohl, Stephan R.;
    • Dolnik, Anna;
    • Steinebach, Christian;
    • Conrad, Theresia;
    • Müller, Sina;
    • Popp, Oliver;
    • Kull, Miriam;
    • Haji, Mohamed;
    • Gütschow, Michael;
    • Döhner, Hartmut;
    • Walther, Wolfgang;
    • Keller, Ulrich;
    • Bullinger, Lars;
    • Mertins, Philipp;
    • Krönke, Jan
    Publication type:
    Article
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    New Cathepsin Inhibitors to Explore the Fluorophilic Properties of the S.

    Published in:
    Chemistry - A European Journal, 2011, v. 17, n. 19, p. 5256, doi. 10.1002/chem.201100113
    By:
    • Fustero, Santos;
    • Rodrigo, Vanessa;
    • Sánchez-Roselló, María;
    • del Pozo, Carlos;
    • Timoneda, Joaquín;
    • Frizler, Maxim;
    • Sisay, Mihiret T.;
    • Bajorath, Jürgen;
    • Calle, Luis P.;
    • Cañada, F. Javier;
    • Jiménez-Barbero, Jesús;
    • Gütschow, Michael
    Publication type:
    Article
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    Cell-permeable high-affinity tracers for G<sub>q</sub> proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors.

    Published in:
    2020
    By:
    • Kuschak, Markus;
    • Namasivayam, Vigneshwaran;
    • Rafehi, Muhammad;
    • Voss, Jan H.;
    • Garg, Jaspal;
    • Schlegel, Jonathan G.;
    • Abdelrahman, Aliaa;
    • Kehraus, Stefan;
    • Reher, Raphael;
    • Küppers, Jim;
    • Sylvester, Katharina;
    • Hinz, Sonja;
    • Matthey, Michaela;
    • Wenzel, Daniela;
    • Fleischmann, Bernd K.;
    • Pfeifer, Alexander;
    • Inoue, Asuka;
    • Gütschow, Michael;
    • König, Gabriele M.;
    • Müller, Christa E.
    Publication type:
    journal article
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    Mapping the S1 and S1' subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents.

    Published in:
    PLoS Neglected Tropical Diseases, 2020, v. 14, n. 3, p. 1, doi. 10.1371/journal.pntd.0007755
    By:
    • Cianni, Lorenzo;
    • Lemke, Carina;
    • Gilberg, Erik;
    • Feldmann, Christian;
    • Rosini, Fabiana;
    • Rocho, Fernanda dos Reis;
    • Ribeiro, Jean F. R.;
    • Tezuka, Daiane Y.;
    • Lopes, Carla D.;
    • de Albuquerque, Sérgio;
    • Bajorath, Jürgen;
    • Laufer, Stefan;
    • Leitão, Andrei;
    • Gütschow, Michael;
    • Montanari, Carlos A.
    Publication type:
    Article
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    Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes.

    Published in:
    Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 515, doi. 10.1080/14756366.2021.2024527
    By:
    • Benýšek, Jakub;
    • Buša, Michal;
    • Rubešová, Petra;
    • Fanfrlík, Jindřich;
    • Lepšík, Martin;
    • Brynda, Jiří;
    • Matoušková, Zuzana;
    • Bartz, Ulrike;
    • Horn, Martin;
    • Gütschow, Michael;
    • Mareš, Michael
    Publication type:
    Article
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    Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20418-3
    By:
    • Hermes, Cornelia;
    • Richarz, René;
    • Wirtz, Daniel A.;
    • Patt, Julian;
    • Hanke, Wiebke;
    • Kehraus, Stefan;
    • Voß, Jan Hendrik;
    • Küppers, Jim;
    • Ohbayashi, Tsubasa;
    • Namasivayam, Vigneshwaran;
    • Alenfelder, Judith;
    • Inoue, Asuka;
    • Mergaert, Peter;
    • Gütschow, Michael;
    • Müller, Christa E.;
    • Kostenis, Evi;
    • König, Gabriele M.;
    • Crüsemann, Max
    Publication type:
    Article
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