Works by Göbel, Michael W.

Results: 33

Click Conjugates of Artificial Ribonucleases: Sequence Specific Cleavage with Multiple Turnover.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 30, p. 1, doi. 10.1002/chem.202500451

By:

Weber, Sandra;
Weinrich, Timo;
Scheffer, Ute;
Kalden, Elisabeth;
Göbel, Michael W.

Publication type:

Article

Spin‐Labeled Riboswitch Synthesized from a Protected TPA Phosphoramidite Building Block.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 56, p. 1, doi. 10.1002/chem.202201822

By:

Kaiser, Frank;
Endeward, Burkhard;
Collauto, Alberto;
Scheffer, Ute;
Prisner, Thomas F.;
Göbel, Michael W.

Publication type:

Article

Synthesis of a Cytidine Phosphoramidite with Protected Nitroxide Spin Label for EPR Experiments with RNA.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 3, p. 491, doi. 10.1002/ejoc.201601174

By:

Weinrich, Timo;
Gränz, Markus;
Grünewald, Christian;
Prisner, Thomas F.;
Göbel, Michael W.

Publication type:

Article

Photolabile Protecting Groups for Nitroxide Spin Labels.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 19, p. 4037, doi. 10.1002/ejoc.201301692

By:

Seven, Ibrahim;
Weinrich, Timo;
Gränz, Markus;
Grünewald, Christian;
Brüß, Silke;
Krstić, Ivan;
Prisner, Thomas F.;
Heckel, Alexander;
Göbel, Michael W.

Publication type:

Article

Modular Solid-Phase Synthesis of Teroxazoles as a Class of α-Helix Mimetics.

Published in:

European Journal of Organic Chemistry, 2012, v. 2012, n. 17, p. 3270, doi. 10.1002/ejoc.201200339

By:

Pinto Gomes, Cristiano;
Metz, Alexander;
Bats, Jan W.;
Gohlke, Holger;
Göbel, Michael W.

Publication type:

Article

A Cytidine Phosphoramidite with Protected Nitroxide Spin Label: Synthesis of a Full‐Length TAR RNA and Investigation by In‐Line Probing and EPR Spectroscopy.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 23, p. 6202, doi. 10.1002/chem.201800167

By:

Weinrich, Timo;
Jaumann, Eva A.;
Scheffer, Ute;
Prisner, Thomas F.;
Göbel, Michael W.

Publication type:

Article

Directed Crosslinking of RNA by Glutathione‐Triggered PNA‐Quinone‐Methide‐Conjugates.

Published in:

European Journal of Organic Chemistry, 2022, v. 2022, n. 33, p. 1, doi. 10.1002/ejoc.202200318

By:

Hornung, Jan‐Erik;
Weinrich, Timo;
Göbel, Michael W.

Publication type:

Article

RNA Hydrolysis by Heterocyclic Amidines and Guanidines: Parameters Affecting Reactivity.

Published in:

European Journal of Organic Chemistry, 2021, v. 2021, n. 46, p. 6358, doi. 10.1002/ejoc.202100950

By:

Danneberg, Friederike;
Westemeier, Hauke;
Horx, Philip;
Zellmann, Felix;
Dörr, Kathrin;
Kalden, Elisabeth;
Zeiger, Mirco;
Akpinar, Abdullah;
Berger, Robert;
Göbel, Michael W.

Publication type:

Article

On Facts and Artefacts: The Difficulty to Evaluate an Artificial Nuclease.

Published in:

Helvetica Chimica Acta, 2003, v. 86, n. 11, p. 3740

By:

Stefan Pitsch;
Ute Scheffer;
Markus Hey;
Andreas Strick;
Michael W. Göbel

Publication type:

Article

Substitution of Adenine by Purine-2,6-diamine Improves the Nonenzymatic Oligomerization of Ribonucleotides on Templates Containing Thymidine.

Published in:

Helvetica Chimica Acta, 2000, v. 83, n. 9, p. 2541, doi. 10.1002/1522-2675(20000906)83:9<2541::AID-HLCA2541>3.0.CO;2-8

By:

Hartel, Christian;
Göbel, Michael W.

Publication type:

Article

Acridine-Labeled Primers as Tools for the Study of Nonenzymatic RNA Oligomerization.

Published in:

Helvetica Chimica Acta, 1998, v. 81, n. 5-8, p. 1156, doi. 10.1002/hlca.19980810528

By:

Kurz, Markus;
Göbel, Karin;
Hartel, Christian;
Göbel, Michael W.

Publication type:

Article

Hydrolytical Cleavage of TAR-RNA, the trans-Activation Responsive Region of HIV-1, by a Bis(guanidinium) Catalyst Attached to Arginine.

Published in:

Helvetica Chimica Acta, 1996, v. 79, n. 7, p. 1967, doi. 10.1002/hlca.19960790719

By:

Kurz, Kristina;
Göbel, Michael W.

Publication type:

Article

A C<sub>2</sub>-Chiral Bis(amidinium) Catalyst for a Diels-Alder Reaction Constituting the Key Step of the Quinkert-Dane Estrone Synthesis.

Published in:

European Journal of Organic Chemistry, 2003, v. 2003, n. 9, p. 1661, doi. 10.1002/ejoc.200200635

By:

Svetlana B. Tsogoeva;
Gerd Dürner;
Michael Bolte;
Michael W. Göbel

Publication type:

Article

Enantioselvctive Synthesis of Non- Natural Aromatic α-Amino Acids.

Published in:

Chemistry - A European Journal, 2007, v. 13, n. 36, p. 10017, doi. 10.1002/chem.200790140

By:

Krebs, Andreas;
Ludwig, Verena;
Pfizer, José;
Dürner, Gerd;
Göbel, Michael W.

Publication type:

Article

Enantioselective Synthesis of Non-Natural Aromatic α-Amino Acids.

Published in:

Chemistry - A European Journal, 2004, v. 10, n. 2, p. 544, doi. 10.1002/chem.200305421

By:

Andreas Krebs;
Verena Ludwig;
José Pfizer;
Gerd Dürner;
Michael W. Göbel

Publication type:

Article

Tripeptides from Synthetic Amino Acids Block the Tat-TAR Association and Slow Down HIV Spread in Cell Cultures.

Published in:

ChemBioChem, 2007, v. 8, n. 15, p. 1850, doi. 10.1002/cbic.200700232

By:

Ludwig, Verena;
Krebs, Andreas;
Stoll, Michaela;
Dietrich, Ursula;
Ferner, Jan;
Schwalbe, Harald;
Scheffer, Ute;
Dürner, Gerd;
Göbel, Michael W.

Publication type:

Article

Targeting the HIV Trans-Activation Responsive RegionApproaches Towards RNA-Binding Drugs.

Published in:

ChemBioChem, 2003, v. 4, n. 10, p. 972, doi. 10.1002/cbic.200300652

By:

Andreas Krebs;
Verena Ludwig;
Oliver Boden;
Michael W. Göbel

Publication type:

Article

Chemical nucleases are a robust alternative for RNase H cleavage of human ribosomal RNA.

Published in:

PLoS ONE, 2025, v. 20, n. 2, p. 1, doi. 10.1371/journal.pone.0318697

By:

Wesseling, Hagen;
Krug, Dennis;
Wehrheim, Marvin;
Göbel, Michael W.;
Kaiser, Stefanie

Publication type:

Article

A Trisbenzimidazole Phosphoramidite Building Block Enables High-Yielding Syntheses of RNA-Cleaving Oligonucleotide Conjugates.

Published in:

Molecules, 2020, v. 25, n. 8, p. 1842, doi. 10.3390/molecules25081842

By:

Zellmann, Felix;
Göbel, Michael W.;
Lönnberg, Harri;
Strömberg, Roger

Publication type:

Article

Site-Specific Cleavage of RNAs Derived from the PIM1 3′-UTR by a Metal-Free Artificial Ribonuclease.

Published in:

Molecules, 2019, v. 24, n. 4, p. 807, doi. 10.3390/molecules24040807

By:

Zellmann, Felix;
Thomas, Laura;
Scheffer, Ute;
Hartmann, Roland K.;
Göbel, Michael W.;
Strömberg, Roger

Publication type:

Article

Nonenzymatic Oligomerization of Ribonucleotides on Guanosine-Rich Templates: Suppression of the Self-Pairing of Guanosine.

Published in:

Angewandte Chemie International Edition, 1997, v. 36, n. 8, p. 842, doi. 10.1002/anie.199708421

By:

Kurz, Markus;
Göbel, Karin;
Hartel, Christian;
Göbel, Michael W.

Publication type:

Article

Bis(guanidinium) Alcohols as Models of Staphylococcal Nuclease: Substrate Binding through Ion Pair Complexes and Fast Phosphoryl Transfer Reactions.

Published in:

Angewandte Chemie International Edition, 1996, v. 35, n. 18, p. 2126, doi. 10.1002/anie.199621261

By:

Muche, Marc-Steffen;
Göbel, Michael W.

Publication type:

Article

Binuclear Metal Complexes as Efficient Intermediaries in Biochemically Relevant Hydrolysis Reactions.

Published in:

Angewandte Chemie International Edition, 1994, v. 33, n. 11, p. 1141, doi. 10.1002/anie.199411411

By:

Göbel, Michael W.

Publication type:

Article

Axially Chiral Amidinium Ions with a Biaryl Skeleton: A New Class of Structure in Host-Guest Chemistry.

Published in:

Angewandte Chemie International Edition, 1994, v. 33, n. 9, p. 984, doi. 10.1002/anie.199409841

By:

Lehr, Stefan;
Schütz, Karin;
Bauch, Markus;
Göbel, Michael W.

Publication type:

Article

En Route to Synthetic Phosphodiesterases: Supramolecular Phosphoryl-Transfer Mediated by Amidinium-Phosphate Contact Ion-Pairs.

Published in:

Angewandte Chemie International Edition, 1992, v. 31, n. 2, p. 207, doi. 10.1002/anie.199202071

By:

Göbel, Michael W.;
Bats, Jan W.;
Dürner, Gerd

Publication type:

Article

The concept of template-based de novo design from drug-derived molecular fragments and its application to TAR RNA.

Published in:

Journal of Computer-Aided Molecular Design, 2008, v. 22, n. 2, p. 59, doi. 10.1007/s10822-007-9157-4

By:

Schüller, Andreas;
Suhartono, Marcel;
Fechner, Uli;
Tanrikulu, Yusuf;
Breitung, Sven;
Scheffer, Ute;
Göbel, Michael W.;
Schneider, Gisbert

Publication type:

Article

Quality Control of mRNA Vaccines by Synthetic Ribonucleases: Analysis of the Poly‐A‐Tail.

Published in:

ChemBioChem, 2024, v. 25, n. 13, p. 1, doi. 10.1002/cbic.202400347

By:

Zellmann, Felix;
Schmauk, Nina;
Murmann, Nina;
Böhm, Madeleine;
Schwenger, Alexander;
Göbel, Michael W.

Publication type:

Article

A Bis(guanidinium)alcohol Attached to a Hairpin Polyamide: Synthesis, DNA Binding, and Plasmid Cleavage.

Published in:

ChemBioChem, 2016, v. 17, n. 6, p. 506, doi. 10.1002/cbic.201500566

By:

Wirth‐Hamdoune, Daniela;
Ullrich, Stefan;
Scheffer, Ute;
Radanović, Toni;
Dürner, Gerd;
Göbel, Michael W.

Publication type:

Article

Cleavage of Phosphodiesters and of DNA by a Bis(guanidinium)naphthol Acting as a Metal-Free Anion Receptor.

Published in:

ChemBioChem, 2011, v. 12, n. 8, p. 1223, doi. 10.1002/cbic.201100022

By:

Ullrich, Stefan;
Nazir, Zarghun;
Büsing, Arne;
Scheffer, Ute;
Wirth, Daniela;
Bats, Jan W.;
Dürner, Gerd;
Göbel, Michael W.

Publication type:

Article

Redirection of the Transcription Factor SP1 to AT Rich Binding Sites by a Synthetic Adaptor Molecule.

Published in:

Helvetica Chimica Acta, 2021, v. 104, n. 9, p. 1, doi. 10.1002/hlca.202100095

By:

Bolz, Mathias;
Scheffer, Ute;
Kalden, Elisabeth;
Göbel, Michael W.

Publication type:

Article

RNA Cleavage Catalyzed by Amphoteric Bis(acyl)guanidinium Derivatives.

Published in:

Helvetica Chimica Acta, 2014, v. 97, n. 2, p. 215, doi. 10.1002/hlca.201300308

By:

Göbel, Michael W.;
Roussev, Christo D.;
Scheffer, Ute

Publication type:

Article

Front Cover: Redirection of miRNA‐Argonaute Complexes to Specific Target Sites by Synthetic Adaptor Molecules (C&B 7/2020).

Published in:

Chemistry & Biodiversity, 2020, v. 17, n. 7, p. 1, doi. 10.1002/cbdv.202000517

By:

Bolz, Mathias;
Thomas, Laura;
Scheffer, Ute;
Kalden, Elisabeth;
Hartmann, Roland K.;
Göbel, Michael W.

Publication type:

Article

Redirection of miRNA‐Argonaute Complexes to Specific Target Sites by Synthetic Adaptor Molecules.

Published in:

Chemistry & Biodiversity, 2020, v. 17, n. 7, p. 1, doi. 10.1002/cbdv.202000272

By:

Bolz, Mathias;
Thomas, Laura;
Scheffer, Ute;
Kalden, Elisabeth;
Hartmann, Roland K.;
Göbel, Michael W.

Publication type:

Article