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Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans.
Published in:
2011
By:
- Haizhong Feng;
- Hu, Bo;
- Kun-Wei Liu;
- Yanxin Li;
- Xinghua Lu;
- Tao Cheng;
- Jia-Jean Yiin;
- Songjian Lu;
- Keezer, Susan;
- Fenton, Tim;
- Furnari, Frank B.;
- Hamilton, Ronald L.;
- Vuori, Kristiina;
- Sarkaria, Jann N.;
- Nagane, Motoo;
- Nishikawa, Ryo;
- Cavenee, Webster K.;
- Shi-Yuan Cheng;
- Feng, Haizhong;
- Liu, Kun-Wei
Publication type:
journal article
Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma.
Published in:
2011
By:
- Staquicini, Fernanda I.;
- Ozawa, Michael G.;
- Moya, Catherine A.;
- Driessen, Wouter H. P.;
- Barbu, E. Magda;
- Nishimori, Hiroyuki;
- Soghomonyan, Suren;
- Flores 2nd, Leo G.;
- Xiaowen Liang;
- Paolillo, Vincenzo;
- Alauddin, Mian M.;
- Basilion, James P.;
- Furnari, Frank B.;
- Bogler, Oliver;
- Lang, Frederick F.;
- Aldape, Kenneth D.;
- Fuller, Gregory N.;
- Höök, Magnus;
- Gelovani, Jun G.;
- Sidman, Richard L.
Publication type:
journal article
A Unified Nomenclature and Amino Acid Numbering for Human PTEN.
Published in:
Science Signaling, 2014, v. 7, n. 332, p. 1, doi. 10.1126/scisignal.2005560
By:
- Pulido, Rafael;
- Baker, Suzanne J.;
- Barata, Joao T.;
- Carracedo, Arkaitz;
- Cid, Victor J.;
- Chin-Sang, Ian D.;
- Davé, Vrushank;
- den Hertog, Jeroen;
- Devreotes, Peter;
- Eickholt, Britta J.;
- Eng, Charis;
- Furnari, Frank B.;
- Georgescu, Maria-Magdalena;
- Gericke, Arne;
- Hopkins, Benjamin;
- Xeujun Jiang;
- Seung-Rock Lee;
- Lösche, Mathias;
- Malaney, Prerna;
- Matias-Guiu, Xavier
Publication type:
Article
Integration of Computational Pipeline to Streamline Efficacious Drug Nomination and Biomarker Discovery in Glioblastoma.
Published in:
Cancers, 2024, v. 16, n. 9, p. 1723, doi. 10.3390/cancers16091723
By:
- Maeser, Danielle;
- Gruener, Robert F.;
- Galvin, Robert;
- Lee, Adam;
- Koga, Tomoyuki;
- Grigore, Florina-Nicoleta;
- Suzuki, Yuta;
- Furnari, Frank B.;
- Chen, Clark;
- Huang, R. Stephanie
Publication type:
Article
Molecular Biology of Malignant Degeneration of Astrocytoma.
Published in:
Pediatric Neurosurgery, 1996, v. 24, n. 1, p. 41, doi. 10.1159/000121013
By:
- Furnari, Frank B.;
- Huang, Su;
- Cavenee, Webster K.
Publication type:
Article
Predictive data-driven modeling of C-terminal tyrosine function in the EGFR signaling network.
Published in:
Life Science Alliance, 2023, v. 6, n. 8, p. 1, doi. 10.26508/lsa.202201466
By:
- Gerritsen, Jacqueline S.;
- Faraguna, Joseph S.;
- Bonavia, Rudy;
- Furnari, Frank B.;
- White, Forest M.
Publication type:
Article
A Key Pathway to Cancer Resilience: The Role of Autophagy in Glioblastomas.
Published in:
Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.652133
By:
- Jandrey, Elisa Helena Farias;
- Bezerra, Marcelle;
- Inoue, Lilian Tiemi;
- Furnari, Frank B.;
- Camargo, Anamaria Aranha;
- Costa, Érico Tosoni
Publication type:
Article
IGF-I receptor signaling in a prostatic cancer cell line with a PTEN mutation.
Published in:
Oncogene, 2000, v. 19, n. 22, p. 2687, doi. 10.1038/sj.onc.1203587
By:
- Reiss, Krzysztof;
- Wang, Jin-Ying;
- Romano, Gaetano;
- Furnari, Frank B;
- Cavenee, Webster K;
- Morrione, Andrea;
- Tu, Xiao;
- Baserga, Renato
Publication type:
Article
PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis.
Published in:
Oncogene, 1999, v. 18, n. 27, p. 3936, doi. 10.1038/sj.onc.1202774
By:
- Wick, Wolfgang;
- Furnari, Frank B;
- Naumann, Ulrike;
- Cavenee, Webster K;
- Weller, Michael
Publication type:
Article
Mapping of genomic EGFRvIII deletions in glioblastoma: insight into rearrangement mechanisms and biomarker development.
Published in:
Neuro-Oncology, 2018, v. 20, n. 10, p. 1310, doi. 10.1093/neuonc/noy058
By:
- Koga, Tomoyuki;
- Li, Bin;
- Figueroa, Javier M;
- Ren, Bing;
- Chen, Clark C;
- Carter, Bob S;
- Furnari, Frank B
Publication type:
Article
EGFR PHOSPHORYLATION OF DCBLD2 RECRUITS TRAF6 AND STIMULATES AKT-PROMOTED TUMORIGENESIS.
Published in:
Neuro-Oncology, 2014, v. 16, n. suppl_3, p. iii16, doi. 10.1093/neuonc/nou206.60
By:
- Cheng, Shiyuan;
- Feng, Haizhong;
- Lopez, Giselle Y.;
- Kim, Chung Kwon;
- Duncan, Christopher G.;
- Alvarez, Angel;
- Nishikawa, Ryo;
- Nagane, Motoo;
- Su, An-Jey;
- Auron, Phillip E.;
- Hedberg, Matthew L.;
- Wang, Lin;
- Grandis, Jennifer R.;
- McLendon, Roger E.;
- Bigner, Darell D.;
- Nakano, Ichiro;
- Joshi, Kaushal;
- Kim, Sunghak;
- Lin, Hui-Kuan;
- Furnari, Frank B.
Publication type:
Article
Report from the Fifth National Cancer Institute Mouse Models of Human Cancers Consortium Nervous System Tumors Workshop.
Published in:
Neuro-Oncology, 2011, v. 13, n. 7, p. 692, doi. 10.1093/neuonc/nor080
By:
- Gutmann, David H.;
- Stiles, Charles D.;
- Lowe, Scott W.;
- Bollag, Gideon E.;
- Furnari, Frank B.;
- Charest, Al
Publication type:
Article
A tale of two approaches: complementary mechanisms of cytotoxic and targeted therapy resistance may inform next-generation cancer treatments.
Published in:
Carcinogenesis, 2013, v. 34, n. 4, p. 725, doi. 10.1093/carcin/bgt086
By:
- Masui, Kenta;
- Gini, Beatrice;
- Wykosky, Jill;
- Zanca, Ciro;
- Mischel, Paul S.;
- Furnari, Frank B.;
- Cavenee, Webster K.
Publication type:
Article
PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3.
Published in:
Nature Communications, 2017, v. 8, n. 5, p. 15223, doi. 10.1038/ncomms15223
By:
- Benitez, Jorge A.;
- Ma, Jianhui;
- D'Antonio, Matteo;
- Boyer, Antonia;
- Camargo, Maria Fernanda;
- Zanca, Ciro;
- Kelly, Stephen;
- Khodadadi-Jamayran, Alireza;
- Jameson, Nathan M.;
- Andersen, Michael;
- Miletic, Hrvoje;
- Saberi, Shahram;
- Frazer, Kelly A.;
- Cavenee, Webster K.;
- Furnari, Frank B.
Publication type:
Article
A novel program of infiltrative control in astrocytomas: ADAM23 depletion promotes cell invasion by activating γ-secretase complex.
Published in:
Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad147
By:
- Jandrey, Elisa Helena Farias;
- Barnabé, Gabriela Filoso;
- Maldaun, Marcos;
- Asprino, Paula Fontes;
- Santos, Natália Cristina dos;
- Inoue, Lilian Tiemi;
- Rozanski, Andrei;
- Galante, Pedro Alexandre Favoretto;
- Marie, Suely Kazue Nagahashi;
- Oba-Shinjo, Sueli Mieko;
- Santos, Tiago Góss dos;
- Chammas, Roger;
- Lancellotti, Carmen Lucia Penteado;
- Furnari, Frank B;
- Camargo, Anamaria Aranha;
- Costa, Érico Tosoni
Publication type:
Article
Combined inhibition of topoisomerase I and poly(ADP-ribose) polymerase: A synergistic therapeutic strategy for glioblastoma with phosphatase and tensin homolog deficiency.
Published in:
Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad102
By:
- Kim, Olga;
- Butler, Madison;
- Sergi, Zach;
- Robey, Robert W;
- Zhang, Meili;
- Chari, Raj;
- Pang, Ying;
- Yu, Guangyang;
- Zhang, Wei;
- Song, Hua;
- Davis, Dionne;
- Hawley, Robert G;
- Wen, Xinyu;
- Wang, Herui;
- Quezado, Martha;
- Tran, Bao;
- Merchant, Mythili;
- Ranjan, Alice;
- Furnari, Frank B;
- Khan, Javed
Publication type:
Article
Nuclear EGFRvIII-STAT5b complex contributes to glioblastoma cell survival by direct activation of the Bcl-XL promoter.
Published in:
International Journal of Cancer, 2013, v. 132, n. 3, p. 509, doi. 10.1002/ijc.27690
By:
- Latha, Khatri;
- Li, Ming;
- Chumbalkar, Vaibhav;
- Gururaj, Anupama;
- Hwang, YeoHyeon;
- DakENg, Sumana;
- Sawaya, Raymond;
- Aldape, KENneth;
- CavENee, Webster K.;
- Bogler, Oliver;
- Furnari, Frank B.
Publication type:
Article
A Kinome-Wide RNAi Screen in Drosophila Glia Reveals That the RIO Kinases Mediate Cell Proliferation and Survival through TORC2-Akt Signaling in Glioblastoma.
Published in:
PLoS Genetics, 2013, v. 9, n. 2, p. 1, doi. 10.1371/journal.pgen.1003253
By:
- Read, Renee D.;
- Fenton, Tim R.;
- Gomez, German G.;
- Wykosky, Jill;
- Vandenberg, Scott R.;
- Babic, Ivan;
- Iwanami, Akio;
- Huijun Yang;
- Cavenee, Webster K.;
- Mischel, Paul S.;
- Furnari, Frank B.;
- Thomas, John B.
Publication type:
Article
A Drosophila Model for EGFR-Ras and PI3K-Dependent Human Glioma.
Published in:
PLoS Genetics, 2009, v. 5, n. 2, p. 1, doi. 10.1371/journal.pgen.1000374
By:
- Read, Renee D.;
- Cavenee, Webster K.;
- Furnari, Frank B.;
- Thomas, John B.
Publication type:
Article
Corrigendum to: EGFR, the Lazarus target for precision oncology in glioblastoma.
Published in:
2023
By:
- Lin, Benjamin;
- Ziebro, Julia;
- Smithberger, Erin;
- Skinner, Kasey R;
- Zhao, Eva;
- Cloughesy, Timothy F;
- Binder, Zev A;
- O'Rourke, Donald M;
- Nathanson, David A;
- Furnari, Frank B;
- Miller, C Ryan
Publication type:
Correction Notice
EGFR, the Lazarus target for precision oncology in glioblastoma.
Published in:
Neuro-Oncology, 2022, v. 24, n. 12, p. 2035, doi. 10.1093/neuonc/noac204
By:
- Lin, Benjamin;
- Ziebro, Julia;
- Smithberger, Erin;
- Skinner, Kasey R;
- Zhao, Eva;
- Cloughesy, Timothy F;
- Binder, Zev A;
- O'Rourke, Donald M;
- Nathanson, David A;
- Furnari, Frank B;
- Miller, C Ryan
Publication type:
Article
Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma.
Published in:
Nature Reviews Cancer, 2015, v. 15, n. 5, p. 302, doi. 10.1038/nrc3918
By:
- Furnari, Frank B.;
- Cloughesy, Timothy F.;
- Cavenee, Webster K.;
- Mischel, Paul S.
Publication type:
Article
Gα12 signaling regulates transcriptional and phenotypic responses that promote glioblastoma tumor invasion.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-49164-4
By:
- Chaim, Olga Meiri;
- Miki, Shunichiro;
- Prager, Briana C.;
- Ma, Jianhui;
- Jeong, Anthony Y.;
- Lara, Jacqueline;
- Tran, Nancy K.;
- Smith, Jeffrey M.;
- Rich, Jeremy N.;
- Gutkind, J. Silvio;
- Miyamoto, Shigeki;
- Furnari, Frank B.;
- Brown, Joan Heller
Publication type:
Article

Found: 23