Works by Funakoshi-Tago, Megumi

Results: 33

Coffee induces vascular endothelial growth factor (VEGF) expression in human neuroblastama SH-SY5Y cells.

Published in:

Nutritional Neuroscience, 2017, v. 20, n. 6, p. 336, doi. 10.1080/1028415X.2015.1133106

By:

Kakio, Shota;
Funakoshi-Tago, Megumi;
Kobata, Kenji;
Tamura, Hiroomi

Publication type:

Article

Pyrrolidinium-type fullerene derivative-induced apoptosis by the generation of reactive oxygen species in HL-60 cells.

Published in:

Free Radical Research, 2009, v. 43, n. 12, p. 1240, doi. 10.3109/10715760903273849

By:

Nishizawa, Chiho;
Hashimoto, Noriyuki;
Yokoo, Sachiko;
Funakoshi-Tago, Megumi;
Kasahara, Tadashi;
Takahashi, Kyoko;
Nakamura, Shigeo;
Mashino, Tadahiko

Publication type:

Article

EBP2, a novel NPM‐ALK‐interacting protein in the nucleolus, contributes to the proliferation of ALCL cells by regulating tumor suppressor p53.

Published in:

Molecular Oncology, 2021, v. 15, n. 1, p. 167, doi. 10.1002/1878-0261.12822

By:

Uchihara, Yuki;
Tago, Kenji;
Tamura, Hiroomi;
Funakoshi‐Tago, Megumi

Publication type:

Article

Oncogenic Ras mutant causes the hyperactivation of NF‐κB via acceleration of its transcriptional activation.

Published in:

Molecular Oncology, 2019, v. 13, n. 11, p. 2493, doi. 10.1002/1878-0261.12580

By:

Tago, Kenji;
Funakoshi‐Tago, Megumi;
Ohta, Satoshi;
Kawata, Hirotoshi;
Saitoh, Hiroshi;
Horie, Hisanaga;
Aoki‐Ohmura, Chihiro;
Yamauchi, Junji;
Tanaka, Akira;
Matsugi, Jitsuhiro;
Yanagisawa, Ken

Publication type:

Article

Roasted Coffee Reduces β‐Amyloid Production by Increasing Proteasomal β‐Secretase Degradation in Human Neuroblastoma SH‐SY5Y Cells.

Published in:

Molecular Nutrition & Food Research, 2018, v. 62, n. 21, p. N.PAG, doi. 10.1002/mnfr.201800238

By:

Fukuyama, Kazuya;
Kakio, Shota;
Nakazawa, Yosuke;
Kobata, Kenji;
Funakoshi‐Tago, Megumi;
Suzuki, Toshiharu;
Tamura, Hiroomi

Publication type:

Article

Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2.

Published in:

EMBO Journal, 2006, v. 25, n. 20, p. 4763, doi. 10.1038/sj.emboj.7601365

By:

Funakoshi-Tago, Megumi;
Pelletier, Stephane;
Matsuda, Tadashi;
Parganas, Evan;
Ihle, James N.

Publication type:

Article

Chemoenzymatic synthesis of hydroxytyrosol monoesters and their suppression effect on nitric oxide production stimulated by lipopolysaccharides.

Published in:

Bioscience, Biotechnology & Biochemistry, 2019, v. 83, n. 2, p. 185, doi. 10.1080/09168451.2018.1530970

By:

Sakakura, Ayaka;
Pauze, Martin;
Namiki, Atsuhiro;
Funakoshi-Tago, Megumi;
Tamura, Hiroomi;
Hanaya, Kengo;
Higashibayashi, Shuhei;
Sugai, Takeshi

Publication type:

Article

Coffee decoction enhances tamoxifen proapoptotic activity on MCF-7 cells.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-76445-z

By:

Funakoshi-Tago, Megumi;
Tago, Kenji;
Li, Chin;
Hokimoto, Shingo;
Tamura, Hiroomi

Publication type:

Article

Identification of DDX5 as an indispensable activator of the glucocorticoid receptor in adipocyte differentiation.

Published in:

FEBS Journal, 2023, v. 290, n. 4, p. 988, doi. 10.1111/febs.16618

By:

Hokimoto, Shingo;
Funakoshi‐Tago, Megumi;
Tago, Kenji

Publication type:

Article

The role of MerTK in promoting cell migration is enhanced by the oncogenic Ras/IL‐33 signaling axis.

Published in:

FEBS Journal, 2022, v. 289, n. 7, p. 1950, doi. 10.1111/febs.16271

By:

Ohta, Satoshi;
Tago, Kenji;
Kuchimaru, Takahiro;
Funakoshi‐Tago, Megumi;
Horie, Hisanaga;
Aoki‐Ohmura, Chihiro;
Matsugi, Jitsuhiro;
Yanagisawa, Ken

Publication type:

Article

STAT3 and ERK pathways are involved in cell growth stimulation of the ST2/ IL1 RL1 promoter.

Published in:

FEBS Open Bio, 2017, v. 7, n. 2, p. 293, doi. 10.1002/2211-5463.12192

By:

Tago, Kenji;
Ohta, Satoshi;
Funakoshi-Tago, Megumi;
Aoki-Ohmura, Chihiro;
Matsugi, Jitsuhiro;
Tominaga, Shin-ichi;
Yanagisawa, Ken

Publication type:

Article

Coffee extract inhibits adipogenesis in 3T3-L1 preadipocyes by interrupting insulin signaling through the downregulation of IRS1.

Published in:

PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0173264

By:

Maki, Chihiro;
Funakoshi-Tago, Megumi;
Aoyagi, Ryohei;
Ueda, Fumihito;
Kimura, Masaki;
Kobata, Kenji;
Tago, Kenji;
Tamura, Hiroomi

Publication type:

Article

Coffee reduces KRAS expression in Caco-2 human colon carcinoma cells via regulation of miRNAs.

Published in:

Oncology Letters, 2017, v. 14, n. 1, p. 1109, doi. 10.3892/ol.2017.6227

By:

TAKUYA NAKAYAMA;
MEGUMI FUNAKOSHI‑TAGO;
HIROOMI TAMURA

Publication type:

Article

Pyrocatechol, a component of coffee, suppresses LPS-induced inflammatory responses by inhibiting NF-κB and activating Nrf2.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-59380-x

By:

Funakoshi-Tago, Megumi;
Nonaka, Yusuke;
Tago, Kenji;
Takeda, Mika;
Ishihara, Yuma;
Sakai, Ami;
Matsutaka, Mari;
Kobata, Kenji;
Tamura, Hiroomi

Publication type:

Article

Alpha-tocopherol attenuates the anti-tumor activity of crizotinib against cells transformed by NPM-ALK.

Published in:

PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0183003

By:

Uchihara, Yuki;
Ueda, Fumihito;
Tago, Kenji;
Nakazawa, Yosuke;
Ohe, Tomoyuki;
Mashino, Tadahiko;
Yokota, Shigenobu;
Kasahara, Tadashi;
Tamura, Hiroomi;
Funakoshi-Tago, Megumi

Publication type:

Article

Functional Role of c-Src in IL-1–Induced NF-κB Activation: c-Src Is a Component of the IKK Complex.

Published in:

Journal of Biochemistry, 2005, v. 137, n. 2, p. 189, doi. 10.1093/jb/mvi018

By:

Funakoshi-Tago, Megumi;
Tago, Kenji;
Andoh, Kumi;
Sonoda, Yoshiko;
Tominaga, Shin-ichi;
Kasahara, Tadashi

Publication type:

Article

K15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-00200-1

By:

Tago, Kenji;
Ohta, Satoshi;
Aoki-Ohmura, Chihiro;
Funakoshi-Tago, Megumi;
Sashikawa, Miho;
Matsui, Takeshi;
Miyamoto, Yuki;
Wada, Taeko;
Oshio, Tomoyuki;
Komine, Mayumi;
Matsugi, Jitsuhiro;
Furukawa, Yusuke;
Ohtsuki, Mamitaro;
Yamauchi, Junji;
Yanagisawa, Ken

Publication type:

Article

Roasting Enhances the Anti-Cataract Effect of Coffee Beans: Ameliorating Selenite-Induced Cataracts in Rats.

Published in:

Current Eye Research, 2017, v. 42, n. 6, p. 864, doi. 10.1080/02713683.2016.1262877

By:

Ishimori, Nana;
Oguchi, Jun;
Nakazawa, Yosuke;
Kobata, Kenji;
Funakoshi-Tago, Megumi;
Tamura, Hiroomi

Publication type:

Article

The Extracellular C-loop Domain Plays an Important Role in the Cell Adhesion Function of Aquaporin 0.

Published in:

Current Eye Research, 2017, v. 42, n. 4, p. 617, doi. 10.1080/02713683.2016.1217547

By:

Nakazawa, Yosuke;
Oka, Mikako;
Funakoshi-Tago, Megumi;
Tamura, Hiroomi;
Takehana, Makoto

Publication type:

Article

FL118 Is a Potent Therapeutic Agent against Chronic Myeloid Leukemia Resistant to BCR-ABL Inhibitors through Targeting RNA Helicase DDX5.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 7, p. 3693, doi. 10.3390/ijms25073693

By:

Takeda, Kengo;
Ohta, Satoshi;
Nagao, Miu;
Kobayashi, Erika;
Tago, Kenji;
Funakoshi-Tago, Megumi

Publication type:

Article

Suppression of Neuroinflammation by Coffee Component Pyrocatechol via Inhibition of NF-κB in Microglia.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 1, p. 316, doi. 10.3390/ijms25010316

By:

Murata, Taisuke;
Tago, Kenji;
Miyata, Kota;
Moriwaki, Yasuhiro;
Misawa, Hidemi;
Kobata, Kenji;
Nakazawa, Yosuke;
Tamura, Hiroomi;
Funakoshi-Tago, Megumi

Publication type:

Article

Novel Mechanism by a Bis-Pyridinium Fullerene Derivative to Induce Apoptosis by Enhancing the MEK-ERK Pathway in a Reactive Oxygen Species-Independent Manner in BCR-ABL-Positive Chronic Myeloid Leukemia-Derived K562 Cells.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 2, p. 749, doi. 10.3390/ijms23020749

By:

Sumi, Kazuya;
Tago, Kenji;
Nakazawa, Yosuke;
Takahashi, Kyoko;
Ohe, Tomoyuki;
Mashino, Tadahiko;
Funakoshi-Tago, Megumi

Publication type:

Article

Critical Roles of Myc-ODC Axis in the Cellular Transformation Induced by Myeloproliferative Neoplasm-Associated JAK2 V617F Mutant.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0052844

By:

Funakoshi-Tago, Megumi;
Sumi, Kazuya;
Kasahara, Tadashi;
Tago, Kenji

Publication type:

Article

High ambient temperature may induce presbyopia via TRPV1 activation.

Published in:

Medical Molecular Morphology, 2024, v. 57, n. 4, p. 268, doi. 10.1007/s00795-024-00391-2

By:

Nakazawa, Yosuke;
Kuno, Yumika;
Shimada, Hibiki;
Nagai, Noriaki;
Hiramatsu, Noriko;
Takeda, Shun;
Yamamoto, Naoki;
Funakoshi-Tago, Megumi;
Sasaki, Hiroshi

Publication type:

Article

Aquaporins contribute to vacuoles formation in Nile grass type II diabetic rats.

Published in:

Medical Molecular Morphology, 2023, v. 56, n. 4, p. 274, doi. 10.1007/s00795-023-00365-w

By:

Aihara, Kana;
Nakazawa, Yosuke;
Takeda, Shun;
Hatsusaka, Natsuko;
Onouchi, Takanori;
Hiramatsu, Noriko;
Nagata, Mayumi;
Nagai, Noriaki;
Funakoshi-Tago, Megumi;
Yamamoto, Naoki;
Sasaki, Hiroshi

Publication type:

Article

Effect of Alpha-Glucosyl-Hesperidin Consumption on Lens Sclerosis and Presbyopia.

Published in:

Cells (2073-4409), 2021, v. 10, n. 2, p. 382, doi. 10.3390/cells10020382

By:

Nakazawa, Yosuke;
Doki, Yuri;
Sugiyama, Yuki;
Kobayashi, Ryota;
Nagai, Noriaki;
Morisita, Naoki;
Endo, Shin;
Funakoshi-Tago, Megumi;
Tamura, Hiroomi;
Kubo, Eri

Publication type:

Article

Hesperetin treatment attenuates glycation of lens proteins and advanced‑glycation end products generation.

Published in:

Molecular Medicine Reports, 2023, v. 27, n. 5, p. N.PAG, doi. 10.3892/mmr.2023.12990

By:

Doki, Yuri;
Nakazawa, Yosuke;
Morishita, Naoki;
Endo, Shin;
Nagai, Noriaki;
Yamamoto, Naoki;
Tamura, Hiroomi;
Funakoshi-Tago, Megumi

Publication type:

Article

Effect of hesperetin derivatives on the development of selenite-induced cataracts in rats.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 1, p. 1043, doi. 10.3892/mmr.2018.9045

By:

Nakazawa, Yosuke;
Pauze, Martin;
Fukuyama, Kazuya;
Nagai, Noriaki;
Funakoshi-Tago, Megumi;
Sugai, Takeshi;
Tamura, Hiroomi

Publication type:

Article

Aurora kinase A critically contributes to the resistance to anti-cancer drug cisplatin in JAK2 V617F mutant-induced transformed cells

Published in:

FEBS Letters, 2011, v. 585, n. 12, p. 1884, doi. 10.1016/j.febslet.2011.04.068

By:

Sumi, Kazuya;
Tago, Kenji;
Kasahara, Tadashi;
Funakoshi-Tago, Megumi

Publication type:

Article

Jak2 FERM Domain Interaction with the Erythropoietin Receptor Regulates Jak2 Kinase Activity.

Published in:

Molecular & Cellular Biology, 2008, v. 28, n. 5, p. 31, doi. 10.1128/MCB.01447-07

By:

Funakoshi-Tago, Megumi;
Pelletier, Stéphane;
Moritake, Hiroshi;
Parganas, Evan;
Ihle, James N.

Publication type:

Article

Two Domains of the Erythropoietin Receptor Are Sufficient for Jak2 Binding/Activation and Function.

Published in:

Molecular & Cellular Biology, 2006, v. 26, n. 22, p. 27, doi. 10.1128/MCB.01035-06

By:

Pelletier, Stéphane;
Gingras, Sébastien;
Funakoshi-Tago, Megumi;
Howell, Sherié;
Ihle, James N.

Publication type:

Article

Coffee brew intake can prevent the reduction of lens glutathione and ascorbic acid levels in HFD-fed animals.

Published in:

Experimental & Therapeutic Medicine, 2019, v. 17, n. 2, p. 1420

By:

Nakazawa, Yosuke;
Ishimori, Nana;
Oguchi, Jun;
Nagai, Noriaki;
Kimura, Masaki;
Funakoshi-Tago, Megumi;
Tamura, Hiroomi

Publication type:

Article

A mouse model reveals that Mfsd2a is critical for unfolded protein response upon exposure to tunicamycin.

Published in:

Human Cell, 2017, v. 30, n. 2, p. 88, doi. 10.1007/s13577-016-0153-7

By:

Moritake, Hiroshi;
Obara, Megumi;
Saito, Yusuke;
Kashimada, Ayako;
Takagi, Masatoshi;
Funakoshi-Tago, Megumi;
Fukuyama, Tomofusa;
Yoshioka, Mikio;
Inoue, Akira;
Komatsu, Hiroyuki;
Nishitoh, Hideki;
Kataoka, Hiroaki;
Nunoi, Hiroyuki

Publication type:

Article