Works by Funaki, Yoshihito

Results: 30

Cholinergic Deficit and Response to Donepezil Therapy in Parkinson's Disease with Dementia.

Published in:

European Neurology, 2012, v. 68, n. 3, p. 137, doi. 10.1159/000338774

By:

Hiraoka, Kotaro;
Okamura, Nobuyuki;
Funaki, Yoshihito;
Hayashi, Akiko;
Tashiro, Manabu;
Hisanaga, Kinya;
Fujii, Toshikatsu;
Takeda, Atsushi;
Yanai, Kazuhiko;
Iwata, Ren;
Mori, Etsuro

Publication type:

Article

Correlations of 18F-THK5351 PET with Postmortem Burden of Tau and Astrogliosis in Alzheimer Disease.

Published in:

Journal of Nuclear Medicine, 2018, v. 59, n. 4, p. 671, doi. 10.2967/jnumed.117.197426

By:

Ryuichi Harada;
Aiko Ishiki;
Hideaki Kai;
Naomi Sato;
Katsutoshi Furukawa;
Shozo Furumoto;
Tetsuro Tago;
Naoki Tomita;
Shoichi Watanuki;
Kotaro Hiraoka;
Yoichi Ishikawa;
Yoshihito Funaki;
Tadaho Nakamura;
Takeo Yoshikawa;
Ren Iwata;
Manabu Tashiro;
Hironobu Sasano;
Tetsuyuki Kitamoto;
Kazuhiko Yanai;
Hiroyuki Arai

Publication type:

Article

18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease.

Published in:

Journal of Nuclear Medicine, 2016, v. 57, n. 2, p. 208, doi. 10.2967/jnumed.115.164848

By:

Ryuichi Harada;
Nobuyuki Okamura;
Shozo Furumoto;
Katsutoshi Furukawa;
Aiko Ishiki;
Naoki Tomita;
Tetsuro Tago;
Kotaro Hiraoka;
Shoichi Watanuki;
Miho Shidahara;
Masayasu Miyake;
Yoichi Ishikawa;
Rin Matsuda;
Akie Inami;
Takeo Yoshikawa;
Yoshihito Funaki;
Ren Iwata;
Manabu Tashiro;
Kazuhiko Yanai;
Hiroyuki Arai

Publication type:

Article

Delivery of Na/I Symporter Gene into Skeletal Muscle Using Nanobubbles and Ultrasound: Visualization of Gene Expression by PET.

Published in:

Journal of Nuclear Medicine, 2010, v. 51, n. 6, p. 951, doi. 10.2967/jnumed.109.074443

By:

Watanabe, Yukiko;
Horie, Sachiko;
Funaki, Yoshihito;
Kikuchi, Youhei;
Yamazaki, Hiromichi;
Ishii, Keizo;
Mori, Shiro;
Vassaux, Georges;
Kodama, Tetsuya

Publication type:

Article

Dose dependency of brain histamine H1 receptor occupancy following oral administration of cetirizine hydrochloride measured using PET with [11C]doxepin.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2009, v. 24, n. 7, p. 540, doi. 10.1002/hup.1051

By:

Tashiro, Manabu;
Kato, Motohisa;
Miyake, Masayasu;
Watanuki, Shoichi;
Funaki, Yoshihito;
Ishikawa, Yoichi;
Iwata, Ren;
Yanai, Kazuhiko

Publication type:

Article

Binding and safety profile of novel benzoxazole derivative for in vivo imaging of amyloid deposits in Alzheimer's disease.

Published in:

Geriatrics & Gerontology International, 2007, v. 7, n. 4, p. 393, doi. 10.1111/j.1447-0594.2007.00430.x

By:

Okamura, Nobuyuki;
Furumoto, Shozo;
Funaki, Yoshihito;
Suemoto, Takahiro;
Kato, Motohisa;
Ishikawa, Yoichi;
Ito, Satoshi;
Akatsu, Hiroyasu;
Yamamoto, Takayuki;
Sawada, Tohru;
Arai, Hiroyuki;
Kudo, Yukitsuka;
Yanai, Kazuhiko

Publication type:

Article

Brain histamine H1 receptor occupancy after oral administration of desloratadine and loratadine.

Published in:

Pharmacology Research & Perspectives, 2019, v. 7, n. 4, p. N.PAG, doi. 10.1002/prp2.499

By:

Nakamura, Tadaho;
Hiraoka, Kotaro;
Harada, Ryuichi;
Matsuzawa, Takuro;
Ishikawa, Yoichi;
Funaki, Yoshihito;
Yoshikawa, Takeo;
Tashiro, Manabu;
Yanai, Kazuhiko;
Okamura, Nobuyuki

Publication type:

Article

18F-THK5351 Positron Emission Tomography Imaging in Neurodegenerative Tauopathies.

Published in:

Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.761010

By:

Ezura, Michinori;
Kikuchi, Akio;
Okamura, Nobuyuki;
Ishiki, Aiko;
Hasegawa, Takafumi;
Harada, Ryuichi;
Watanuki, Shoichi;
Funaki, Yoshihito;
Hiraoka, Kotaro;
Baba, Toru;
Sugeno, Naoto;
Yoshida, Shun;
Kobayashi, Junpei;
Kobayashi, Michiko;
Tano, Ohito;
Ishiyama, Shun;
Nakamura, Takaaki;
Nakashima, Ichiro;
Mugikura, Shunji;
Iwata, Ren

Publication type:

Article

[F]THK-5117 PET for assessing neurofibrillary pathology in Alzheimer's disease.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2015, v. 42, n. 7, p. 1052, doi. 10.1007/s00259-015-3035-4

By:

Harada, Ryuichi;
Okamura, Nobuyuki;
Furumoto, Shozo;
Furukawa, Katsutoshi;
Ishiki, Aiko;
Tomita, Naoki;
Hiraoka, Kotaro;
Watanuki, Shoichi;
Shidahara, Miho;
Miyake, Masayasu;
Ishikawa, Yoichi;
Matsuda, Rin;
Inami, Akie;
Yoshikawa, Takeo;
Tago, Tetsuro;
Funaki, Yoshihito;
Iwata, Ren;
Tashiro, Manabu;
Yanai, Kazuhiko;
Arai, Hiroyuki

Publication type:

Article

Neuroimaging-pathological correlations of [18F]THK5351 PET in progressive supranuclear palsy.

Published in:

Acta Neuropathologica Communications, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40478-018-0556-7

By:

Ishiki, Aiko;
Harada, Ryuichi;
Kai, Hideaki;
Sato, Naomi;
Totsune, Tomoko;
Tomita, Naoki;
Watanuki, Shoichi;
Hiraoka, Kotaro;
Ishikawa, Yoichi;
Funaki, Yoshihito;
Iwata, Ren;
Furumoto, Shozo;
Tashiro, Manabu;
Sasano, Hironobu;
Kitamoto, Tetsuyuki;
Kudo, Yukitsuka;
Yanai, Kazuhiko;
Furukawa, Katsutoshi;
Okamura, Nobuyuki;
Arai, Hiroyuki

Publication type:

Article

[11C]Doxepin binding to histamine H1 receptors in living human brain: Reproducibility during attentive waking and circadian rhythm.

Published in:

Frontiers in Systems Neuroscience, 2012, p. 1, doi. 10.3389/fnsys.2012.00045

By:

Shibuya, Katsuhiko;
Funaki, Yoshihito;
Hiraoka, Kotaro;
Yoshikawa, Takeo;
Naganuma, Fumito;
Miyake, Masayasu;
Watanuki, Shoichi;
Sato, Hirotoshi;
Tashiro, Manabu;
Yanai, Kazuhiko

Publication type:

Article

Histamine H receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers.

Published in:

Psychopharmacology, 2015, v. 232, n. 19, p. 3497, doi. 10.1007/s00213-015-4002-2

By:

Sato, Hirotoshi;
Ito, Chihiro;
Hiraoka, Kotaro;
Tashiro, Manabu;
Shibuya, Katsuhiko;
Funaki, Yoshihito;
Yoshikawa, Takeo;
Iwata, Ren;
Matsuoka, Hiroo;
Yanai, Kazuhiko

Publication type:

Article

Histamine H receptor occupancy by the new-generation antidepressants fluvoxamine and mirtazapine: a positron emission tomography study in healthy volunteers.

Published in:

Psychopharmacology, 2013, v. 230, n. 2, p. 227, doi. 10.1007/s00213-013-3146-1

By:

Sato, Hirotoshi;
Ito, Chihiro;
Tashiro, Manabu;
Hiraoka, Kotaro;
Shibuya, Katsuhiko;
Funaki, Yoshihito;
Iwata, Ren;
Matsuoka, Hiroo;
Yanai, Kazuhiko

Publication type:

Article

Decreased striatal D2 receptor density associated with severe behavioral abnormality in Alzheimer's disease.

Published in:

Annals of Nuclear Medicine, 2003, v. 17, n. 7, p. 567, doi. 10.1007/BF03006670

By:

Tanaka, Yasuhiro;
Meguro, Kenichi;
Yamaguchi, Satoshi;
Ishii, Hiroshi;
Watanuki, Shoichi;
Funaki, Yoshihito;
Yamaguchi, Keiichiro;
Yamadori, Atsushi;
Iwata, Ren;
Itoh, Masatoshi

Publication type:

Article

Decreased striatal D2 receptor density associated with severe behavioral abnormality in Alzheimer’s disease.

Published in:

Annals of Nuclear Medicine, 2002, v. 17, n. 7, p. 567, doi. 10.1007/BF03006670

By:

Tanaka, Yasuhiro;
Meguro, Kenichi;
Yamaguchi, Satoshi;
Ishii, Hiroshi;
Watanuki, Shoichi;
Funaki, Yoshihito;
Yamaguchi, Keiichiro;
Yamadori, Atsushi;
Iwata, Ren;
Itoh, Masatoshi

Publication type:

Article

In vivo visualization of α-synuclein deposition by carbon-11-labelled 2-[2-(2-dimethylaminothiazol-5-yl)ethenyl]-6-[2-(fluoro)ethoxy]benzoxazole positron emission tomography in multiple system atrophy.

Published in:

Brain: A Journal of Neurology, 2010, v. 133, n. 6, p. 1772, doi. 10.1093/brain/awq091

By:

Kikuchi, Akio;
Takeda, Atsushi;
Okamura, Nobuyuki;
Tashiro, Manabu;
Hasegawa, Takafumi;
Furumoto, Shozo;
Kobayashi, Michiko;
Sugeno, Naoto;
Baba, Toru;
Miki, Yasuo;
Mori, Fumiaki;
Wakabayashi, Koichi;
Funaki, Yoshihito;
Iwata, Ren;
Takahashi, Shoki;
Fukuda, Hiroshi;
Arai, Hiroyuki;
Kudo, Yukitsuka;
Yanai, Kazuhiko;
Itoyama, Yasuto

Publication type:

Article

The neuromodulatory role of dopamine in improved reaction time by acute cardiovascular exercise.

Published in:

Journal of Physiology, 2024, v. 602, n. 3, p. 461, doi. 10.1113/JP285173

By:

Ando, Soichi;
Fujimoto, Toshihiko;
Sudo, Mizuki;
Watanuki, Shoichi;
Hiraoka, Kotaro;
Takeda, Kazuko;
Takagi, Yoko;
Kitajima, Daisuke;
Mochizuki, Kodai;
Matsuura, Koki;
Katagiri, Yuki;
Nasir, Fairuz Mohd;
Lin, Yuchen;
Fujibayashi, Mami;
Costello, Joseph T.;
McMorris, Terry;
Ishikawa, Yoichi;
Funaki, Yoshihito;
Furumoto, Shozo;
Watabe, Hiroshi

Publication type:

Article

Non-invasive imaging of radiocesium dynamics in a living animal using a positron-emitting 127Cs tracer.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-73351-2

By:

Suzui, Nobuo;
Shibata, Takuya;
Yin, Yong-Gen;
Funaki, Yoshihito;
Kurita, Keisuke;
Hoshina, Hiroyuki;
Yamaguchi, Mitsutaka;
Fujimaki, Shu;
Seko, Noriaki;
Watabe, Hiroshi;
Kawachi, Naoki

Publication type:

Article

Brain histamine H1 receptor occupancy of orally administered antihistamines, bepotastine and diphenhydramine, measured by PET with 11C-doxepin.

Published in:

British Journal of Clinical Pharmacology, 2008, v. 65, n. 6, p. 811, doi. 10.1111/j.1365-2125.2008.03143.x

By:

Tashiro, Manabu;
Xudong Duan;
Kato, Motohisa;
Miyake, Masayasu;
Watanuki, Shoichi;
Ishikawa, Yoichi;
Funaki, Yoshihito;
Iwata, Ren;
Itoh, Masatoshi;
Yanai, Kazuhiko

Publication type:

Article

In vivo visualization of donepezil binding in the brain of patients with Alzheimer's disease.

Published in:

British Journal of Clinical Pharmacology, 2008, v. 65, n. 4, p. 472, doi. 10.1111/j.1365-2125.2007.03063.x

By:

Okamura, Nobuyuki;
Funaki, Yoshihito;
Tashiro, Manabu;
Kato, Motohisa;
Ishikawa, Yoichi;
Maruyama, Masahiro;
Ishikawa, Hiroyasu;
Meguro, Kenichi;
Iwata, Ren;
Yanai, Kazuhiko

Publication type:

Article

Longitudinal Assessment of Tau Pathology in Patients with Alzheimer’s Disease Using [18F]THK-5117 Positron Emission Tomography.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0140311

By:

Ishiki, Aiko;
Okamura, Nobuyuki;
Furukawa, Katsutoshi;
Furumoto, Shozo;
Harada, Ryuichi;
Tomita, Naoki;
Hiraoka, Kotaro;
Watanuki, Shoichi;
Ishikawa, Yoichi;
Tago, Tetsuro;
Funaki, Yoshihito;
Iwata, Ren;
Tashiro, Manabu;
Yanai, Kazuhiko;
Kudo, Yukitsuka;
Arai, Hiroyuki

Publication type:

Article

Central Effects of Fexofenadine and Cetirizine: Measurement of Psychomotor Performance, Subjective Sleepiness, and Brain Histamine H1-Receptor Occupancy Using 11C-Doxepin Positron Emission Tomography.

Published in:

Journal of Clinical Pharmacology, 2004, v. 44, n. 8, p. 890

By:

Manabu Tashiro;
Yumiko Sakurada;
Kentaro Iwabuchi;
Hideki Mochizuki;
Motohisa Kato;
Mariko Aoki;
Yoshihito Funaki;
Masatoshi Itoh;
Ren Iwata;
Dean F. Wong;
Kazuhiko Yanai

Publication type:

Article

Positron Emission Tomography Study of the Alterations in Brain Distribution of [11C]Methamphetamine in Methamphetamine-Sensitized Doga.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 801, n. 1, p. 401, doi. 10.1111/j.1749-6632.1996.tb17462.x

By:

NAKAMURA, HITOSHI;
HISHINUMA, TAKANORI;
TOMIOKA, YOSHIHISA;
IDO, TATSUO;
IWATA, REN;
FUNAKI, YOSHIHITO;
ITOH, MASATOSHI;
FUJIWARA, TAKEHIKO;
YANAI, KAZUHIKO;
SATO, MITSUMOTO;
NUMACHI, YOHTARO;
YOSHIDA, SUMIKO;
MIZUGAKI, MICHINAO

Publication type:

Article

Na18F accumulates on the compressive side of peri-implant bone under immediate loading.

Published in:

Odontology, 2018, v. 106, n. 3, p. 232, doi. 10.1007/s10266-017-0327-0

By:

Yamamoto, Miou;
Ogawa, Toru;
Yokoyama, Masayoshi;
Funaki, Yoshihito;
Shobara, Kenta;
Shibamoto, Aya;
Vanegas Sáenz, Juan Ramón;
Sasaki, Keiichi

Publication type:

Article

P2-441: Decreased binding of [11C] donepezil as shown by PET correlated with clinical effect of donepezil administration in Alzheimer's disease: The Osaki-Tajiri project (4)

Published in:

2008

By:

Kasuya, Masashi;
Ishikawa, Hiroyasu;
Okamura, Nobuyuki;
Kato, Motohisa;
Sasaki, Yumi;
Nakata, Eriko;
Ishikawa, Yoichi;
Funaki, Yoshihito;
Tanaka, Naofumi;
Iwata, Ren;
Yanai, Kazuhiko;
Meguro, Kenichi

Publication type:

Abstract

IC-P3-189: Decreased binding of [11C] donepezil as shown by PET correlated with clinical effect of donepezil administration in Alzheimer's disease: The Osaki-Tajiri project (4)

Published in:

2008

By:

Kasuya, Masashi;
Ishikawa, Hiroyasu;
Okamura, Nobuyuki;
Kato, Motohisa;
Sasaki, Yumi;
Nakata, Eriko;
Ishikawa, Yoichi;
Funaki, Yoshihito;
Tanaka, Naofumi;
Iwata, Ren;
Yanai, Kazuhiko;
Meguro, Kenichi

Publication type:

Abstract

P2-320: 18F-labeled ethenyl-benzoxazole derivatives for in vivo detection of amyloid plaques in the brain

Published in:

2006

By:

Okamura, Nobuyuki;
Furumoto, Shozo;
Ito, Satoshi;
Fujikawa, Yousuke;
Tashiro, Manabu;
Funaki, Yoshihito;
Akatsu, Hiroyasu;
Yamamoto, Takayuki;
Iwata, Ren;
Arai, Hiroyuki;
Yanai, Kazuhiko;
Kudo, Yukitsuka

Publication type:

Abstract

P2-320: 18F-labeled ethenyl-benzoxazole derivatives for in vivo detection of amyloid plaques in the brain

Published in:

2006

By:

Okamura, Nobuyuki;
Furumoto, Shozo;
Ito, Satoshi;
Fujikawa, Yousuke;
Tashiro, Manabu;
Funaki, Yoshihito;
Akatsu, Hiroyasu;
Yamamoto, Takayuki;
Iwata, Ren;
Arai, Hiroyuki;
Yanai, Kazuhiko;
Kudo, Yukitsuka

Publication type:

Abstract

Initial evaluation of dynamic human imaging using 18F-FRP170 as a new PET tracer for imaging hypoxia.

Published in:

2007

By:

Kaneta, Tomohiro;
Takai, Yoshihiro;
Iwata, Ren;
Hakamatsuka, Takashi;
Yasuda, Hiroyasu;
Nakayama, Katsutoshi;
Ishikawa, Yoichi;
Watanuki, Shoichi;
Furumoto, Shozo;
Funaki, Yoshihito;
Nakata, Eiko;
Jingu, Keiichi;
Tsujitani, Michihiko;
Ito, Masatoshi;
Fukuda, Hiroshi;
Takahashi, Shoki;
Yamada, Shogo

Publication type:

journal article

Decreased histamine H1 receptor binding in the brain of depressed patients.

Published in:

European Journal of Neuroscience, 2004, v. 20, n. 3, p. 803, doi. 10.1111/j.1460-9568.2004.03540.x

By:

Kano, Michiko;
Fukudo, Shin;
Tashiro, Atshushi;
Utsumi, Atshushi;
Tamura, Daisaku;
Itoh, Masatoshi;
Iwata, Ren;
Tashiro, Manabu;
Mochizuki, Hideki;
Funaki, Yoshihito;
Kato, Motohisa;
Hongo, Michio;
Yanai, Kazuhiko

Publication type:

Article

Works by Funaki, Yoshihito

Cholinergic Deficit and Response to Donepezil Therapy in Parkinson's Disease with Dementia.

Correlations of <sup>18</sup>F-THK5351 PET with Postmortem Burden of Tau and Astrogliosis in Alzheimer Disease.

<sup>18</sup>F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease.

Delivery of Na/I Symporter Gene into Skeletal Muscle Using Nanobubbles and Ultrasound: Visualization of Gene Expression by PET.

Dose dependency of brain histamine H1 receptor occupancy following oral administration of cetirizine hydrochloride measured using PET with [<sup>11</sup>C]doxepin.

Binding and safety profile of novel benzoxazole derivative for in vivo imaging of amyloid deposits in Alzheimer's disease.

Brain histamine H<sub>1</sub> receptor occupancy after oral administration of desloratadine and loratadine.

<sup>18</sup>F-THK5351 Positron Emission Tomography Imaging in Neurodegenerative Tauopathies.

[F]THK-5117 PET for assessing neurofibrillary pathology in Alzheimer's disease.

Neuroimaging-pathological correlations of [<sup>18</sup>F]THK5351 PET in progressive supranuclear palsy.

[<sup>11</sup>C]Doxepin binding to histamine H1 receptors in living human brain: Reproducibility during attentive waking and circadian rhythm.

Histamine H receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers.

Histamine H receptor occupancy by the new-generation antidepressants fluvoxamine and mirtazapine: a positron emission tomography study in healthy volunteers.

Decreased striatal D<sub>2</sub> receptor density associated with severe behavioral abnormality in Alzheimer's disease.

Decreased striatal D<sub>2</sub> receptor density associated with severe behavioral abnormality in Alzheimer’s disease.

In vivo visualization of α-synuclein deposition by carbon-11-labelled 2-[2-(2-dimethylaminothiazol-5-yl)ethenyl]-6-[2-(fluoro)ethoxy]benzoxazole positron emission tomography in multiple system atrophy.

The neuromodulatory role of dopamine in improved reaction time by acute cardiovascular exercise.

Non-invasive imaging of radiocesium dynamics in a living animal using a positron-emitting <sup>127</sup>Cs tracer.

Brain histamine H<sub>1</sub> receptor occupancy of orally administered antihistamines, bepotastine and diphenhydramine, measured by PET with <sup>11</sup>C-doxepin.

In vivo visualization of donepezil binding in the brain of patients with Alzheimer's disease.

Longitudinal Assessment of Tau Pathology in Patients with Alzheimer’s Disease Using [<sup>18</sup>F]THK-5117 Positron Emission Tomography.

Central Effects of Fexofenadine and Cetirizine: Measurement of Psychomotor Performance, Subjective Sleepiness, and Brain Histamine H1-Receptor Occupancy Using 11C-Doxepin Positron Emission Tomography.

Positron Emission Tomography Study of the Alterations in Brain Distribution of [<sup>11</sup>C]Methamphetamine in Methamphetamine-Sensitized Dog<sup>a</sup>.

Na<sup>18</sup>F accumulates on the compressive side of peri-implant bone under immediate loading.

P2-441: Decreased binding of [<sup>11</sup>C] donepezil as shown by PET correlated with clinical effect of donepezil administration in Alzheimer's disease: The Osaki-Tajiri project (4)

IC-P3-189: Decreased binding of [<sup>11</sup>C] donepezil as shown by PET correlated with clinical effect of donepezil administration in Alzheimer's disease: The Osaki-Tajiri project (4)

P2-320: 18F-labeled ethenyl-benzoxazole derivatives for in vivo detection of amyloid plaques in the brain

P2-320: 18F-labeled ethenyl-benzoxazole derivatives for in vivo detection of amyloid plaques in the brain

Initial evaluation of dynamic human imaging using 18F-FRP170 as a new PET tracer for imaging hypoxia.

Decreased histamine H<sub>1</sub> receptor binding in the brain of depressed patients.