Works by Fumikazu Okajima

Results: 29

Extracellular acidification-induced CXCL8 production through a proton-sensing receptor OGR1 in human airway smooth muscle cells: a response inhibited by dexamethasone.

Published in:

Journal of Inflammation, 2019, v. 16, n. 1, p. N.PAG, doi. 10.1186/s12950-019-0207-1

By:

Kadowaki, Maiko;
Yamada, Hidenori;
Sato, Koichi;
Shigemi, Hiroko;
Umeda, Yukihiro;
Morikawa, Miwa;
Waseda, Yuko;
Anzai, Masaki;
Kamide, Yosuke;
Aoki-Saito, Haruka;
Hisada, Takeshi;
Okajima, Fumikazu;
Ishizuka, Tamotsu

Publication type:

Article

Manganese and cobalt activate zebrafish ovarian cancer G-protein-coupled receptor 1 but not GPR4.

Published in:

Journal of Receptors & Signal Transduction, 2017, v. 37, n. 4, p. 401, doi. 10.1080/10799893.2017.1298130

By:

Negishi, Jun;
Omori, Yuka;
Shindo, Mami;
Takanashi, Hayate;
Musha, Shiori;
Nagayama, Suminori;
Hirayama, Jun;
Nishina, Hiroshi;
Nakakura, Takashi;
Mogi, Chihiro;
Sato, Koichi;
Okajima, Fumikazu;
Mochimaru, Yuta;
Tomura, Hideaki

Publication type:

Article

The protective role of proton-sensing TDAG8 in the brain injury in a mouse ischemia reperfusion model.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-74372-7

By:

Sato, Koichi;
Tobo, Ayaka;
Mogi, Chihiro;
Tobo, Masayuki;
Yamane, Nobuhiro;
Tosaka, Masahiko;
Tomura, Hideaki;
Im, Dong-Soon;
Okajima, Fumikazu

Publication type:

Article

LPA1 receptors mediate stimulation, whereas LPA2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites.

Published in:

Carcinogenesis, 2009, v. 30, n. 3, p. 457, doi. 10.1093/carcin/bgp011

By:

Mayumi Komachi;
Hideaki Tomura;
Enkhzol Malchinkhuu;
Masayuki Tobo;
Chihiro Mogi;
Takayuki Yamada;
Takao Kimura;
Atsushi Kuwabara;
Hideo Ohta;
Doon-Soon Im;
Hitoshi Kurose;
Izumi Takeyoshi;
Koichi Sato;
Fumikazu Okajima

Publication type:

Article

Author Correction: Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01594-1

By:

Morizawa, Yosuke M.;
Yuri Hirayama;
Nobuhiko Ohno;
Shinsuke Shibata;
Eiji Shigetomi;
Yang Sui;
Junichi Nabekura;
Koichi Sato;
Fumikazu Okajima;
Hirohide Takebayashi;
Hideyuki Okano;
Schuichi Koizumi

Publication type:

Article

Role of extracellular proton-sensing OGR1 in regulation of insulin secretion and pancreatic β-cell functions.

Published in:

Endocrine Journal, 2014, v. 61, n. 2, p. 101, doi. 10.1507/endocrj.ej13-0380

By:

Chihiro Mogi;
Takashi Nakakura;
Fumikazu Okajima

Publication type:

Article

Growth dependency of a new human pancreatic cancer cell line, YAPC, on autocrine interleukin-1α stimulation.

Published in:

International Journal of Cancer, 1998, v. 76, n. 1, p. 141, doi. 10.1002/(SICI)1097-0215(19980330)76:1<141::AID-IJC22>3.0.CO;2-E

By:

Yamada, Takayuki;
Okajima, Fumikazu;
Adachi, Masakazu;
Ohwada, Susumu;
Kondo, Yoichi

Publication type:

Article

Ionotropic and Metabotropic Proton-Sensing Receptors Involved in Airway Inflammation in Allergic Asthma.

Published in:

Mediators of Inflammation, 2014, v. 2014, p. 1, doi. 10.1155/2014/712962

By:

Haruka Aoki;
Chihiro Mogi;
Fumikazu Okajima

Publication type:

Article

Omega-3 fatty acids induce Ca2+ mobilization responses in human colon epithelial cell lines endogenously expressing FFA4.

Published in:

Acta Pharmacologica Sinica, 2015, v. 36, n. 7, p. 813, doi. 10.1038/aps.2015.29

By:

Kim, Jung-min;
Lee, Kyoung-pil;
Park, Soo-jin;
Kang, Saeromi;
Huang, Jin;
Lee, Jung-min;
Sato, Koichi;
Chung, Hae-young;
Okajima, Fumikazu;
Im, Dong-soon

Publication type:

Article

Increase in sphingolipid catabolic enzyme activity during aging.

Published in:

Acta Pharmacologica Sinica, 2009, v. 30, n. 10, p. 1454, doi. 10.1038/aps.2009.136

By:

Santosh J. SACKET;
Hae-young CHUNG;
Fumikazu OKAJIMA;
Dong-soon IM

Publication type:

Article

17(R)-resolvin D1 ameliorates bleomycin-induced pulmonary fibrosis in mice.

Published in:

Physiological Reports, 2015, v. 3, n. 12, p. n/a, doi. 10.14814/phy2.12628

By:

Yatomi, Masakiyo;
Hisada, Takeshi;
Ishizuka, Tamotsu;
Koga, Yasuhiko;
Ono, Akihiro;
Kamide, Yosuke;
Seki, Kaori;
Aoki‐Saito, Haruka;
Tsurumaki, Hiroaki;
Sunaga, Noriaki;
Kaira, Kyoichi;
Dobashi, Kunio;
Yamada, Masanobu;
Okajima, Fumikazu

Publication type:

Article

Orally active lysophosphatidic acid receptor antagonist attenuates pancreatic cancer invasion and metastasis in vivo.

Published in:

Cancer Science, 2012, v. 103, n. 6, p. 1099, doi. 10.1111/j.1349-7006.2012.02246.x

By:

Komachi, Mayumi;
Sato, Koichi;
Tobo, Masayuki;
Mogi, Chihiro;
Yamada, Takayuki;
Ohta, Hideo;
Tomura, Hideaki;
Kimura, Takao;
Im, Dong-Soon;
Yanagida, Keisuke;
Ishii, Satoshi;
Takeyoshi, Izumi;
Okajima, Fumikazu

Publication type:

Article

Alamandine reduces leptin expression through the c-Src/p38 MAP kinase pathway in adipose tissue.

Published in:

PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0178769

By:

Uchiyama, Tsuyoshi;
Okajima, Fumikazu;
Mogi, Chihiro;
Tobo, Ayaka;
Tomono, Shoichi;
Sato, Koichi

Publication type:

Article

Analysis of vasopressin-induced Ca2+ increase in rat hepatocytes.

Published in:

Archives of Pharmacal Research, 2003, v. 26, n. 1, p. 64, doi. 10.1007/BF03179934

By:

Kim, Hyun-Sook;
Okajima, Fumikazu;
Im, Dong-Soon

Publication type:

Article

Retraction of: p2y5/LPA6 attenuates LPA1-mediated VE-cadherin translocation and cell–cell dissociation through G12/13 protein–Src–Rap1.

Published in:

Cardiovascular Research, 2012, v. 94, n. 1, p. 163, doi. 10.1093/cvr/cvs087

By:

Kimura, Takao;
Mogi, Chihiro;
Sato, Koichi;
Tomura, Hideaki;
Ohta, Hideo;
Im, Doon-Soon;
Kuwabara, Atsushi;
Kurose, Hitoshi;
Murakami, Masami;
Okajima, Fumikazu

Publication type:

Article

p2y5/LPA6 attenuates LPA1-mediated VE-cadherin translocation and cell–cell dissociation through G12/13 protein–Src–Rap1.

Published in:

Cardiovascular Research, 2011, v. 92, n. 1, p. 149, doi. 10.1093/cvr/cvr154

By:

Kimura, Takao;
Mogi, Chihiro;
Sato, Koichi;
Tomura, Hideaki;
Ohta, Hideo;
Im, Doon-Soon;
Kuwabara, Atsushi;
Kurose, Hitoshi;
Murakami, Masami;
Okajima, Fumikazu

Publication type:

Article

Protective Role of Proton-Sensing TDAG8 in Lipopolysaccharide-Induced Acute Lung Injury.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 12, p. 28931, doi. 10.3390/ijms161226145

By:

Tsurumaki, Hiroaki;
Mogi, Chihiro;
Aoki-Saito, Haruka;
Tobo, Masayuki;
Kamide, Yosuke;
Yatomi, Masakiyo;
Sato, Koichi;
Dobashi, Kunio;
Ishizuka, Tamotsu;
Hisada, Takeshi;
Yamada, Masanobu;
Okajima, Fumikazu

Publication type:

Article

Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway.

Published in:

Nature Communications, 2017, v. 8, n. 6, p. 1, doi. 10.1038/s41467-017-00037-1

By:

Morizawa, Yosuke M.;
Yuri Hirayama;
Nobuhiko Ohno;
Shinsuke Shibata;
Eiji Shigetomi;
Yang Sui;
Junichi Nabekura;
Koichi Sato;
Fumikazu Okajima;
Hirohide Takebayashi;
Hideyuki Okano;
Schuichi Koizumi

Publication type:

Article

Metal-Stimulated Interleukin-6 Production Through a Proton-Sensing Receptor, Ovarian Cancer G Protein-Coupled Receptor 1, in Human Bronchial Smooth Muscle Cells: A Response Inhibited by Dexamethasone.

Published in:

Journal of Inflammation Research, 2021, v. 14, p. 7021, doi. 10.2147/JIR.S326964

By:

Kadowaki, Maiko;
Sato, Koichi;
Kamio, Hisashi;
Kumagai, Makoto;
Sato, Rikishi;
Nyui, Takafumi;
Umeda, Yukihiro;
Waseda, Yuko;
Anzai, Masaki;
Aoki-Saito, Haruka;
Koga, Yasuhiko;
Hisada, Takeshi;
Tomura, Hideaki;
Okajima, Fumikazu;
Ishizuka, Tamotsu

Publication type:

Article

9HODE Stimulates Cell Proliferation and Extracellular Matrix Synthesis in Human Mesangial Cells via PPARγ.

Published in:

Experimental Biology & Medicine, 2004, v. 229, n. 10, p. 1053, doi. 10.1177/153537020422901010

By:

Negishi, Mayumi;
Shimizu, Hiroyuki;
Okada, Shuichi;
Kuwabara, Atsushi;
Okajima, Fumikazu;
Mori, Masatomo

Publication type:

Article

Cyclooxygenase-2 Expression and Prostaglandin E2 Production in Response to Acidic pH Through OGR1 in a Human Osteoblastic Cell Line.

Published in:

Journal of Bone & Mineral Research, 2008, v. 23, n. 7, p. 1129, doi. 10.1359/jbmr.080236

By:

Tomura, Hideaki;
Ju-Qiang Wang;
Jin-Peng Liu;
Komachi, Mayumi;
Damirin, Alatangaole;
Mogi, Chihiro;
Tobo, Masayuki;
Nochi, Hiromi;
Tamoto, Koichi;
Doon-Soon Im;
Sato, Koichi;
Okajima, Fumikazu

Publication type:

Article

Inhibition of interleukin-1β production by extracellular acidification through the TDAG8/ cAMP pathway in mouse microglia.

Published in:

Journal of Neurochemistry, 2014, v. 129, n. 4, p. 683, doi. 10.1111/jnc.12661

By:

Jin, Ye;
Sato, Koichi;
Tobo, Ayaka;
Mogi, Chihiro;
Tobo, Masayuki;
Murata, Naoya;
Ishii, Satoshi;
Im, Dong ‐ Soon;
Okajima, Fumikazu

Publication type:

Article

Angiotensin II Reduces Lipoprotein Lipase Expression in Visceral Adipose Tissue via Phospholipase C β4 Depending on Feeding but Increases Lipoprotein Lipase Expression in Subcutaneous Adipose Tissue via c-Src.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0139638

By:

Uchiyama, Tsuyoshi;
Tomono, Shoichi;
Sato, Koichi;
Nakamura, Tetsuya;
Kurabayashi, Masahiko;
Okajima, Fumikazu

Publication type:

Article

Characterization of Imidazopyridine Compounds as Negative Allosteric Modulators of Proton-Sensing GPR4 in Extracellular Acidification-Induced Responses.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0129334

By:

Tobo, Ayaka;
Tobo, Masayuki;
Nakakura, Takashi;
Ebara, Masashi;
Tomura, Hideaki;
Mogi, Chihiro;
Im, Dong-Soon;
Murata, Naoya;
Kuwabara, Atsushi;
Ito, Saki;
Fukuda, Hayato;
Arisawa, Mitsuhiro;
Shuto, Satoshi;
Nakaya, Michio;
Kurose, Hitoshi;
Sato, Koichi;
Okajima, Fumikazu

Publication type:

Article

Proton-Sensing Ovarian Cancer G Protein-Coupled Receptor 1 on Dendritic Cells Is Required for Airway Responses in a Murine Asthma Model.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0079985

By:

Aoki, Haruka;
Mogi, Chihiro;
Hisada, Takeshi;
Nakakura, Takashi;
Kamide, Yosuke;
Ichimonji, Isao;
Tomura, Hideaki;
Tobo, Masayuki;
Sato, Koichi;
Tsurumaki, Hiroaki;
Dobashi, Kunio;
Mori, Tetsuya;
Harada, Akihiro;
Yamada, Masanobu;
Mori, Masatomo;
Ishizuka, Tamotsu;
Okajima, Fumikazu

Publication type:

Article

Role of p38 mitogen-activated kinase and c-Jun terminal kinase in migration response to lysophosphatidic acid and sphingosine-1-phosphate in glioma cells.

Published in:

Oncogene, 2005, v. 24, n. 44, p. 6676, doi. 10.1038/sj.onc.1208805

By:

Malchinkhuu, Enkhzol;
Sato, Koichi;
Horiuchi, Yuta;
Mogi, Chihiro;
Ohwada, Susumu;
Ishiuchi, Shogo;
Saito, Nobuhito;
Kurose, Hitoshi;
Tomura, Hideaki;
Okajima, Fumikazu

Publication type:

Article

Unmasking of LPA.

Published in:

Journal of Neurochemistry, 2011, v. 117, n. 1, p. 164, doi. 10.1111/j.1471-4159.2011.07188.x

By:

Sato, Koichi;
Horiuchi, Yuta;
Jin, Ye;
Malchinkhuu, Enkhzol;
Komachi, Mayumi;
Kondo, Toshihiko;
Okajima, Fumikazu

Publication type:

Article

Critical role of ABCA1 transporter in sphingosine 1-phosphate release from astrocytes.

Published in:

Journal of Neurochemistry, 2007, v. 103, n. 6, p. 2610, doi. 10.1111/j.1471-4159.2007.04958.x

By:

Koichi Sato;
Enkhzol Malchinkhuu;
Yuta Horiuchi;
Chihiro Mogi;
Hideaki Tomura;
Masahiko Tosaka;
Yuhei Yoshimoto;
Atsushi Kuwabara;
Fumikazu Okajima

Publication type:

Article

Identification of autotaxin as a neurite retraction-inducing factor of PC12 cells in cerebrospinal fluid and its possible sources.

Published in:

Journal of Neurochemistry, 2005, v. 92, n. 4, p. 904, doi. 10.1111/j.1471-4159.2004.02933.x

By:

Sato, Koichi;
Malchinkhuu, Enkhzol;
Muraki, Takeshi;
Ishikawa, Koichi;
Hayashi, Kensuke;
Tosaka, Masahiko;
Mochiduki, Akikazu;
Inoue, Kinji;
Tomura, Hideaki;
Mogi, Chihiro;
Nochi, Hiromi;
Tamoto, Koichi;
Okajima, Fumikazu

Publication type:

Article

Works by Fumikazu Okajima

Extracellular acidification-induced CXCL8 production through a proton-sensing receptor OGR1 in human airway smooth muscle cells: a response inhibited by dexamethasone.

Manganese and cobalt activate zebrafish ovarian cancer G-protein-coupled receptor 1 but not GPR4.

The protective role of proton-sensing TDAG8 in the brain injury in a mouse ischemia reperfusion model.

LPA1 receptors mediate stimulation, whereas LPA2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites.

Author Correction: Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway.

Role of extracellular proton-sensing OGR1 in regulation of insulin secretion and pancreatic β-cell functions.

Growth dependency of a new human pancreatic cancer cell line, YAPC, on autocrine interleukin-1α stimulation.

Ionotropic and Metabotropic Proton-Sensing Receptors Involved in Airway Inflammation in Allergic Asthma.

Omega-3 fatty acids induce Ca<sup>2+</sup> mobilization responses in human colon epithelial cell lines endogenously expressing FFA4.

Increase in sphingolipid catabolic enzyme activity during aging.

17(R)-resolvin D1 ameliorates bleomycin-induced pulmonary fibrosis in mice.

Orally active lysophosphatidic acid receptor antagonist attenuates pancreatic cancer invasion and metastasis in vivo.

Alamandine reduces leptin expression through the c-Src/p38 MAP kinase pathway in adipose tissue.

Analysis of vasopressin-induced Ca<sup>2+</sup> increase in rat hepatocytes.

Retraction of: p2y5/LPA6 attenuates LPA1-mediated VE-cadherin translocation and cell–cell dissociation through G12/13 protein–Src–Rap1.

p2y5/LPA6 attenuates LPA1-mediated VE-cadherin translocation and cell–cell dissociation through G12/13 protein–Src–Rap1.

Protective Role of Proton-Sensing TDAG8 in Lipopolysaccharide-Induced Acute Lung Injury.

Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway.

Metal-Stimulated Interleukin-6 Production Through a Proton-Sensing Receptor, Ovarian Cancer G Protein-Coupled Receptor 1, in Human Bronchial Smooth Muscle Cells: A Response Inhibited by Dexamethasone.

9HODE Stimulates Cell Proliferation and Extracellular Matrix Synthesis in Human Mesangial Cells via PPARγ.

Cyclooxygenase-2 Expression and Prostaglandin E<sub>2</sub> Production in Response to Acidic pH Through OGR1 in a Human Osteoblastic Cell Line.

Inhibition of interleukin-1β production by extracellular acidification through the TDAG8/ cAMP pathway in mouse microglia.

Angiotensin II Reduces Lipoprotein Lipase Expression in Visceral Adipose Tissue via Phospholipase C β4 Depending on Feeding but Increases Lipoprotein Lipase Expression in Subcutaneous Adipose Tissue via c-Src.

Characterization of Imidazopyridine Compounds as Negative Allosteric Modulators of Proton-Sensing GPR4 in Extracellular Acidification-Induced Responses.

Proton-Sensing Ovarian Cancer G Protein-Coupled Receptor 1 on Dendritic Cells Is Required for Airway Responses in a Murine Asthma Model.

Role of p38 mitogen-activated kinase and c-Jun terminal kinase in migration response to lysophosphatidic acid and sphingosine-1-phosphate in glioma cells.

Unmasking of LPA.

Critical role of ABCA1 transporter in sphingosine 1-phosphate release from astrocytes.

Identification of autotaxin as a neurite retraction-inducing factor of PC12 cells in cerebrospinal fluid and its possible sources.