Works by Fuks, François

Results: 45

TET proteins: on the frenetic hunt for new cytosine modifications.

Published in:

Briefings in Functional Genomics, 2013, v. 12, n. 3, p. 191, doi. 10.1093/bfgp/elt010

By:

Delatte, Benjamin;
Fuks, François

Publication type:

Article

Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription.

Published in:

EMBO Journal, 2001, v. 20, n. 10, p. 2536, doi. 10.1093/emboj/20.10.2536

By:

Fuks, François;
burgers, Wendy A.;
Godin, Nadia;
Kasai, Masataka;
Kouzarides, Tony

Publication type:

Article

The Polycomb group protein EZH2 directly controls DNA methylation.

Published in:

2007

By:

Viré, Emmanuelle;
Brenner, Carmen;
Deplus, Rachel;
Blanchon, Loïc;
Fraga, Mario;
Didelot, Céline;
Morey, Lluis;
Van Eynde, Aleyde;
Bernard, David;
Vanderwinden, Jean-Marie;
Bollen, Mathieu;
Esteller, Manel;
Croce, Luciano Di;
de Launoit, Yvan;
Fuks, François

Publication type:

Correction Notice

The Polycomb group protein EZH2 directly controls DNA methylation.

Published in:

Nature, 2006, v. 439, n. 7078, p. 871, doi. 10.1038/nature04431

By:

Viré, Emmanuelle;
Brenner, Carmen;
Deplus, Rachel;
Blanchon, Loïc;
Fraga, Mario;
Didelot, Céline;
Morey, Lluis;
Van Eynde, Aleyde;
Bernard, David;
Vanderwinden, Jean-Marie;
Bollen, Mathieu;
Esteller, Manel;
Di Croce, Luciano;
de Launoit, Yvan;
Fuks, François

Publication type:

Article

The histone demethylase Kdm3a is essential to progression through differentiation.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 15, p. 7219, doi. 10.1093/nar/gks399

By:

Herzog, Marielle;
Josseaux, Eléonore;
Dedeurwaerder, Sarah;
Calonne, Emilie;
Volkmar, Michael;
Fuks, François

Publication type:

Article

MAGE-A1 interacts with adaptor SKIP and the deacetylase HDAC1 to repress transcription.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 14, p. 4340, doi. 10.1093/nar/gkh735

By:

Laduron, Sandra;
Deplus, Rachel;
Zhou, Sifang;
Kholmanskikh, Olga;
Godelaine, Danièle;
De Smet, Charles;
Hayward, S. Diane;
Fuks, François;
Boon, Thierry;
De Plaen, Etienne

Publication type:

Article

The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase.

Published in:

Nucleic Acids Research, 2003, v. 31, n. 9, p. 2305, doi. 10.1093/nar/gkg332

By:

Fuks, François;
Hurd, Paul J.;
Deplus, Rachel;
Kouzarides, Tony

Publication type:

Article

Dnmt3L is a transcriptional repressor that recruits histone deacetylase.

Published in:

Nucleic Acids Research, 2002, v. 30, n. 17, p. 3831, doi. 10.1093/nar/gkf509

By:

Deplus, Rachel;
Brenner, Carmen;
Burgers, Wendy A.;
Putmans, Pascale;
Kouzarides, Tony;
Launoit, Yvan de;
Fuks, François

Publication type:

Article

TET2 Deficiency Inhibits Mesoderm and Hematopoietic Differentiation in Human Embryonic Stem Cells.

Published in:

Stem Cells, 2014, v. 32, n. 8, p. 2084, doi. 10.1002/stem.1718

By:

Langlois, Thierry;
da Costa Reis Monte-Mor, Barbara;
Lenglet, Gaëlle;
Droin, Nathalie;
Marty, Caroline;
Le Couédic, Jean-Pierre;
Almire, Carole;
Auger, Nathalie;
Mercher, Thomas;
Delhommeau, François;
Christensen, Jesper;
Helin, Kristian;
Debili, Najet;
Fuks, François;
Bernard, Olivier A.;
Solary, Eric;
Vainchenker, William;
Plo, Isabelle

Publication type:

Article

DNA methyltransferase Dnmt1 associates with histone deacetylase activity.

Published in:

Nature Genetics, 2000, v. 24, n. 1, p. 88, doi. 10.1038/71750

By:

Fuks, François;
Burgers, Wendy A.;
Brehm, Alexander;
Hughes-Davies, Luke;
Kouzarides, Tony

Publication type:

Article

DNA methylation-based immune response signature improves patient diagnosis in multiple cancers.

Published in:

2017

By:

Jeschke, Jana;
Bizet, Martin;
Desmedt, Christine;
Calonne, Emilie;
Dedeurwaerder, Sarah;
Garaud, Soizic;
Koch, Alexander;
Larsimont, Denis;
Salgado, Roberto;
Van den Eynden, Gert;
Gallo, Karen Willard;
Bontempi, Gianluca;
Defrance, Matthieu;
Sotiriou, Christos;
Fuks, François;
Willard Gallo, Karen

Publication type:

journal article

Monocytes undergo multi-step differentiation in mice during oral infection by Toxoplasma gondii.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. 1, doi. 10.1038/s42003-019-0718-6

By:

Detavernier, Aurélie;
Azouz, Abdulkader;
Shehade, Hussein;
Splittgerber, Marion;
Van Maele, Laurye;
Nguyen, Muriel;
Thomas, Séverine;
Achouri, Younes;
Svec, David;
Calonne, Emilie;
Fuks, François;
Oldenhove, Guillaume;
Goriely, Stanislas

Publication type:

Article

FOXP1 is a regulator of quiescence in healthy human CD4<sup>+</sup> T cells and is constitutively repressed in T cells from patients with lymphoproliferative disorders.

Published in:

European Journal of Immunology, 2017, v. 47, n. 1, p. 168, doi. 10.1002/eji.201646373

By:

Garaud, Soizic;
Roufosse, Florence;
De Silva, Pushpamali;
Gu‐Trantien, Chunyan;
Lodewyckx, Jean‐Nicolas;
Duvillier, Hugues;
Dedeurwaerder, Sarah;
Bizet, Martin;
Defrance, Matthieu;
Fuks, François;
Bex, Françoise;
Willard‐Gallo, Karen

Publication type:

Article

Methylglyoxal: a novel upstream regulator of DNA methylation.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2023, v. 42, n. 1, p. 1, doi. 10.1186/s13046-023-02637-w

By:

Dube, Gaurav;
Tiamiou, Assia;
Bizet, Martin;
Boumahd, Yasmine;
Gasmi, Imène;
Crake, Rebekah;
Bellier, Justine;
Nokin, Marie-Julie;
Calonne, Emilie;
Deplus, Rachel;
Wissocq, Tom;
Peulen, Olivier;
Castronovo, Vincent;
Fuks, François;
Bellahcène, Akeila

Publication type:

Article

A comprehensive overview of Infinium HumanMethylation450 data processing.

Published in:

Briefings in Bioinformatics, 2014, v. 15, n. 6, p. 929, doi. 10.1093/bib/bbt054

By:

Dedeurwaerder, Sarah;
Defrance, Matthieu;
Bizet, Martin;
Calonne, Emilie;
Bontempi, Gianluca;
Fuks, François

Publication type:

Article

Correction to: Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth.

Published in:

2018

By:

Wang, Yuzhu;
He, Tao;
Herman, James G.;
Linghu, Enqiang;
Yang, Yunsheng;
Fuks, François;
Zhou, Fuyou;
Song, Linjie;
Guo, Mingzhou

Publication type:

Correction Notice

Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth.

Published in:

Clinical Epigenetics, 2017, v. 9, p. 1, doi. 10.1186/s13148-017-0417-4

By:

Yuzhu Wang;
Tao He;
Herman, James G.;
Enqiang Linghu;
Yunsheng Yang;
Fuks, François;
Fuyou Zhou;
Linjie Song;
Mingzhou Guo

Publication type:

Article

Playing TETris with DNA modifications.

Published in:

EMBO Journal, 2014, v. 33, n. 11, p. 1198, doi. 10.15252/embj.201488290

By:

Delatte, Benjamin;
Deplus, Rachel;
Fuks, François

Publication type:

Article

Policy brief – cancer research in Belgium.

Published in:

Archives of Public Health, 2024, v. 82, n. 1, p. 1, doi. 10.1186/s13690-024-01369-3

By:

Toungouz, Gordana Raicevic;
Poirel, Hélène A.;
Schittecatte, Gabrielle;
Van Den Bulcke, Marc;
Camille, Andries;
Yves, Beguin;
Sofie, Bekaert;
Geert, Berx;
Cedric, Blanpain;
Karine, Breckpot;
Pierre, Close;
Stefan, Constantinescu;
An, Coosemans;
Frederik, Coopens;
René, Custers;
De Jacques, Greve;
De Katleen, Preter;
François, Fuks;
Lode, Godderis;
Isabelle, Houbracken

Publication type:

Article

A multiomics dataset for the study of RNA modifications in human macrophage differentiation and polarisation.

Published in:

Scientific Data, 2024, v. 11, n. 1, p. 1, doi. 10.1038/s41597-024-03076-8

By:

Pinello, Natalia;
Song, Renhua;
Lee, Quintin;
Calonne, Emilie;
Larance, Mark;
Fuks, François;
Wong, Justin J. -L.

Publication type:

Article

Functional Connection between Deimination and Deacetylation of Histones.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 18, p. 4982, doi. 10.1128/MCB.00285-09

By:

Denis, Hélène;
Deplus, Rachel;
Putmans, Pascale;
Yamada, Michiyuki;
Métivier, Raphaël;
Fuks, François

Publication type:

Article

The N6-methyladenosine RNA epigenetic modification modulates the amplification of coxsackievirus B1 in human pancreatic beta cells.

Published in:

Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2024.1501061

By:

Bonfim, Maressa Fernandes;
Aitchedji, Camille;
Van Goethem, Flore;
Sauvage, Lionel;
Poinsot, Thibault;
Calonne, Emilie;
Deplus, Rachel;
Fuks, François;
Eizirik, Decio L.;
Op de Beeck, Anne

Publication type:

Article

The BRCA2 activation domain associates with and is phosphorylated by a cellular protein kinase.

Published in:

Oncogene, 2000, v. 19, n. 38, p. 4441, doi. 10.1038/sj.onc.1203793

By:

Milner, Jonathan;
Fuks, François;
Hughes-Davies, Luke;
Kouzarides, Tony

Publication type:

Article

BRCA2 associates with acetyltransferase activity when bound to P/CAF.

Published in:

Oncogene, 1998, v. 17, n. 19, p. 2531, doi. 10.1038/sj.onc.1202475

By:

Fuks, François;
Milner, Jonathan;
Kouzarides, Tony

Publication type:

Article

Citrullination of DNMT3A by PADI4 regulates its stability and controls DNA methylation.

Published in:

Nucleic Acids Research, 2014, v. 42, n. 13, p. 8285, doi. 10.1093/nar/gku522

By:

Deplus, Rachel;
Denis, Hélène;
Putmans, Pascale;
Calonne, Emilie;
Fourrez, Marie;
Yamamoto, Kazuhiko;
Suzuki, Akari;
Fuks, François

Publication type:

Article

Buffy coat signatures of breast cancer risk in a prospective cohort study.

Published in:

Clinical Epigenetics, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13148-023-01509-6

By:

Chung, Felicia Fei-Lei;
Maldonado, Sandra González;
Nemc, Amelie;
Bouaoun, Liacine;
Cahais, Vincent;
Cuenin, Cyrille;
Salle, Aurelie;
Johnson, Theron;
Ergüner, Bekir;
Laplana, Marina;
Datlinger, Paul;
Jeschke, Jana;
Weiderpass, Elisabete;
Kristensen, Vessela;
Delaloge, Suzette;
Fuks, François;
Risch, Angela;
Ghantous, Akram;
Plass, Christoph;
Bock, Christoph

Publication type:

Article

5-hydroxymethylcytosine marks promoters in colon that resist DNA hypermethylation in cancer.

Published in:

Genome Biology, 2015, v. 16, n. 1, p. 69, doi. 10.1186/s13059-015-0605-5

By:

Uribe-Lewis, Santiago;
Stark, Rory;
Carroll, Thomas;
Dunning, Mark J;
Bachman, Martin;
Yoko Ito;
Stojic, Lovorka;
Silvia Halim;
Vowler, Sarah L;
Lynch, Andy G;
Delatte, Benjamin;
de Bony, Eric J;
Colin, Laurence;
Defrance, Matthieu;
Krueger, Felix;
Silva, Ana-Luisa;
Hoopen, Rogier ten;
Ibrahim, Ashraf EK;
Fuks, François;
Murrell, Adele

Publication type:

Article

Tet-dependent 5-hydroxymethyl-Cytosine modification of mRNA regulates axon guidance genes in Drosophila.

Published in:

PLoS ONE, 2024, v. 19, n. 2, p. 1, doi. 10.1371/journal.pone.0293894

By:

Singh, Badri Nath;
Tran, Hiep;
Kramer, Joseph;
Kirichenko, Elmira;
Changela, Neha;
Wang, Fei;
Feng, Yaping;
Kumar, Dibyendu;
Tu, Min;
Lan, Jie;
Bizet, Martin;
Fuks, François;
Steward, Ruth

Publication type:

Article

TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS.

Published in:

EMBO Journal, 2013, v. 32, n. 5, p. 645, doi. 10.1038/emboj.2012.357

By:

Deplus, Rachel;
Delatte, Benjamin;
Schwinn, Marie K;
Defrance, Matthieu;
Méndez, Jacqui;
Murphy, Nancy;
Dawson, Mark A;
Volkmar, Michael;
Putmans, Pascale;
Calonne, Emilie;
Shih, Alan H;
Levine, Ross L;
Bernard, Olivier;
Mercher, Thomas;
Solary, Eric;
Urh, Marjeta;
Daniels, Danette L;
Fuks, François

Publication type:

Article

DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients.

Published in:

EMBO Journal, 2012, v. 31, n. 6, p. 1405, doi. 10.1038/emboj.2011.503

By:

Volkmar, Michael;
Dedeurwaerder, Sarah;
Cunha, Daniel A;
Ndlovu, Matladi N;
Defrance, Matthieu;
Deplus, Rachel;
Calonne, Emilie;
Volkmar, Ute;
Igoillo-Esteve, Mariana;
Naamane, Najib;
Del Guerra, Silvia;
Masini, Matilde;
Bugliani, Marco;
Marchetti, Piero;
Cnop, Miriam;
Eizirik, Decio L;
Fuks, François

Publication type:

Article

Myc represses transcription through recruitment of DNA methyltransferase corepressor.

Published in:

EMBO Journal, 2005, v. 24, n. 2, p. 336, doi. 10.1038/sj.emboj.7600509

By:

Brenner, Carmen;
Deplus, Rachel;
Didelot, Céline;
Loriot, Axelle;
Viré, Emmanuelle;
De Smet, Charles;
Gutierrez, Arantxa;
Danovi, Davide;
Bernard, David;
Boon, Thierry;
Giuseppe Pelicci, Pier;
Amati, Bruno;
Kouzarides, Tony;
de Launoit, Yvan;
Di Croce, Luciano;
Fuks, François

Publication type:

Article

De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 11, p. 1176, doi. 10.1038/nsmb.1476

By:

Epsztejn-Litman, Silvina;
Feldman, Nirit;
Abu-Remaileh, Monther;
Shufaro, Yoel;
Gerson, Ariela;
Ueda, Jun;
Deplus, Rachel;
Fuks, François;
Shinkai, Yoichi;
Cedar, Howard;
Bergman, Yehudit

Publication type:

Article

Aberrant Promoter Methylation and Expression of UTF1 during Cervical Carcinogenesis.

Published in:

PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0042704

By:

Guenin, Samuel;
Mouallif, Mustapha;
Deplus, Rachel;
Lampe, Xavier;
Krusy, Nathalie;
Calonne, Emilie;
Delbecque, Katty;
Kridelka, Frederic;
Fuks, François;
Ennaji, My Mustapha;
Delvenne, Philippe;
Castresana, Javier S.

Publication type:

Article

Journal club.

Published in:

Nature, 2010, v. 466, n. 7305, p. 417, doi. 10.1038/466417f

By:

Fuks, François

Publication type:

Article

The transcription factors Runx3 and ThPOK cross-regulate acquisition of cytotoxic function by human Th1 lymphocytes.

Published in:

eLife, 2018, p. 1, doi. 10.7554/eLife.30496

By:

Serroukh, Yasmina;
Gu-Trantien, Chunyan;
Kashani, Baharak Hooshiar;
Defrance, Matthieu;
Thien-Phong Vu Manh;
Azouz, Abdulkader;
Detavernier, Aurélie;
Hoyois, Alice;
Das, Jishnu;
Bizet, Martin;
Pollet, Emeline;
Tabbuso, Tressy;
Calonne, Emilie;
van Gisbergen, Klaas;
Dalod, Marc;
Fuks, François;
Goriely, Stanislas;
Marchant, Arnaud

Publication type:

Article

Regulation of mammalian DNA methyltransferases: a route to new mechanisms.

Published in:

EMBO Reports, 2011, v. 12, n. 7, p. 647, doi. 10.1038/embor.2011.110

By:

Denis, Hélène;
Ndlovu, 'Matladi N;
Fuks, François

Publication type:

Article

Genome-wide hydroxymethylcytosine pattern changes in response to oxidative stress.

Published in:

Scientific Reports, 2015, p. 12714, doi. 10.1038/srep12714

By:

Delatte, Benjamin;
Jeschke, Jana;
Defrance, Matthieu;
Bachman, Martin;
Creppe, Catherine;
Calonne, Emilie;
Bizet, Martin;
Deplus, Rachel;
Marroquí, Laura;
Libin, Myriam;
Ravichandran, Mirunalini;
Mascart, Françoise;
Eizirik, Decio L.;
Murrell, Adele;
Jurkowski, Tomasz P.;
Fuks, François

Publication type:

Article

EOMES interacts with RUNX3 and BRG1 to promote innate memory cell formation through epigenetic reprogramming.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11233-6

By:

Istaces, Nicolas;
Splittgerber, Marion;
Lima Silva, Viviana;
Nguyen, Muriel;
Thomas, Séverine;
Le, Aurore;
Achouri, Younes;
Calonne, Emilie;
Defrance, Matthieu;
Fuks, François;
Goriely, Stanislas;
Azouz, Abdulkader

Publication type:

Article

Improving Infinium MethylationEPIC data processing: re-annotation of enhancers and long noncoding RNA genes and benchmarking of normalization methods.

Published in:

Epigenetics, 2022, v. 17, n. 13, p. 2434, doi. 10.1080/15592294.2022.2135201

By:

Bizet, Martin;
Defrance, Matthieu;
Calonne, Emilie;
Bontempi, Gianluca;
Sotiriou, Christos;
Fuks, François;
Jeschke, Jana

Publication type:

Article

Improving Infinium MethylationEPIC data processing: re-annotation of enhancers and long noncoding RNA genes and benchmarking of normalization methods.

Published in:

Epigenetics, 2022, v. 17, n. 12, p. 2434, doi. 10.1080/15592294.2022.2135201

By:

Bizet, Martin;
Defrance, Matthieu;
Calonne, Emilie;
Bontempi, Gianluca;
Sotiriou, Christos;
Fuks, François;
Jeschke, Jana

Publication type:

Article

The chromatin remodelling protein LSH/HELLS regulates the amount and distribution of DNA hydroxymethylation in the genome.

Published in:

Epigenetics, 2022, v. 17, n. 4, p. 422, doi. 10.1080/15592294.2021.1917152

By:

De Dieuleveult, Maud;
Bizet, Martin;
Colin, Laurence;
Calonne, Emilie;
Bachman, Martin;
Li, Chao;
Stancheva, Irina;
Miotto, Benoit;
Fuks, François;
Deplus, Rachel

Publication type:

Article

Methylation of TMEM176A is an independent prognostic marker and is involved in human colorectal cancer development.

Published in:

Epigenetics, 2017, v. 12, n. 7, p. 575, doi. 10.1080/15592294.2017.1341027

By:

Gao, Dan;
Han, Yingjie;
Yang, Yang;
Herman, James G.;
Linghu, Enqiang;
Zhan, Qimin;
Fuks, François;
Lu, Zhi John;
Guo, Mingzhou

Publication type:

Article

Epigenetic regulation of DACH1, a novel Wnt signaling component in colorectal cancer.

Published in:

Epigenetics, 2013, v. 8, n. 12, p. 1373, doi. 10.4161/epi.26781

By:

Wenji Yan;
Kongming Wu;
Herman, James G.;
Brock, Malcolm V.;
Fuks, François;
Lili Yang;
Hongbin Zhu;
Yazhuo Li;
Yunsheng Yang;
Mingzhou Guo

Publication type:

Article

Dynamic changes in RNA m<sup>6</sup>A and 5 hmC influence gene expression programs during macrophage differentiation and polarisation.

Published in:

Cellular & Molecular Life Sciences, 2024, v. 81, n. 1, p. 1, doi. 10.1007/s00018-024-05261-9

By:

Pinello, Natalia;
Song, Renhua;
Lee, Quintin;
Calonne, Emilie;
Duan, Kun-Long;
Wong, Emilie;
Tieng, Jessica;
Mehravar, Majid;
Rong, Bowen;
Lan, Fei;
Roediger, Ben;
Ma, Cheng-Jie;
Yuan, Bi-Feng;
Rasko, John E. J.;
Larance, Mark;
Ye, Dan;
Fuks, François;
Wong, Justin J.-L.

Publication type:

Article

DNA methylome profiling beyond promoters - taking an epigenetic snapshot of the breast tumor microenvironment.

Published in:

FEBS Journal, 2015, v. 282, n. 9, p. 1801, doi. 10.1111/febs.13125

By:

Jeschke, Jana;
Collignon, Evelyne;
Fuks, François

Publication type:

Article