Works by Fugger, Lars

Results: 58

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance.

Published in:

Nature Immunology, 2009, v. 10, n. 6, p. 636, doi. 10.1038/ni.1728

By:

Tenzer, Stefan;
Wee, Edmund;
Burgevin, Anne;
Stewart-Jones, Guillaume;
Friis, Lone;
Lamberth, Kasper;
Chang, Chih-hao;
Harndahl, Mikkel;
Weimershaus, Mirjana;
Gerstoft, Jan;
Akkad, Nadja;
Klenerman, Paul;
Fugger, Lars;
Jones, E Yvonne;
McMichael, Andrew J;
Buus, Søren;
Schild, Hansjörg;
van Endert, Peter;
Iversen, Astrid K N

Publication type:

Article

Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope.

Published in:

Nature Immunology, 2006, v. 7, n. 2, p. 179, doi. 10.1038/ni1298

By:

Iversen, Astrid K. N.;
Stewart-Jones, Guillaume;
Learn, Gerald H.;
Christie, Natasha;
Sylvester-Hviid, Christina;
Armitage, Andrew E.;
Kaul, Rupert;
Beattie, Tara;
Lee, Jean K.;
Yanping Li;
Chotiyarnwong, Pojchong;
Tao Dong;
Xiaoning Xu;
Luscher, Mark A.;
MacDonald, Kelly;
Ullum, Henrik;
Klarlund-Pedersen, Bente;
Skinhøj, Peter;
Fugger, Lars;
Buus, Søren

Publication type:

Article

The nature of molecular recognition by T cells.

Published in:

Nature Immunology, 2003, v. 4, n. 3, p. 217, doi. 10.1038/ni0303-217

By:

Davis, Simon J.;
Ikemizu, Shinji;
Evans, Edward J.;
Fugger, Lars;
Bakker, Talitha R.;
van der Merwe, P. Anton

Publication type:

Article

A functional and structural basis for TCR cross-reactivity in multiple sclerosis.

Published in:

Nature Immunology, 2002, v. 3, n. 10, p. 940, doi. 10.1038/ni835

By:

Lang, Heather L.E.;
Jacobsen, Helle;
Ikemizu, Shinji;
Andersson, Christina;
Harlos, Karl;
Madsen, Lars;
Hjorth, Peter;
Sondergaard, Leif;
Svejgaard, Arne;
Wucherpfennig, Kai;
Stuart, David I.;
Bell, John I.;
Jones, E. Yvonne;
Fugger, Lars

Publication type:

Article

Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP.

Published in:

Nature Immunology, 2002, v. 3, n. 2, p. 169, doi. 10.1038/ni754

By:

Manoury, Bénédicte;
Mazzeo, Daniela;
Fugger, Lars;
Viner, Nick;
Ponsford, Mary;
Streeter, Heather;
Mazza, Graziella;
Wraith, David C.;
Watts, Colin

Publication type:

Article

POSSIBLE CORRELATION OF TNFα-PRODUCTION WITH -RFLP IN HUMANS.

Published in:

European Journal of Haematology, 1989, v. 43, n. 3, p. 255, doi. 10.1111/j.1600-0609.1989.tb00292.x

By:

Fugger, Lars;
Bendtzen, Klaus;
Morling, Niels;
Ryder, Lars;
Svejgaard, Arne

Publication type:

Article

Functional epistasis on a common MHC haplotype associated with multiple sclerosis.

Published in:

Nature, 2006, v. 443, n. 7111, p. 574, doi. 10.1038/nature05133

By:

Gregersen, Jon W.;
Kranc, Kamil R.;
Ke, Xiayi;
Svendsen, Pia;
Madsen, Lars S.;
Thomsen, Allan Randrup;
Cardon, Lon R.;
Bell, John I.;
Fugger, Lars

Publication type:

Article

The spatial RNA integrity number assay for in situ evaluation of transcriptome quality.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-020-01573-1

By:

Kvastad, Linda;
Carlberg, Konstantin;
Larsson, Ludvig;
Villacampa, Eva Gracia;
Stuckey, Alexander;
Stenbeck, Linnea;
Mollbrink, Annelie;
Zamboni, Margherita;
Magnusson, Jens Peter;
Basmaci, Elisa;
Shamikh, Alia;
Prochazka, Gabriela;
Schaupp, Anna-Lena;
Borg, Åke;
Fugger, Lars;
Nistér, Monica;
Lundeberg, Joakim

Publication type:

Article

Immunological reclassification of 22 children with a former diagnosis of non-T, non-B ALL.

Published in:

European Journal of Haematology, 1987, v. 39, n. 4, p. 369, doi. 10.1111/j.1600-0609.1987.tb00785.x

By:

Fugger, Lars;
Platz, Per;
Ryder, Lars;
Svejgaard, Arne;
Heldrup, Jesper;
Hertz, Henrik;
Yssing, Minna

Publication type:

Article

A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor.

Published in:

Nature Genetics, 1999, v. 23, n. 3, p. 343, doi. 10.1038/15525

By:

Madsen, Lars S.;
Andersson, Ellen Christina;
Jansson, Liselotte;
Krogsgaard, Michelle;
Andersen, Claus B.;
Engberg, Jan;
Strominger, Jack L.;
Svejgaard, Arne;
Hjorth, Jens Peter;
Holmdahl, Rikard;
Wucherpfennig, Kai W.;
Fugger, Lars

Publication type:

Article

APOBEC3G-Induced Hypermutation of Human Immunodeficiency Virus Type-1 Is Typically a Discrete "All or Nothing" Phenomenon.

Published in:

PLoS Genetics, 2012, v. 8, n. 3, p. 1, doi. 10.1371/journal.pgen.1002550

By:

Armitage, Andrew E.;
Deforche, Koen;
Chang, Chih-hao;
Wee, Edmund;
Kramer, Beatrice;
Welch, John J.;
Gerstoft, Jan;
Fugger, Lars;
McMichael, Andrew;
Rambaut, Andrew;
Iversen, Astrid K. N.

Publication type:

Article

Immunopathology of multiple sclerosis.

Published in:

2015

By:

Dendrou, Calliope A;
Fugger, Lars;
Friese, Manuel A

Publication type:

journal article

Immunopathology of multiple sclerosis.

Published in:

Nature Reviews Immunology, 2015, v. 15, n. 9, p. 545, doi. 10.1038/nri3871

By:

Dendrou, Calliope A.;
Fugger, Lars;
Friese, Manuel A.

Publication type:

Article

Characterization of T‐cell receptor transgenic mice recognizing immunodominant HLA‐DQ2.5‐restricted gluten epitopes.

Published in:

European Journal of Immunology, 2021, v. 51, n. 4, p. 1002, doi. 10.1002/eji.202048859

By:

Lindstad, Christian B.;
Qiao, Shuo‐Wang;
Johannesen, Marie K.;
Fugger, Lars;
Sollid, Ludvig M.;
du Pré, M. Fleur

Publication type:

Article

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders.

Published in:

Nature Genetics, 2015, v. 47, n. 7, p. 717, doi. 10.1038/ng.3304

By:

Taylor, Jenny C;
Copley, Richard R;
Craft, Jude;
Howard, Malcolm;
Pagnamenta, Alistair;
Popitsch, Niko;
Tomlinson, Ian;
Bull, Katherine;
Cais, Ondrej;
Greger, Ingo H;
Cario, Holger;
Chapel, Helen;
Patel, Smita Y;
van Schouwenburg, Pauline A;
Cornall, Richard;
Dahan, Karin;
Dendrou, Calliope;
Fugger, Lars;
Devuyst, Olivier;
Fenwick, Aimée L

Publication type:

Article

From genes to function: the next challenge to understanding multiple sclerosis.

Published in:

2009

By:

Fugger, Lars;
Friese, Manuel A.;
Bell, John I.

Publication type:

journal article

MHC class II proteins and disease: a structural perspective.

Published in:

2006

By:

Jones, E. Yvonne;
Fugger, Lars;
Strominger, Jack L.;
Siebold, Christian

Publication type:

journal article

Stimulation of orexin/hypocretin neurones by thyrotropin-releasing hormone.

Published in:

Journal of Physiology, 2009, v. 587, n. 6, p. 1179, doi. 10.1113/jphysiol.2008.167940

By:

González, J. Antonio;
Horjales-Araujo, Emilia;
Fugger, Lars;
Broberger, Christian;
Burdakov, Denis

Publication type:

Article

Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?

Published in:

Brain: A Journal of Neurology, 2005, v. 128, n. 8, p. 1747, doi. 10.1093/brain/awh578

By:

Manuel A. Friese;
Lars Fugger

Publication type:

Article

Linkage and association analysis of susceptibility regions on chromosomes 5 and 6 in 106 Scandinavian sibling pair families with multiple sclerosis.

Published in:

Annals of Neurology, 1999, v. 46, n. 4, p. 612, doi. 10.1002/1531-8249(199910)46:4<612::AID-ANA9>3.0.CO;2-W

By:

Oturai, Annette;
Larsen, Flemming;
Ryder, Lars P.;
Madsen, Hans O.;
Hillert, Jan;
Fredrikson, Sten;
Sandberg-Wollheim, Magnhild;
Laaksonen, Mikko;
Koch-Henriksen, Nils;
Sawcer, Stephen;
Fugger, Lars;
Sorensen, Per S.;
Svejgaard, Arne

Publication type:

Article

Prediction of Peptide Affinity to HLA DRB1*0401.

Published in:

International Archives of Allergy & Immunology, 1994, v. 105, n. 1, p. 1, doi. 10.1159/000236795

By:

Rothbard, Jonathan B.;
Marshall, Keith;
Wilson, Jeff;
Fugger, Lars;
Zaller, Dennis

Publication type:

Article

HLA class II transgenic mice: models of the human CD4+ T-cell immune response.

Published in:

Immunological Reviews, 1999, v. 172, n. 1, p. 335, doi. 10.1111/j.1600-065X.1999.tb01377.x

By:

Sonderstrup, Grete;
Cope, Andrew P.;
Patel, Salil;
Congia, Mauro;
Hain, Norbert;
Hall, Frances C.;
Parry, Sarah L.;
Fugger, Lars H.;
Michie, Sara;
McDevitt, Hugh O.

Publication type:

Article

Transgenic mouse model of rheumatoid arthritis.

Published in:

Immunological Reviews, 1999, v. 169, n. 1, p. 161, doi. 10.1111/j.1600-065X.1999.tb01314.x

By:

Holmdahl, Rikard;
Andersson, Ellen Christina;
Andersen, Claus B.;
Svejgaard, Arne;
Fugger, Lars

Publication type:

Article

Recovery from COVID-19 in a B-cell-depleted multiple sclerosis patient.

Published in:

Multiple Sclerosis Journal, 2020, v. 26, n. 10, p. 1261, doi. 10.1177/1352458520943791

By:

Wurm, Hannah;
Attfield, Kate;
Iversen, Astrid KN;
Gold, Ralf;
Fugger, Lars;
Haghikia, Aiden

Publication type:

Article

Orexin neurons as conditional glucosensors: paradoxical regulation of sugar sensing by intracellular fuels.

Published in:

Journal of Physiology, 2011, v. 589, n. 23, p. 5701, doi. 10.1113/jphysiol.2011.217000

By:

Venner, Anne;
Karnani, Mahesh M.;
Gonzalez, J. Antonio;
Jensen, Lise T.;
Fugger, Lars;
Burdakov, Denis

Publication type:

Article

Direct and indirect control of orexin/hypocretin neurons by glycine receptors.

Published in:

Journal of Physiology, 2011, v. 589, n. 3, p. 639, doi. 10.1113/jphysiol.2010.198457

By:

Karnani, Mahesh M.;
Venner, Anne;
Jensen, Lise T.;
Fugger, Lars;
Burdakov, Denis

Publication type:

Article

Structural and regulatory diversity shape HLA-C protein expression levels.

Published in:

Nature Communications, 2017, v. 8, n. 6, p. 15924, doi. 10.1038/ncomms15924

By:

Kaur, Gurman;
Gras, Stephanie;
Mobbs, Jesse I.;
Vivian, Julian P.;
Cortes, Adrian;
Barber, Thomas;
Kuttikkatte, Subita Balaram;
Jensen, Lise Torp;
Attfield, Kathrine E.;
Dendrou, Calliope A.;
Carrington, Mary;
McVean, Gil;
Purcell, Anthony W.;
Rossjohn, Jamie;
Fugger, Lars

Publication type:

Article

Bridging the gap from genetic association to functional understanding: the next generation of mouse models of multiple sclerosis.

Published in:

Immunological Reviews, 2012, v. 248, n. 1, p. 10, doi. 10.1111/j.1600-065X.2012.01132.x

By:

Attfield, Kathrine E.;
Dendrou, Calliope A.;
Fugger, Lars

Publication type:

Article

Natural killer cells and their receptors in multiple sclerosis.

Published in:

Brain: A Journal of Neurology, 2013, v. 136, n. 9, p. 2657, doi. 10.1093/brain/aws159

By:

Kaur, Gurman;
Trowsdale, John;
Fugger, Lars

Publication type:

Article

Targeting ASIC1 in primary progressive multiple sclerosis: evidence of neuroprotection with amiloride.

Published in:

Brain: A Journal of Neurology, 2013, v. 136, n. 1, p. 106, doi. 10.1093/brain/aws325

By:

Arun, Tarunya;
Tomassini, Valentina;
Sbardella, Emilia;
de Ruiter, Michiel B.;
Matthews, Lucy;
Leite, Maria Isabel;
Gelineau-Morel, Rose;
Cavey, Ana;
Vergo, Sandra;
Craner, Matt;
Fugger, Lars;
Rovira, Alex;
Jenkinson, Mark;
Palace, Jacqueline

Publication type:

Article

Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model.

Published in:

Brain: A Journal of Neurology, 2011, v. 134, n. 2, p. 571, doi. 10.1093/brain/awq337

By:

Vergo, Sandra;
Craner, Matthew J.;
Etzensperger, Ruth;
Attfield, Kathrine;
Friese, Manuel A.;
Newcombe, Jia;
Esiri, Margaret;
Fugger, Lars

Publication type:

Article

T cells and microglia as drivers of multiple sclerosis pathology.

Published in:

Brain: A Journal of Neurology, 2007, v. 130, n. 11, p. 2755, doi. 10.1093/brain/awm246

By:

Manuel A. Friese;
Lars Fugger

Publication type:

Article

Weighing in on autoimmune disease: Big data tip the scale.

Published in:

Nature Medicine, 2013, v. 19, n. 2, p. 138, doi. 10.1038/nm.3087

By:

Dendrou, Calliope A;
Bell, John I;
Fugger, Lars

Publication type:

Article

Autoimmunity's next top models.

Published in:

2012

By:

Wekerle, Hartmut;
Flügel, Alexander;
Fugger, Lars;
Schett, Georg;
Serreze, David

Publication type:

Opinion

Axonal injury in reverse.

Published in:

Nature Medicine, 2011, v. 17, n. 4, p. 423, doi. 10.1038/nm0411-423

By:

Craner, Matt J.;
Fugger, Lars

Publication type:

Article

Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis.

Published in:

Nature Medicine, 2008, v. 14, n. 11, p. 1227, doi. 10.1038/nm.1881

By:

Friese, Manuel A.;
Jakobsen, Karen B;
Friis, Lone;
Etzensperger, Ruth;
Craner, Matthew J.;
McMahon, Róisín M.;
Jensen, Lise T.;
Huygelen, Véronique;
Jones, E. Yvonne;
Bell, John I.;
Fugger, Lars

Publication type:

Article

Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system.

Published in:

Nature Medicine, 2007, v. 13, n. 12, p. 1483, doi. 10.1038/nm1668

By:

Friese, Manuel A.;
Craner, Matthew J.;
Etzensperger, Ruth;
Vergo, Sandra;
Wemmie, John A.;
Welsh, Michael J.;
Vincent, Angela;
Fugger, Lars

Publication type:

Article

Use of Calcium Channel Blockers and Parkinson’s Disease.

Published in:

2012

By:

Pasternak, Björn;
Svanström, Henrik;
Nielsen, Nete M.;
Fugger, Lars;
Melbye, Mads;
Hviid, Anders

Publication type:

Journal Article

Use of Calcium Channel Blockers and Parkinson’s Disease.

Published in:

American Journal of Epidemiology, 2012, v. 175, n. 7, p. 627, doi. 10.1093/aje/kwr362

By:

Pasternak, Björn;
Svanström, Henrik;
Nielsen, Nete M.;
Fugger, Lars;
Melbye, Mads;
Hviid, Anders

Publication type:

Article

Misfiring in multiple sclerosis: cerebellar channelopathy, a potential novel target?

Published in:

2012

By:

Craner MJ;
Fugger L;
Craner, Matt J;
Fugger, Lars

Publication type:

Editorial

Misfiring in multiple sclerosis.

Published in:

Annals of Neurology, 2012, v. 71, n. 4, p. 437, doi. 10.1002/ana.23537

By:

Craner, Matt J.;
Fugger, Lars

Publication type:

Article

Pathogenic CD8(+) T cells in multiple sclerosis.

Published in:

2009

By:

Friese MA;
Fugger L;
Friese, Manuel A;
Fugger, Lars

Publication type:

journal article

Pathogenic CD8+ T cells in multiple sclerosis.

Published in:

Annals of Neurology, 2009, v. 66, n. 2, p. 132, doi. 10.1002/ana.21744

By:

Friese, Manuel A.;
Fugger, Lars

Publication type:

Article

Metabolism-Independent Sugar Sensing in Central Orexin Neurons.

Published in:

Diabetes, 2008, v. 57, n. 10, p. 2569, doi. 10.2337/db08-0548

By:

González, J. Antonio;
Jensen, Lise T.;
Fugger, Lars;
Burdakov, Denis

Publication type:

Article

Multiple sclerosis: MHC associations and therapeutic implications.

Published in:

Expert Reviews in Molecular Medicine, 2005, v. 7, n. 3, p. 1, doi. 10.1017/S1462399405008914

By:

Holmes, Samantha;
Friese, Manuel A.;
Siebold, Christian;
Jones, E. Yvonne;
Bell, John;
Fugger, Lars

Publication type:

Article

The Human Cell Atlas.

Published in:

eLife, 2017, p. 1, doi. 10.7554/eLife.27041

By:

REGEV, AVIV;
TEICHMANN, SARAH A.;
LANDER, ERIC S.;
AMIT, IDO;
BENOIST, CHRISTOPHE;
BIRNEY, EWAN;
BODENMILLER, BERND;
CAMPBELL, PETER;
CARNINCI, PIERO;
CLATWORTHY, MENNA;
CLEVERS, HANS;
DEPLANCKE, BART;
DUNHAM, IAN;
EBERWINE, JAMES;
EILS, ROLAND;
ENARD, WOLFGANG;
FARMER, ANDREW;
FUGGER, LARS;
GÖTTGENS, BERTHOLD;
HACOHEN, NIR

Publication type:

Article

Limited Protective Effect of the CCR5Δ32/ CCR5Δ32 Genotype on Human Immunodeficiency Virus Infection Incidence in a Cohort of Patients with Hemophilia and Selection for Genotypic X4 Virus.

Published in:

Journal of Infectious Diseases, 2003, v. 187, n. 2, p. 215, doi. 10.1086/345881

By:

Iversen, Astrid K.N.;
Christiansen, Claus Bohn;
Attermann, Jørn;
Eugen-Olsen, Jesper;
Schulman, Sam;
Berntorp, Erik;
Ingerslev, Jørgen;
Fugger, Lars;
Scheibel, Elma;
Tengborn, Lilian;
Gerstoft, Jan;
Dickmeiss, Ebbe;
Svejgaard, Arne;
Skinhøj, Peter

Publication type:

Article

Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice.

Published in:

European Journal of Immunology, 2004, v. 34, n. 5, p. 1251, doi. 10.1002/eji.200324354

By:

Rich, Cathleen;
Link, Jason M.;
Zamora, Alex;
Jacobsen, Helle;
Meza-Romero, Roberto;
Offner, Halina;
Jones, Richard;
Burrows, Gregory G.;
Fugger, Lars;
Vandenbark, Arthur A.

Publication type:

Article

Multiple cross-reactive self-ligands for Borrelia burgdorferi-specific HLA-DR4-restricted T cells.

Published in:

European Journal of Immunology, 2000, v. 30, n. 2, p. 448, doi. 10.1002/1521-4141(200002)30:2<448::AID-IMMU448>3.0.CO;2-9

By:

Maier, Bert;
Molinger, Marc;
Cope, Andrew P.;
Fugger, Lars;
Schneider-Mergener, Jens;
Sønderstrup, Grete;
Kamradt, Thomas;
Kramer, Achim

Publication type:

Article

HLA binding and T cell recognition of a tissue transglutaminase-modified gliadin epitope.

Published in:

European Journal of Immunology, 1999, v. 29, n. 8, p. 2506, doi. 10.1002/(SICI)1521-4141(199908)29:08<2506::AID-IMMU2506>3.0.CO;2-9

By:

Quarsten, Hanne;
Molberg, Øyvind;
Fugger, Lars;
McAdam, Stephen N.;
Sollid, Ludvig M.

Publication type:

Article